The Effect a Drug may have is Dependent on a Variety of Factors: Drug dosage: effect of drug increases with increased amount of drug up to the POINT OF RECEPTOR SATURATION Number of Receptors: receptors may be differentially expressed in one tissue to the next and, therefore, mediate different levels of biological responses.
Full Answer
What factors affect drug dosage and drug effects?
Drug dosage and drug effects are also affected by the type of drug formulation or dosage form. The same drug with same amount through the same route but with different drug dosage formulations may produce varying concentrations of the drug in the system with consequent alterations in response.
What are the factors that influence drug treatment decisions?
Other factors are gender, race, pregnancy, breast feeding, kidney problems, liver function, drug dose and frequency and many other factors. The effect of these factors on ADRs is well documented in the medical literature. Taking these factors into consideration during medical evaluation enables medical practitioners to choose the best drug regimen.
What are the 5 factors that contribute to drug addiction?
What Factors Contribute to Drug Addiction? 1 Genetics. 2 Environment. 3 Trauma. 4 Mental Illness. 5 Peer Pressure.
Why do drug effects vary among species?
Drug effects may vary qualitatively or quantitatively among species due to variations in physiology or pharmacodynamics features (Table 4.3). Characteristic qualitative variations are seen with emetics, morphine and histamine.
What are the factors contributing to drug abuse?
There are certain factors that increase the risk of a person developing an addiction to drugs or alcohol. Genetics, family history, mental health, and the environment are some of the risk factors for addiction susceptibility.
What are 5 factors that influence drug use?
Risk factorsFamily history of addiction. Drug addiction is more common in some families and likely involves genetic predisposition. ... Mental health disorder. ... Peer pressure. ... Lack of family involvement. ... Early use. ... Taking a highly addictive drug.
What are some factors which can influence the effect of a drug on the body?
The individualthe age, gender, weight and general health of the individual and how might this interact with the type of substance being used.the individual's tolerance and previous experience of the substance including intoxication, after effects and withdrawal.More items...
What makes a treatment effective?
To be effective, treatment must address the individual's drug abuse and any associated medical, psychological, social, vocational, and legal problems. It is also important that treatment be appropriate to the individual's age, gender, ethnicity, and culture.
What are four social factors that contribute to substance abuse?
Social Risk Factors. Social factors that contribute to increased risk for adolescent substance use include deviant peer relationships, popularity, bullying, and association with gangs. Social influences and familial influences are often present simultaneously.
What are six social factors that contribute to substance abuse?
Risk factors categorized as familial include childhood maltreatment (abuse and neglect), familial substance abuse, and parent-child relationships. Social risk factors include association with deviant peers, popularity, bullying, and gang affiliation. Individual risk factors include ADHD and depression.
What are the 12 principles for effective drug treatment?
An effective treatment program will address all a person's needs, not just his/her addiction....Effective Treatment Programs Yield Beyond Successful ResultsStop drug and alcohol use and consumption.Remain completely free of drugs and alcohol.Thrive productively at work, in society, and with his/her family.
What is the most effective way to treat drug addiction?
There are many options that have been successful in treating drug addiction, including:behavioral counseling.medication.medical devices and applications used to treat withdrawal symptoms or deliver skills training.evaluation and treatment for co-occurring mental health issues such as depression and anxiety.More items...•
What is the purpose of drug treatment?
Drug treatment is intended to help addicted individuals stop compulsive drug seeking and use. Treatment can occur in a variety of settings, take many different forms, and last for different lengths of time.
What is the problem with drug abuse?
Drug abuse is a severe problem that affects millions of Americans yearly, causing health, mental, and relationship problems.
Why are prescription drugs so addictive?
Prescription Drugs – Prescription drugs present a very high risk factor for drug addiction, simply because many of them are highly addictive. Prescription painkillers, sedatives, antidepressants, and many other types of prescription drugs can easily lead to physical and mental dependence by flooding the dopamine receptors in the brain.
How many times more likely are people with mental disorders to use drugs?
Many persons who have mental disorders are up to three times as likely to use drugs or alcohol recreationally. Peer Pressure – Having friends or loved ones who are addicted to or use drugs recreationally makes it statistically more likely for someone to use them themselves.
How does anxiety affect drug use?
Anxiety and depression both greatly increase the risk factors for starting drugs, but also influence drug use by making the person more susceptible to other risk factors.
Is it the user's responsibility to become an addict?
No one chooses to become an addict which is why it is important to remember that addiction is not the user’s fault. However, it is the user’s responsibility – especially once they realize they are an addict – to seek out help and to get clean. Beginnings Treatment Centers provide modern and effective programs for the treatment ...
Is drug abuse a disease?
Whether you are a drug user, are checking for a friend, or are researching for your own reasons, it’s important to understand that every drug user has their own motivations. Drug abuse is most often considered a disease and blaming someone for their use is never a solution.
Do people who use drugs choose friends?
While some studies correlate the fact that persons who are more likely to use drugs are more likely to choose drug users as friends, others show that the simple desire to keep up appearances with friends does contribute to starting drug use as well as to preventing users from quitting.
What are the factors that affect drug use?
an increased euphoria. a quick involvement with repetitive behaviors, i.e., an addictive personality. These genetic factors can cause experimental drug use to quickly spin out of control and make it difficult to stop. 2) Environment. Studies have shown that genetics alone does not an addict make.
What happens when you live in a neighborhood where drug use is normalized?
It can also be stressful to live in that type of environment, which can lead to addiction by way of numbing the fear and worries one might experience. 3) Trauma.
