Treatment FAQ

postrate cancer what to expect when treatment has done no good

by Ms. Cristal Olson Published 2 years ago Updated 2 years ago

If left untreated, however, prostate cancer can proceed on a number of different paths. If left untreated, diagnosed prostate cancer can grow and possibly spread outside of the prostate to local tissues or distantly to other sites in the body.

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What happens if cancer comes back after treatment?

If the cancer has spread outside the prostate, it will most likely go to nearby lymph nodes first, and then to bones. Much less often the cancer will spread to the liver or other organs. When prostate cancer has spread to other parts of the body (including the bones), hormone therapy is probably the most effective treatment. But it isn’t likely to cure the cancer, and at some point it might …

What to do if cancer recurrence is not clear?

May 13, 2019 · Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing. If this happens, your doctor might say your cancer has advanced or progressed. There may or may not be other treatment options. But when many different treatments have been …

When is it time to stop trying new treatments for cancer?

Jul 13, 2018 · This is called "local disease" or "localized disease." The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative and completely kill or remove whatever cancer cells are present. If left untreated, however, prostate cancer can proceed on a number of different paths.

What to do if prostate cancer doesn't go away?

Your prostate-specific antigen (PSA) levels should get very low after treatment, but PSA results aren't always cut and dry. Learn more here. Following PSA Levels During and After Prostate Cancer Treatment The American Cancer Society is here to support Ukrainian patients with cancer, caregivers, and clinicians. Close Critical Alert Banner

How long can you live with incurable prostate cancer?

The researchers demonstrated that a patient with incurable, castration-resistant prostate cancer receiving a novel targeted therapy will live for around 41 months – just under three-and-a-half years – on average. This is up from an average of 13-16 months on average in the era before docetaxel-based chemotherapy.Jul 30, 2013

What happens when hormone therapy stops working for prostate cancer?

Most prostate cancers eventually stop responding to hormone therapy and become castration (or castrate) resistant. That is, they continue to grow even when androgen levels in the body are extremely low or undetectable.Feb 22, 2021

What happens when prostate cancer progresses?

With advanced disease, mainly if you have not had treatment to the prostate itself, you may have problems passing urine or see blood in your urine. Some men may feel tired, weak or lose weight. When prostate cancer spreads to bones, you may have bone pain.

What happens if you don't do anything about prostate cancer?

If left untreated, diagnosed prostate cancer can grow and possibly spread outside of the prostate to local tissues or distantly to other sites in the body. The first sites of spread are typically to the nearby tissues.Jan 24, 2022

How long can a man stay on hormone therapy for prostate cancer?

Hormone therapy can help shrink the prostate and any cancer that has spread, and make the treatment more effective. You may be offered hormone therapy for up to six months before radiotherapy. And you may continue to have hormone therapy during and after your radiotherapy, for up to three years.

Does a high PSA mean cancer has spread?

In most cases, a higher PSA level indicates a poorer prostate cancer prognosis. PSA is a protein made by prostate tissue. Men with prostate cancer often have elevated PSA levels because the cancer cells make excessive amounts of this protein.

What are the signs that prostate cancer has spread?

Prostate cancer can spread to the lymph nodes in the groin area, or to other parts of the body. The most common symptoms are swelling and pain around the area where the cancer has spread. Cancer cells can stop lymph fluid from draining away. This might lead to swelling in the legs due to fluid build up in that area.

What are the symptoms of the last stages of prostate cancer?

Signs and symptoms of stage 4 prostate cancer may include:
  • Painful urination.
  • Decreased force in the stream of urine.
  • Blood in the semen.
  • Bone pain.
  • Swelling in the legs.
  • Fatigue.
May 8, 2020

How do you know if prostate cancer is aggressive?

PSA levels are determined by a simple blood test. The higher the number, the more likely the patient is to have prostate cancer. PSA velocity. Several studies indicate that when PSA levels increase sharply, the cancer is likely to be aggressive.Jul 28, 2020

Where is the first place prostate cancer spreads to?

If prostate cancer spreads to other parts of the body, it almost always goes to the bones first. These areas of cancer spread can cause pain and weak bones that might break.Dec 10, 2020

How fast does prostate cancer usually spread?

Prostate cancer is a slow-growing cancer and, more often, it is confined to the prostate gland, requiring minimal or no treatment. In some cases, it can take up to eight years to spread from the prostate to other parts of the body (metastasis), typically the bones.Apr 16, 2021

How long can you wait to have prostate surgery?

