Treatment FAQ

what happens after all treatment stops working for prostate csncer

by Brandi Renner I Published 3 years ago Updated 2 years ago

It is also important to note that many patients still have unpleasant symptoms related to their treatment for months or even years after treatment ends. Unfortunately, it is common for patients to experience fatigue, difficulty sleeping, problems with memory, persistent pain or tingling from neuropathy, and emotional distress.

Full Answer

What happens next after prostate cancer treatment?

 · Cancer treatments can help stop cancer from growing or spreading. But sometimes treatment does not work well or stops working. Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing. If this happens, your doctor might say ...

Will I have erectile dysfunction after prostate cancer treatment?

For many men with localised or locally advanced prostate cancer, treatment is successful and gets rid of the cancer. But sometimes not all the cancer is successfully treated, or the cancer may have been more advanced than first thought. If this happens, your cancer may come back – this is known as recurrent prostate cancer.

What to do if prostate cancer doesn't go away?

 · Common side effects from prostate cancer treatment include: Urinary problems Being unable to hold urine, or experiencing urine leakage, is common after treatment, especially if you’ve had surgery....

Does cancer treatment stop working?

 · Hormone therapy is treatment to stop your body from producing the male hormone testosterone. Prostate cancer cells rely on testosterone to help them grow. Cutting off the supply of testosterone may cause cancer cells to die or to grow more slowly. Hormone therapy options include: Medications that stop your body from producing testosterone.

What happens when hormone therapy stops working for prostate cancer?

Most prostate cancers eventually stop responding to hormone therapy and become castration (or castrate) resistant. That is, they continue to grow even when androgen levels in the body are extremely low or undetectable.

What happens in end stage prostate cancer?

With advanced disease, mainly if you have not had treatment to the prostate itself, you may have problems passing urine or see blood in your urine. Some men may feel tired, weak or lose weight. When prostate cancer spreads to bones, you may have bone pain.

What happens when cancer treatment is stopped?

If the decision to stop treatment is made, at some point, you might benefit from hospice care. At the end of life, hospice care focuses on your quality of life and helping you manage your symptoms. Hospice care treats the person rather than the disease; it focuses on the quality of your life rather than its length.

How long can you live with incurable prostate cancer?

The researchers demonstrated that a patient with incurable, castration-resistant prostate cancer receiving a novel targeted therapy will live for around 41 months – just under three-and-a-half years – on average. This is up from an average of 13-16 months on average in the era before docetaxel-based chemotherapy.

What are the symptoms of the last stages of prostate cancer?

Signs and symptoms of stage 4 prostate cancer may include:Painful urination.Decreased force in the stream of urine.Blood in the semen.Bone pain.Swelling in the legs.Fatigue.

What causes death in prostate cancer patients?

Most notably, heart failure and external causes were listed as the underlying cause of death, whereas urinary tract disease, diseases of the pulmonary circulation, and anemia were more frequently listed among multiple causes of death. Mechanisms have been proposed linking these conditions to both PC and its treatment.

How do you know when cancer patient is dying?

Signs that death has occurredBreathing stops.Blood pressure cannot be heard.Pulse stops.Eyes stop moving and may stay open.Pupils of the eyes stay large, even in bright light.Control of bowels or bladder may be lost as the muscles relax.

How do doctors know how long a cancer patient will live?

Ask your doctor about the stage of your cancer and how much it has spread. Ask about your prognosis, or how long you have to live. No one can know exactly, but your doctor should be able to tell you a range of months or years. And you need to know if more treatment for cancer will help you live longer.

How do you know if cancer cells are dying?

When cancer cells die, they can cause inflammation. Small blood vessels become leaky, leading to redness and swelling. Cells of the immune system migrate to the area and can release chemicals and proteins that cause damage to the structures/cells nearby., and chronic inflammation supports the growth of cancer.

What is the average life expectancy with stage 4 prostate cancer?

Stage-4 Prostate Cancer (IV) This is the last stage of prostate cancer and describes a tumor that has spread to other parts of the body, including the lymph nodes, lungs, liver, bones, or bladder. For these cancers, the 5-year survival rate is 29%.

What are the signs that prostate cancer has spread?

Prostate cancer can spread to the lymph nodes in the groin area, or to other parts of the body. The most common symptoms are swelling and pain around the area where the cancer has spread. Cancer cells can stop lymph fluid from draining away. This might lead to swelling in the legs due to fluid build up in that area.

