Treatment FAQ

what is the primary treatment for colorectal cancer

by Mavis Kuhic MD Published 2 years ago Updated 2 years ago
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The treatment of choice for colon cancer is surgical resection, which involves removing the cancer through surgery. Surgery is performed to remove the cancer completely and reconstruct the bowel, if possible, so your postoperative bowel function is normal or near normal.

Medication

Treatments may include one or more of these:

  • Removing the rectal cancer with surgery
  • Surgery to create a colostomy and bypass the rectal cancer (a diverting colostomy)
  • Using a special laser to destroy the cancer within the rectum
  • Placing a stent (hollow metal tube) within the rectum to keep it open; this does not require surgery
  • Chemoradiation therapy
  • Chemo alone

Procedures

  • The best treatment for colorectal cancer is prevention. ...
  • Include 25–30 grams of fiber in your diet every day and avoid processed foods or things that are high in saturated fat, such as red meat and pork. ...
  • If you have an immediate relative who has had colon cancer, start getting screened 10 years earlier than when your relative was diagnosed. ...

More items...

Therapy

People with a diagnosis of stage 4 cancer have a 5-year relative survival rate of about 14 percent, meaning that 14 out of 100 people who have stage 4 colon cancer are still alive after 5 years. In comparison, those with stage 1 cancer have a 5-year relative survival rate of about 90 percent.

Nutrition

Treatment for colon cancer usually involves surgery to remove the cancer. Other treatments, such as radiation therapy and chemotherapy, might also be recommended. Surgery for early-stage colon cancer. If your colon cancer is very small, your doctor may recommend a minimally invasive approach to surgery, such as:

See more

What is the best medicine for colon cancer?

How to cure colorectal cancer?

What are the cure rates for colon cancer?

How treatable is colorectal cancer?

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What is the first line treatment for colorectal cancer?

In many cases, bevacizumab is recommended as a component of the first-line treatment of metastatic colorectal cancer, along with FOLFIRI, FOLFOX, FOLFOXIRI, or XELOX/CAPOX.

Which type of treatment is most common for colorectal cancer?

Treatment for colon cancer usually involves surgery to remove the cancer. Other treatments, such as radiation therapy and chemotherapy, might also be recommended.

What is standard of care for colorectal cancer?

Standard of care for the majority of patients is the combination of 5-fluorouracil (FU)/leucovorin (LV) with either oxaliplatin (FOLFOX) or irinotecan (FOLFIRI) together with a monoclonal antibody (moAb) against either vascular endothelial growth factor (VEGF) or epidermal growth factor receptor (EGFR) [6].

What is the primary treatment of choice for non metastatic colorectal cancer?

Surgery is the primary form of treatment and results in cure in approximately 50% of the patients. Recurrence following surgery is a major problem and is often the ultimate cause of death.

How is Stage 1 colon cancer treated?

The main treatment is surgery to remove the cancer. You might have a type of surgery called: trans anal endoscopic microsurgery (TEM) – the surgeon removes the cancer along with a border (margin) of healthy tissue (you have this if you have a very early stage, low risk cancer)

Can colon cancer be treated without chemo?

For advanced cancers, radiation therapy can also be used to help prevent or relieve symptoms in the colon from the cancer such as pain. It might also be used to treat areas of spread such as in the lungs or bone. It may shrink tumors for a time, but it's not likely to cure the cancer.

What is the difference between colorectal cancer and colon cancer?

Colorectal cancer is a disease in which cells in the colon or rectum grow out of control. Sometimes it is called colon cancer, for short. The colon is the large intestine or large bowel. The rectum is the passageway that connects the colon to the anus.

How is colon cancer removed?

A colectomy is surgery to remove all or part of the colon. Nearby lymph nodes are also removed. If only part of the colon is removed, it's called a hemicolectomy, partial colectomy, or segmental resection. The surgeon takes out the part of the colon with the cancer and a small segment of normal colon on either side.

At what stage of cancer is chemotherapy used?

Usually, chemotherapy may be used for all stages in most cancer types. Chemotherapy is a type of medicine or combination of medications that is used to treat or kill cancer cells. Adjuvant therapy: Chemotherapy may be used after surgery to reduce the risk of cancer recurrence (coming back).

Is colon cancer treatable if caught early?

“Overall, colorectal cancer is highly preventable, and if detected early, it's also one of the most curable types of cancer,” Dr. Lipman notes. Up to 85% of colorectal cancers could be prevented or successfully treated if everyone who is eligible for a colonoscopy got screened.

What's the prognosis for colon cancer?

For colon cancer, the overall 5-year survival rate for people is 64%. If the cancer is diagnosed at a localized stage, the survival rate is 91%. If the cancer has spread to surrounding tissues or organs and/or the regional lymph nodes, the 5-year survival rate is 72%.