"Our study suggests that waiting up to six months to have surgery does not negatively impact a low-risk patient's chance of cure," says Duke University Medical Center urologist and surgeon Stephen Freedland, MD.Mar 9, 2006

What to do after radical prostatectomy?

After surgery: If you’ve had a radical prostatectomy, radiation therapy might be an option, sometimes along with hormone therapy. After radiation therapy: If your first treatment was radiation, treatment options might include cryotherapy or radical prostatectomy, but when these treatments are done after radiation, ...

Does prostate cancer come back?

Prostate cancer often grows slowly, so even if it does come back, it might not cause problems for many years, at which time further treatment could then be considered. Factors such as how quickly the PSA is going up and the original Gleason score of the cancer can help predict how soon the cancer might show up in distant parts ...

What is castrate resistant prostate cancer?

Castrate-resistant and hormone-refractory prostate cancer 1 Castrate-resistant prostate cancer (CRPC) is cancer that is still growing despite the fact that hormone therapy (an orchiectomy or an LHRH agonist or antagonist) is keeping the testosterone level in the body as low as what would be expected if the testicles were removed (called castrate level s). The cancer might still respond to other forms of hormone therapy, though. 2 Hormone-refractory prostate cancer (HRPC) is cancer that is no longer helped by any form of hormone therapy.

Where does prostate cancer go?

If the cancer has spread outside the prostate, it will most likely go to nearby lymph nodes first, and then to bones. Much less often the cancer will spread to the liver or other organs. When prostate cancer has spread to other parts of the body (including the bones), hormone therapy is probably the most effective treatment.

Can prostate cancer be treated with hormones?

Much less often the cancer will spread to the liver or other organs. When prostate cancer has spread to other parts of the body (including the bones), hormone therapy is probably the most effective treatment. But it isn’t likely to cure the cancer, and at some point it might stop working.

Does hormone therapy help with prostate cancer?

Hormone therapy is often very effective at shrinking or slowing the growth of prostate cancer that has spread , but it usually becomes less effective over time. Doctors use different terms to describe cancers that are no longer responding to hormones.

What is CRPC prostate cancer?

Castrate-resistant prostate cancer (CRPC) is cancer that is still growing despite the fact that hormone therapy (an orchiectomy or an LHRH agonist or antagonist) is keeping the testosterone level in the body as low as what would be expected if the testicles were removed (called castrate level s). The cancer might still respond to other forms ...

Does cancer stop working?

If Cancer Treatments Stop Working. Cancer treatments can help stop cancer from growing or spreading. But sometimes treatment does not work well or stops working. Maybe treatment ended a while ago and was successful at first, but cancer has come back. Or maybe one type of cancer treatment has stopped working and the cancer has kept growing.

Can you get a second opinion on cancer?

When faced with deciding whether to continue cancer treatment, some patients or their loved ones may want to get a second opinion. Even when you place full trust in your doctor and cancer care team, you might wonder if another doctor could offer something else or more information. It's normal to think about talking to someone else, and your doctor should support you if you decide to get another opinion. Remember that your cancer care team wants you to be sure about the decisions you make. You can read more in Seeking a Second Opinion.

How to talk to your loved ones about cancer?

Talking with your loved ones. Be open with your loved ones about your cancer and the news you've been given. Explore their thoughts, feelings, and suggestions. Talk to them about the options you have been given, along with the decisions you have made or are thinking of making. If you feel you need their input, ask.

Can cancer shrink?

If you have cancer that keeps growing or comes back after one kind of treatment, it’s possible that another treatment might still help shrink the cancer, or at least keep it in check enough to help you live longer and feel better. Clinical trials also might offer chances to try newer treatments that could be helpful.

Can palliative care be used for cancer?

Be sure to ask about and get treatment for any symptoms you might have, such as nausea or pain. Palliative care can be used whether you are getting cancer treatment or not. And it can be used at any stage of your illness. Palliative care is used to help ease symptoms and side effects.

What does hospice care mean?

Hospice care treats the person rather than the disease; it focuses on the quality of your life rather than its length. While getting hospice care means the end of treatments such as chemo and radiation, it doesn’t mean you can’t have treatment for the problems caused by your cancer or other health conditions.

What is the best treatment for prostate cancer?

Once the cancer has spread distantly from the prostate, it becomes far harder to effectively treat and completely cure. Chemotherapy and hormone therapy become the most feasible options because they treat cancer throughout the body.

Can radiation kill prostate cancer?

The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative and completely kill or remove whatever cancer cells are present. But let's take a look at the natural history of prostate cancer if it is not treated...

