Treatment FAQ

how soon can breast cancer recur after treatment

by Brandyn Kutch II Published 2 years ago Updated 1 year ago
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This page was reviewed on February 10, 2022. Even after initial treatment is complete and tests show no sign of disease, there is a chance breast cancer may return. When that happens, it's called recurrent breast cancer. In most cases, recurrent cancers appear within the first three years after treatment.

Full Answer

Can breast cancer recur 14 years after treatment?

In other words, an estrogen receptor-positive breast cancer is just as likely to recur 14 years after treatment as three years after treatment. 8 Treatment of a recurrence will depend on whether it is local, regional, or distant.

What is a breast cancer recurrence?

To be considered a recurrence, the malignancy must recur at least a year after successful completion of cancer therapy. As with the original breast cancer, the signs and symptoms of a recurrence can vary. In some cases, the symptoms may be subtle. In others, there may be overt, as is the case with a lump.

How is breast cancer recurrence treated after a mastectomy?

Local recurrence after a mastectomy is usually treated with surgery, and radiation therapy if radiation therapy wasn’t part of the initial treatment. Treatment may also include chemotherapy, hormone therapy and/or HER2-targeted therapy. Metastasis (distant recurrence) is most often found when people report symptoms.

When should I see a doctor about recurrent breast cancer?

Make an appointment with your doctor if you notice any persistent signs and symptoms that worry you. Recurrent breast cancer occurs when cells that were part of your original breast cancer break away from the original tumor and hide nearby in the breast or in another part of your body. Later, these cells begin growing again.

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How soon does breast cancer come back after treatment?

Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence).

Which breast cancer is most likely to recur?

Research suggests that estrogen receptor-positive breast cancer is more likely to come back more than five years after diagnosis. In this study, the researchers looked at the risk of late breast cancer recurrence, meaning the breast cancer came back 10 or more years after diagnosis.

How long can breast cancer recur?

Although most relapses occur during the first 5 years after diagnosis, late recurrence has been reported, especially in luminal breast cancer. Unlike most solid malignancies, breast cancer may recur 5–10 years after initial treatment.

What are the signs of cancer coming back?

Warning signs of a distant recurrence tend to involve a different body part from the original cancer site. For example, if cancer recurs in the lungs, you might experience coughing and difficulty breathing, while a recurrence of cancer in the brain can cause seizures and headaches.

How quickly can cancer come back?

Most cancers that are going to come back will do so in the first 2 years or so after treatment. After 5 years, you are even less likely to get a recurrence. For some types of cancer, after 10 years your doctor might say that you are cured. Some types of cancer can come back many years after they were first diagnosed.

Is breast cancer worse the second time?

After breast cancer was diagnosed a second time, the women's chances of survival were 27% to 47% higher if the second breast cancer was small and had no symptoms when diagnosed, compared to second breast cancers that caused symptoms such as a lump, a skin change, or nipple discharge.

How can you tell if breast cancer has returned?

What are the symptoms of breast cancer recurrence?Breast lump or bumps on or under the chest.Nipple changes, such as flattening or nipple discharge.Swollen skin or skin that pulls near the lumpectomy site.Thickening on or near the surgical scar.Unusually firm breast tissue.

How likely is it for breast cancer to return?

According to the Susan G. Komen® organization, women with early breast cancer most often develop local recurrence within the first five years after treatment. On average, 7 percent to 11 percent of women with early breast cancer experience a local recurrence during this time.

Where does cancer come back after breast cancer?

Cancer beyond the breast area This includes areas near to or around the breast but has not spread to other parts of the body. A locally advanced cancer might come back in one or more of the following: the chest wall. lymph nodes under the breastbone or between the ribs.

Can stress cause breast cancer to return?

They have found no evidence that those who are more stressed are more likely to get cancer. Some people wonder whether stress causes breast cancer. But overall, the evidence for this has been poor. And a large study of over 100,000 women in the UK in 2016 showed no consistent evidence between stress and breast cancer.