What happens if a removed polyp is cancerous?

If a cancerous polyp is removed completely during colonoscopy with no cancer cells at the edges of the polyp, then no additional treatment may be needed. If there are cancer cells at the edges of the polyp, additional surgery may be needed.

Treating Stage 0 Colon Cancer

Since stage 0 colon cancers have not grown beyond the inner lining of the colon, surgery to take out the cancer is often the only treatment needed....

Treating Stage I Colon Cancer

Stage I colon cancers have grown deeper into the layers of the colon wall, but they have not spread outside the colon wall itself or into the nearb...

Treating Stage II Colon Cancer

Many stage II colon cancers have grown through the wall of the colon, and maybe into nearby tissue, but they have not spread to the lymph nodes.Sur...

Treating Stage III Colon Cancer

Stage III colon cancers have spread to nearby lymph nodes, but they have not yet spread to other parts of the body.Surgery to remove the section of...

Treating Stage IV Colon Cancer

Stage IV colon cancers have spread from the colon to distant organs and tissues. Colon cancer most often spreads to the liver, but it can also spre...

Treating Recurrent Colon Cancer

Recurrent cancer means that the cancer has come back after treatment. The recurrence may be local (near the area of the initial tumor), or it may b...

What is the cancer in the colon?

The cancer had blocked (obstructed) the colon. The cancer caused a perforation (hole) in the wall of the colon.

What is stage 1 colon cancer?

Stage I colon cancers have grown deeper into the layers of the colon wall, but they have not spread outside the colon wall itself or into the nearby lymph nodes. Stage I includes cancers that were part of a polyp. If the polyp is removed completely during colonoscopy, with no cancer cells at the edges (margins) ...

Where does stage IV colon cancer spread?

Stage IV colon cancers have spread from the colon to distant organs and tissues. Colon cancer most often spreads to the liver, but it can also spread to other places like the lungs, brain, peritoneum (the lining of the abdominal cavity), or to distant lymph nodes. In most cases surgery is unlikely to cure these cancers.

What does it mean when cancer comes back?

Recurrent cancer means that the cancer has come back after treatment. The recurrence may be local (near the area of the initial tumor), or it may be in distant organs.

Does stage 3 colon cancer spread to other parts of the body?

Stage III colon cancers have spread to nearby lymph nodes, but they have not yet spread to other parts of the body. Surgery to remove the section of the colon with the cancer (partial colectomy) along with nearby lymph nodes, followed by adjuvant chemo is the standard treatment for this stage. For chemo, either the FOLFOX (5-FU, leucovorin, ...

Can colon cancer spread to lymph nodes?

Many stage II colon cancers have grown through the wall of the colon, and maybe into nearby tissue, but they have not spread to the lymph nodes. Surgery to remove the section of the colon containing the cancer (partial colectomy) along with nearby lymph nodes may be the only treatment needed. But your doctor may recommend adjuvant chemotherapy ...

Can you get rid of liver cancer with chemo?

For tumors in the liver, another option may be to destroy them with ablation or embolization. If the cancer has spread too much to try to cure it with surgery, chemo is the main treatment. Surgery might still be needed if the cancer is blocking the colon or is likely to do so.

What is the most common treatment for colorectal cancer?

Surgery is the removal of the tumor and some surrounding healthy tissue during an operation. It is often called surgical resection. This is the most common treatment for colorectal cancer. Part of the healthy colon or rectum and nearby lymph nodes will also be removed.

What is standard of care for colorectal cancer?

This section explains the types of treatments that are the standard of care for colorectal cancer. “Standard of care” means the best treatments known. When making treatment plan decisions, you are encouraged to consider clinical trials as an option.

What is a colorectal surgeon?

A surgical oncologist is a doctor who specializes in treating cancer using surgery. A colorectal surgeon is a doctor who has received additional training to treat diseases of the colon, rectum, and anus. Colorectal surgeons used to be called proctologists.

What is included in a cancer care plan?

Treatment options and recommendations depend on several factors, including the type and stage of cancer, possible side effects, and the patient’s preferences and overall health.

How is medication used to treat cancer?

Medication may be given through the bloodstream to reach cancer cells throughout the body. When a drug is given this way, it is called systemic therapy . Medication may also be given locally, which is when the medication is applied directly to the cancer or kept in a single part of the body.

What is clinical trial?

Clinical trials can test a new drug , a new combination of standard treatments, or new doses of standard drugs or other treatments. Clinical trials are an option to consider for treatment and care for all stages of cancer. Your doctor can help you consider all your treatment options.

Can you get chemotherapy for stage 3 cancer?

People with stage II and III rectal cancer will also receive radiation therapy with chemotherapy either before or after surgery .

What is the procedure to check for colon cancer?

