Treatment FAQ

what is the treatment for a pituitary tumor

by Ms. Olga Balistreri Published 2 years ago Updated 2 years ago
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There are three types of treatment used for pituitary tumors: surgical removal of the tumor, radiation therapy using high-dose x-rays to kill tumor cells and medication therapy to shrink or eradicate the tumor.

Medication

Treatment

  • Surgery. During transsphenoidal endoscopic surgery, a surgeon accesses the pituitary tumor by inserting a tiny, specialized surgical instrument into the nostril and alongside the nasal septum.
  • Radiation therapy. Radiation therapy uses high-energy sources of radiation to destroy tumors. ...
  • Medications. ...
  • Replacement of pituitary hormones. ...
  • Watchful waiting. ...

Procedures

Surgery is necessary but it is unlikely to restore your gland to it’s pre-damaged state. One thing that really makes recovery from pituitary surgery (and surgery for Cushing’s in particular) so damn slow is that Cushing’s messed with the hypothalamic-pituitary-adrenal (HPA) axis long before the surgeon started poking around in your head.

Nutrition

Recovery after pituitary tumor surgery begins immediately in the hospital with close monitoring of vision, fluid intake and output and any nasal discharge from the surgery site. Surgery on the pituitary gland is a serious operation, and surgeons are very careful to try to limit any problems either during or after surgery.

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The treatment, if required, includes the following:

  • Prescription medicines like Bromocriptine and cabergoline work well for most patients.
  • Surgery is used to remove a tumor if medications do not prove to be effective.
  • Radiation is used, if both medications and surgery are not fruitful.

How do you remove a pituitary tumor?

Why is recovery from pituitary surgery so damn slow?

What is the recovery time from pituitary tumor removal?

What to do if you have a damaged pituitary gland?

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What is the best treatment for pituitary tumor?

Doctors generally use surgery, radiation therapy and medications, either alone or in combination, to treat a pituitary tumor and return hormone production to normal levels.

Is a pituitary tumor serious?

Most of these tumors are not cancerous. Pituitary cancer is very rare. Still, the tumors can cause serious problems, either because of their size (large tumors) or because they make extra hormones your body doesn't need (functioning tumors). They're typically treated with surgery, medicine, or radiation.

How are pituitary tumors treated?

Treatment may include the following:Surgery (usually transsphenoidal surgery) to remove the tumor, with or without radiation therapy.Radiation therapy alone.Drug therapy to stop the tumor from making ACTH.A clinical trial of stereotactic radiation surgery.

What is the survival rate for pituitary tumor?

The 5-year survival rate tells you what percent of people live at least 5 years after the tumor is found. Percent means how many out of 100. The 5-year survival rate for people with a pituitary gland tumor is 97%. Survival rates depend on the type of tumor, the person's age, and other factors.

Can you live a normal life with a pituitary tumor?

In general, when a pituitary tumor is not cured, people live out their lives but may have to deal with problems caused by the tumor or its treatment, such as vision problems or hormone levels that are too high or too low.

What happens if you leave a pituitary tumor untreated?

Most pituitary tumors are curable, but if left untreated, they can lead to serious complications such as complete vision loss.

How serious is pituitary tumor surgery?

Surgery on the pituitary gland is a serious operation, and surgeons are very careful to try to limit any problems either during or after surgery.

Can pituitary tumors be treated without surgery?

Radiation therapy uses high-energy x-rays to kill abnormal pituitary tumor cells. Radiation is extremely effective in stopping tumor growth and, with time, will lead to tumor shrinkage. Radiation therapy may be an option if the tumor cannot be treated effectively through medication or surgery.

Should I worry about pituitary tumor?

Even when a pituitary tumor never comes back, people still worry about it. For years after treatment ends, you will see your doctor. Be sure to go to all of these follow-up visits. You will have exams, blood tests, and maybe other tests to see if the tumor has come back.

Are pituitary tumors life threatening?

Pituitary tumors are common, but most are benign (noncancerous) and are almost never fatal. However, because the pituitary gland is located at the base of the skull, many pituitary tumors press against the optic nerves and thus cause vision problems.

Why do you get a pituitary tumor?

Most pituitary tumors are not cancers, and there are no known environmental causes for these tumors. The gene changes in these tumors might just be random events that sometimes happen when a cell divides, without having an outside cause.