What is the life expectancy with a Gleason score of 9?

Maximum estimated lost life expectancy for men with Gleason score 5 to 7 tumors was 4 to 5 years and for men with Gleason score 8 to 10 tumors was 6 to 8 years. Tumor histologic findings and patient comorbidities were powerful independent predictors of survival.

What happens if cancer stops working?

Or maybe one type of cancer treatment has stopped working and the cancer has kept growing. If this happens, your doctor might say your cancer has advanced or progressed. There may or may not be other treatment options. But when many different treatments have been tried and are no longer controlling the cancer, it could be time to weigh ...

How to trust your doctor about cancer?

Trusting your cancer care team. Talking with your doctor and cancer care team, and trusting them to be honest, open, and supportive, is very important. You will have more confidence in treatment decisions if you trust the doctors making recommendations. This means communication is a key part of your care, from diagnosis throughout treatment ...

Can cancer shrink?

If you have cancer that keeps growing or comes back after one kind of treatment, it’s possible that another treatment might still help shrink the cancer, or at least keep it in check enough to help you live longer and feel better. Clinical trials also might offer chances to try newer treatments that could be helpful.

Can you get a second opinion on cancer?

When faced with deciding whether to continue cancer treatment, some patients or their loved ones may want to get a second opinion. Even when you place full trust in your doctor and cancer care team, you might wonder if another doctor could offer something else or more information. It's normal to think about talking to someone else, and your doctor should support you if you decide to get another opinion. Remember that your cancer care team wants you to be sure about the decisions you make. You can read more in Seeking a Second Opinion.

Does cancer stop working?

If Cancer Treatments Stop Working. Cancer treatments can help stop cancer from growing or spreading. But sometimes treatment does not work well or stops working. Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing.

Is there hope for a life without cancer?

Staying hopeful. Your hope for a life without cancer might not be as bright, but there is still hope for good times with family and friends – times that are filled with happiness and meaning. Pausing at this time in your cancer treatment gives you a chance to refocus on the most important things in your life.

Why do men not undergo cancer treatment?

Others men may choose to not undergo cancer treatment because of a short life expectancy or other serious medical problems.

What is active surveillance prostate cancer?

Known as active surveillance, it is common when the cancer is expected to grow slowly based on biopsy results, confined to the prostate, not causing any symptoms, and/or small. In active surveillance, doctors will initiate cancer treatment only if cancer starts growing.

Where does prostate cancer spread?

Prostate cancer is known to have a particular affinity for spreading or metastasizing to the bones especially the lower spine, pelvis, and femur. 3  Other organs such as the liver, brain, or lungs can also be the sites of spread, but these are much rarer.

Can prostate cancer spread to other parts of the body?

If left untreated, diagnosed prostate cancer can grow and possibly spread outside of the prostate to local tissues or distantly to other sites in the body. The first sites of spread are typically to the nearby tissues.

Can prostate cancer be treated?

The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative and completely kill or remove whatever cancer cells are present. 1 . If left untreated, however, prostate cancer can proceed on a number of different paths.

Is prostate cancer confined to the prostate?

With regard to prostate cancer, most cases of the disease are discovered while the cancer is still confined to the prostate itself. 1  This is called “local disease” or “localized disease.”. The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative ...

Can prostate cancer spread through the capsule?

The cancer can spread down the blood vessels, lymphatic channels, or nerves that enter and exit the prostate, or cancer could erode directly through the capsule that surrounds the prostate.

How long does it take for PSA to drop after prostate surgery?

PSA level after surgery (radical prostatectomy) Your PSA level should drop so low that it’s not possible to detect it (less than 0.1 ng/ml) at six to eight weeks after surgery. This is because the prostate, which produces PSA, has been removed.

How long does it take for a prostate to drop?

PSA level after radiotherapy or brachytherapy. After radiotherapy or brachytherapy, your PSA should drop to its lowest level (nadir) after 18 months to two years.

What tests are done to check for prostate cancer?

If your doctor or nurse is concerned about your PSA level or if you have new symptoms that suggest your cancer might have come back, they may recommend that you have some other tests, such as a prostate biopsy , MRI scan, CT scan , bone scan or PET scan.

What happens if you have cancer and it comes back?

If your cancer does come back, the first sign is likely to be a rise in your PSA level, rather than any symptoms. And problems will often be side effects of treatment rather than a sign that your cancer has come back.

