Medication
Henoch-Schonlein purpura (HSP) is a short-term inflammation of certain blood vessels (vasculitis) thought to be triggered by a malfunction of the immune system. The cause of this malfunction is unknown, but HSP tends to develop after an upper respiratory tract infection or a bout of hay fever.
Procedures
Purpura lesions can take quite some time to heal, usually between one to three weeks if left untreated, and they may sometimes leave a yellow residue behind that takes months—or even years—to go away. As purpura is the direct result of aging, there's not much that people can do to prevent lesions from forming.
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What causes Henoch Schonlein purpura?
The following could cause thrombocytopenic purpura:
- medications that prevent platelets from forming or that interfere with normal clotting
- drugs that cause the body to launch an immune reaction against platelets
- recent blood transfusions
- immune disorders such as idiopathic thrombocytopenic purpura
- an infection in the bloodstream
Will senile purpura heal over time?
How to get rid of senile purpura?
What causes purpura on legs?
What is the best treatment for HSP?
Henoch-Schonlein purpura usually goes away on its own within a month with no lasting ill effects. Rest, plenty of fluids and over-the-counter pain relievers may help with symptoms.
Can HSP be treated?
Although there is no specific treatment for HSP, you can use over-the-counter pain medicines, such as acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen for joint pain. In some cases, corticosteroid medication may be used.
What triggers HSP?
Nearly half the people who have Henoch-Schonlein purpura developed it after an upper respiratory infection, such as a cold. Other triggers include chickenpox, strep throat, measles, hepatitis, certain medications, food, insect bites and exposure to cold weather.
How do you make HSP go away?
Treatment. Most of the treatment of HSP is aimed at making sure the child is comfortable and has enough fluids to drink. Most often we advise parents to give their children acetaminophen (Tylenol®) or a nonsteroidal anti-inflammatory drug, such as ibuprofen (Motrin® or Advil®) for pain.
Is HSP serious?
Henoch-Schönlein purpura (HSP) affects the blood vessels and causes a spotty rash. It's not usually serious, but can sometimes lead to kidney problems.
Does Covid-19 cause HSP?
12 Looking at both the history and laboratory investigations of this patient, having had no prior infection with the previously mentioned causative organisms, but a prior upper respiratory tract infection with COVID-19, it only suggests that COVID-19 could possibly be an HSP-triggering virus.
Can Covid vaccine trigger HSP?
HSP has previously been reported following immunization with various vaccines, mostly within 12 weeks post vaccination [3]. The aim of this report is to highlight a possible association between COVID-19 vaccination (Pfizer‐BioNTech BNT16B2b2 mRNA vaccine) and first onset of HSP in a previously well adult.
Can HSP affect the brain?
Inflammatory changes associated with HSP can also develop in the joints, kidneys, digestive system, and, in rare cases, the brain and spinal cord (central nervous system). In one form of the disorder, termed Schönlein's purpura, the skin and joints are affected but the gastrointestinal tract is not.
Can HSP recur years later?
About one third of children diagnosed with Henoch-Schönlein purpura will develop recurrent symptoms of Henoch-Schönlein purpura, although most recurrent episodes are less severe than the initial episode. However, recurrent episodes of Henoch-Schönlein purpura can last up to a year after the initial diagnosis.
Why do children get HSP?
The cause of HSP is unknown, but it is most commonly triggered by a viral illness (e.g. a cold), and it occurs most often in the spring. HSP usually affects children from two to 10 years of age, but it can happen in anyone. HSP itself is not contagious, but the infection that has triggered HSP may be contagious.
Who Gets Henoch-Schönlein Purpura (The “Typical” Patient)?
Usually, HSP affects a child shortly after an upper respiratory infection has resolved.HSP is the most common form of vasculitis in children, with...
What Causes Henoch-Schönlein Purpura?
In two-thirds of the cases, the disease follows an upper respiratory tract infection, with onset an average of ten days after the start of respirat...
How Is Henoch-Schönlein Purpura Diagnosed?
Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthri...
Treatment and Course of Henoch-Schönlein Purpura
NSAIDs may alleviate arthralgias but can aggravate gastrointestinal symptoms, and should be avoided in any patient with renal disease. Dapsone (100...
What is the best treatment for HSP?
Although there is no specific treatment for HSP, you can use over-the-counter pain medicines, such as acetaminophen or nonsteroidal anti-inflammatory drugs ( NSAIDs ), such as ibuprofen and naproxen for joint pain. In some cases, corticosteroid medication may be used.
What is the diagnosis of HSP?