Where does your head hurt with a pituitary tumor?

A person with pituitary tumor apoplexy usually has a sudden-onset, severe headache at the front of the head (either located on one side of the head or both) and/or behind one or both eyes.

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What kind of doctor treats pituitary tumors?

Pituitary tumors often require care from a team of doctors. Doctors on your team may include: Neurosurgeon: a doctor who uses surgery to treat brain and pituitary tumors. Endocrinologist: a doctor who treats diseases in glands that make hormones. Neurologist: a doctor who diagnoses and treats brain and nervous system diseases.

Why is it important to ask questions about pituitary tumors?

Because pituitary tumors are rare, not many doctors have much experience with them. You may want to get a second opinion. This can give you more information and help you feel more certain about the treatment plan you choose.

What are the services offered by the American Cancer Society?

These might include nursing or social work services, financial aid, nutritional advice, rehab, or spiritual help. The American Cancer Society also has programs and services – including rides to treatment, lodging, and more – to help you get through treatment.

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

Why are clinical trials important?

Clinical trials are one way to get state-of-the art cancer treatment. In some cases they may be the only way to get access to newer treatments. They are also the best way for doctors to learn better methods to treat cancer. Still, they're not right for everyone.

Can surgery be done to remove a tumor?

For example, surgery may be done to remove some of the tumor, while drugs can be used to relieve symptoms and sometimes shrink the remaining tumor. Common treatment plans differ by tumor type. Treatment of Functional (Hormone-Making) Pituitary Tumors. Treatment of Non-Functional Pituitary Tumors (Tumors That Don’t Make Excess Hormones) ...

Who is part of the cancer treatment team?

Many other specialists might be part of your treatment team as well, including physician assistants, nurse practitioners, nurses, psychologists, social workers, rehabilitation specialists, and other health professionals. Health Professionals Associated with Cancer Care.

What is pituitary tumor?

Key Points. A pituitary tumor is a growth of abnormal cells in the tissues of the pituitary gland. The pituitary gland hormones control many other glands in the body. Having certain genetic conditions increases the risk of developing a pituitary tumor. Signs of a pituitary tumor include problems with vision and certain physical changes.

How to describe pituitary tumors?

Pituitary tumors are described by their size and grade, whether or not they make extra hormones, and whether the tumor has spread to other parts of the body. The following sizes are used: Microadenoma: The tumor is smaller than 1 centimeter. Macroadenoma: The tumor is 1 centimeter or larger.

What happens if a pituitary tumor is not functioning?

Sometimes, a pituitary tumor may press on or damage parts of the pituitary gland, causing it to stop making one or more hormones. Too little of a certain hormone will affect the work of the gland or organ that the hormone controls.

What are the parts of the brain that are not cancerous?

Anatomy of the inside of the brain, showing the pineal and pituitary glands, optic nerve, ventricles (with cerebrospinal fluid shown in blue), and other parts of the brain. Pituitary tumors are divided into three groups: Benign pituitary adenomas: Tumors that are not cancer.

What is the purpose of pituitary tumor testing?

Once a pituitary tumor has been diagnosed, tests are done to find out if it has spread within the central nervous system (brain and spinal cord) or to other parts of the body.

How to stop a tumor from growing?

Treatment may include the following: Drug therapy to stop the tumor from making prolactin and to stop the tumor from growing. Surgery to remove the tumor ( transsphenoidal surgery or craniotomy) when the tumor does not respond to drug therapy or when the patient cannot take the drug. Radiation therapy .

Where is the pituitary gland located?

Pituitary tumors form in the pituitary gland, a pea-sized organ in the center of the brain, just above the back of the nose. The pituitary gland is sometimes called the "master endocrine gland " because it makes hormones that affect the way many parts of the body work.

How to remove pituitary tumor?

The surgeon may reach the pituitary gland through a cut made under the upper lip or at the bottom of the nose between the nostrils. In other cases, the surgeon may cut through the skull to reach the pituitary tumor.

What is the treatment for a tumor after surgery?

Even if the tumor is completely removed, patients are commonly given radiation and chemotherapy after surgery to kill any tumor cells that might be present. Radiation therapy . Radiation therapy involves targeting a tumor with high-energy X-rays that kill tumor cells or keep them from growing. Chemotherapy.

How does chemo help a tumor?

