why is iv protonix used for short term treatment

by Prof. Drake Bechtelar Published 3 years ago Updated 2 years ago

Pantoprazole

Pantoprazole is used to treat certain stomach and esophagus problems.

Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease

Gastroesophageal Reflux Disease

A chronic digestive disease where the liquid content of the stomach refluxes into the esophagus.

(GERD) with a history of erosive esophagitis.

Full Answer

What is Protonix IV used to treat?

Protonix IV (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis in adult patients.

What is the duration of Protonix treatment?

Apr 11, 2022 · Uses for Protonix IV. Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD) with a history of erosive esophagitis. GERD is a condition in which the acid in the stomach washes back up into the esophagus.

What is the dosage of Protonix IV for injection in hypersecretory conditions?

Nov 15, 2021 · Uses of Protonix I.V.: It is used to treat gastroesophageal reflux disease (GERD; acid reflux). It is used to treat syndromes caused by lots of stomach acid. It may be given to you for other reasons. Talk with the doctor. What do I need …

How do you reconstitute Protonix IV?

Apr 07, 2021 · Protonix IV (pantoprazole sodium) is a Proton Pump Inhibitor (PPI) used to treat Erosive Esophagitis associated with GERD, short-term treatment of GERD, and Zollinger-Ellison Syndrome. Side effects include unusually fast, slow or irregular heartbeat; persistent muscle spasms, seizures, persistent diarrhea, abdominal pain or cramping, fever, blood or mucus in …

Why is Protonix IV given?

Protonix IV is a prescription medicine used to treat the symptoms of Erosive Esophagitis associated with GERD, short-term treatment of GERD, and Zollinger-Ellison Syndrome. Protonix IV may be used alone or with other medications. Protonix IV belongs to a class of drugs called Proton Pump Inhibitors.

Is Protonix a short-term drug?

What Is Protonix? Protonix Delayed-Release Oral Suspension and Delayed-Release Tablets (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis in adult patients.

How long does Protonix IV last?

The recommended adult dosage of PROTONIX I.V. is 80 mg intravenously every 12 hours. The frequency of dosing can be adjusted to individual patient needs based on acid output measurements. In those patients who need a higher dosage, 80 mg intravenously every 8 hours is expected to maintain acid output below 10 mEq/h.

Can you take pantoprazole short-term?

Dosage and strength

You can buy pantoprazole 20mg tablets from pharmacies. These are suitable for the short-term treatment of heartburn and acid reflux in adults.

Why is Protonix given in the hospital?

Many patients who are admitted into hospitals are put on proton pump inhibitors (PPIs) both to prevent gastrointestinal bleeding and as heartburn/gastroesophageal reflux disease relief after discharge.Nov 29, 2015

What does Protonix help with?

This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

Can Protonix be given IV?

PROTONIX I.V. for Injection should be administered intravenously over a period of at least 2 minutes. The dosage of PROTONIX I.V. for Injection in patients with pathological hypersecretory conditions including Zollinger-Ellison Syndrome varies with individual patients.

What is Protonix drip?

What Is Protonix IV? Protonix IV (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis in adult patients.

How fast can you IV push Protonix?

Each vial will have a final concentration of 4 mg/ml. Prior to infusion, two reconstituted vials (80 mg/20 ml total) should be further admixed with 80 ml of NS, to a final pantoprazole infusion concentration of approximately 0.8 mg/ml. For the 80 mg IV bolus, give as an IV infusion over a period of 30 minutes.

How long does Protonix stay in system?

Pantoprazole is extensively metabolized in the liver through the cytochrome P-450 system, predominantly by CYP2C19 demethylation with subsequent sulfation and has a serum elimination half-life of about 1.1 hours.
...
Tables.

a	Adapted from reference 44.
b	Based on recommended dosages.

Is long term use of Protonix safe?

PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal.

How long is it safe to take pantoprazole?

Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.

What Do I Need to Tell My Doctor Before I Take Protonix I.V.?

1. If you have an allergy to pantoprazole or any other part of Protonix I.V. (pantoprazole injection). 2. If you are allergic to any drugs like thi...

What Are Some Things I Need to Know Or Do While I Take Protonix I.V.?

1. Tell all of your health care providers that you take Protonix I.V. (pantoprazole injection). This includes your doctors, nurses, pharmacists, an...

How Is This Medicine (Protonix I.V.) Best Taken?

Use Protonix I.V. (pantoprazole injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. Keep t...

What Are Some Side Effects That I Need to Call My Doctor About Right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...

What Are Some Other Side Effects of Protonix I.V.?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...

How Do I Store and/or Throw Out Protonix I.V.?

1. If you need to store Protonix I.V. (pantoprazole injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.

What is Protonix used for?

