
What is a calcified spleen?
As part of the disease-fighting lymphatic system, the spleen is an important, but not vital, organ. Abnormal calcifications are often seen in the spleen, particularly in the elderly.
What does it mean when something is calcified?
When something is referred to as “calcified,” it means that it contains deposits of the element calcium. Calcium has a tendency to collect in tissue that is healing.
What is a calcified lesion on a splenic artery?
Calcified lesion corresponds to splenic artery pseudoaneurysm according to typical location and imaging characteristics. The differential diagnosis for a splenic artery aneurysm includes an enhancing pancreatic mass or a tortuous vessel.
What is a solitary lesion with calcifications?
Solitary lesions are usually hypo- or isoattenuating with areas of necrosis and rarely have calcifications [ 41, 44 ]. However, when present, calcifications can be dystrophic and de novo ( Fig. 6C) or, after treatment, secondary to necrosis, hemorrhage, or fibrosis [ 12 ].

What is the treatment for calcification?
Treatment. People with painless joint or tendon calcification typically do not need treatment. No treatments can remove calcium deposits from the cartilage of the joints, so doctors tend to rely on glucocorticoid injections, oral colchicine, and NSAIDs to relieve any pain and underlying inflammation.
What does it mean if your spleen is calcified?
Calcification in the spleen usually occurs in small zones, not infrequently in the capsule, occasionally in small infarcts, and at times in tuberculous or gummatous masses. It may occur in thrombosis of the splenic vein or in an echinococcus cyst.
Can you fix calcification?
Most cases of calcific tendonitis can be treated without surgery. Your doctor may recommend a course of physical therapy and over-the-counter (OTC) pain relievers. If the pain and swelling are more severe, they may suggest that you have a corticosteroid (cortisone) injection given in the office.
How are calcified granulomas treated?
Since calcified granulomas are almost always benign, they typically don't require treatment. However, if you have an active infection or condition that's causing granuloma formation, your doctor will work to treat that.
What is the most common cause of splenic calcifications?
Calcified splenic granulomas are a common incidental finding, most commonly resulting from tuberculosis or histoplasmosis and less commonly from Pneumocystis carinii pneumonia or brucellosis [29, 30].
Are splenic calcifications normal?
Calcifications of the spleen are common and usually benign. Calcifications may be punctate, curvilinear or diffuse. Punctate splenic calcifications are typically the sequela of healed infection/inflammation.
What foods reduce calcification?
Bananas and avocados -- foods that are rich in potassium -- may help protect against pathogenic vascular calcification, also known as hardening of the arteries.
Can vitamin D cause calcification of arteries?
Experimental studies have shown that excessive vitamin D activities can induce vascular calcification, and such vascular pathology can be reversed by reducing vitamin D activities. The human relevance of these experimental studies is not clear, as vitamin D toxicity is relatively rare in the general population.
What are the symptoms of calcification?
Symptoms of calcificationBone pain.Bone spurs (occasionally visible as lumps under your skin)Breast mass or lump.Eye irritation or decreased vision.Impaired growth.Increased bone fractures.Muscle weakness or cramping.New deformities such as leg bowing or spine curvature.More items...
What causes granulomas in the spleen?
Splenic granulomas present as single or multiple hypodense lesions on CT. These lesions are usually caused by M. tuberculosis infection and very rarely due to MAC. Splenic granulomas may be seen in association with disseminated MAC infections.
How do you treat granulomas?
Treatment options include:Corticosteroid creams or ointments. Prescription-strength products may help improve the appearance of the bumps and help them disappear faster. ... Corticosteroid injections. ... Freezing. ... Light therapy. ... Oral medications.
Are calcified granulomas permanent?
Over time, granulomas can become calcified or bone-like, and cause permanent damage. Because it can affect any organ, or multiple organs at the same time, sarcoidosis takes on different forms.
What is calcification in the body?
What is calcification? Calcification is a gradual accumulation of calcium in an area of your body tissue. Most of the calcium absorbed by your body ends up in your bones and teeth, where it is most needed.
What does a calcification on a mammogram mean?
Calcifications that are apparent on mammograms may signal the presence of breast cancer, or they may occur with benign breast disease.
What is calcification in musculoskeletal disease?
Calcification can be part of a normal healing response to musculoskeletal injuries. Calcifications are often found in arteries affected by arteriosclerosis (hardening of the arteries), in benign and malignant breast processes, at sites of bone or cartilage injury, and sometimes within cancers.
What are the symptoms of calcification?