Chemotherapy uses drugs that kill tumor cells or keep them from growing. Chemotherapy can be taken by mouth or injected. The primary approach for treatment will depend on the type of pituitary tumor. To find out more about treatments for pituitary tumors, visit the National Cancer Institute's Treatment Option Overview section on pituitary tumors.

How to treat pituitary tumors?

The treatment for a pituitary tumor at the Johns Hopkins Pituitary Tumor Center will depend on many factors, including: 1 The location of the tumor 2 Whether the pituitary tumor produces excessive amounts of a specific hormone 3 The patient’s general health and preferences regarding potential treatment options

What do doctors do for pituitary tumors?

Doctors who specialize in pituitary tumors will help the patient understand the pituitary tumor. They will discuss the recommended treatment plan and other options so that the patient can make good decisions about care. A nurse or physician assistant will work closely with the doctors to coordinate each patient’s care.

Why do doctors work together to treat pituitary tumors?

Because having a pituitary tumor can affect many different organs and systems in the body, doctors from several medical specialties will work together to develop a customized treatment plan for the patient.

Can a pituitary tumor grow?

For a small pituitary tumor that does not cause any significant signs or symptoms, observation — keeping a close watch on the tumor without any immediate treatment — might be an option. If the pituitary tumor does not grow, the patient may never need treatment.

What is the best treatment for pituitary tumors?

Surgery is the most common treatment for pituitary tumors. If the pituitary tumor is benign and in a part of the brain where neurosurgeons can safely completely remove it, surgery might be the only treatment needed.

How to remove pituitary tumor?

This procedure involves making an incision in the patient’s scalp and removing a piece of bone from the skull. The neurosurgeon can then find and remove the tumor, or as much as the tumor as possible without risk of severe damage to the brain.

What is the most common type of surgery for pituitary tumors?

Is still growing despite previous treatment with medication or surgery. The most common types of surgery for pituitary tumors are: Endonasal endoscopic surgery. Neuroendoscopic surgery.

What is the procedure used to access the brain?

Neurosurgeons perform the procedure using an endoscope, a small telescope-like device equipped with a high-resolution video camera and a bright light.

Can a neurosurgeon remove pituitary tumors?

Neurosurgeons at the Johns Hopkins Pituitary Tumor Center can remove nearly all benign pituitary tumors using endonasal endoscopic surgery. This minimally-invasive approach enables neurosurgeons to: Remove tumors and lesions through the nose and sinuses, without cutting the face or the skull. Access areas of the brain that are difficult ...

What is the best treatment for pituitary tumors?

Cyproheptadine (Periactin) is an antihistamine drug that can suppress ACTH production in some of these tumors. Drugs called steroidogenesis inhibitors can be used to keep the adrenal gland from making cortisol, but they don’t affect the pituitary tumor itself.

What is the best treatment for a tumor that doesn't make hormones?

Even though these tumors don't make hormones, drugs may be used to treat them. Surgery and radiation are usually done first. Dopamine agonists and somatostatin analogs have been found to help slow or decrease growth in some of these tumors. These are discussed above in the lactotroph and somatotroph drug sections.

What is the name of the drug that blocks the growth hormone?

Drugs like octreotide (Sandostatin), lanreotide (Somatuline Depot), and pasireotide (Signifor LAR) are man-made forms of the natural hormone somatostatin. Somatostatin, which is made in the pituitary and other glands, blocks growth hormone (somatotropin) production by adenomas. These somatostatin-like drugs can return insulin-like growth factor-1 ...

What is the best treatment for thyrotroph adenomas?

Drugs for thyrotroph adenomas or thyrotropin (TSH)-secreting tumors. The first treatment for these rare tumors is typically surgery. If this doesn't cure the patient, somatostatin analogs such as octreotide and lanreotide can usually reduce the amount of TSH that's produced and may help shrink the tumor.

How often is octreotide given?

Octreotide is first given as an injection under the skin 3 times per day. A longer acting form is available, which can be given as a monthly injection.

What is the drug that can help with Cushing's disease?

Mifepristone (Korlym) is a type of drug called a cortisol receptor blocker. It limits the effects of cortisol on other tissues in the body. This drug can help treat high blood sugar levels in people with Cushing’s disease, but it doesn’t affect the pituitary tumor itself.

