Treatment FAQ

what is the treatment for ?epi

by Dr. Candice Quigley Sr. Published 1 year ago Updated 1 year ago
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Apart from a healthy diet, the main treatment for EPI is pancreatic enzyme replacement therapy (PERT). You take prescription pills that replace the enzymes your pancreas isn't making. These enzymes break down your food so you can more easily digest and absorb it. You have to take them during your meals.

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  • Take digestive enzymes at the beginning of your meal or snack, and the right amount of them. “Work with your oncologist and/or dietitian .” Marie Durbin
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How to treat epi naturally?

• The symptoms of EPI can be a lot like other medical conditions that affect the stomach and bowels.1-4,7-11This can sometimes make EPI hard to diagnose. That’s why it’s important to be open and honest with your doctor about all of your stomach and bowel problems • Tell your doctor about:

Why is epi hard to diagnose?

While there’s no cure for EPI, your doctor will work with you to find treatments that can ease your symptoms, treat any underlying conditions, and, ultimately, improve your quality of life. Here are some medications that can help in treating and managing EPI:

Can epi be cured?

Your doctor may start you on a prescription treatment called pancreatic enzyme replacement therapy, or PERT. PERTs are the main treatment for EPI—they replace the digestive enzymes that your pancreas isn’t producing anymore. When taken with food, PERTs help break down the nutrients in food.

How do you treat epi?

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What foods should you avoid with EPI?

Off the EPI Menu: Foods to Avoid In general, try to limit the amount of fat you eat — especially the saturated fats in animal-based foods, such as butter, cream, fatty cuts of red meat, organ meat, and poultry skin.

Will EPI go away on its own?

The pancreas works normally, but because of inflammation and damage to the intestines, it may not secrete enzymes in the way it should. If you switch to a gluten-free diet, however, EPI resulting from celiac disease usually will go away.

Is EPI serious?

Without treatment, EPI can make you malnourished -- you won't get enough important vitamins and nutrients from your diet -- and it can lead to other serious conditions, such as thinning bones (osteoporosis) or the blood condition anemia. You could have problems with walking and balance.

What is the general treatment for EPI?

Treatment for EPI is safe and improves general health The treatment for EPI consists of improving diet, decreasing alcohol and smoking, and a medication called PERT, which stands for pancreatic enzyme replacement therapy. PERT is taken by mouth to provide additional digestive enzymes during a meal.

What triggers EPI?

Chronic pancreatitis is the main cause of EPI in adults. As many as 8 in 10 adults with this disorder develop EPI. Pancreatitis causes inflammation and swelling of the pancreas. Over time, chronic inflammation can damage the pancreatic cells that make digestive enzymes.

What does EPI poop look like?

Foul-smelling, greasy stools (steatorrhea) People with EPI cannot absorb all of the fat that they eat. The undigested fat that passes through the digestive system may cause oily or greasy-looking stools. These stools may also smell really bad, float, and be difficult to flush.

Does EPI get worse with age?

As you age, it's possible for your pancreas not to work as well as it once did. If that happens, your EPI could worsen and trigger new symptoms, such as soreness, muscle weakness, weak bones, or numbness.

What is the difference between EPI and pancreatitis?

EPI and pancreatitis have some similar symptoms, such as abdominal discomfort, bloating, and gas. But EPI tends to be a complication of pancreatitis. The characteristic sign of EPI is pale, foul-smelling stools that can be difficult to flush.

What happens if EPI is left untreated?

If left untreated, exocrine pancreatic insufficiency can lead to feeling malnourished, fatigued and weak. This is due to the poor absorption of vitamins and nutrients. Eventually, it can lead to thinning bones (osteoporosis) or anemia (a deficiency of red blood cells).

How do you know if you have EPI?

The classic symptoms of EPI -- weight loss, greasy and foul-smelling stools that float or are tough to flush, stomach cramps, and diarrhea -- mimic the telltale signs of many other digestive diseases. You might even have one of those diseases along with EPI, like Crohn's or celiac disease.

Does EPI show up on CT scan?

An X-ray or computed tomography (CT) scan may help, and a fecal fat test can be effective, although it requires large stool samples. These tests are commonly used to help diagnose EPI: A fecal fat test involves looking at a stool sample under a microscope. The most common test, according to Dr.