The diagnosis of HSP may be clear when the typical rash, arthritis, and abdominal pain are present. A doctor may order some tests to rule out other diagnoses, confirm the diagnosis, and assess its severity.
How long does it take for HSP to end?
Adults with HSP are more likely to have more severe disease compared to children. HSP usually ends after four to six weeks -- sometimes with recurrence of symptoms over this period, but with no long-term consequences (recurrences are fairly common).
How do you know if you have HSP?
The main symptom is a rash with numerous small bruises, which have a raised appearance, over the legs or buttocks. Although HSP can affect people at any age, most cases occur in children between the ages of 2 and 11. It is more common in boys than girls.
What is HSP associated with?
Some experts also say that HSP is associated with the colder weather of fall and winter.
What are the symptoms of HSP?
Here are some key details about the symptoms of HSP: Rash. The rash usually appears in all patients with HSP. The initial appearance may resemble hives, with small red spots or bumps on the lower legs, buttocks, knees, and elbows.
What is Henoch-Schonlein purpura?
Henoch-Schonlein Purpura Diagnosis and Treatment. Henoch-Schonlein purpur a (HSP) is a disease involving inflammation of small blood vessels. It most commonly occurs in children. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start leaking. The main symptom is a rash with numerous small bruises, ...
What is HSP in children?
Henoch-Schönlein purpura (HSP) is a form of vasculitis, a condition that involves inflammation of the blood vessels. It can affect any organ of the body. HSP is the most common form of vasculitis in childhood and affects about 20 in 100,000 children. It occurs most commonly in children ages 2-6, although it can occur at any age.
How long does Henoch-Schönlein purpura last?
However, recurrent episodes of Henoch-Schönlein purpura can last up to a year after the initial diagnosis.
What are the symptoms of Henoch-Schönlein purpura?
Henoch-Schönlein purpura is usually diagnosed based on the presence of several symptoms. These include: 1 Palpable purpura: hemorrhage (bleeding) into the skin or mucous membranes and other tissues 2 Abdominal pain 3 Kidney disease 4 Arthritis
What are the symptoms of purpura?
Common symptoms include: Purpura: hemorrhage (bleeding) into the skin, mucous membranes and internal organs. Pain and inflammation of the joints. Abdominal pain. Gastrointestinal bleeding at any place along the GI tract — mouth, esophagus, stomach or intestines. Inflammation of the kidneys (nephritis)
What is palpable purpura?
Palpable purpura: hemorrhage (bleeding) into the skin or mucous membranes and other tissues. Abdominal pain . Kidney disease. Arthri tis. A platelet count should be obtained in cases of suspected HSP to ensure that it is normal.
Does Henoch-Schönlein purpura require treatment?
Patients with Henoch-Schönlein purpura develop a characteristic bruise-like rash on their arms and/or legs. In most cases, the condition does not require treatment; it will resolve on its own and the child will recover completely. However, some children with Henoch-Schönlein purpura will develop arthritis and abdominal pain.
Can Henoch-Schönlein purpura cause preeclampsia?
Women with a history of Henoch-Schönlein purpura, regardless of prior kidney involvement, are at increased risk to develop preeclampsia during pregnancy. In rare cases, HSP can lead to permanent damage to the kidneys, which may require life-long management by a nephrologist. Reviewed by Lehn Weaver, MD, PhD.
How old is a child with HSP?
The mean age of patients with HSP is 5.9 years.
Who was the first person to have HSP?
Dr. William Heberden, a London physician, described the first cases of Henoch-Schönlein purpura (HSP) in 1801. In describing HSP, Heberden wrote of a 5-year old boy who “…was seized with pains and swellings in various parts…He sometimes had pains in his belly with vomiting…and the urine was tinged with blood. ...
Why is purpura not a hallmark of HSP?
Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis.
How long does it take for HSP to appear?
In two-thirds of the cases, the disease follows an upper respiratory tract infection, with onset an average of ten days after the start of respiratory symptoms . Despite this association, no single microorganism or environmental exposure has been confirmed as an important cause of HSP.
Is HSP self-limited?
HSP is usually self-limited. Therefore, treatment is not indicated in all cases, and full recovery is the rule. HSP is more common in children than adults, but has a tendency to be more severe when it occurs in adults. In a small minority of cases, HSP can cause severe kidney or bowel disease.
Can HSP cause permanent kidney damage?
Adults are more prone to permanent kidney damage. However, patients can take some comfort in knowing that fewer than 5% of patients with HSP develop progressive renal insufficiency. HSP can be mimicked by other forms of systemic vasculitis that are more often life-threatening.