What type of cancer is most likely to recur?

Some cancers are difficult to treat and have high rates of recurrence. Glioblastoma, for example, recurs in nearly all patients, despite treatment. The rate of recurrence among patients with ovarian cancer is also high at 85%....Related Articles.Cancer TypeRecurrence RateGlioblastoma2Nearly 100%18 more rows•Nov 30, 2018

Are cancers more aggressive when returning?

Cancer recurrence may seem even more unfair then. Worse, it's often more aggressive in the younger cancer survivor – it may grow and spread faster. This aggressiveness means that it could come back earlier and be harder to treat.

What changes to the breast after mastectomy?

After breast-conserving surgery or a mastectomy, with or without reconstruction, be aware of any changes to either side, such as: swelling on your chest, in your armpit or around your collarbone. a change in shape or size. a change in skin texture, such as puckering or dimpling.

What are the factors that affect the risk of breast cancer recurrence?

Each person’s risk of breast cancer recurrence is different and depends on many factors, such as the size, type, grade and features of the cancer and whether the lymph nodes were affected.

How does a scar feel after breast surgery?

After treatments such as surgery and radiotherapy, you may experience pain and sensations such as burning and numbness in the scar area and under the arm.

What are the symptoms of secondary breast cancer?

severe or ongoing headaches. a dry cough or feeling of breathlessness. feeling much more tired than usual. pain in your bones, for example in the back, hips or ribs, that doesn’t get better with pain relief and may be worse at night. Find out more about the symptoms of secondary breast cancer. Click the image below for a downloadable infographic ...

What to do after discharge from follow up appointment?

After you have been discharged from your follow-up appointments, your GP may be your main contact to get concerns checked quickly. When speaking to your GP, make sure they know about your breast cancer, particularly if you were diagnosed some time ago. If necessary your GP can refer you back to your treatment team.

Can breast cancer recur after treatment?

However, recurrence can happen even many years after treatment, which is why it’s important to be breast and body aware, and report any changes to your treatment team or GP.

Can breast cancer spread to other parts of the body?

Sometimes breast cancer cells can spread from the breast to other parts of the body. This is known as secondary breast cancer. Some symptoms to be aware of include: pain in your bones, for example in the back, hips or ribs, that doesn’t get better with pain relief and may be worse at night.

What is the treatment for breast cancer after lumpectomy?

Radiation therapy may be given if it wasn’t part of the initial breast cancer treatment. Treatment may also include chemotherapy, hormone therapy and/or HER2-targeted therapy.

What tests are needed to check for breast cancer recurrence?

Depending on your signs and symptoms, follow-up tests may include: Blood tests ( including tumor marker tests)

What is a local recurrence?

Local recurrence. When a local recurrence is found, it’s treated in much the same way as the first breast cancer. The tumor is removed by a surgeon, examined by a pathologist and tested for hormone receptor status, HER2 status and other characteristics. Tests are also done to be sure there’s no sign of metastasis.

How to check for breast cancer?

Depending on your signs and symptoms, follow-up tests may include: 1 Blood tests (including tumor marker tests) 2 Imaging tests (such as bone scans, CT scans, PET scans and chest X-rays) 3 A tissue biopsy (to check if a suspicious finding is a recurrence of breast cancer)

When is metastasis found on a mammogram?

Local recurrence is usually found on a mammogram, during a physical exam by a health care provider or when you notice a change in or around the breast or underarm. Metastasis is usually found when symptoms are reported to a provider. If you have a local recurrence or metastasis, it’s not your fault.

Can breast cancer recur after mastectomy?

Local recurrence after mastectomy. Even though the entire breast is removed in a mastectomy, breast cancer can still return to the chest area. If you notice any changes around the mastectomy scar, tell your health care provider. The more lymph nodes with cancer at the time of the mastectomy, the higher the chances of breast cancer recurrence.

Can breast cancer recur?