How do you know if your cancer has come back?

PSA levels after treatment. A continuous rise in your PSA level can be the first sign that your cancer has come back. This should be picked up by your regular PSA tests. The exact change in PSA level that suggests your cancer has come back will depend on which treatment you had.

Can prostate cancer come back?

If this happens, your cancer may come back – this is known as recurrent prostate cancer.

Can you have PSA after a follow up appointment?

After your follow-up appointments finish, you may continue to have PSA tests. Speak to your GP if you have any problems or concerns – they can refer you back to the hospital. Make sure you remind them about your prostate cancer, especially if it’s been a while since you had treatment or a PSA test.

What to do if you are ending prostate cancer treatment?

If you’re ending prostate cancer treatments, you and your doctor should discuss a care plan.

How to get rid of prostate cancer?

Getting regular physical exercise and staying active is a great way to boost your overall health. Additionally, research shows that men who exercise after prostate cancer treatment may be less likely to die than men who don’t. A 2008 study also shows that men who are overweight or obese may have a poorer outcome than men who are at ...

How to help people with cancer?

Contact your hospital’s education and outreach office. Many local hospitals have support groups for people who have cancer and people who have cancer that’s in remission. Some even offer support groups for caretakers, spouses, and partners.

Can you connect with a support group for prostate cancer?

You can connect with a support group, call the helpline to speak with a trained support team member, or subscribe to newsletters to find up-to-date treatment options.

Can prostate cancer be found during follow up?

In many cases, recurrent prostate cancer is found during follow-up visits. Men who’ve had prostate cancer may be more likely to develop other types of cancer. If your doctor finds that your cancer has returned, the two of you should address these questions:

Can prostate cancer cause fatigue?

The effects of some prostate cancer treatments, such as radiation and chemotherapy, may cause you to experience fatigue and tiredness. These symptoms may begin during treatment and continue after you’ve entered remission.

Can you keep an erection after prostate cancer?

Trouble getting and keeping an erection is common following prostate cancer treatment. This may be an issue for several months or even years following cancer treatment. Some men may be able to resolve this with treatment for ED.

What is the lowest stage of prostate cancer?

Your doctor uses the information from these tests to assign your cancer a stage. Prostate cancer stages are indicated by Roman numerals ranging from I to IV. The lowest stages indicate the cancer is confined to the prostate. By stage IV, the cancer has grown beyond the prostate and may have spread to other areas of the body.

What is prostate radiation?

Prostate cancer radiation therapy treatments may involve: Radiation that comes from outside of your body (external beam radiation). During external beam radiation therapy, you lie on a table while a machine moves around your body, directing high-powered energy beams, such as X-rays or protons, to your prostate cancer.

Where is the incision for prostate cancer?

During an open prostatectomy, one large incision is made in your abdomen (left). During a robotic prostatectomy, several smaller incisions are made in the abdomen (right). Surgery for prostate cancer involves removing the prostate gland (radical prostatectomy), some surrounding tissue and a few lymph nodes.

What is the best way to monitor prostate cancer?

In active surveillance, regular follow-up blood tests, rectal exams and prostate biopsies may be performed to monitor progression of your cancer. If tests show your cancer is progressing, you may opt for a prostate cancer treatment such as surgery or radiation.

What tests are done to determine if prostate cancer is spread?

If your doctor suspects your cancer may have spread beyond your prostate, one or more of the following imaging tests may be recommended: Bone scan. Ultrasound. Computerized tomography (CT) scan.

What is the most common scale used to evaluate the grade of prostate cancer cells?

Gleason score. The most common scale used to evaluate the grade of prostate cancer cells is called a Gleason score. Gleason scoring combines two numbers and can range from 2 (nonaggressive cancer) to 10 (very aggressive cancer), though the lower part of the range isn't used as often.

What is the next step in a biopsy?

When a biopsy confirms the presence of cancer, the next step is to determine the level of aggressiveness (grade) of the cancer cells. A doctor in a lab examines a sample of your cancer cells to determine how much cancer cells differ from the healthy cells.

What is the treatment for recurrent prostate cancer called?

Treatments for recurrent prostate cancer are called second-line or salvage treatments . Many of the treatments used to treat prostate cancer when it’s first diagnosed can also be used as second-line treatments.

What happens if you have cancer and it comes back?