Does EPI show up in blood test?

Blood tests A complete blood count (CBC) may reveal microcytic anemia due to iron deficiency or macrocytic anemia due to vitamin B-12 or folate malabsorption. Serum iron, vitamin B-12, and folate concentrations may help establish the diagnosis of EPI.

Lifestyle and Home Remedies

To improve your symptoms of EPI, talk to your doctor about potential lifestyle changes and accommodations that you can implement. The following are some steps you can take to improve your quality of life with EPI: 2

Prescriptions

If your doctor suspects that you have EPI, they may prescribe prescription medications to manage symptoms, including pancreatic enzyme replacement therapy (PERT).

Summary

If you are diagnosed with EPI, your doctor may recommend prescription medications and dietary and lifestyle modifications, such as cutting back or quitting smoking or drinking alcohol, as these lifestyle choices can promote inflammation.

A Word From Verywell

EPI can be greatly improved with PERT prescriptions. Pancreatic functioning can be improved when drinking and smoking are avoided or eliminated completely. That said, consult with your gastroenterologist about supplementing your low-fat meals with fat-soluble vitamins (A, D, E, K), as many people with EPI are low in these vitamins.

How to treat exocrine pancreatic insufficiency?

If your pancreas doesn’t function properly, you may need to do the digestive work for it. A healthy diet, the right supplements, and enzyme replacement therapy can all help you treat EPI. By Beth W. Orenstein Medically Reviewed by Robert Jasmer, MD. Last Updated: January 2, 2020.

What is the purpose of pancreatic enzymes?

Pancreatic enzyme supplement capsules contain a mixture of digestive enzymes, including lipase to break down fat, protease to assist with digestion of protein, and amylase for carbohydrates , according to PCA. The more fat in your meal, the higher the dose of enzymes you’ll likely need, Whitcomb says.

Does PERT help with EPI?

PERT can help you manage EPI and prevent malabsorption and gastric discomfort. You must work with your doctor to determine how much enzyme replacement you need , though, because everyone is different, according to Pancreatic Cancer Action, a charity based in Hampshire, England, that focuses on early diagnosis of pancreatic cancer . “Start with a moderate dose and adjust as necessary, depending on your symptoms,” Gardner says. “You can be tested after a few months to see how you’re responding.”

Do you need vitamin C for EPI?

Whitcomb. But people with EPI who take a successful dose of pancreatic enzymes may not need vitamin supplements, he says.

Does EPI cause diarrhea?

EPI can also cause gastric discomfort, including diarrhea, and weight loss, according to The National Pancreas Foundation (NPF). The pancreas is located deep in your belly, surrounded by other organs, including the small intestine, liver, and spleen.

What to do if you have exocrine pancreatic insufficiency?

If you have been diagnosed with exocrine pancreatic insufficiency (EPI), you should work with your doctor and nutritionist to make sure all your dietary needs are being met. If you are living with EPI, getting all of the nutrients you need may mean being prescribed pancreatic enzyme replacement therapy (PERT), following a nutrient rich diet, and taking vitamin supplements.

What is the name of the medicine that replaces the digestive enzymes that your pancreas normally produces?

If you have EPI, your doctor may prescribe PERT for you, so it's important to understand how it works. PERT is a medicine that replaces the digestive enzymes that your pancreas normally produces.

Does EPI affect your body?

Since EPI may affect your body's ability to absorb nutrients, getting all of the vitamins you need might take more than just eating well. Your doctor may prescribe vitamin and mineral supplements to help you maintain proper levels of the fat-soluble vitamins A, D, E, and K.

Is EPI a manageable condition?

EPI is a manageable condition. If you have been diagnosed with exocrine pancreatic insufficiency (EPI), you should work with your doctor and nutritionist to make sure all your dietary needs are being met.

What is the best treatment for EPI?

Pancreatic enzyme replacement therapies. Your doctor may start you on a prescription treatment called pancreatic enzyme replacement therapy, or PERT. PERTs are the main treatment for EPI—they replace the digestive enzymes that your pancreas isn’t producing anymore.

What is EPI in health?