Most people diagnosed with breast cancer will never have a breast cancer recurrence. However, everyone who has had breast cancer is at risk of recurrence. The risk of breast cancer recurrence varies greatly from person to person. Talk with your health care provider about your risk of recurrence and things you can do that may lower your risk.

What happens after breast cancer treatment?

After your breast cancer treatment ends, your doctor will likely create a schedule of follow-up exams for you. During follow-up exams, your doctor checks for any symptoms or signs of cancer recurrence. You can also report any new signs or symptoms to your doctor.

What is recurrent breast cancer?

Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. Recurrent breast cancer may occur months or years after your initial ...

Why do breast cancer cells grow back?

Recurrent breast cancer occurs when cells that were part of your original breast cancer break away from the original tumor and hide nearby in the breast or in another part of your body. Later, these cells begin growing again.

What are the signs of a breast mastectomy?

A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge. Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall.

How long does hormone therapy last for breast cancer?

Taking hormone therapy after your initial treatment may reduce the risk of recurrence if you have hormone receptor positive breast cancer. Hormone therapy may continue for at least five years.

What are the symptoms of a distant recurrence of cancer?

Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough.

How long can you keep hormones?

Hormone therapy may continue for at least five years. Chemotherapy. For people with breast cancer who have an increased risk of cancer recurrence, chemotherapy has been shown to decrease the chance that cancer will recur, and those who receive chemotherapy live longer. Radiation therapy.

How to tell if breast cancer is recurrence?

Local or regional recurrence will often present with telltale signs, including: Red, swollen, 2  scaling, or puckering breast skin. Streaks of color or an "orange peel" skin texture. A hot area of breast skin. A mass, lump, or thickening of breast tissue. Thickening 2  or inflamed scar tissue.

How long does it take for cancer to recur?

1 . To be considered a recurrence, the malignancy must recur at least a year after the successful completion of cancer therapy.

What is the prognosis of breast cancer?

Prognosis. The likely outcome of a breast cancer recurrence, known as the prognosis, is largely dependent on whether the recurrent is local, regional, or distant. Generally speaking, the more advanced the malignancy is, the greater the impact on survival.

How do you know if you have breast cancer?

In some cases, the symptoms may be subtle. In others, there may be overt, as is the case with a lump. Local or regional recurrence will often present with telltale signs, including: Red, swollen, 2  scaling, or puckering breast skin.

What is stage 4 cancer?

Women with a distant recurrence are treated with systemic therapies (and less commonly, with surgery and radiation) to control the growth of the tumor. Cancers like these are categorized as stage 4, meaning that they cannot be cured. Instead, the focus would be placed on extending life and maintaining the optimal quality of life.

How many women die from triple negative breast cancer?

Some women are successfully treated following the diagnosis and go on to live long, healthy lives. A 2016 study from MD Anderson reported that, among 881 women with triple-negative breast cancer who were disease-free after five years, only 16 deaths occurred in the subsequent five years.

What is the treatment for metastatic breast cancer?

Treatment options for metastatic breast cancer can include chemotherapy, targeted therapies, and immunotherapy (for metastatic triple negative breast cancer). Some drugs are used primarily for people who have BRCA mutations, and others are used for anyone.

How long does it take for breast cancer to come back?

It is these tumors that are more likely (more than 50%) to come back after five years than during the first five years after diagnosis, although some triple-negative tumors pose risk as well.

How long does it take for estrogen receptor positive breast cancer to recur?

The constant rate of recurrence means that the risk that an estrogen receptor-positive breast cancer will recur between 15 years and 16 years post-diagnosis is the same as the risk that it will recur between five years and six years after diagnosis.

What are the risk factors for recurrence?

There are several risk factors that raise the risk of recurrence overall (combining both early and late recurrences). These include: 1 Tumor size: Larger tumors are more likely to recur than smaller ones both early and late. 2 Positive lymph nodes: Tumors that have spread to lymph nodes are more likely to recur at any time than those that have not. 3 Age at diagnosis: Breast cancer recurrence is more common in younger people. 4 Treatments received and response to treatments: Both chemotherapy and hormonal therapy (tamoxifen or aromatase inhibitors) reduce the risk of recurrence in the first five years. 5 Tumor grade: More aggressive tumors (grade 3) are more likely to recur than less aggressive tumors (for example, grade 1), especially in the first five years

What is the fear of recurrence?

