Treatment FAQ

what is y-90 treatment

by Audrey Kub Published 2 years ago Updated 2 years ago
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Y-90 therapy, also known as selective internal radiation therapy or SIRT, is a minimally invasive, image-guided approach treating malignant lesions in the liver. The procedure uses a catheter to deliver tiny radioactive beads into the blood vessels that lead directly to the tumor.

What is y90 used for in radiation therapy?

Y-90 radiotherapy is also a minimally invasive treatment. This means that only small medical tools are used and your body is not opened up. This means your body will recover more quickly than it would after regular surgery. What beads are used in Y-90 radiotherapy? The beads used in Y-90 radiotherapy are made of either plastic or glass.

What is y90 for liver cancer?

What is Radioembolization (Y-90 SIRT)? Radioembolization, also called Y-90 Selective Internal Radiation Therapy (SIRT), is a minimally invasive liver-directed therapy for liver cancer that either arises from the liver (primary liver cancer or hepatocellular carcinoma) or has metastasized to the liver from other organs most commonly the colon or ...

What is yy-90 SIRT used to treat?

What is Y-90 and is it safe?

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Does Y90 cure cancer?

The treatment is not a cure for cancer in the liver, but it has been shown to prolong lives for months or years and to greatly improve the quality of life of cancer patients. Patients experience few, if any, side effects from Y90 treatment, which is performed in an outpatient setting.

How long does a Y90 procedure last?

This procedure takes about 1 hour. We often treat only half of the liver in Step 2. If you need a second Y-90 infusion to treat other parts of your liver, you will have another Y-90 infusion session 4 to 6 weeks after Step 2.

How effective is Y90 treatment?

Radioembolization is a treatment, not a cure. Approximately 70 to 95 percent of the patients will see improvement in the liver and, depending on the type of liver cancer, it may improve survival rates.

How many Y90 treatments can you have?

Patients are typically limited to two treatments, although doctors can take another approach — only with concentrated chemotherapy and larger particles — once radiation limits are reached.Jan 27, 2017

Are you radioactive after Y-90 treatment?

The Y90 has a half-life of 64.2 hours. This means that it will be non-radioactive in about a month's time.Oct 31, 2019

How much does Y-90 treatment cost?

The primary outcome was the overall difference in cost between Y-90 vs TACE for treatment of hepatocellular carcinoma at Einstein Medical Center. The price of a Y-90 ranges from $30,000 to $35,000 with an average of $32,500.

How long is Y90 mapping?

The mapping procedure will take about 2-4 hours. Dr. Christenson will place a small plastic tube (called a catheter) into one of the vessels in your groin and direct the catheter to the blood vessels in your liver.

Can radiation shrink liver tumors?

Radiation therapy can shrink or kill tumor cells. At Memorial Sloan Kettering, we may recommend this approach if you have a primary liver tumor that can't be removed with surgery. It can be used alone or in combination with chemotherapy or other treatments.

Is Y90 a brachytherapy?

The Yttrium-90 irradiates from within and can be viewed as "internal" radiation or "brachytherapy." Radioembolization is a palliative, not a curative, treatment. Patients may benefit by extending their lives and improving their quality of life.

What is the difference between TACE and Y90?

Y90 is better tolerated with a smaller side effect profile when compared to TACE therapy. However, Y90 is an expensive treatment option, which isn't feasible for certain patient populations, such as those on Medicaid. Y90 is a very well-tolerated procedure.

Is microwave an ablation?

Microwave ablation (MWA) is a minimally-invasive treatment for cancer. MWA uses ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) to guide placement of a needle-like probe into a tumor. MWA uses microwaves to heat and destroy the tumor. Doctors use MWA for the same indications as RFA.

What is Y90 treatment?

In contrast to most nuclear medicine applications, Y90 is therapeutic and designed to treat rather than simply diagnose. It is estimated that 75% to 95% of patients see improvement from treatment, potentially extending their lives or improving survival rates. In this post we’ll take a look at Y90, what it is, and how it works.

What is Y90 therapy?

When is Y90 therapy indicated? Hepatic (liver) tumors (lesions or masses) may originate as a primary cancer of the liver such as hepatocellular cancer (90% of primary liver cancers) or may be another form of cancer that has metastasized to the region . There are many treatment options available for hepatic lesions.

How to avoid radiation?

As a precaution, the following is recommended: 1 Contact with others is limited over the week as the radiation diminishes 2 Patients shouldn’t sleep in the same bed as a partner over that week 3 Patients should avoid public transport that requires them to sit next to another person for more than two hours 4 Patients should avoid close contact with children or pregnant women.

What is Y90 used for?

Yttrium-90 (Y90) is a commonly used isotope within the nuclear medicine and radiation oncology communities for radiation therapy. When used for the treatment, Y90 is relied upon to provide a prescribed amount of radiation to a targeted area. Y90 is most commonly used during a radioembolization therapy, an internal radiation therapy.

Is radioembolization painful?

The radioembolization procedure is generally painless for patients. For a small number of patients, ulcers may develop in the stomach or duodenum – these are treated as any other type of ulcer.

What is the Ergo camera?