EPI is associated with certain diseases and conditions that affect the pancreas. Some of these diseases you are born with, like cystic fibrosis, while others may occur later in life, as is the case with chronic pancreatitis. EPI may be associated with chronic pancreatitis and cystic fibrosis. If you have one of these conditions and symptoms ...

What is the condition of exocrine pancreatic insufficiency?

Exocrine pancreatic insufficiency (EPI) is a condition characterized by deficiency of the exocrine pancreatic enzymes, resulting in the inability to digest food properly, or maldigestion. Who gets EPI?

What is EPI associated with?

EPI may be associated with chronic pancreatitis and cystic fibrosis. If you have one of these conditions and symptoms of EPI, we recommend that you talk to your doctor. Resources: Animated Pancreas Patient on EPI. American Gastroenterological Association DigiReach. AGA whiteboard videos in English and Spanish.

What happens if you have EPI?

CARBOHYDRATES can be found in bread and pasta. Carbohydrates are broken down into sugars. If you have EPI, your pancreas cannot properly break down foods, resulting in poor digestion of nutrients—especially fats. Eating healthy is important for all of us.

Can EPI cause GI problems?

In addition to preventing adequate digestion, EPI produces uncomfortable gastrointestinal (GI) symptoms. Only your doctor can tell if your GI symptoms are due to EPI or another digestive ...

How to treat EPI?

Apart from a healthy diet, the main treatment for EPI is pancreatic enzyme replacement therapy (PERT). You take prescription pills that replace the enzymes your pancreas isn't making. These enzymes break down your food so you can more easily digest and absorb it. You have to take them during your meals.

How to diagnose EPI?

First, you may need some blood tests that check to see if you're getting enough vitamins and that your pancreas is making enough enzymes. Other blood tests can check for things that can lead to EPI, like cel iac disease. Continued.

Why do I have pain in my belly when I have EPI?

When you have EPI, you don't get the nutrition you need because your body can't absorb fats and some vitamins and minerals from foods. You might lose weight or have pain in your belly. There are drugs that work for most people that give you a new supply of enzymes, so you can go back to digesting food the right way.

What does it mean when you have EPI?

In people with EPI, it’s the exocrine function of the pancreas that is affected. When you have EPI, your body doesn’t have enough of the pancreatic enzymes needed to break down the food you eat. As a result, EPI affects the way your body digests food, causes unpleasant gastrointestinal (GI) symptoms, and may prevent you from getting ...

What does EPI stand for?

What is EPI? EPI stands for Exocrine Pancreatic Insufficiency —a condition in which the body does not have the right amount of pancreatic enzymes to properly break down food.

Can EPI be diagnosed?

The symptoms of EPI may be similar to other gastrointestinal disorders, which can make it a difficult condition to diagnose. Only your doctor can determine if EPI is the cause of your symptoms. Use our symptom checker to identify your symptoms and help start a discussion with your doctor. Learn about the symptoms of EPI.

What is the best treatment for EPI?

If this occurs, you may need to be prescribed a proton pump inhibitor , a drug that reduces the production of gastric acid.

What is EPI in diet?

If you’ve been diagnosed with exocrine pancreatic insufficiency ( EPI ), you’ve probably received guidance about your eating habits and have been prescribed pancreatic digestive enzymes to take with each meal. According to a review published in December 2016 in the journal Gut, pancreatic enzyme replacement therapy ...

Why does EPI persist despite PERT?

In some cases, EPI symptoms persist despite PERT because people misunderstand the instructions about how to correctly time their doses with their meals.

What to do if EPI isn't working?

What to Do When Your EPI Treatment Isn’t Working. If you’re treating your exocrine pancreatic insufficiency, but still experiencing symptoms, there are several steps you and your doctor can take to improve your condition. If you’ve been diagnosed with exocrine pancreatic insufficiency ( EPI ), you’ve probably received guidance about your eating ...

When should I take enzymes?

Research suggests that the optimal time to take enzymes is with meals, not before or after. Ask your doctor to review the specific medication instructions with you. Take the correct enzyme dosage. Know your correct dosage and take it as prescribed. But if EPI symptoms continue to bother you, Dr.

Is EPI enteric coated?

But in some people, this coating may not work as well; also, some enzymes may not be enteric-coated. In these cases, a proton pump inhibitor may help the enzymes work properly.