Can HSP cause renal insufficiency?
In many fewer cases, primarily in adults, HSP can progress from hematuria (blood in the urine) to renal insufficiency (decreased kidney function). HSP patients who experience this symptom should be followed more closely, with regular testing of their urine for blood and protein.
What tests can help diagnose HSP?
Tests like these can help diagnose HSP and rule out other diseases with similar symptoms: Blood tests . These can evaluate white and red blood cell counts, inflammation, and kidney function. Urine test. The doctor may check for blood or protein in your urine, a sign that your kidneys have been damaged. Biopsy.
Why does HSP cause rash?
HSP causes inflammation in small blood vessels. As the blood vessels become inflamed, they can leak blood into the skin, which causes the rash. Blood can also leak in the abdomen and kidneys. HSP appears to be caused by an overactive response of the immune system.
How many cases of HSP are there in children?
More than 90 percent of HSP cases are in children, especially those between the ages of 2 and 6. The disease tends to be milder in kids than in adults. Adults are more likely to have pus-filled sores in their rash. They also get kidney damage more often with the condition.
How long does it take for Henoch-Schönlein to go away?
You don’t usually need to treat Henoch-Schönlein purpura. It will go away on its own within a few weeks. Rest, fluids, and over-the-counter pain relievers such as ibuprofen or acetaminophen can help you or your child feel better.
Is HSP contagious?
These infections might trigger the immune system to overreact and release antibodies that attack the blood vessels. HSP itself isn’t contagious, but the condition that started it can be catching.
Can Henoch-Schönlein purpura reoccur?
Most of the time, Henoch-Schönlein purpura gets better on its own within a month. However, the disease can reoccur. HSP can cause complications. Adults can develop kidney damage that may be severe enough to require dialysis or a kidney transplant. Rarely, a section of the bowel can collapse in on itself and cause a blockage.
What increases your risk for HSP?
What increases my risk for HSP? Viral or bacterial infections such as measles, chickenpox, or strep throat. Certain vaccines such as the flu vaccine. Certain medicines such as antibiotics or aspirin. Allergies to insect bites, chocolate, milk, or wheat. Living in cold weather. A family history of HSP.
How to treat a swollen thigh?
Apply ice on your joints for 15 to 20 minutes every hour or as directed. Use an ice pack, or put crushed ice in a plastic bag. Cover it with a towel. Ice helps prevent tissue damage and decreases swelling and pain. Apply heat on your joints for 20 to 30 minutes every 2 hours for as many days as directed.
How to reduce swelling in joints?
Apply heat on your joints for 20 to 30 minutes every 2 hours for as many days as directed. Heat helps decrease pain. Elevate your joint above the level of your heart as often as you can. This will help decrease swelling and pain. Prop your joint on pillows or blankets to keep it elevated comfortably.
How to keep joint elevated?
Prop your joint on pillows or blankets to keep it elevated comfortably. Drink plenty of liquids as directed. Liquids help prevent dehydration from vomiting or diarrhea. Ask how much liquid to drink each day and which liquids are best for you. Rest as directed to help your body heal.
Does HSP go away?
There is no treatment for HSP. HSP may eventually go away or become a chronic condition. You may need medicine to manage your symptoms. This may include medicine to decrease swelling, pain, or fever. It may also include medicine to stop your immune system from attacking your blood vessels.
Can HSP cause kidney failure?
Your kidneys may be damaged if HSP attacks the blood vessels in your kidneys. The damage may get better with treatment or may lead to kidney failure. HSP may cause your bowel to fold into itself and become blocked. You may need surgery to fix this problem.
How to help an HSP cope with stress?
Getting enough sleep, eating a healthy diet, limiting caffeine and alcohol, and planning for decompression time can all be useful strategies. Talking to a friend or therapist can also help an HSP cope with heightened emotional responses to stress.
What does an HSP feel like?
Created with Sketch. HSPs feel as if they register more details of their environment than less sensitive people do—including sounds, sights, or emotional cues. Though such stimuli can feel overwhelming, modifying the environment to suit their needs can be empowering.
Is there a treatment for high sensitivity?
There is no specific treatment recommended for high sensitivity, as it is conceptualized as a personality trait rather than a disorder. However, since the trait often comes with emotional or interpersonal challenges—and may co-occur with anxiety and depression —HSPs may find talk therapy useful for their overall well-being.
Is a HSP shy?
Yes. In fact, though high sensitivity more often overlaps with introversion, Aron argues that as many as 30 percent of HSPs are actually extroverted —though they may still be perceived by others as shy.