Colonoscopy. During a colonoscopy , the doctor inserts a colonoscope into your rectum to check for abnormalities in your entire colon. If your signs and symptoms indicate that you could have colon cancer, your doctor may recommend one or more tests and procedures, including:

What tests are needed for colon cancer?

Staging helps determine what treatments are most appropriate for you. Staging tests may include imaging procedures such as abdominal, pelvic and chest CT scans.

How does chemotherapy help with colon cancer?

Chemotherapy uses drugs to destroy cancer cells. Chemotherapy for colon cancer is usually given after surgery if the cancer is larger or has spread to the lymph nodes. In this way, chemotherapy may kill any cancer cells that remain in the body and help reduce the risk of cancer recurrence.

What is the earliest stage of colon cancer?

At its earliest stage (stage 0), colon cancer is limited to the inner lining of your colon. As colon cancer progresses, it can grow through your colon and extend to nearby structures. The most advanced stage of colon cancer (stage IV) indicates cancer has spread to other areas of the body, such as the liver or lungs.

How to tell what stage of colon cancer you have?

The stages of colon cancer are indicated by Roman numerals that range from 0 to IV, with the lowest stages indicating cancer that is limited to the lining of the inside of the colon.

What is the treatment for cancer?

Immunotherapy. Immunotherapy is a drug treatment that uses your immune system to fight cancer. Your body's disease-fighting immune system may not attack your cancer because the cancer cells produce proteins that blind the immune system cells from recognizing the cancer cells.

How does radiation therapy work?

Radiation therapy uses powerful energy sources, such as X-rays and protons, to kill cancer cells. It might be used to shrink a large cancer before an operation so that it can be removed more easily. When surgery isn't an option, radiation therapy might be used to relieve symptoms, such as pain.

What is colon cancer?

Key Points. Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon. Health history affects the risk of developing colon cancer. Signs of colon cancer include blood in the stool or a change in bowel habits. Tests that examine the colon and rectum are used to diagnose colon cancer.

What are the risk factors for colon cancer?

Risk factors for colorectal cancer include the following: Having a family history of colon or rectal cancer in a first-degree relative (parent, sibling, or child). Having a personal history of cancer of the colon, rectum, or ovary.

Where does colon cancer spread?

Cancer has spread from the mucosa of the colon wall to the submucosa or to the muscle layer. In stage I colon cancer, cancer has formed in the mucosa (innermost layer) of the colon wall and has spread to the submucosa (layer of tissue next to the mucosa) or to the muscle layer of the colon wall.

How do you know if you have colon cancer?

Signs of colon cancer include blood in the stool or a change in bowel habits. These and other signs and symptoms may be caused by colon cancer or by other conditions. Check with your doctor if you have any of the following: A change in bowel habits. Blood (either bright red or very dark) in the stool.

Where are abnormal cells found in the colon?

Abnormal cells are shown in the mucosa of the colon wall. In stage 0, abnormal cells are found in the mucosa (innermost layer) of the colon wall. These abnormal cells may become cancer and spread into nearby normal tissue. Stage 0 is also called carcinoma in situ.

How does chemo work?

When chemotherapy is taken by mouth or injected into a vein or muscle , the drugs enter the bloodstream and can reach cancer cells throughout the body ( systemic chemotherapy ). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas ( regional chemotherapy ).

Which system is cancer in?

Lymph system. The cancer gets into the lymph system , travels through the lymph vessels, and forms a tumor ( metastatic tumor) in another part of the body. Blood. The cancer gets into the blood, travels through the blood vessels, and forms a tumor (metastatic tumor) in another part of the body.

How many types of colorectal cancer treatments are there?

The National Institutes of Health classify seven different types of colorectal treatments overall, adding four more treatment options as offshoot treatments in addition to the main three: radiofrequency ablation, cryosurgery, targeted therapy, and immunotherapy—all offered depending on the stage of a patient's cancer.

How invasive is colon surgery?

If colorectal cancer is caught in early stages, a surgeon may take out only a small amount of the colon through a process called local excision, according to the NIH.

How many people will have colon cancer in 2020?

In 2020, it was estimated that 12% of all colorectal cancer diagnoses would be in those under 50, amounting to about 18,000 cases.

What is immunotherapy for cancer?

As it implies, immunotherapy uses the patient's immune system to fight cancer. Medical oncologists will use substances, such as certain proteins, made either in the body or in the lab to boost, direct, or restore the body's immune system in hopes that it will target the invading cancer cells, according to the NIH.

Where does colorectal cancer spread?

Typically, colorectal cancer that spreads goes to the liver or the lungs, but once the cancer gets into the bloodstream or the lymphatic system (a network of tissues, vessels, and organs), it can spread anywhere. When it spreads, doctors classify it as metastatic colorectal cancer.