Does Pert help with EPI?

According to a review published in December 2016 in the journal Gut, pancreatic enzyme replacement therapy (PERT) has been shown to be highly effective at improving digestion in people with EPI. But enzyme therapy isn’t perfect, and despite taking it, many people still have EPI symptoms.

What to do if you think you have EPI?

If you think you might have EPI, talk to your doctor. They may send you to a doctor who treats stomach diseases , called a gastroenterologist. This specialist will test you and recommend treatments that can help.

Why do I get EPI?

This is the most common cause of EPI in adults. It happens when the pancreas has been inflamed for a long time. This can damage the organ and its enzymes. Heavy alcohol use and smoking cause chronic pancreatitis, but some types of it also run in families.

What causes EPI?

EPI starts in people who have a damaged pancreas or a health condition that keeps the organ from working as it should. You might be at risk if you have: 1 Surgery on your stomach, pancreas, or gallbladder 2 A disorder that affects your pancreas, like cystic fibrosis, Shwachman-Diamond syndrome, or pancreatic cancer 3 Stomach ulcers 4 Celiac disease

What is the EPI of the pancreas?

Chronic Pancreatitis . Cystic Fibrosis . Next Steps . Exocrine pancreatic insufficiency (EPI) is a condition that happens when there's a problem with your pancreas, mainly with how well it helps you digest food. Your pancreas makes enzymes that break down the fats, proteins, and starches you eat so your body can use them.

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Lifestyle and Home Remedies

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Exocrine pancreatic insufficiency (EPI) develops when your pancreas doesnt make or release enough digestive enzymes. This leaves undigested food in your intestines and causes gut pain, bloating, and diarrhea. Severe EPI can cause fatty, loose stools and weight loss from malnutrition. A variety of conditions can cause …
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Prescriptions

Summary

A Word from Verywell

Adverse effects

Causes

  • To improve your symptoms of EPI, talk to your doctor about potential lifestyle changes and accommodations that you can implement. The following are some steps you can take to improve your quality of life with EPI:2 1. Maintain a healthy diet:When you have EPI, take extra care with what and how you eat. Work with a dietitian so you can know exactly how to get proper nutrition …
See more on verywellhealth.com

Treatment

  • If your doctor suspects that you have EPI, they may prescribe prescription medications to manage symptoms, including pancreatic enzyme replacement therapy (PERT).
See more on verywellhealth.com

Diet

  • If you are diagnosed with EPI, your doctor may recommend prescription medications and dietary and lifestyle modifications, such as cutting back or quitting smoking or drinking alcohol, as these lifestyle choices can promote inflammation. Long-term treatment goals for patients with EPI will depend on the severity of your pancreas function at the tim...
See more on verywellhealth.com

Interactions

  • EPI can be greatly improved with PERT prescriptions. Pancreatic functioning can be improved when drinking and smoking are avoided or eliminated completely. That said, consult with your gastroenterologistabout supplementing your low-fat meals with fat-soluble vitamins (A, D, E, K), as many people with EPI are low in these vitamins. Additionally, while PERT is an effective treatme…
See more on verywellhealth.com

Definition

  • EPI is malnutrition specifically linked to the failure of the pancreas, says David C. Whitcomb, MD, PhD, chief of the division of gastroenterology, hepatology, and nutrition, and medical director of the Comprehensive Pancreas Program in the Liver-Pancreas Institute at the University of Pittsburgh and University of Pittsburgh Medical Center. EPI can also cause gastric discomfort, w…
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Risks

  • Your pancreas is made up of two small glands deep in your belly. One of its functions (the exocrine function) is to release enzymes that help break down the food you eat so your body can absorb its nutrients. Some people have diseases or conditions that affect the ability of their pancreas to release these enzymes. These include a tumor, pancreatic surgery, chronic pancreat…
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Prevention

  • Doctors can sometimes treat EPI at its root cause, like with celiac disease, for example, says Timothy B. Gardner, MD, an associate professor of medicine at the Geisel School of Medicine at Dartmouth in Lebanon, New Hampshire. Otherwise, EPI symptoms need to be treated with diet, vitamin and mineral supplements, and pancreatic enzyme replacement therapy (PERT). The goa…
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