What medications can be taken after radiation?

These include osilodrostat (Isturisa), ketoconazole, aminoglutethimide , etomidate, metyrapone, and mitotane. These drugs can sometimes be helpful after surgery or radiation (or if surgery is not an option), but they can often be hard to take because of the side effects they can cause.

How to tell if you have pituitary tumor?

The presence of three or more of the following symptoms may indicate a pituitary tumor: 1 Vision problems (blurred or double vision, drooping eyelid) 2 Headaches in the forehead area 3 Nausea or vomiting 4 Impaired sense of smell 5 Sexual dysfunction 6 Depression 7 Fatigue 8 Infertility 9 Growth problems 10 Osteoporosis 11 Unexplained weight gain 12 Unexplained weight loss 13 Easy bruising 14 Aching joints 15 Carpal tunnel syndrome 16 Disrupted menstruation 17 Early menopause 18 Muscle weakness 19 Galactorrhea (spontaneous breast-milk flow not associated with childbirth or the nursing of an infant)

What is the function of the pituitary?

The pituitary constantly monitors bodily functions and sends signals to remote organs and glands to monitor their function and maintain the appropriate environment. The ideal "thermostat" setting for a body depends on many factors, including level of activity, gender, body composition, etc.

What are the two parts of the pituitary gland?

The pituitary is divided into distinct sections: the anterior pituitary gland and the posterior pituitary gland. Each part contains unique cells and releases different hormones that are responsible for specific control duties. The anterior pituitary is formed from the same tissue as the pharynx.

Why is the pituitary gland called the master gland?

The pituitary is often called the "master gland" because it controls the secretion of most of the hormones in the body. A normal pituitary gland weighs less than 1 gram and is about the size and shape of a kidney bean. The function of the pituitary can be compared to that of a household thermostat.

Which lobe of the pituitary gland is responsible for producing the majority of the signaling hormones released

The anterior pituitary accounts for about 80 percent of the pituitary gland size and is composed of the anterior lobe and the intermediate zone. The anterior lobe is responsible for producing the majority of the signaling hormones released into the blood stream.

What is the fourth most common intracranial tumor?

Pit uitary Adenoma s. Pituitary adenomas are the fourth most common intracranial tumor after gliomas, meningiomas and schwannomas. A large majority of pituitary adenomas are benign and are relatively slow growing. Adenomas are by far the most common disease affecting the pituitary gland.

How does radiation therapy help tumors?

Radiation Therapy. Radiation therapy uses high-energy x-rays to kill abnormal pituitary tumor cells. Radiation is extremely effective in stopping tumor growth and, with time, will lead to tumor shrinkage. Radiation therapy may be an option if the tumor cannot be treated effectively through medication or surgery.

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Diagnosis

Clinical Trials

Coping and Support

Preparing For Your Appointment

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment depends on type of tumor, size and spread into the brain.
Medication

Prolactin-secreting tumors: Reduces prolactin secretion and often shrinks the tumor size.

Cabergoline . Bromocriptine


Growth hormone-secreting tumors: To regularize the hormone production.

Somatostatin . Pegvisomant

Procedures

Endoscopic transnasal transspheidal surgery: To remove the tumor through the nose and sinuses without external incision.

Craniotomy: The tumor is removed through the upper part of the skull.

Gamma knife stereotactic radiosurgery: Tumor is removed using a focused radiation beams.

Nutrition

Foods to eat:

  • Plenty of vegetables such as broccoli, kale
  • Fruits such as strawberries, oranges, grapefruit
  • Omega 3 fatty acid rich foods such as flaxseeds, walnuts, soybeans, canola oil
  • Lean meat such as beef, fish, poultry
  • Foods that contain high level of anti-oxidants such as blueberries, raspberries, tomatoes, red grapes

Foods to avoid:

  • Limit sugary Foods such as sodas
  • Fatty Foods such as fried potatoes
  • Avoid smoking

Specialist to consult

Neurosurgeon
Specializes in surgery on the nervous system, especially the brain and spinal cord.
Oncologist
Specializes in the diagnosis and treatment of cancer.
Endocrinologist
Specializes in the function and disorders of the endocrine system of the body.
Ophthalmologist
Specializes in the medical and surgical care of the eyes.
Primary care physician
Specializes in the acute and chronic illnesses and provides preventive care and health.

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