Treatment FAQ

who should not have low testosterone treatment

by Dr. Lenora Hessel Published 3 years ago Updated 2 years ago
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It is worthy to note that some people should not receive this treatment even though they have low testosterone levels. These people include; people that are allergic to prostate cancer, breast cancer, diabetes, heart diseases, liver or kidney diseases, etc. Medical vs Natural Treatment Options

Who shouldn't take testosterone replacement therapy?
  • An enlarged prostate resulting in urinary symptoms (difficulty starting a urinary stream)
  • A lump on their prostate that has not been evaluated.
  • A PSA measurement above 4.
  • Breast cancer.
  • An elevated hematocrit level (higher-than-normal number of red blood cells)
Apr 10, 2018

Full Answer

Do I need to have low testosterone to go on testosterone therapy?

In most cases, men need to have both low levels of testosterone in their blood and several symptoms of low testosterone to go on therapy. It is possible to have low levels and not experience symptoms.

What is the treatment for low testosterone in men?

Hormone Replacement Therapy. When the cause of low testosterone is testicular failure, testosterone replacement therapy (TRT) can help reestablish sexual function, inhibit bone loss, and rebuild muscle strength, while also boosting sex drive, energy, and confidence.

Why not take testosterone directly?

Why not take testosterone directly?” The short answer is: testosterone replacement therapy (TRT) can be extremely hazardous to your health. It’s much safer to attain higher T levels by taking nutrients proven to boost testosterone production naturally within the human body than to consume the hormone

What causes low testosterone levels?

Some of these signs and symptoms can be caused by various underlying factors, including medication side effects, obstructive sleep apnea, thyroid problems, diabetes and depression. It's also possible that these conditions may be the cause of low testosterone levels, and treatment of these problems may cause testosterone levels to rise.

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Who should not receive testosterone?

Who Shouldn't Take Testosterone Replacement Therapy? Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure.

What are the disadvantages of testosterone therapy?

Testosterone therapy has various risks, including: Worsening sleep apnea — a potentially serious sleep disorder in which breathing repeatedly stops and starts. Causing acne or other skin reactions. Stimulating noncancerous growth of the prostate (benign prostatic hyperplasia) and growth of existing prostate cancer.

What are the cons of low testosterone?

Decreases in testosterone can lead to physical changes including the following:increased body fat.decreased strength/mass of muscles.fragile bones.decreased body hair.swelling/tenderness in the breast tissue.hot flashes.increased fatigue.effects on cholesterol metabolism.

What happens if low testosterone goes untreated?

Living with a testosterone deficiency long-term will increase your likelihood of developing age-related diseases, including osteoporosis and heart disease, among others.

Should a 50 year old man take testosterone?

Most older men don't need testosterone replacement, new guidelines say. (Reuters Health) - Older men whose testosterone levels have dropped over the years should only be given testosterone replacement to treat sexual dysfunction, according to new guidelines from the American College of Physicians released on Monday.

What are the negative effects of testosterone?

Misuse of testosterone can cause dangerous or irreversible effects, such as enlarged breasts, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence.

How does low testosterone make you feel?

A decrease in energy levels Low testosterone can lead to reduced levels of energy and fatigue. A person may feel tired, even after adequate rest, or develop a diminished interest in exercise or movement.

Is low testosterone life threatening?

One study in the Journal of Clinical Endocrinology and Metabolism also linked low testosterone to a higher risk of death from heart disease and other causes.

At what level should low testosterone be treated?

The general target level for testosterone ranges from 350 to 750 ng/dL, which is roughly the range for healthy, androgen-sufficient adult men. Testosterone levels should be monitored 3 to 6 months after initiation of treatment.

Can you live a long life with low testosterone?

Researchers found men with the lowest testosterone levels had the highest mortality rate, followed by men with the highest testosterone levels. Overall, men with circulating testosterone levels between 9.8 to 15.8 nmol/L range tended to live the longest.

Can low testosterone cause early death?

Summary: Low testosterone levels seem to be linked to a heightened risk of premature death from heart disease and all causes, new research suggests. Low testosterone levels seem to be linked to a heightened risk of premature death from heart disease and all causes, suggests research published online in Heart.

Can low testosterone cause heart attacks?