Can a doctor monitor prostate cancer?

Instead, they may choose to have their doctors monitor their cancer, especially if it's expected to grow slowly based on biopsy results, confined to the prostate, not causing any symptoms, and/or small. This is called active surveillance, meaning doctors will initiate cancer treatment only if the cancer starts growing.

Is prostate cancer confined to the prostate?

With regard to prostate cancer, most cases of the disease are discovered while the cancer is still confined to the prostate itself. This is called "local disease" or "localized disease.". The disease is easiest to treat while it is confined to the prostate.

What is localized prostate cancer?

This is called "local disease" or "localized disease.". The disease is easiest to treat while it is confined to the prostate. At this stage, surgery and radiation are most likely to be curative and completely kill or remove whatever cancer cells are present.

Can prostate cancer spread to other parts of the body?

Most cases of diagnosed prostate cancer, however, if left untreated, will grow and possibly spread outside of the prostate to local tissues or distantly to other sites in the body. The first sites of spread are typically to the nearby tissues.

Can prostate cancer cause death?

In fact, some studies have shown that prostate cancer is present in the majority of older men at the time of their deaths even if they had not been diagnosed. This suggests that many older men have prostate cancer that is small and slow-growing, but the disease causes them few symptoms and does not lead to their death.

How long does it take for a PSA to drop after a prostatectomy?

Your PSA should fall to a very low or even undetectable level within a couple of months after radical prostatectomy. Because some PSA can remain in the blood for several weeks after surgery, even if all of the prostate cells were removed, doctors often advise waiting at least 6 to 8 weeks after surgery before checking the PSA level.

Can you detect PSA after surgery?

Some men might worry if their PSA is still detectable even at a very low level after surgery, but this does not always mean cancer is still in the body. Modern PSA blood tests can detect even tiny amounts of PSA, but these amounts might not always be significant, especially if they are not rising over time.

Does radiation kill prostate cells?

Radiation therapy doesn’t kill all of the cells in the prostate gland, so it's not expected to cause the PSA to drop to an undetectable level. The remaining normal prostate cells will still make some PSA.

Why is PSA important for prostate cancer?

When treatments such as hormone therapy, chemotherapy, or immunotherapy are used for more advanced prostate cancer, the PSA level can help show how well the treatment is working or when it might be time to try a different treatment.

Is a low PSA blood test good?

Generally speaking, your PSA level should get very low after treatment. But PSA results aren’t always reliable, and sometimes doctors aren’ t sure what they mean.

Why is PSA monitored?

If you choose observation or active surveillance, your PSA level will be monitored closely (most likely along with other tests) to help decide if the cancer is growing and if treatment should be considered. Your doctor will watch your PSA level and how quickly it is rising.

Can a doctor check your PSA?

Your doctor will watch your PSA level and how quickly it is rising. Not all doctors agree on exactly what PSA level might require further action (such as a prostate biopsy or treatment). Again, talk to your doctor so you understand what change in your PSA might be considered cause for concern.

What is a follow up appointment for prostate cancer?

This is often called follow-up. The aim of your follow-up appointments is to: check how your cancer has responded to treatment. help you deal with any side effects of treatment.

How long does it take for a prostate to drop?

PSA level after radiotherapy or brachytherapy. After radiotherapy or brachytherapy, your PSA should drop to its lowest level (nadir) after 18 months to two years.

Can prostate cancer cause anxiety?

Depression and anxiety. Men with prostate cancer may get depressed before or after treatment. Depression can cause a variety of symptoms from feelings of unhappiness and hopelessness, to losing interest in the things you usually enjoy and feeling very tearful. Many people with depression also feel anxious or worried.

Who is your main contact for follow up care?

This might be your specialist nurse, hospital doctor, GP, radiographer or another health professional. They are often called your key worker.

How long before a check up can you get a PSA test?

The PSA test is a blood test that measures the amount of a protein called prostate specific antigen (PSA) in your blood. You will usually have one done a week or two before your appointment, so that the results are available at your check-up. You will be told when to make an appointment for the test. It might be done at your GP surgery or at hospital, depending on the services in your area.

Can you take everything in at an appointment?

It can be hard to take everything in at your appointments. Some people find it helpful to take someone with them, to listen and discuss things with later. If your appointment is on the phone, you could ask a friend or family member to listen with you.

Can side effects affect your life?

Side effects can affect your day-to-day life, but there are treatments for them, as well as things you can do to manage them yourself. It’s important to speak to your doctor, nurse or GP about them.

