Treatment FAQ

what is optune treatment

by Walton Pfannerstill Published 2 years ago Updated 2 years ago
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Optune is a wearable, portable, FDA-approved treatment for glioblastoma (GBM) that works by creating Tumor Treating Fields (TTFields), which are electric fields that disrupt cancer cell division. See how people use Optune. day to day.

How long does optune treatment last?

Using a model developed to simulate the growth kinetics of a malignant tumor, the minimal treatment duration for Optune has been determined to be approximately 4 weeks to reach tumor stabilization.

How many months do you use optune?

average patient usage of Optune for the first 6 months of treatment (months 1-6).

Does optune prolong life?

In a large clinical study, people who added Optune to chemotherapy* had a greater opportunity to live longer than those who used chemotherapy* alone. Nearly half of people using Optune + chemotherapy* were alive at 2 years compared with 31% of people on chemotherapy* alone.

Is glioblastoma always fatal?

Glioblastoma incidence is very low among all cancer types, i.e., 1 per 10 000 cases. However, with an incidence of 16% of all primary brain tumors it is the most common brain malignancy and is almost always lethal [5,6].

What is the survival rate for Stage 4 glioblastoma?

That is the survival rate for stage 4 glioblastoma: four percent. Four out of 100. That is the survival rate for stage 4 glioblastoma: four percent.May 23, 2019

Does optune work for GBM?

Optune is a wearable, portable, FDA-approved treatment for glioblastoma (GBM) that works by creating Tumor Treating Fields (TTFields), which are electric fields that disrupt cancer cell division. day to day.

Can immunotherapy cure glioblastoma?

Northwestern Medicine scientists have discovered a new biomarker to identify which patients with brain tumors called glioblastomas — the most common and malignant of primary brain tumors — might benefit from immunotherapy. The treatment could extend survival for an estimated 20% to 30% of patients.Nov 29, 2021

Does optune make you tired?

What are the possible side effects of Optune? Most common side effects of Optune when used together with chemotherapy (temozolomide, or TMZ) were low blood platelet count, nausea, constipation, vomiting, tiredness, scalp irritation from the device, headache, seizure, and depression.

Can optune cause swelling?

Fatigue: Constant tiredness has been reported as a common side-effect of this therapy. Infection: In rare cases, infections have been reported at the site of contact with the skin. Telltale signs are a feeling of heat in the area, swelling, redness, or even pain.Aug 17, 2020

Can glioblastoma go into remission?

In remission, symptoms may let up or disappear for a time. Glioblastomas often regrow. If that happens, doctors may be able to treat it with surgery and a different form of radiation and chemotherapy.Dec 11, 2021

What is the longest someone has lived with glioblastoma?

As of July 20, 2017, Sandy Hillburn is an 11-year survivor of glioblastoma.Jul 20, 2017

What is end of life like with glioblastoma?

Results: A total of 57 patients, who died due to glioblastoma in a hospital setting, were included. The most frequent signs and symptoms in the last 10 days before death were decrease in level of consciousness (95%), fever (88%), dysphagia (65%), seizures (65%), and headache (33%).

What are the side effects of a syringe?

The side effects of this therapy include: 3 . Allergic reaction: Some patients report rashes or skin discomfort due to the gel used for conduction of the device. Overheating: Due to malfunction, cases have been reported where one or more transducers become very hot, leading to pain and/or burns on the skin.

Is Optune safe for cancer patients?

The good news about Optune, in contrast to most cancer therapies, is that adverse effects are rarer and rarely outright dangerous. That said, it’s your job to be mindful of how you’re feeling and to keep your doctor in the loop. The side effects of this therapy include: 3 

Does optune interact with food?

As you’re undergoing this treatment be mindful of its effects on your body. Optune therapy will not interact with foods or drugs you’re taking, though drugs it’s co-administered with, like Temodar, very well may. Here’s what you should look out for: 5 

What is the Optune device?

Optune is a device that delivers low-intensity electrical fields to stop cancer spread. 1  Worn on the head and indicated for adult patients, this device emits what are called tumor treating fields (TTF) directly to affected areas.

Who is Mark Gurarie?

Mark Gurarie is a freelance writer, editor, and adjunct lecturer of writing composition at George Washington University. Doru Paul, MD, is board-certified in internal medicine, medical oncology, and hematology. Optune is a newer treatment approach for taking on glioblastoma (GBM), the most common form of brain cancer.

Is Optune the best treatment for cancer?

Precautions and Contraindications. As with any cancer therapy, using the Optune device may not be the best approach for everyone. As you’re being evaluated for treatment, you’ll need to let your doctor know as much as possible about your medical history, and medications or any other supplements you’re taking.

What are the symptoms of GBM?

GBM symptoms arise once tumor growth has started impacting other parts of the brain and include headache, nausea, vomiting, and fatigue, with other symptoms arising based on the specific location of the cancer. According to the Food and Drug Administration (FDA), Optune is indicated for adult patients who have: 3 .

Which is better, version 1 or version 2?

It is much better to the user than version one. Version two is about 1/3 the size and weight, and the batteries last approximately hours at a time. It is much easier to carry around. Everyone I know who was on version one agrees - version two is much better.

Does Optune work?

It has worked for many people though. In my non-doctor terms (layman's terms), the Optune device, when turned on, puts a specific range of radio waves into your head. In the late 1990s', an Israeli researcher found that a specific range of radio waves freezes cancer cells in place.

Is optune good for cancer?

Best case scenario I think would be to use Optune to survive long enough for cancer research to identify and get approved a solution treatment for GBM. Given the current (relatively fast) pace of cancer research, Optune is a great option right now. At a minimum, if worn, it should slow down cancer cells regrowth.

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Uses

  • As noted above, the Optune device is indicated to treat glioblastoma. This brain cancer is aggressive, and it has been shown to develop either from adult neural stem cells or oligodendrocyte progenitor cells. GBM symptoms arise once tumor growth has started impacting other parts of the brain and include headache, nausea, vomiting, and fatigue, with...
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Before Using

  • Proper diagnosis of GBM is required prior to starting Optune treatment. Typically, there’s a progression of tests and evaluations, which includes a physical examination, imaging, and biopsy.4
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Dosage

  • Unlike pharmaceutical drugs, Optune treatment relies on TTF electrical signals for its therapeutic effect, and, as such side-effects and adverse reactions are rarer with this therapy. The device goes on the head and consists of two main components: an electric field generator (the emitting device itself) as well as the transducer arrays that deliver the TTF to the brain.3In addition, a po…
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Side Effects

  • Common
    The good news about Optune, in contrast to most cancer therapies, is that adverse effects are rarer and rarely outright dangerous. That said, it’s your job to be mindful of how you’re feeling and to keep your healthcare provider in the loop. The side effects of this therapy include:3 1. Allergic …
  • Severe
    Keep in mind that when chemotherapy or other treatments are indicated alongside Optune—which represents a majority of cases—there will be a much wider set of side effects and potentially adverse reactions. That said, studies have shown that Optune use will not accelerate or worsen t…
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Warnings and Interactions

  • As you’re undergoing this treatment be mindful of its effects on your body. Optune therapy will not interact with foods or drugs you’re taking, though drugs it’s co-administered with, like Temodar, very well may. Here’s what you should look out for:5 1. Skin irritation:As mentioned above, skin irritation and allergic reaction commonly occur during the course of treatment. Let your healthca…
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