There was little evidence of a link between low testosterone and atherosclerosis, the hardening and narrowing of the arteries that can cause heart attack and stroke. There was no connection between testosterone levels and heart attack risk.

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Why is testosterone low in older men?

For older men, it's important to determine if a low testosterone level is due to normal aging or if it is due to a disease (hypogonadism). Hypogonadism hampers the ability to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. Testosterone replacement therapy, in the ...

What is the role of testosterone in the development of a man?

The male hormone testosterone plays an important role in the development and maintenance of typical masculine physical characteristics, such as muscle mass and strength, and growth of facial and body hair.

What causes a person to stop breathing?

Worsening sleep apnea — a potentially serious sleep disorder in which breathing repeatedly stops and starts. Causing acne or other skin reactions. Stimulating noncancerous growth of the prostate (benign prostatic hyperplasia) and growth of existing prostate cancer. Enlarging breasts.

What test is used to diagnose low testosterone?

A blood test is used to diagnose a low testosterone level.

What happens if you have too much red blood cell production?

Stimulating too much red blood cell production, which contributes to the increased risk of forming a blood clot. A clot could break loose, travel through your bloodstream and lodge in your lungs, blocking blood flow (pulmonary embolism).

Is testosterone therapy good for age?

By Mayo Clinic Staff. As you age, testosterone therapy might sound promising. But there are a lot of misconceptions about what the treatment can and can't do for you. Testosterone therapy might seem like the ultimate anti-aging formula. Yet the health benefits of testosterone therapy for age-related decline in testosterone aren' t clear.

When does testosterone peak?

Testosterone levels generally peak during adolescence and early adulthood. As you age, your testosterone level gradually declines — typically about 1% a year after age 30 or 40. For older men, it's important to determine if a low testosterone level is due to normal aging or if it is due to a disease (hypogonadism).

How much testosterone is normal?

Normal levels of testosterone range from about 300 to 900 nanograms per deciliter (ng/dL), and there's little to suggest that men whose levels fall within that range would benefit from therapy, says urologist Michael Eisenberg, MD, director of male reproductive medicine and surgery at Stanford Hospital and Clinics in Palo Alto, Calif.

Does testosterone cause heart problems?

Again, it's not clear if low testosterone levels actually cause heart problems. Both Eisenberg and Morgentaler say that testosterone therapy can dramatically affect a man's quality of life. Besides its sexual benefits, TRT can improve a man's mood and energy level while reducing irritability and anger.

Does testosterone affect heart health?

Testosterone is also tied to heart health, says Eisenberg, who discloses that he has received a grant from Endo Pharmaceuticals to study the association between testosterone and health. "Lower testosterone levels have been linked to higher risk of cardiovascular problems," Eisenberg says.

How long after taking a nasal spray can you get in contact with a woman?

Still, as a precaution, he advises men to avoid skin -to-skin contact with women, children, or pets for the first two to four hours after applying medication. A nasal gel is now available that eliminates the risk of exposure to others.

Does testosterone affect life expectancy?

Testosterone may also play a role in how long men live. Recent studies, Morgentaler says, show a link between low testosterone and shorter life expectancy. "Men with low T die sooner than men with normal levels of testosterone," he says. It's not clear if low testosterone, by itself, makes earlier death more likely.

Can a man with low testosterone stay on it?

To continue to benefit, a man with low testosterone must remain on it. However, says Eisenberg, we don’t know a lot about its long-term safety.

Can you use testosterone gel on a woman?

Men who use a testosterone gel should wash their hands thoroughly after applying a dose and make sure that no one else touches the spots where they medicate. If a woman or child comes into contact with testosterone gels, it can cause side effects in them, including hair growth and premature puberty.

What is testosterone replacement therapy?

Testosterone replacement therapy is the intake of testosterone directly into your body where it then enters the bloodstream. The forms of TRT include injections, patches, gels, and pills. TRT was first made available as a patch, but it caused skin irritation in as many as one out of four men who wore the patches.

How to increase testosterone levels naturally?

The solution: Make some nutritional, exercise, and other lifestyle changes that can elevate your testosterone levels naturally. Take healthy nutrients – herbs, amino acids, minerals, vitamins – that trigger your body to produce new testosterone as nature intended.

How old are men with low testosterone?