At times, any of these symptoms can be severe: Bone pain. Bone spurs (occasionally visible as lumps under your skin) Breast mass or lump. Eye irritation or decreased vision.
Why is my calcium level abnormal?
Sometimes blood calcium levels become abnormal, signaling the presence of a metabolic disorder in which your body’s ability to use or regulate the level of calcium is compromised. Seek immediate medical care (call 911) for serious symptoms, such as severe headache, severe bone pain, or sudden abdominal, pelvic, or lower back pain.
Is calcification a serious condition?
In some cases, calcification can be part of a serious condition that should be immediately evaluated in an emergency setting. Seek immediate medical care (call 911) if you, or someone you are with, have complications of calcification, including kidney stones, Paget’s disease (abnormal bone tissue loss and reformation), pineal gland tumors, or severe hypercalcemia (excess calcium in the blood), and experience any of these serious symptoms including:
Can calcification be detected on X-rays?
Instead, calcification is most frequently discovered on X-rays, including mammograms, for example. Some calcification is normal, but even disease-related calcification may not cause symptoms that you will detect. You may, however, feel the effects of the underlying disorder or process that results in calcification.
How to diagnose calcification?
Diagnosing calcification. Calcifications are usually found via X-rays. X-ray tests use electromagnetic radiation to take pictures of your internal organs and usually cause no discomfort. Your doctor will likely detect any calcification issues right away with X-rays. Your doctor may also order blood tests.
What causes calcification in the body?
Causes of calcification. Many factors play a role in calcification. These include: infections. calcium metabolism disorders that cause hypercalcemia (too much calcium in the blood) genetic or autoimmune disorders affecting the skeletal system and connective tissues. persistent inflammation.
What are the soft tissues that are affected by calcium buildup?
soft tissues like breasts, muscles, and fat. kidney, bladder, and gallbladder. Some calcium buildup is harmless. These deposits are believed to be the body’s response to inflammation, injury, or certain biological processes. However, some calcifications can disrupt organ function and affect blood vessels.
What happens when calcium builds up in the body?
Calcification happens when calcium builds up in body tissue, blood vessels, or organs. This buildup can harden and disrupt your body’s normal processes. Calcium is transported through the bloodstream. It’s also found in every cell. As a result, calcification can occur in almost any part of the body. According to the National Academy of Medicine. ...
What is the most common type of breast calcification?
According to the National Cancer Institute, macrocalcifications in the breasts are most common in women over 50 years old.
What medications affect calcium levels?
Some medications can affect your body’s calcium levels. Cholesterol medication, blood pressure medication, and hormone replacement therapy are common medications that affect how calcium is used in your body.
Can you get calcifications at 65?
If you’re under 65 years old and were born with a heart defect or kidney-related issues, calcifications can be more common for you than for others of your age. If you are aware of any of these conditions, ask your doctor about getting tested for calcifications. Some medications can affect your body’s calcium levels.
How to treat brain calcification?
Some treatment options for dystonia include: physical therapy. speech and voice therapy. relaxation and stress management.
When does calcification start?
Artery calcification. Artery calcification can start at a young age , but a doctor may only notice it once the deposit is large enough to appear in an imaging scan. Artery calcification at a detectable level typically occurs in adults over 40 years of age. Trusted Source.
What causes calcification in the joints?
Calcium pyrophosphate dihydrate crystal disease is often the cause of joint calcification. In fact, research suggests that around 45%#N#Trusted Source#N#of people aged 85 and over have calcium deposits in the cartilage of their joints.
What is it called when you have calcium in your urine?
Calcium deposits can also form in the kidneys. This is called nephrocalcinosis. People with nephrocalcinosis may also have high levels of calcium or phosphate in their blood or urine. Doctors classify nephrocalcinosis as molecular, microscopic, or macroscopic.
What causes kidney calcification?
Kidney calcification can develop due to vitamin D therapy, primary hyperparathyroidism, or sarcoidosis, among other things. Treatment will depend and focus on the cause.
Why do people not know they have calcification?
People may not know they have calcification because it does not always cause any symptoms. Some types of calcification are irreversible, but depending on the type, there may be ways to reduce pain and lower the risk of complications. Last medically reviewed on January 27, 2020. Biology / Biochemistry.
Where does calcification occur in the brain?
Brain calcification. Primary familial brain calcification occurs when abnormal calcium deposits form in the blood vessels in the brain. These deposits typically form in the basal ganglia, which initiate and control bodily movement.
What type of cyst is calcified with dead scolexes?