If your cancer does come back, the first sign is likely to be a rise in your PSA level, rather than any symptoms. However, it’s important to let your doctor or nurse know if you do get any new symptoms or side effects, or are worried that your cancer might have come back.

Where does prostate cancer spread?

Prostate cancer can spread to any part of the body but it most commonly spreads to the bones and lymph nodes. Prostate cancer that has spread to other parts of the body is known as advanced prostate cancer. Sometimes it’s not clear where the cancer is.

Can prostate cancer be picked up?

Small groups of cells might have been left behind. Over time, these may have grown large enough to be picked up by tests or to cause symptoms.

Can prostate cancer cause fatigue?

Advanced prostate cancer (cancer that has spread from the prostate to other parts of the body) can cause symptoms, such as extreme tiredness (fatigue), bone pain and problems urinating. Physical problems will often be side effects of treatment rather than a sign that your cancer has come back.

What tests can I do to check if my cancer has come back?

These may include a CT (computer tomography), MRI (magnetic resonance imaging), bone, or PET (positron emission tomography) scan.

How do you know if you have prostate cancer?

Usually the first sign that your cancer is starting to return is a continuous rise in the level of prostate specific antigen (PSA) in your blood. The PSA test is a very effective way of checking how successful your treatment has been. It can't show for certain if prostate cancer has come back, or where it might be. But it can be a useful sign that the cancer may have come back. The exact change in PSA level that suggests your cancer has come back depends on which treatment you had. Read more about PSA levels after different treatments.

What happens after cancer treatment?

A: We hear from many patients that the time after completing active cancer treatment is a time when they feel ‘unsettled’ and worry about an uncertain future. Some may even feel anxious about the possibility that the cancer could return and worry they may not be doing enough to catch any signs early enough. It is also important to note that many patients still have unpleasant symptoms related to their treatment for months or even years after treatment ends. Unfortunately, it is common for patients to experience fatigue, difficulty sleeping, problems with memory, persistent pain or tingling from neuropathy, and emotional distress.

What is the end of treatment summary?

A: Survivors can ask their oncologist for an end of treatment summary that outlines the original diagnosis, including the cancer type, stage, and the treatments received. These details will be important to future health care providers throughout their lifetime. This information should also clearly state the proposed schedule for follow-up visits and recommended scans and other testing to monitor the person's recovery, also called a "survivorship care plan."

How to deal with cancer fears?

Information and education are essential to regain some control. Sharing one’s fears and worries with loved ones, a support group, or seeking professional help can and will bring relief. It is normal to have many concerns after completing treatment for cancer and important to feel supported and accompanied in this journey.

Do cancer survivors want to give back?

Many cancer survivors want to give back, and you will find them volunteering or acting as advocates at cancer clinics and philanthropic organizations. It's also important to recognize that many cancer survivors face an uncertain future and feel unsettled.

How do you know if you have prostate cancer?

Prostate cancer that is more advanced may cause signs and symptoms such as: 2 . Trouble urinating. Decreased force in the stream of urine. Blood in the semen. Discomfort in the pelvic area.

Where does prostate cancer develop?

Prostate cancer develops in the prostate—a small gland that makes seminal fluid. It is the second most common type of cancer in men. 1  Prostate cancer usually grows over time and in the beginning stays within the prostate gland, where it may not cause serious harm. While some types of prostate cancer grow slowly and may need minimal ...

Does Viagra help with ED?

For men who have undergone prostatectomy, long-term ED has been seen in up to 67% percent of men, but some studies have shown that using medications such as Viagra may help to achieve erectile functioning. 6 .

Can a man have ED after treatment?

Unfortunately, there is no definitive way to determine which men will have ED following treatment. In general, men with vascular conditions, diabetes, obesity, or pre-existing erectile problems are at greater risk for ED. 4 

Can men have ED after prostate surgery?

Studies that have sought to determine the chance of men having ED following prostatectomy, radiation, and other prostate cancer treatments have resulted in widely varying numbers. 5  Some studies seem to show that only a small percentage of men have long-standing issues with ED, while others have shown much higher numbers.

Does prostate cancer cause permanent ED?

All of the currently available, potentially curative treatment options for prostate cancer can result in temporary or permanent erectile dysfunction (ED), though many men who undergo treatment for prostate cancer see little or no ill effects to their erectile function. 3  Radiation therapy, prostate surgery, cryotherapy, hormone therapy, and others can all result in ED.

Can you have an erection after prostate cancer treatment?

Following prostate cancer treatment of any kind, it is a possibility that you will no longer be able to have an erection. 3  If you are unable to have an erection following treatment, this condition may last only for a short time or could be permanent.

Why do people stop taking prostate medications?

In advanced prostate cancer, patients may decide to stop the medications because of the severe side effects and opt for palliative care, which is available in many hospitals.

How long does it take to die from prostate cancer?

About two-thirds of men who receive a diagnosis of stage 4 prostate cancer will die within five years. However, these men already are of advanced age, Dr. Brawley said.

Can prostate cancer be stage 4?

There are plenty of men that survive stage 4 prostate cancer so that’s not the real “final stage” in the case of prostate cancer. Usually what happens if the metastatic areas cannot be reduced with radiation (prostate cancer metastasizes to the bones first then lungs, bladder, or kidneys ), is that eventually there will be pain, then other organ systems will shut down. There are a lot of new medications that can hold this disease at bay from months to years.

Is there a reason to continue living with cancer?

Depending on the cancer, the pain can be debilitating, ruthless, and unbearable even with massive pain killer doses. At that point there is zero quality of life and, therefore, no reason to continue living NO MATTER what your family says. They're not suffering your pain. Before you are too out of it due to meds to make a legal decision, it is time to request assisted dying (I really don't care what religious zealots say) and go in peace. With zero quality of life there is really no reason to continue living. If your jurisdiction

What are the symptoms of prostate cancer?

Paraneoplastic syndrome associated with prostate cancer cause symptoms such as neuropathy, difficulty walking, loss of muscle tone, loss of fine motor coordination, memory loss, seizures, sensory loss in the limbs, and vertigo or dizziness. Advanced stage cancer leads to malnutrition, muscle wasting, weight loss, and fatigue. It may even repress the healthy immune system to an extent that the person develops fungal infections and sepsis.

What is the condition that causes bone calcium to be released into the blood at the very end stages of metastasized prostate

Metastasis to the bone causes too much bone calcium to be released into the blood at the very end stages of Metastasized Stage 4 prostate cancer. The condition is known as hypercalcemia that can disrupt the functioning of organs, such as the kidney and heart. In severe cases, high calcium levels can lead to death.

Is prostate cancer curable?

Treatments response is slowed down or cancer shrinks in advanced prostate cancer is at a reduced rate. For most men, stage 4 prostate cancer isn't curable. Still, treatments are able to extend the life and reduce the signs and symptoms of cancer patients.

Management

Image
While most men undergo some form of treatment for their prostate cancer, some men today choose to not be treated for their prostate cancer. Instead, they may choose to have their doctors monitor their cancer, especially if it's expected to grow slowly based on biopsy results, confined to the prostate, not causing any sympto…
See more on verywellhealth.com

Risks

  • Others choose no cancer treatment because of a short life expectancy or other serious medical problems. They may feel that the risks or side effects of cancer treatment (like surgery and radiation) outweigh their potential benefits. This option is certainly OK and reasonable in the right circumstancesrequiring a careful and thoughtful discussion with your doctor and family.
See more on verywellhealth.com

Treatment

  • The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative and completely kill or remove whatever cancer cells are present. If left untreated, however, prostate cancer can proceed on a number of different paths. Prostate cancer is a complicated disease and requires extremely careful thought when determin…
See more on verywellhealth.com

Pathophysiology

  • If left untreated, most cases of diagnosed prostate cancer will grow and possibly spread outside of the prostate to local tissues or distantly to other sites in the body. The first sites of spread are typically to the nearby tissues. The cancer can spread down the blood vessels, lymphatic channels, or nerves that enter and exit the prostate, or can...
See more on verywellhealth.com

Clinical significance

  • Further advancement of cancer can occur when cancer cells enter the blood vessels and lymphatic channels. Once cancer has entered into these vessels, prostate cancer cells can seed into virtually any other part of the body. Prostate cancer is known to have a particular affinity for spreading or metastasizing to the bones especially the lower spine, pelvis, and femur. Other org…
See more on verywellhealth.com

Prognosis

  • It's important to know (and it's fairly well known) that, sometimes, even when untreated, prostate cancer simply does not continue to grow or only grows at an extremely slow rate. In fact, some studies have shown that prostate cancer is present in the majority of older men at the time of their deaths even if they had not been diagnosed. This suggests that many older men have prostate c…
See more on verywellhealth.com

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