A study published in the Journal of the American Medical Association (JAMA) examined 1,223 men with low testosterone levels who were about 60 years old. The JAMA study found that those men in the group who took testosterone replacement therapy had a 30% increase in risk of stroke and heart attack vs. men in the group who did not do TRT.

Does TRT increase testosterone?

But the prognosis for using TRT to boost declining testosterone levels gets worse. To begin with, testosterone therapy can elevate your red blood cell count. This in turn can thicken the blood, putting you at greater risk for stroke and heart attack. A study published in the Journal of the American Medical Association (JAMA) examined 1,223 men with low testosterone levels who were about 60 years old.

Can testosterone be taken as a pill?

And, starting at around age 30, your testosterone levels decline with each passing year. Yet reversing the decline by taking testosterone directly – either ingesting it as a pill, through injection, or by applying a gel or patch – is downright dangerous, risking liver toxicity, stroke, heart attack, and other ills.

Does Striant cause gum irritation?

While it is more effective than patches at boosting testosterone levels, Striant can cause gum or mouth irritation, pain, and tenderness.

Is testosterone gel discontinued?

Another study, published in the New England Journal of American, examined the effect of testosterone gel in men 65 and older. It was discontinued when participants experienced cardiac, respiratory, and skin problems. Many did, however, experience an increase in muscle strength before the study was halted.

Does TRT cure low testosterone?

Indefinitely. TRT does not cure low testosterone, so your symptoms may return if you stop taking it.

Is testosterone replacement therapy safe?

Medically Reviewed by Carol DerSarkissian, MD on August 07, 2019. If you've been diagnosed with an abnormally low T, testosterone replacement therapy (TRT) offers a lot of benefits. But there are risks, too.

Can you have TRT if you have breast cancer?

Guidelines from the Endocrine Society say you should not have TRT if you have prostate cancer or breast cancer. But some studies suggest that men who have been successfully treated for prostate cancer may be candidates for TRT as long as they are closely watched for signs of disease.

Does TRT help with ED?

If you have low testosterone, TRT may help restore your ability to have healthy erections and can boost your sex drive. But ED has many other possible causes. Low testosterone may not be the whole story behind your ED. Talk to your doctor to determine what's at the root of your erection problems.

Why is testosterone low?

Low testosterone can be caused by a problem with the testicles themselves, or it can be caused by a problem with the pituitary or the hypothalamus. Pinpointing the cause will determine how the condition is treated. The condition can occur in babies (due to undescended testes) and boys ...

What does low testosterone do to a man?

Low testosterone, also called hypogonadism, can cause a man to lose his fertility, body mass, self-confidence, and energy. A urologist can help diagnose the condition, and explain the treatment options for low testosterone. Testosterone is a hormone produced primarily by the testes and its levels are controlled by a feedback loop between ...

How to restore fertility after low testosterone?

If the cause of low testosterone stems from issues with the pituitary gland, it may be possible to restore fertility through the use of pituitary hormones. If the pituitary gland is simply underactive, the hormones would reinstate the pituitary-hypothalamus-testes feedback loop and revive sperm production.

Which gland controls testosterone?

Testosterone is a hormone produced primarily by the testes and its levels are controlled by a feedback loop between the hypothalamus and pituitary gland . All three (testes, hypothalamus, and pituitary) must be working properly to sustain the appropriate hormone levels.

What is the best treatment for a sex problem?

Beta blockers, which decrease testosterone and impede arousal by interfering with nerve impulses. Alternative treatments include antihypertensives, such as calcium-channel blockers, that don't interfere with sexual function.

How to treat melatonin in the night?

Alternative treatments include changes to diet and sleep habits, or trying melatonin at night and during the day, consuming several glasses of water with one tablespoon of apple-cider vinegar and one tablespoon of honey mixed in.

Where to apply testosterone patch?

Patch: This hormone patch is applied to the back, upper arm, thigh, or abdomen every night. Gel: A gel containing testosterone is rubbed into the skin. Skin-to-skin contact with anyone should be avoided until the gel is dry. Oral: In this approach, the testosterone is applied where the upper lip and gum line connect.

How to get rid of low T?