Coping with the fear of recurrence can be challenging, especially when the risk of recurrence persists as with estrogen receptor-positive breast cancers. In the past, many people sensed that if they hit the five-year mark, the chances they were home free were high.

How long can you live after breast cancer?

In contrast to the common belief that surviving for five years after cancer treatment is equivalent to a cure, with hormone-sensitive (estrogen and/or progesterone receptor-positive) breast tumors there is a steady rate of recurrence risk for at least 20 years after the original diagnosis, even with very small node-negative tumors.

Why is it important to reduce the risk of breast cancer recurrence?

For people who have estrogen receptor-positive breast cancers (and some triple-negative tumors), reducing the risk of late recurrence is critical in order to reduce deaths from the disease.

How many breast cancers are recurrences?

A recurrence of breast cancer at any time can be devastating. While 6% to 10% of breast tumors are diagnosed when the disease is already metastatic (stage 4), 90% to 94% of metastatic breast cancers represent a distant recurrence of previous early-stage breast cancer (cancer that was originally stage I, stage II, or stage III).

What is the treatment for breast cancer?

If you had breast-conserving surgery (lumpectomy), a local recurrence in the breast is usually treated with mastectomy.

What is the treatment for a recurrence of a tumor near the mastectomy site?

If the initial treatment was mastectomy, recurrence near the mastectomy site is treated by removing the tumor whenever possible . This is often followed by radiation therapy. In either case, hormone therapy, targeted therapy (like trastuzumab), chemotherapy, or some combination of these may be used after surgery and/or radiation therapy.

How to treat breast cancer in the arm?

When breast cancer comes back in nearby lymph nodes (such as those under the arm or around the collar bone), it is treated by removing those lymph nodes, if possible. This may be followed by radiation aimed at the area. Systemic treatment (such as chemo, targeted therapy, or hormone therapy) may be considered after surgery as well.

Is breast cancer hard to treat?

The only difference is that treatment may be affected by previous treatments a woman has had. Recurrent breast cancer can sometimes be hard to treat. If you are in otherwise good health, you might want to think about taking part in a clinical trial testing a newer treatment.

Can breast cancer come back after treatment?

Treatment of Recurrent Breast Cancer. For some women, breast cancer may come back after treatment – sometimes years later. This is called a recurrence. Recurrence can be local (in the same breast or in the surgery scar), regional (in nearby lymph nodes), or in a distant area.

How long does it take to treat estrogen receptor positive breast cancer?

Standard treatment for estrogen receptor-positive, or ER-positive, breast cancer includes five years of the endocrine-based treatments tamoxifen or aromatase inhibitors, both of which are taken daily as a pill. Researchers from the Early Breast Cancer Trialists’ Collaborative Group analyzed data from 88 clinical trials involving 62,923 women ...

How long does breast cancer stay dormant?

Women with small, low-grade cancers and no spread to the lymph nodes had a much lower 10 percent risk of cancer spreading distantly during the next 15 years. “It is remarkable that breast cancer can remain dormant for so long and then spread many years later with this risk remaining the same year after year and still strongly related to the size ...

How long did endocrine therapy last?

The patients all received endocrine therapy for five years and were free of cancer when they stopped therapy. Over the next 15 years, however, a steady number of these women saw their cancer spread throughout the body, as late as 20 years after the initial diagnosis.

What is the risk of recurrence of cancer?

The risk of recurrence was directly tied to the original cancer’s size and characteristics, and to the number of lymph nodes that were cancerous. Among patients who were recurrence-free when they stopped endocrine therapy after five years, the highest risk of recurrence was for those with originally large tumors and cancer ...

Does tamoxifen reduce recurrence?

