Table 1
| Age (years) | Lower assessment threshold | Upper assessment threshold | Intervention threshold # |
| 40 | 2.4 | 6.6 | 5.5 |
| 45 | 2.7 | 7.3 | 6.1 |
| 50 | 3.1 | 8.1 | 6.7 |
| 55 | 3.5 | 9.1 | 7.5 |
When to treat based on Frax score?
· A FRAX score of more than 5 percent for a hip fracture at age 70 and beyond means you should consider treatment along with lifestyle changes A lower FRAX score but at a younger age, may also
What Frax score to treat?
- Prescence of a hip or vertebral (spine) fracture
- BMD T Score <-2.5 at the hip or spine (osteoporosis)
- BMD T Score between -1.0 and -2.5 (osteopenia)
- BMD T score between -1.0 and -2.5 (osteoporosis) at the hip or spine and a 10 year FRAX probability of a hip fracture >3% or 10 year probability of a ...
What is considered a high Frax score?
Treatment options for high FRAX score
- Lifestyle changes. Some FRAX scores indicate that lifestyle changes should be sufficient to manage the risk of fractures.
- Preventing falls. Falls account for nearly 90% of fractures in people with osteoporosis. ...
- Medication. A high FRAX score indicates that the person might need medical treatment in addition to making these lifestyle changes.
When to treat Frax score?
· Treatment is recommended in women with a T-score of –2,5 or less, For women with a T-score between –1,0 and –2,5, FRAX can assist in making an informed deci-sion about treatment
What is a significant FRAX score?
greater than -1: normal. -1 to -2.5: low bone mass (called osteopenia, a potential precursor condition to osteoporosis) less than -2.5: typically indicates osteoporosis.
What is a high risk FRAX score?
In the 2020 update of the Endocrine Society's clinical practice guideline for the pharmacological management of osteoporosis in postmenopausal women, very high risk is defined as including severe or multiple vertebral fractures in addition to a BMD T-score of ≤−2.5 at the hip or spine.
What is the threshold for osteoporosis?
The diagnostic threshold for osteoporosis, a bone mineral density (BMD) T-score ≤ −2.5, signals an increased risk for fracture. However, most fragility fractures arise among the majority of women with 'osteopenia' or 'normal' BMD.
How accurate is FRAX score?
Results: Seven studies (n=57,027) were analyzed to assess diagnostic accuracy of FRAX in predicting MOF, using 20% as the 10-year fracture risk threshold for intervention, the mean sensitivity, specificity, and diagnostic odds ratio (DOR) along with their 95% confidence intervals (CI) were 10.25% (3.76%-25.06%), 97.02% ...
What does FRAX 10-year probability mean?
A FRAX score estimates the probability of a fracture within the next 10 years. The output is a percentage, and higher values indicate a greater risk of fracture.
What percentage is considered high risk for fracture?
Introduction: We determined the agreement between a FRAX designation of high risk of fracture [defined as 10-year major osteoporotic fracture probability (≥ 20%) or hip fracture probability (≥ 3%)] and the WHO categorizations of bone mineral density according to T-score.
When do you treat based on FRAX score?
The current National Osteoporosis Foundation Guide recommends treating patients with FRAX 10-year risk scores of > or = 3% for hip fracture or > or = 20% for major osteoporotic fracture, to reduce their fracture risk.
What is fracture threshold?
The fracture threshold, defined as the 90th centile of spinal BMD for women with osteoporosis, was 0.81 g/cm2 at the lumbar spine and 0.656 g/cm2 at the femoral neck. Five per cent of normal women aged 40-49 years, 20% aged 50-59 years, and 45% aged 60-69 years had a BMD below this threshold.
What is meant by the fracture threshold?
Bone physiology A theoretical cancellous bone density below which osteoporosis-related fractures occur.
What is FRAX 10 year fracture risk?
The Fracture Risk Assessment Tool, or FRAX, is a free online tool that estimates your risk of having a hip or other major fracture in the next 10 years, especially if you have osteoporosis. The other major fractures are your spine, forearm, and shoulder.
When can you not report a FRAX?
In the United States, the National Osteoporosis Foundation recommends using FRAX to calculate fracture risk for patients who have T-scores between −1.0 and −2.5 in the spine, femoral neck, or total hip region. FRAX should not be used for patients who have already received pharmacologic treatment for osteoporosis.
What does moderate risk for fracture mean?
Moderate risk: This group requires a careful evaluation to identify vertebral fractures (e.g., spine x-rays) or additional clinical risk factors which may contribute to a decision to offer pharmacologic therapy; Low risk: These individuals usually do not require pharmacologic therapy.
What is considered high risk for fracture in osteoporosis?
Treatment of osteoporosis should be considered for patients with low bone mineral density and a ten-year risk of hip fracture of ≥3% or a ≥20% ten-year risk of a major osteoporosis-related fracture, as assessed with FRAX.
What is a severe osteoporosis T-score?
A T-score between −1 and −2.5 indicates that you have low bone mass, although not low enough to be diagnosed with osteoporosis. A T-score of −2.5 or lower indicates that you have osteoporosis. The greater the negative number, the more severe the osteoporosis.
What is major osteoporotic fracture percentage?
Conclusions—Mean hip and major osteoporotic fracture probabilities were 0.5% and 5.3%, respectively, for adults aged 40 and over. Among adults aged 50 and over, mean hip and major osteoporotic fracture probabilities were 0.9% (19% with elevated values) and 7.4% (8% with elevated values), respectively.
What is considered a major fracture?
They are cracks and breaks that are contained within the skin. They are best determined through x-ray scans. Closes fractures, on the other hand, can be compound and complex. The fracture is significant enough to have broken the skin. Displaced and undisplaced fractures.
How to lower your FRAX score?
You can lower your score and your risk right away by quitting cigarettes and cutting back on your alcohol consumption. Getting more exercise, including weight-bearing activities, is helpful too.
What is the FRAX score?
Your FRAX score is your risk of having an osteoporosis-related fracture in the next 10 years. The formula for measuring your risk uses factors such as:
Why is my FRAX score higher?
Your FRAX score will be higher if you’ve had a fracture that occurred spontaneously. It will also be higher if you’ve broken a bone caused by trauma that would not usually cause a fracture in a healthy person. Parent fractured hip. If your mother or father had a hip fracture, your risk of a similar injury is higher.
What to do if your risk of osteoporotic fracture is high?
If it looks like your risk of an osteoporotic fracture is high in the next few years, talk with your doctor about medications, supplements, lifestyle changes, and anything else you can do to reduce your risk and protect yourself from a potentially life-altering fracture. Last medically reviewed on December 8, 2017.
What does a FRAX score mean?
A FRAX score indicates the risk of a fracture in a person with osteoporosis. Doctors can use it to determine the best measures to prevent fractures and treat the condition. In this article, we look at what a FRAX score is, the results, and when to see a doctor.
How does a frax score affect osteoporosis?
By weakening the bones, osteoporosis increases the risk of fractures. A FRAX score can help doctors identify people with a high risk of fractures who may need additional support. The tool consists of questions relating to 12 factors that can increase the risk of fractures. These factors are: