Precautions
Zmax is used in adults and in children over the age of 6 months against bacteria to treat certain kinds of pneumonia (lung infections) Zmax is used in adults against bacteria to treat sinus infections. Zmax only works against bacteria.
What is Zmax used to treat?
Zmax is an antibiotic that kills certain bacteria. Zmax is dosed differently from other antibiotics. You take just one dose, one time. Day 1: Take Zmax in one dose. Zmax starts working. Days 2 – 3: As with most antibiotics, you may not feel better right away. After Day 3: Zmax continues to work over time.
How is Zmax dosed?
Zmax is a prescription medicine used to treat the symptoms of bacterial infections such as Pneumonia, Pharyngitis, Tonsillitis, skin infections and many others. Zmax may be used alone or with other medications. Zmax belongs to a class of drugs called Macrolides. It is not known if Zmax is safe and effective in children younger than 6 months of age.
Is Zmax safe for babies?
The incidence of treatment-related gastrointestinal adverse reactions was 17% for Zmax and 10% for pooled comparators. Treatment-related adverse reactions following Zmax treatment that occurred with a frequency of < 1% included the following:
What is the incidence of adverse reactions to Zmax?
What does zMAX do for your engine?
No matter what year your vehicle is, it needs zMAX Micro-lubricant® to disperse carbon build-up in your engine, fuel system and transmission. This helps improve performance, extend engine life and reduce emissions.
Is zMAX good for diesel engines?
Yes. zMAX works in diesel or gasoline engines.
Is zMAX a mineral oil?
It starts as highly refined mineral oil, not a synthetic, and the molecular structure is further refined to create what zMAX calls a “micro-lubricant.”
Does zMAX really work?
0:173:32I can't believe what ZMAX engine formula did to my engine! - YouTubeYouTubeStart of suggested clipEnd of suggested clipNot sure how that works improves fuel mileage by adding every six thousand miles reduces engine wearMoreNot sure how that works improves fuel mileage by adding every six thousand miles reduces engine wear makes the engine run more smoothly. And lower emissions trusted by professionals.
How often should you use Zmax?
Easy to use, add zMAX Micro-lubricant to your engine oil and fuel (gasoline or diesel) every 6 months or 6,000 miles. Use in your transmission after each flush.
Where do you put Zmax?
Instructions for use: Pour zMAX Fuel Formula (12oz.) in the fuel system with at least 1/2 tank of gas or diesel fuel. Pour zMAX Engine Formula (12oz.) into your crankcase.
Is Zmax flammable?
Flammability: Low Fire Hazard. This Material must be heated before ignition will occur. Reactivity: Stable under normal conditions.
How do you use bestline engine treatment?
0:399:50How to do a oil change using Bestline + 0-100mph video (Ready for texas)YouTubeStart of suggested clipEnd of suggested clipAnd can be used in your water pumps. So in your coolant.MoreAnd can be used in your water pumps. So in your coolant.
What happened to the original Slick 50?
The original Slick 50 (pre 1984) formula is now sold under the name Xcelplus. Q Is it true that Xcelplus is the original Slick 50 formula? A Yes. In 1983 John Bishop the inventor discontinued the supply of the formula to Petrolon who marketed Slick 50.
What is Zmax microsphere?
Zmax is an extended-release microsphere formulation . Based on data obtained from studies evaluating the pharmacokinetics of azithromycin in healthy adult subjects a higher peak serum concentration (C max) and greater systemic exposure (AUC 0–24) of azithromycin are achieved on the day of dosing following a single 2 g dose of Zmax versus 1.5 g of azithromycin tablets administered over 3 days (500 mg/day) or 5 days (500 mg on day 1, 250 mg/day on days 2–5) [Table 2]. Consequently, due to these different pharmacokinetic profiles, Zmax is not interchangeable with azithromycin tablet 3-day and 5-day dosing regimens.
How much azithromycin is in Zmax?
Each bottle of Zmax contains azithromycin dihydrate equivalent to 2 g of azithromycin. After constitution with 60 mL of water, each mL of suspension contains 27 mg of azithromycin. The suspension is a white or off-white color and has a cherry/banana flavor.
What is Zmax oral suspension?
Zmax (azithromycin extended-release) for oral suspension contains the active ingredient azithromycin (as azithromycin dihydrate), an azalide, a subclass of macrolide antibacterial drug.
How much does Zmax weigh?
The Zmax dose in mL is equivalent to the child's weight in lb (1 mL/lb dose, see Table 1 below), for a body weight of less than 75 lb (34 kg). It is recommended that Zmax be taken on an empty stomach (at least 1 hr before or 2 hrs following a meal).
What is Zmax used for?
Zmax is used in adults and in children over the age of 6 months against bacteria to treat certain kinds of pneumonia (lung infections) Zmax is used in adults against bacteria to treat sinus infections. Zmax only works against bacteria.
How long does azithromycin treatment last?
Following the use of azithromycin in neonates (treatment up to 42 days of life), IHPS has been reported. Direct parents and caregivers to contact their physician if vomiting or irritability with feeding occurs.
Is Zmax based on gender?
However, previous studies have demonstrated no significant differences in the disposition of azithromycin between male and female subjects. No dosage adjustment of Zmax is recommended based on gender.
For Auto, Home & Shop
No matter what year your vehicle is, it needs zMAX Micro-lubricant ® to disperse carbon build-up in your engine, fuel system and transmission. This helps improve performance, extend engine life and reduce emissions.
zMAX...only takes a minute
For auto, home and shop, zMAX has products for all of your engines, tools, equipment and more.
Can you take Zmax while pregnant?
If you are 65 or older, use Zmax (azithromycin extended-release oral suspension) with care. You could have more side effects. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
Can you take Zmax with any other medication?
You must check to make sure that it is safe for you to take Zmax (azithromycin extended-release oral suspension) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
How much azithromycin is in Zmax?
Each bottle of Zmax contains azithromycin dihydrate equivalent to 2 g of azithromycin. After constitution with 60 mL of water, each mL of suspension contains 27 mg of azithromycin. The suspension is a white or off-white color and has a cherry/banana flavor.
What is Zmax oral suspension?
Zmax (azithromycin extended-release) for oral suspension contains the active ingredient azithromycin (as azithromycin dihydrate), an azalide, a subclass of macrolide antibacterial drug. Azithromycin has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13- [ (2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyra nosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11- [ [3,4,6-trideoxy-3- (dimethylamino)β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azithromycin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C 38 H 72 N 2 O 12, and its molecular weight is 749.0. Azithromycin has the following structural formula:
How much does Zmax weigh?
The Zmax dose in mL is equivalent to the child's weight in lb (1 mL/lb dose, see Table 1 below), for a body weight of less than 75 lb (34 kg). It is recommended that Zmax be taken on an empty stomach (at least 1 hr before or 2 hrs following a meal).
What is the formula for azithromycin?
Azithromycin has the following structural formula: Azithromycin, as the dihydrate, is a white crystalline powder with a molecular formula of C 38 H 72 N 2 O 12 •2H 2 O and a molecular weight of 785.0.
What are laboratory abnormalities with an incidence of greater than or equal to 1%?
Laboratory abnormalities with an incidence of greater than or equal to 1%: reduced lymphocytes and increased eosinophils; reduced bicarbonate. Laboratory abnormalities with an incidence of less than 1%: leukopenia, neutropenia, elevated bilirubin, AST, ALT, BUN, creatinine, alterations in potassium.
Is Zmax based on gender?
However, previous studies have demonstrated no significant differences in the disposition of azithromycin between male and female subjects. No dosage adjustment of Zmax is recommended based on gender.
How long does diarrhea last after Zmax?
Diarrhea can occur as late as two or more months after you take an antibiotic such as Zmax.
How long does it take for a Zmax to soak?