Doctors have long known that five years of tamoxifen reduces recurrence by about half during treatment and by nearly a third over the next five years. Aromatase inhibitors, which work only in postmenopausal women, are even more effective than tamoxifen at reducing recurrence and death from breast cancer. SEE ALSO: ‘When Are We Going ...

Can estrogen cause breast cancer?

Steady rates of recurrence in women with estrogen receptor-positive disease could influence decisions about long-term therapy. Even 20 years after a diagnosis, women with a type of breast cancer fueled by estrogen still face a substantial risk of cancer returning or spreading, according to a new analysis from an international team ...

What is recurrence of breast cancer?

Breast cancer recurrence can be categorized by where in the body it occurs when it returns. These categories include: Local recurrence – This type of recurrence describes breast cancer that develops in or near the same area where it originally developed, such as scar tissue, the chest wall or other nearby tissue.

What is regional recurrence?

Regional recurrence – Breast cancer that returns in a nearby region, such as the lymph nodes in the armpit or collar bone, is known as a regional re currence. Distant recurrence – Also called metastatic recurrence, this type of recurrence describes breast cancer that returns in a distant area of the body, such as the bones, lungs or liver.

What are the different types of breast cancer?

Breast cancer recurrence can be categorized by where in the body it occurs when it returns. These categories include: 1 Local recurrence – This type of recurrence describes breast cancer that develops in or near the same area where it originally developed, such as scar tissue, the chest wall or other nearby tissue. 2 Regional recurrence – Breast cancer that returns in a nearby region, such as the lymph nodes in the armpit or collar bone, is known as a regional recurrence. 3 Distant recurrence – Also called metastatic recurrence, this type of recurrence describes breast cancer that returns in a distant area of the body, such as the bones, lungs or liver.

How to contact Moffitt for breast cancer?

If you have concerns about your individual risk of breast cancer recurrence that you would like to discuss with a Moffitt physician, call 1-888-663-3488 or fill out a new patient registration form online. We welcome patients with or without a referral.

What is a mastectomy?

Email. A mastectomy is a surgical procedure that removes an entire breast. This procedure may be used as a treatment for breast cancer or a preventative measure for individuals at high risk of developing breast cancer. If your physician has recommended a mastectomy as part of your treatment plan, you may be wondering if this procedure will prevent ...

Can breast cancer recur?

If your physician has recommended a mastectomy as part of your treatment plan, you may be wondering if this procedure will prevent breast cancer recurrence. Although a mastectomy removes all of the breast tissue, there is still a chance that breast cancer can return.

Can breast cancer recur after mastectomy?

Your individual risk for breast cancer recurrence after receiving a mastectomy will depend on several factors, including the type of breast cancer you have and whether it is affected by hormones, the size and location of your tumor, how quickly the cancer cells grew and the stage of cancer at the time of treatment.

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Types

Symptoms

Causes

Late Recurrence

  • Strategies that have been linked to a reduced risk of breast cancer recurrence include: 1. Hormone therapy.Taking hormone therapy after your initial treatment may reduce the risk of recurrence if you have hormone receptor positive breast cancer. Hormone therapy may continue for at least five years. 2. Chemotherapy.For people with breast cancer who ...
See more on mayoclinic.org

Prognosis

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When diagnosed, a recurrence will be categorized as: 1. Local: Occurring in the same place or near the original tumor 2. Regional: Occurring in lymph nodesnear the original cancer 3. Distant: Occurring in distant organs, often the liver, bone, or brain. If cancer grows or spreads during your treatment, this would be defined as …
See more on verywellhealth.com

Coping

  • As with the original breast cancer, the signs and symptoms of a recurrence can vary. In some cases, the symptoms may be subtle. In others, there may be overt, as is the case with a lump. Local or regional recurrence will often present with telltale signs, including:2 1. Red, swollen, scaling, or puckering breast skin 2. Streaks of color or an "orange peel" skin texture 3. A hot area …
See more on verywellhealth.com

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