Can stage IV prostate cancer be cured?

Most stage IV cancers can’t be cured, but are treatable. The goals of treatment are to keep the cancer under control for as long as possible and to improve a man’s quality of life. Treatment of stage IV prostate cancer may also include treatments to help prevent or relieve symptoms such as pain.

Can stage 4 cancer be cured?

Stage IV cancers have already spread to nearby areas such as nearby lymph nodes or to distant organs such as the bones. Most stage IV cancers can’t be cured, but are treatable. The goals of treatment are to keep the cancer under control for as long as possible and to improve a man’s quality of life.

How to treat a swollen intestine?

Initial treatment options may include: 1 Hormone therapy 2 Hormone therapy with chemotherapy 3 Hormone therapy with external beam radiation 4 Chemotherapy 5 Surgery (TURP) to relieve symptoms such as bleeding or urinary obstruction 6 Treatments aimed at bone metastases, such as denosumab (Xgeva), a bisphosphonate like zoledronic acid (Zometa), external radiation aimed at bones, or a radiopharmaceutical such as strontium-89, samarium-153 or radium-223 7 Observation (for those who are older or have other serious health issues and do not have major symptoms from the cancer) 8 Taking part in a clinical trial of newer treatments

How is prostate cancer staged?

Prostate cancer is staged based on the extent (how much the cancer has spread) of the cancer (using T, N, and M categories) and the PSA level and Gleason score (Grade Group) when it is first diagnosed. For prostate cancers that haven't spread (stages I to III), doctors also use risk groups (based on how far the prostate tumor has grown, PSA level, ...

Can prostate cancer be treated with radiation?

For men without any prostate cancer symptoms who are elder ly and/or have other serious health problems that may limit their lifespan, observation or active surveillance is often recommended. For men who wish to start treatment, radiation therapy (external beam or brachytherapy) or radical prostatectomy may be options.

Does stage 2 prostate cancer grow outside the prostate?

Stage II cancers have not yet grown outside of the prostate, but are larger, have higher Gleason scores, and/or have higher PSA levels than stage I cancers. Stage II cancers that are not treated with surgery or radiation are more likely than stage I cancers to eventually spread beyond the prostate and cause symptoms.

What is stage 3 prostate cancer?

Stage III. Stage III cancers have grown outside the prostate and may have reached the bladder or rectum (T4). They have not spread to lymph nodes or distant organs. These cancers are more likely to come back after treatment than earlier stage tumors. Treatment options at this stage may include:

What is the best treatment for cancer?

When your cancer spreads, your doctor will most likely suggest hormone therapy. That usually means taking medication to lower the amount of androgen hormones (testosterone and DHT) in your body or prevent them from affecting cancer cells. A related but rarely used option is surgical castration.

How long does it take to live with prostate cancer?

The 5-year survival rate for prostate cancer that has moved into nearby parts of the body is nearly 100%. Here's what you should know about your treatment and what to expect going forward.

Can prostate cancer affect your life?

Living With Cancer. No matter which treatments you decide to pursue, advanced prostate cancer is bound to take a toll on your day-to-day life. Loss of bladder control (incontinence), fatigue, and erectile dysfunction often go hand-in-hand with treatment.

How do you know if you have prostate cancer?

They might also find it with a digital rectal exam or on an X-ray or other test. If you do have symptoms, they often include trouble peeing or blood in your urine.

Where does prostate cancer show up?

When this type of cancer spreads (your doctor may say it has metastasized), it tends to first show up in the tissues or lymph nodes that are closest to the prostate gland. If it's caught and treated at this point, which is known as "regional" stage, your odds of recovery are very good. If it travels further, the cancer usually ends up in your bones.

Can cancer cause you to feel tired?

You might also feel very tired, short of breath, or lose weight without trying. You’re more likely to feel pain if the cancer has gone into your bones. Where it hurts will depend on which bones it affects. For instance, you might feel hip or back pain if cancer has spread into your pelvic bones.

How do you know if you have cancer in your bones?

They might also find it with a digital rectal exam or on an X-ray or other test. If you do have symptoms, they often include trouble peeing or blood in your urine. You might also feel very tired, short of breath, or lose weight without trying. You’re more likely to feel pain if the cancer has gone into your bones.

When Not Treating "Cancer" Is the Best Treatment Plan

For most people, hearing the word "cancer" is terrifying And now a recent research study indicates that the word may also influence whether people choose treatment. This is important because cancer treatment poses many risks for individuals, not the least of which are treatment-related side effects and long-term effects.

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