Men who carry excess fat also can have too much estrogen, since this hormone is produced in fat cells. An imbalance in estrogen and testosterone levels is a recipe for classic low-T symptoms. Lose the excess weight (diet and exercise will definitely help) and then maintain your new, healthy weight.

How to boost nitric oxide?

Take supplements that can help boost nitric oxide and promote better energy and sexual health . There are many herbs like Tribulus terrestris that have been shown in the studies to help promote strength, libido and peak performance. These ingredients can work together to promote natural free testosterone levels, and boost sexual health.

Why do men have low T?

But the other side of the coin is more likely the truth: men have low T and/or these classic symptoms because they are overweight, don’t get enough sleep, eat a poor diet, consume too much alcohol, are sedentary, and don’t manage chronic stress. In other words:

Why is my T low?

Stress management. Stress can cause low T because the stress hormone, cortisol, blocks production of testosterone. Daily management of stress using meditation, yoga, tai chi, progressive relaxation, or whatever works for you, is highly recommended.

Does testosterone help with weight gain?

The biggest complaints men have that often lead them to consider testosterone therapy are weight gain, lack of energy, low libido, depression, and lack of muscle tone. They have been convinced that taking testosterone therapy will solve their problems.

Does testosterone decrease with age?

While it is true that testosterone levels decline somewhat with age, lifestyle changes and not testosterone therapy is the way to tackle the classic symptoms.

Does lifestyle affect testosterone?

The following lifestyle factors can have a hugely positive effect on your testosterone levels. Take a look to see which ones you can change to help improve your testosterone levels and eliminate your symptoms?

What to do after starting testosterone?

After starting therapy, follow-up with your physician periodically to have testosterone checks and other lab tests to make sure the therapy is not causing any problems with your prostate or blood chemistry.

How to test for testosterone?

Get an accurate assessment 1 Inaccurate or misinterpreted test results can either falsely diagnose or miss a case of testosterone deficiency. Your testosterone level should be measured between 7 am and 10 am, when it's at its peak. Confirm a low reading with a second test on a different day. It may require multiple measurements and careful interpretation to establish bioavailable testosterone, or the amount of the hormone that is able to have effects on the body. Consider getting a second opinion from an endocrinologist. 2 After starting therapy, follow-up with your physician periodically to have testosterone checks and other lab tests to make sure the therapy is not causing any problems with your prostate or blood chemistry.

What is testosterone gel?

Millions of American men use a prescription testosterone injection or gel as forms of testosterone replacement therapy (often referred to as TRT therapy) to restore normal levels of the manly hormone. The ongoing pharmaceutical marketing blitz promises that low T treatment can make men feel more alert, energetic, mentally sharp, ...

Can hormone replacement therapy help with low testosterone?

For male patients with low blood testosterone levels, the benefits of hormone replacement therapy for men usually outweigh potential risks. However, for most other men it's a shared decision with your doctor. It offers men who feel lousy a chance to feel better, but that quick fix could distract attention from unknown long-term hazards. "I can't tell you for certain that this raises your personal risk of heart problems and prostate cancer, or that it doesn't," Dr. Pallais says.

Can testosterone help prostate cancer?

Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. As with the hypothetical cardiac risks, the evidence is mixed. But because prostate cancer is so common, doctors tend to be leery of prescribing testosterone to men who may be at risk.

Does testosterone cause heart problems?

Men on long-term using forms of testosterone therapy long term appear to have a higher risk of cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. For example, in 2010, researchers halted the Testosterone in Older Men study when early results showed that men on testosterone replacement therapy had noticeably more heart problems. "In older men, theoretical cardiac side effects become a little more immediate," Dr. Pallais says.

Can low T cause erectile dysfunction?

If erectile dysfunction has caused you to suspect " low T" as the culprit, consider that cardiovascular disease can also cause erectile dysfunction.

Why won't my doctor treat my testosterone?

The other possible explanation to my doctor won’t treat my low testosterone levels is that their doctors feel that they are not exhibiting the symptoms that are commonly associated with Low T. Many doctors believe that the use of a treatment program is not warranted unless a patient has fully developed all of the chronic symptoms ...

Why do bodybuilders use testosterone?

Anyone who follows professional sports has undoubtedly heard about this, and it is well known that many bodybuilders use testosterone to pump up their muscles and tone their physiques. Doctors hear about these abuses as well and it’s possible that there are instances when it’s a factor in why my doctor won’t treat my low testosterone levels.