How does genetics affect addiction?
That being said, genetics do play a role by predisposing you to developing an addiction. According to the American Psychological Association genes are important in addiction - genetic factors contribute to about half of a person's tendency to become addicted. Our genes have been linked to: a quicker reaction to drugs.
Why is it important to keep in mind that just the way a person reacts to or thinks about things can
It is important to keep in mind that just the way a person reacts to or thinks about things can predispose him or her to becoming addicted. For example, someone who is impulsive by nature makes snap decisions without thinking about the consequences or long term effects.
How many children experience trauma?
Studies show that one in four of American children experience at least one of these traumas during childhood. Other exposure to trauma, even after becoming an adult, has been shown to be correlated with an increased chance for addiction as well. 4) Mental Illness.
Can peer pressure affect adults?
While many people associate peer pressure strictly with kids and teenagers, it does manifest itself in adults as well. In that case, the influence is usually surrounding who they live with. Hoping to re-experience that first high, a sober partner may join in and begin to abuse drugs with their spouse.
Does genetics make you an addict?
Studies have shown that genetics alone does not an addict make. Like so many others, the home that you and your siblings grew up in also plays a significant role in your addiction. There are several factors that play into this: Perhaps, your parents stayed together but fought frequently and intensely.
What Are the Signs of Drug Abuse?
Although signs and symptoms of drug use may vary depending on the substance abused, below are several things to look out for. Also, just because a person exhibits any of the below signs is not indicative of definite drug use.
What Are the Factors Contributing to Drug Abuse?
First, it is important to note that not everyone at risk for drug abuse will use drugs or become addicted. Furthermore, a risk factor for one person may not be one for another.
How to Get Help with Drug Abuse
For the best possible outcome of addiction treatment, it is important to find an addiction treatment facility that cares. The compassionate staff at Laguna View Detox understand how important mind-body wellness is in achieving and maintaining sobriety.
What are the factors that determine the absolute dose of a drug?
Genetic Factors 3. Pathological Factors 4. Environmental Factors 5. Therapeutic Factors. Factor # 1. Physiological Factors: i. Species: Absolute dose of a drug varies with species as different species are of different sizes, and the amount of drug has to be in proportion to the size of the target species.
What drugs raise T 1/2?
These organ dysfunctions in neonates and geriatic animals tend to raise t 1/2 of most drugs; particularly those requiring hepatic inactivation (salicylate, pentobarbitone and chloramphenicol) or renal excretion (penicillin-G, ampicillin and oxytetracycline) or both (trimethoprim, sulfadoxine and sulfadimethoxine).
Why is pentobarbitone long acting?
For example, pentobarbitone is long-acting (20 hours or more) in young calves than adult cattle (t 1/2 0.8 hr) due to deficient hepatic oxidative microsomal system.
What is the rhythm of a drug?
Circadian (Latin: circa = about; diem = day) rhythm s occur in many physiological and many biochemical functions that alter drug dosage and drug effect. This includes variations in hepatic drug metabolizing enzymes, altered neuronal activity, altered drug distribution or even changes in hormonal profiles and in central receptor density.
How does ambient temperature affect pharmacokinetics?
Drug effects including toxicity can vary with seasons, ambient temperature and with change in altitude. High altitude with low atmospheric pressure reduces the potential of body to oxidize drugs, as low oxygen is available in the system.
What is the physiological parameter that changes with age in total body water?
Another physiological parameter that changes with age in total body water; it is greater in newborns (86-70%) that in adults (58-55%). Accordingly, water soluble drugs have to be given in decreasing dose rates with advancing with postnatal age. The decline in total body water continues into old age.
How sensitive is a man to drugs?
Generally, man is assumed to be six times as sensitive as dog, and ten times as sensitive as rat to the drug effects. Domestic animals too exhibit varying sensitivity to some drugs (Table 4.1) therefore, dose rates vary with species.
What are the factors that influence drug use?
Common Factors that influence drug use. Anyone from any social status, background, race, or gender can become an addict. However, there’s scientific evidence proving that certain people have higher risk factors for substance abuse than others. Many factors increase the risk of a person becoming addicted to drugs.
What are the factors that increase the risk of addiction?
Many factors increase the risk of a person becoming addicted to drugs. Factors such as family history, genetics , mental issues, and the environment can increase someone’s substance abuse susceptibility. That said, let’s look at the factors that contribute to drug addiction based on three categories: social, personal, and risk.
What do admirers find appealing about substance abuse?
Some people find the lifestyle of substance abusers appealing and sometimes even glamorous. Admirers will observe how the community of substance abusers dress, what they do for fun, the music they listen to, their attitude toward responsibility and structure, and find this lifestyle alluring.
Why is victimization more likely to be associated with substance abuse?
Victimization is also positively associated with other forms of substance abuse, including inhalant, hard drug use, and marijuana, that’s why it’s more likely for victims of bullying to engage in substance use than uninvolved youth.
Why do youth turn to substance abuse?
Most youths turn to substance abuse as a way to go against the authorities and the limitations imposed upon them at various institutions and homes.
Why do students have poor academic performance?
Poor academic performance might push students into indulging in substance use. Because they’re usually neglected and lack support from teachers and sometimes even their parents, unlike those teenagers who do well in school.
Is substance abuse a preventable problem?
Even though substance abuse is a chronic problem, it’s both treatable and preventable. At American Addiction Institute of Mind and Medicine, Our goal is to not only assist in providing world-class addiction treatment but to educate you about all aspects of addiction and recovery. Call For Addiction Help.