With a 12-oz bottle, zMax states that it takes about 1,000 miles or 30-hours to “fully soak into the metal,” or return to a normal fluid level. It is all based on heat cycles. The hot cycle weeps out the lubricant while the cold cycle draws it in. Commonly, it takes several heat cycles for the fluid level to resettle.
What engine did Enstrom use for the Great Lakes?
In the early 1970s, the Chicago Manufacturing Engineering branch for the Great Lakes Region along with WGN radio in Chicago (Excetuive Helicopter provided the maintenance for the helicopters) tested Enstrom lycholming HIO-360 C1C engines to increase the teardown rate and reduce the number of replaced cylinders.
How often should I use Zmax?
“We recommend that you use zMAX every 6 months or 6,000 miles ,” Rachanski continued. ”This maintains the protection provided by zMAX.”.
Is Zmax an advertiser?
That makes evaluating additives – like zMax, difficult. In the interests of full disclosure, zMAX is an advertiser. However, we also wanted to look into the product and evaluate it’s merit.
What is the meaning of "dry start"?
This is the true meaning of a dry start. Joe started working with oil, playing with the molecular structure. He came upon a mixture he called the “Speedway Cocktail” and began using it in his engines. Skip forward to WWII, where Lencki was a supervisor at a Dodge plant in Chicago, building B-29 bombers.
Does Zmax replace oil?
It bears noting that zMAX does not replace the oils and fluids, it is solely an additive that assists in preventing internal wear. Due to the flexibility of anti-wear additives such as zMax, these products also work in diesel and small-engine applications, as well as turbochargers.
Does Zmax have a fluid level?
Unlike several other additives that raise the fluid level, zMAX claims it will initially, but over time will return to normal because of its ability to soak into the metal itself, a claim backed by the aforementioned Aujer Electron Spectroscopy Test results.
What are the side effects of Zmax?
Common side effects of Zmax include: decreased sense of taste or smell . Tell your doctor if you have unlikely but serious side effects of Zmax including: eye problems (such as drooping eyelids, blurred vision), signs of liver problems (such as unusual tiredness, persistent nausea or vomiting, severe stomach or abdominal pain, ...
What are the symptoms of a drug reaction?
Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Call your doctor at once if you have:
What are the symptoms of a syringe?
Call your doctor at once if you have: 1 severe stomach pain, diarrhea that is watery or bloody; 2 fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); or 3 liver problems --nausea, vomiting, loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
Why are clinical trials not compared to clinical trials?
Clinical Trials Experience. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Adults.
What are laboratory abnormalities with an incidence of greater than or equal to 1%?
Laboratory abnormalities with an incidence of greater than or equal to 1%: reduced lymphocytes and increased eosinophils; reduced bicarbonate. Laboratory abnormalities with an incidence of less than 1%: leukopenia, neutropenia, elevated bilirubin, AST, ALT, BUN, creatinine, alterations in potassium.
Can azithromycin cause vomiting?
liver problems --nausea, vomiting, loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); Call your doctor right away if a baby taking azithromycin becomes irritable or vomits while eating or nursing.
Can you take Zmax while pregnant?
Zmax During Pregnancy or Breastfeeding. Tell your doctor if you are pregnant or plan to become pregnant before using Zmax; it is not expected to harm a fetus. It is unknown if Zmax passes into breast milk. Consult your doctor before breastfeeding.
DESCRIPTION
Macrolide antibiotic similar in structure to erythromycin, but can be dosed systemically once daily Used systemically for otitis media, pharyngitis, community-acquired pneumonia, sexually transmitted diseases, and Mycobacterium avium complex (MAC) prophylaxis and treatment in patients with advanced HIV disease; an ophthalmic solution is used for bacterial conjunctivitis Produces less GI intolerance and reaches higher intracellular concentrations than erythromycin.