A camera such as the Ergo with its digital technology captures all data without any holes and provides a more accurate picture. After the mapping process is complete, the images are further analyzed by the medical team and then an exact amount of Y90 is prescribed to treat the lesion.

Does Y90 help with liver cancer?

Radioembolization with Y90 utilizes nuclear medicine to treat hepatic lesions. Most patients will see some improvement in their liver and it may improve survival and life expectancy rates, depending on the type of cancer. This treatment is not recommended in cases of severe kidney or liver dysfunction, abnormal blood clotting or blockages ...

What is Y-90 SIRT?

What is Radioembolization (Y-90 SIRT)? Radioembolization, also called Y-90 Selective Internal Radiation Therapy (SIRT), is a minimally invasive liver-directed therapy for liver cancer that either arises from the liver (primary liver cancer or hepatocellular carcinoma) or has metastasized to the liver from other organs most commonly ...

How long after SIRT procedure can you return home?

S ince you will have received a radioactive treatment, there are some simple precautions that need to be taken during the first 24 hours following the SIRT procedure. Very importantly, there is no danger in returning home immediately after the procedure is completed.

What is the liver's blood supply?

The liver is unique because it has two blood supplies—the hepatic artery and the portal vein. The normal liver receives about 75 percent of its blood supply through the portal vein and only 25 percent through the hepatic artery. But when a tumor grows in the liver, it receives almost all of its blood supply from the hepatic artery. ...

How long does it take for a tumor to decay?

The whole procedure may take around 60–90 minutes.

What are the benefits of a liver transplant?

Other benefits include: Delays the time to tumor progression (the time it takes for a tumor to regrow) Extends overall survival rate. Potentially downsizes or downstages tumors for liver resection, ablation, or transplantation giving patients a genuine chance for rehabilitation. Provides palliation of symptoms.

Can liver cancer be treated with radiation?

This typically happens after one treatment but treatments can be repeated if necessary to achieve complete tumor destruction. The targeted nature and high level of precision of this therapy enable doctors to deliver more radiation to the liver tumors than would be possible using conventional external beam radiotherapy.

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What Can I Expect from The Procedure?

  • One to two weeks before the delivery of the Y90 to the liver tumors, you will have appointments with your interventional radiologist, who will test your blood and perform an angiogram—an imaging procedure in which dye is injected into the bloodstream and X-ray images are taken. Thi…
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Are There Any Risks?

  • The procedure is relatively safe when performed by an experienced interventional radiologist. Major complications include: 1. Post-embolization syndrome consisting of consisting of pain, nausea, and low-grade fever 2. Irritation of the stomach or small intestine, including ulcers 3. Fatigue, which is typically significant and can last from a few days to a few weeks
See more on columbiaradiology.org

After The Procedure

  • Most patients are scheduled early in the day in our outpatient office and recover in their own private room, going home in the afternoon. Imaging is performed on the day of the procedure to confirm the location within the liver where the radiation particles have been deposited. For the next week you may experience a low-grade fever, lethargy, or fatigue. Pain is not a common sid…
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Follow Up

  • We will schedule a follow up appointment with you about two weeks after the procedure. Chemotherapy can typically be restarted one to two weeks after the procedure. Follow up imaging, such as CT, MRI, or PET CT, is usually performed approximately eight weeks after the procedure.
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What Is Y90?

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Yttrium-90 (Y90) is a commonly used isotope within the nuclear medicine and radiation oncology communities for radiation therapy. When used for the treatment, Y90 is relied upon to provide a prescribed amount of radiation to a targeted area. Y90 is most commonly used during a radioembolization therapy, a…
See more on digirad.com

When Is Y90 Therapy Indicated?

  • Hepatic (liver) tumors (lesions or masses) may originate as a primary cancer of the liver such as hepatocellular cancer (90% of primary liver cancers) or may be another form of cancer that has metastasized to the region. There are many treatment options available for hepatic lesions. The choice for treatment is generally based on how they present, physician preference and treatmen…
See more on digirad.com

Y90 Mapping and Its Role with Radioembolization Therapy

  • There is a great deal of planning prior to performing a Y90 radioembolization. Here are a few steps: 1. The first step in the process is referred to as the “mapping”. The mapping process involves a very similar process to the radioembolization treatment itself; the patient is brought into interventional radiology and the vasculature of the liver tumor is examined. During this time…
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Patient Precautions and Side-Effects

  • The radioembolization procedure is generally painless for patients. For a small number of patients, ulcers may develop in the stomach or duodenum – these are treated as any other type of ulcer. Post-embolization syndrome (PES) is a side effect that is experienced by a few patients. This consists of vomiting, nausea, fever and pain, usually within the first 72 hours after treatmen…
See more on digirad.com

Final Thoughts

  • Radioembolization with Y90 utilizes nuclear medicine to treat hepatic lesions. Most patients will see some improvement in their liver and it may improve survival and life expectancy rates, depending on the type of cancer. This treatment is not recommended in cases of severe kidney or liver dysfunction, abnormal blood clotting or blockages of the bile ducts. Radioembolization ma…
See more on digirad.com

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