Can Nexel treat low testosterone?

At Nexel Medical, our Low T specialists are sometimes contacted by men who say something along the lines of my doctor won’t treat my low testosterone levels, and they seem unsure of the reason. Either they didn’t pursue the matter with their primary care providers any further or their providers told them they would have to see a medical specialist if they wanted to pursue treatment for their testosterone deficiency. In any event, they were apparently not given any detailed reasons for their doctors declining to provide them with a Low T treatment program.

Is low T therapy illegal?

Actually, it is the illegal use and/ or abuse of bio-identical testosterone treatments that accounts for the majority of adverse effects that some men experience. It is not a secret that ...

Is a low T level a low risk?

It is a form of treatment that has been in medical use for many decades and it has proven to be both highly effective and statistically very low risk as a means for restoring a man’s Low T levels to the normal range and providing him with relief from his troublesome symptoms.

Is TRT safe for men?

Despite all of the supporting evidence for using TRT, some doctors still feel that not enough is known about the potential risks that its extended use could represent. Yet in over its half-century of medical use, thousands of men have used this treatment long-term without experiencing any related health complications or risks. The incidence of side effects experienced by Low T therapy users has also remained statistically very low throughout its history of medical usage. Actually, it is the illegal use and/or abuse of bio-identical testosterone treatments that accounts for the majority of adverse effects that some men experience.

What is the term for partial androgen decline in the ageing male?

Partial androgen decline in the ageing male (PADAM)

What causes hypogonadism in the testicles?

Primary hypogonadism is caused by testicular failure and is characterised by low serum testosterone and high LH and FSH concentrations. For this reason, primary hypogonadism is also known as hypergonadotropic hypogonadism. Primary hypogonadism can result from testicular injury, tumour, or infection; genetic defects affecting testicular development (e.g. Klinefelter syndrome), as well as chemotherapy, radiation treatment or alcohol abuse (3,16).

What are the symptoms of hypogonadism?

The main symptoms of hypogonadism are reduced libido/erectile dysfunction, reduced muscle mass and strength, increased adiposity, osteoporosis/low bone mass, depressed mood and fatigue. Diagnosis of the condition requires the presence of low serum testosterone levels and the presence of hypogonadal symptoms. There are a number of formulations available for testosterone therapy including intramuscular injections, transdermal patches, transdermal gels, buccal patches and subcutaneous pellets. These are efficacious in establishing eugonadal testosterone levels in the blood and relieving symptoms. Restoration of testosterone levels to the normal range improves libido, sexual function, and mood; reduces fat body mass; increases lean body mass; and improves bone mineral density. Testosterone treatment is contraindicated in subjects with prostate cancer or benign prostate hyperplasia and risks of treatment are perceived to be high by many physicians. These risks, however, are often exaggerated and should not outweigh the benefits of testosterone treatment.

How many people will have hypogonadism by 2025?

As the number of individuals aged 65 years and over in the US population is projected to rise from approximately 40 million (13.0%) in 2010 to approximately 60 million (17.9% ) in 2025, the number of men, who presently comprise approximately 43% of this population, that are hypogonadal will also increase (1). As a result, physicians will be increasingly likely to encounter men with the symptoms of hypogonadism in the clinic.

What is the purpose of a review of hypogonadism?

The purpose of this review is to summarise the current understanding of male hypogonadism, with particular reference to the needs of the primary care physician. A key consideration for any physician is to understand the clinical significance of low testosterone levels and how hypogonadal men are likely to benefit from testosterone replacement therapy. It is also important to have a good understanding of the contraindications and risks associated with the therapy as well as the necessary treatment monitoring required.

How is testosterone converted to DHT?

Testosterone is converted to dihydrotestosterone (DHT) by 5α-reductase enzymes or to estradiol by aromatase in target cells . Testosterone and DHT both bind to the androgen receptor where they exert their biological effects. Approximately 20% of the DHT in the circulation is produced directly by testicular secretion, with the remaining 80% being derived from conversion from testosterone in the peripheral tissues (10).

How much testosterone is secreted in the pituitary?

A total of approximately 7 mg of testosterone is secreted each day (8), although in older men the rate decreases (9).

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