HOW SUPPLIED
Azasite Ophthalmic Drops: 1% Azithromycin/Zithromax Intravenous Inj Pwd F/Sol: 2.5g, 500mg Azithromycin/Zithromax Oral Pwd F/Recon: 1g, 5mL, 100mg, 200mg Azithromycin/Zithromax/Zithromax Tri-Pak/Zithromax Z-Pak Oral Tab: 250mg, 500mg, 600mg Zmax Oral Susp ER: 2g
DOSAGE & INDICATIONS
500 mg PO on day 1, followed by 250 mg PO once daily for at least 5 days as monotherapy for patients without comorbidities or risk factors for MRSA or P. aeruginosa and as part of combination therapy for patients with comorbidities. Guide treatment duration by clinical stability.
MAXIMUM DOSAGE
500 mg/day PO is FDA-approved dosage; however, doses up to 1,200 mg/day PO are used off-label; 2 g PO when given as single dose; 500 mg/day IV infusion.
DOSING CONSIDERATIONS
Dosage adjustment recommendations are not available; azithromycin has not been studied in patients with impaired hepatic function.
ADMINISTRATION
May be taken with or without food; however, increased tolerability has been observed when the tablets are taken with food.
DRUG INTERACTIONS
Aclidinium; Formoterol: (Major) Avoid coadministration of azithromycin with long-acting beta-agonists due to the increased risk of QT prolongation.
Indications and Usage For Zmax
This medication is an antibiotic used to treat certain bacterial infections.
May Treat: Chlamydia trachomatis pelvic inflammatory disease · Chlamydia trachomatis urethritis · Haemophilus influenzae acute otitis media · Haemophilus influenzae pneumonia · Legionella pneumophila pneumonia and more
Alternate Brand Names: Zithromax
Drug Class: Macrolide Antibiotics · Ophthalmic Antibiotic - Macrolides
Availability: Prescription Required
Pregnancy: Consult a doctor before using
May Treat: Chlamydia trachomatis pelvic inflammatory disease · Chlamydia trachomatis urethritis · Haemophilus influenzae acute otitis media · Haemophilus influenzae pneumonia · Legionella pneumophila pneumonia and more
Alternate Brand Names: Zithromax
Drug Class: Macrolide Antibiotics · Ophthalmic Antibiotic - Macrolides
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Does not adversely affect lactation
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: PFIZER US PHARM
Zmax Dosage and Administration
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
- The zMAX Micro-lubricant formula works the same way in your firearms, small engines and other equipment by soaking into metal to break up carbon deposits. This "soaking in" allows zMAX to stay in the metal and slowly weep out providing continuous protection. Provides easier cleaning for firearms and easier starts for small engines. Read why custome...
Use in Specific Populations
- Acute Bacterial Sinusitis in Adults and Community-Acquired Pneumonia
Zmax (azithromycin) is a macrolide antibacterial drug indicated for the treatment with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. [See Clinical Studies (14)] Acute bacterial sinusitis in adults due to Haemophilus influenzae, Moraxella catarrhalis or … - Limitations of Use
Zmax is not recommended for use in patients with pneumonia who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors such as any of the following: 1. patients with cystic fibrosis, 2. patients with nosocomial infections, 3. patients with known or suspected bacteremia, 4. patients requiring hos…
Overdosage
- Adults
Zmax should be taken as a single 2 g dose. Zmax provides a full course of antibacterial therapy in a single oral dose. It is recommended that Zmax be taken on an empty stomach (at least 1 hr before or 2 hr following a meal). - Pediatric Patients
For pediatric patients 6 months and older, Zmax should be taken as a single dose of 60 mg/kg (equivalent to 27 mg/lb) body weight. The Zmax dose in mL is equivalent to the child's weight in lb (1 mL/lb dose, see Table 1below), for a body weight of less than 75 lb (34 kg). It is recommended that Zmax be taken on an empty stoma…
Zmax Description
- Each bottle of Zmax contains azithromycin dihydrate equivalent to 2 g of azithromycin. After constitution with 60 mL of water, each mL of suspension contains 27 mg of azithromycin. The suspension is a white or off-white color and has a cherry/banana flavor.