Uses of Protonix I.V.: It is used to treat gastroesophageal reflux disease ( GERD; acid reflux ). It is used to treat syndromes caused by lots of stomach acid. It may be given to you for other reasons. Talk with the doctor.

Can Protonix cause fractures?

This medicine may raise the chance of hip , spine, and wrist fractures in people with weak bones ( osteoporosis ). The chance may be higher if you take Protonix I.V. (pantoprazole injection) in high doses or for longer than a year, or if you are older than 50 years old.

Can a drug cause side effects?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache . Stomach pain or diarrhea. Upset stomach or throwing up. Gas.

What does it mean when you throw up blood?

Call your doctor if you have throat pain, chest pain, very bad belly pain, trouble swallowing, or signs of a bleeding ulcer like black, tarry, or bloody stools, throwing up blood, or throw up that looks like coffee grounds. These may be signs of a worse health problem.

What are the symptoms of an allergic reaction?

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What to do if you think you have an overdose?

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

What to do if your symptoms are not getting better?

If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.

Heartburn (Acid Reflux, GERD): Causes and Remedies

Heartburn is a symptom of acid reflux that causes chest pain when stomach acid backs up into the esophagus. Heartburn symptoms...

Heartburn: Foods to Eat, Foods to Avoid

Learn the symptoms of heartburn and which foods cause heartburn or GERD. Discover home remedies and which foods may provide...

GERD Quiz: Test Your Digestive Diseases IQ

Who is at risk for developing GERD? Are you? Take this quiz to learn what GERD is, if you're at risk, and what you can do about...

Picture of Gastroesophageal Reflux (GERD)

The stomach contents regurgitate and back up (reflux) into the esophagus The food in the stomach is partially digested by...

What is Protonix IV?

Protonix IV is a prescription medicine used to treat the symptoms of Erosive Esophagitis associated with GERD, short-term treatment of GERD, and Zollinger-Ellison Syndrome. Protonix IV may be used alone or with other medications. Protonix IV belongs to a class of drugs called Proton Pump Inhibitors. It is not known if Protonix IV is safe and ...

Can you estimate the frequency of adverse reactions to protonix?

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Is pantoprazole sodium soluble in water?

Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane.

How long does it take to take 40 mg of pantoprazole?

The recommended adult dose is 40 mg pantoprazole given once daily by intravenous infusion for 7 to 10 days. Treatment with PROTONIX® I.V. (pantoprazole sodium) for Injection should be discontinued as soon as the patient is able to receive treatment with PROTONIX Delayed-Release Tablets or Oral Suspension.

Can adverse reaction rates be directly compared to rates in clinical trials?

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

Can you take Atazanavir with nelfinavir?

Concomitant use of atazanavir or nelfinavir with proton pump inhibitors is not recommended. Coadministration of atazanavir or nelfinavir with proton pump inhibitors is expected to substantially decrease atazanavir or nelfinavir plasma concentrations and may result in a loss of therapeutic effect and development of drug resistance.

Does pantoprazole affect the absorption of drugs?

Pantoprazole causes long-lasting inhibition of gastric acid secretion, therefore pantoprazole may interfere with absorption of drugs where gastric pH is an important determinant of their bioavailability (e.g., ketoconazole, ampicillin esters, iron salts, and digoxin).

What is pantoprazole used for?

Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD) with a history of erosive esophagitis. GERD is a condition in which the acid in the stomach washes back up into the esophagus. This medicine may also be used to treat Zollinger-Ellison syndrome or other conditions (eg, cancer) in which the stomach produces too much acid.

Can medicine cause side effects?

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Can you use alcohol with a medicine?

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Can you take two different meds together?

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

How to take Protonix?

Protonix is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself. Protonix tablets are taken by mouth, with or without food. The oral granules should be taken 30 minutes before a meal.

How long does Protonix last?

Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals. Protonix is also used to treat Zollinger-Ellison syndrome ...

What are the side effects of pantoprazole?

severe stomach pain, diarrhea that is watery or bloody; sudden pain or trouble moving your hip, wrist, or back; bruising or swelling where intravenous pantoprazole was injected; kidney problems - fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;

What are the side effects of a syringe?

headache, dizziness; stomach pain, gas, nausea, vomiting, diarrhea; joint pain; or. fever, rash, or cold symptoms (most common in children). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Does Protonix help with heartburn?

Protonix is not for the immediate relief of heartburn symptoms. Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Can pantoprazole cause kidney problems?

Pantoprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine. Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it. Pantoprazole may cause new or worsening symptoms of lupus.

What does low magnesium mean?

low magnesium - dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or. new or worsening symptoms of lupus - joint pain, and a skin rash on your cheeks or arms that worsens in sunlight.