Can a temporary colon bag be used for colon surgery?

In emergency colon surgeries, a temporary bag may be used to allow the colon to heal. However, if the doctor needs to remove the entirety of the lower colon, the bag may be permanent. Permanent colostomy bags are more common when the colorectal cancer is found in the rectum, Dr. Rajput says.

Can colorectal cancer be prevented?

Colorectal cancer is extremely preventable if the polyps are caught early. But if they aren't, they can puncture the intestine, causing bleeding or obstruction of the waste moving through the digestive tract, and travel from the colon or rectum to other parts of the body.

What is the best treatment for colon cancer?

For patients with locally recurrent and/or liver-only and/or lung-only metastatic disease, surgical resection , if feasible, is the only potentially curative treatment.

What are the risk factors for colorectal cancer?

Increasing age is the most important risk factor for most cancers. Other risk factors for colorectal cancer include the following: Family history of colorectal cancer in a first-degree relative. [ 2] Personal history of colorectal adenomas, colorectal cancer, or ovarian cancer. [ 3 - 5]

Should colon cancer be diagnosed in older adults?

Because of the frequency of the disease, ability to identify high-risk groups, slow growth of primary lesions, better survival of patients with early-stage lesions, and relative simplicity and accuracy of screening tests, screening for colon cancer should be a part of routine care for all adults aged 50 years and older , especially for those with first-degree relatives with colorectal cancer. (Refer to the PDQ summary on Colorectal Cancer Screening for more information.)

Is aspirin a cure for colon cancer?

Cancer of the colon is a highly treatable and often curable disease when localized to the bowel. Surgery is the primary form of treatment and results in cure in approximately 50% of the patients. Recurrence following surgery is a major problem and is often the ultimate cause of death.

Is CEA a screening test for colon cancer?

CEA is a serum glycoprotein frequently used in the management of patients with colon cancer. A review of the use of this tumor marker suggests the following: [ 42] A CEA level is not a valuable screening test for colorectal cancer because of the large numbers of false-positive and false-negative reports.

What is the third most common cancer in men?

Colorectal cancer (CRC) is the third most frequent cancer in men, after lung and prostate cancer, and is the second most frequent cancer in women after breast cancer. It is also the third cause of death in men and women separately, and is the second most frequent cause of death by cancer if both genders are considered together.

How many people will die from cancer in 2030?

The global cancer rate has doubled in the last 30 years of the 20th century, and will almost triple by 2030, a year in which it is foreseen that 20.3 million people will be diagnosed with cancer and 13.2 million will die as a result of this disease.2. CRC is the third most frequent cancer in men, after lung and prostate cancer, ...

Is colon cancer a worldwide problem?

Cancer is a worldwide problem as it will affect one in three men and one in four women during their lifetime. There is no doubt whatsoever which environmental factors, probably diet, may account for these cancer rates. Excessive alcohol consumption and cholesterol-rich diet are associated with a high risk of colon cancer.

Does alcohol cause colon cancer?

Excessive alcohol consumption and cholesterol -rich diet are associated with a high risk of colon cancer. A diet poor in folic acid and vitamin B6 is also associated with a higher risk of developing colon cancer with an overexpression of p53.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Karthikeya T M
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves surgery and chemotherapy.
Medication

Targeted drugs: The specific sites which can be cancerous are targeted and the drugs are administered.

Bevacizumab . Ramucirumab


Chemotherapy: To destroy the cancer cells and relieve symptoms.

5-Fluorouracil . Capecitabine . Irinotecan . Oxaliplatin


Immunotherapy: To treat the type of cancers which might respond to the antibodies.

Nivolumab . Pembrolizumab

Procedures

Colonoscopy: To visualize and remove/biopsy the polyps.

Laparoscopy: To remove the polyps which can not be removed using colonoscopy.

Endoscopic mucosal resection: Procedure where a small section of the colon lining that has cancerous tissue is removed.

Bowel resection with colostomy: Involves creating another way for elimination of connecting healthy tissue to a pouch attached to skin and removing the cancerous tissue.

Lymphadenectomy: Nearby lymph nodes are removed and tested for malignancy so as to ensure the death of all the cancerous cells.

Partial colectomy: Removal of the part of colon with cancer and then reconnecting it with healthy tissue.

Therapy

Radiation therapy:Therapy involves the usage of high energy beams like X-rays to destroy cancer cells.

Nutrition

Foods to eat:

  • low-fat high-fiber diet – fruits and vegetables
  • Antioxidants – kidney beans, goji berries, wild berries

Foods to avoid:

  • high fat fast foods
  • Red meat

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Gastroenterologist
Specializes in the digestive system and its disorders.
Colon and rectal surgeon
Specializes in dealing with disorders of the rectum, anus, and colon.

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