Type III cysts may be densely calcified with dead scolexes [ 3, 33, 34 ]. Type IV cysts are associated with parasitic membrane degeneration that leads to fissures in the cyst wall and rupture of the cyst with superinfection in 50% of cases because of pleural, peritoneal, or biliary seeding [ 33 ].
Is angiography invasive?
Angiography is the diagnostic method reference standard; however, it is invasive [ 58 ]. On angiography, half of aneurysms are fusiform and half are saccular, with greater incidence of pancreatitis when saccular [ 58 ]. Splenic artery aneurysms are related with a risk of rupture in 2% of cases [ 56 ]. Conclusion.
Is a splenic mass benign?
A study by Siewert et al. [ 1] found that among incidentally discovered splenic masses greater than 1 cm in diameter, 84% were benign and 16% were malignant.
Can a splenic lesion be a granuloma?
Incidental splenic lesions, often found on CT images of the abdomen, may often be ignored or mischaracterized. Calcified splenic lesions are often presumed to be granulomas; however, understanding the broader differential diagnostic considerations can be useful. CONCLUSION.
What is a calcified granuloma?
Overview. A calcified granuloma is a specific type of tissue inflammation that has become calcified over time. When something is referred to as “calcified,” it means that it contains deposits of the element calcium. Calcium has a tendency to collect in tissue that is healing. The formation of granulomas is often caused by an infection.
Do granulomas calcify?
Not all granulomas are calcified. Granulomas are made up of a spherical cluster of cells that surrounds the inflamed tissue. They can eventually calcify over time. A calcified granuloma has a similar density to bone and will appear more brightly than the surrounding tissue on an X-ray.
Can a calcified granuloma be treated?
If you’re diagnosed with a calcified granuloma, the granuloma itself will likely not require treatment. If you have an underlying condition or infection that’s leading to granuloma formation, your doctor will work to treat that. The individual outlook is dependent on the condition being treated.
What is calcified granuloma?
Calcified granuloma is granuloma (small area of inflammation) that has become calcified over time. A granuloma is a pathological term defined as a collection of macrophages and then maturation into epithelioid cells that attempt to wall off the antigenic but indigestible substance 1). Granulomas are formed by the process ...
What causes calcification in the lungs?
Tuberculosis (TB) is a common cause of intrathoracic calcifications. Most calcific deposits in TB are dystrophic and may present as parenchymal granulomas, mediastinal lymph nodes, and fibronodular areas of lung involvement (Figure 2). Diffuse nodular calcification of the lungs may be the result of a hematogenous infection .
What causes a calcified lung nodule?
The most common cause of lung nodule calcification is granuloma formation, usually in the response to healed infection. Healed infection. calcified granulomata, e.g. thoracic histoplasmosis, recovered miliary tuberculosis (rare) most common. 2-5 mm. calcification may be central or diffuse.
Is hypercalcemia secondary to granulomatous infections?
Hypercalcemia secondary to granulomatous infections or supplemental vitamin D is a rare occurrence but may contribute to calcification of intrathoracic granulomas 9). Calcified lung granulomas secondary to Coccidioides immitis infection is a rare occurrence.

Types
- Two types of pathologic (abnormal) calcifications can affect the spleen. "Dystrophic calcification" refers to mineral deposition in dying tissues, in spite of normal blood calcium levels. "Metastatic calcification" describes the deposition of calcium salts in normal tissues, usually in the presenc…
Spleen Features
- Located just under the left side of the rib cage, the spleen is a spongy, fist-sized organ. It is covered with a fibrous capsule and is comprised of a white pulp and a red pulp.
Spleen Function
- The white pulp of the spleen helps the body fight infections by producing white blood cells called lymphocytes, The main role of the red pulp is to filter the blood to remove unwanted substances.
Infectious Causes
- • Histoplasmosis, caused by the soil fungus Histoplasma Capsulatum • Brucellosis, caused by bacteria of the genus Brucella • Tuberculosis (TB), caused by Mycobacterium tuberculosis • Candidiasis (yeast infection) in immunocompromised patients • Pneumocystis infection, especially Pneumocystis carinii • Parasitic cystscause: 1. • Histoplasmosis 2. caused by the soil …
Other Causes
- Calcification may occur in the parenchyma, or essential tissue, of the spleen. Possible causes include: • Phleboliths (stony deposits in veins) • Hemangioma (benign blood vessel tumor) • Splenic lymphoma (lymph tissue cancer) • Hematoma (mass of clotted blood in tissue or organ) Diffuse uniform calcification can result from impaired blood flow to the spleen and tissue death …