Treatment FAQ

how long after radioactive iodine treatment could a cat become hyperthyroid again

by Kenyon Maggio Published 2 years ago Updated 2 years ago

It is expected that your cat will return to a euthryoid state (normal) between 2 and 4 months after being treated with 131 Iodine. Hyperthyroidism is caused by hyperactive thyroid glands typically caused by a benign change to one or both thyroid glands where they stop responding to normal feedback mechanisms.

Full Answer

Can a cat still have hyperthyroidism after radioiodine treatment?

A very small proportion of cats (fewer than 1% of the cats we’ve treated to date) are still hyperthyroid 6 months after treatment. For these cats, we would usually plan a second radio-iodine treatment, which will almost certainly be successful.

How long do cats stay in the hospital after iodine 131?

The dose of I-131 used to treat hyperthyroid cats is very small and people and other animals are at very low risk from the radiation. Treated cats are hospitalized until they reach an acceptable low level of radioactivity. However, they will be radioactive to some degree for 82 days following treatment.

What are the risks of radioactive iodine in cats?

Cats treated with radioactive iodine for their hyperthyroidism have several risks unrelated to the radioiodine therapy itself. Risks from hyperthyroidism. The chronic elevation of circulating thyroid hormone levels in cats with hyperthyroidism leads to changes in their heart muscle that predispose them to developing heart failure.

Can a cat be cured of hyperthyroidism with I-131?

Our treatment objectives are to eliminate all hyperactive thyroid tissue and to avoid lifelong methimazole. If these are met, your cat will be healthier. The vast majority of cats will be cured with just one I-131 treatment. Even so, some cats have unusually ‘stubborn’ tissue that may require a second treatment with I-131.

Can hyperthyroidism come back after radioactive iodine in cats?

Most hyperthyroid cats respond fully to a single injection with radio-iodine. Their hyperthyroidism won't come back, and they don't need ongoing medication. Most cats respond to treatment within weeks, although some take up to 6 months to gain the full benefit.

Can cats get hyperthyroidism twice?

Cats that have had surgery may have a recurrence of hyperthyroidism. Blood thyroid hormone levels should be measured once or twice a year. Radioactive iodine is given intravenously and will accumulate in the abnormal thyroid tissue, killing the abnormal thyroid cells but sparing the normal thyroid cells.

How long can a cat live after radioactive iodine treatment?

“Studies have shown that cats treated with I-131 live longer than those treated with pills,” added Mosenco, citing a study where I-131-treated cats lived an average of four to five years following treatment, versus an average of only two years for cats on medication.

What are the long term side effects of radioactive iodine for cats?

There are almost no side effects from radioiodine treatment. When your cat returns home, there may be a readjustment period while your cat's thyroid returns to normal function. Your cat may be quieter and less active . This is due to the metabolic rate returning to normal.

What are the final stages of hyperthyroidism in cats?

Over time, this progresses to increased blood pressure, severe weight loss, heart disease, blindness, and kidney damage. The slow onset of signs means that cat owners will often miss these changes until the late stages of disease.

What is the life expectancy of a cat with hyperthyroidism?

The median survival times reported are 25 (iodine 131 treatment),1 24 (radioiodine treatment),2 and 48 months (iodine 131 treatment),3 with a more recent paper citing 14 months (carbimazole or methimazole treatment alone or in combination with thyroidectomy).

Does radioactive iodine therapy cure hyperthyroidism in cats?

We have treated cats with radioiodine at Cornell for more than 25 years. Radioiodine is safe and effective with cure rates approximately 95 - 98% with one treatment. Cats can receive a second treatment, if necessary.

Should I put my cat down with hyperthyroidism?

When to put a cat to sleep with hyperthyroidism is a heartbreaking decision. If your cat is in pain and has lost a lot of weight or declining health, then it may be time to consider euthanasia. If your cat, however, is still relatively healthy and comfortable, then you may want to wait a little longer.

How do you prevent hyperthyroidism in cats?

Can hyperthyroidism be prevented? There are currently no known preventive measures for hyperthyroidism, but early diagnosis decreases the secondary problems and improves the prognosis. All middle-aged and senior cats should receive a complete physical examination by a veterinarian every six months.

How long can a cat live taking methimazole?

The average life expectancy of a methimazole patient is ~3 years. The average life expectancy of& 131I patients is 4-5+ years with many going as long as 11 years in our experience....Side-effects commonly seen:In the first 3 months: Anorexia, Vomiting & Depression10-20%Paraneoplastic syndrome with poor control>50%8 more rows

What is the best food to feed a cat with hyperthyroidism?

It is best to feed: Canned or raw diets, that contain little to no fruits, vegetables, or grains. Any canned cat food is better than any dry, which contains too much carbohydrate and plant-based protein.

What are the side effects of methimazole in cats?

The most common side effects include vomiting, anorexia, and tiredness, and usually occur within the first three months of treatment. Other, less common side effects such as gastrointestinal effects and mild changes in your pet's blood cell counts are usually temporary and resolve with time.

Why is radioiodine not concentrated in thyroid tissue?

Therefore, the radioiodine is concentrated by the hyperactive, abnormal thyroid tissue. Because the normal thyroid tissue becomes atrophied (decreased in size and ability to function) in the hyperthyroid patient , the normal thyroid tissue itself should not concentrate the radioiodine.

How do you know if your cat has hyperthyroidism?

If left untreated, a hyperthyroid cat can exhibit many, if not all, of the following signs: extreme weight loss, excessive appetite in most cases, but decreased appetite in some, muscle weakness, heart disease (in crease in the size of the heart, increased rate, changes in heart rhythm, cardiac arrest), intolerance to stress, and eventually death.

Why do cats stay in the hospital longer with kidney disease?

Due to the removal of iodine through the kidneys, cats with preexisting kidney disease may have to stay longer because the radioiodine may not be removed from the body as quickly. The patient will be monitored at regular intervals to determine when they are able to be released.

What is the most common hormonal disease in cats?

Hyperthyroidism may be the single most commonly diagnosed hormonal disease in cats next to diabetes. It is generally a disease of older cats with an average age around 9-10+ years, but can be seen in cats as young as 5 years of age. In most cases, the disease is caused by a growth of abnormal, non-cancerous cells which secrete thyroid hormones in ...

How long do you have to keep your dog in the hospital after discharge?

You will need to limit contact with your pet during the two week period following discharge from the hospital. This will include having your pet sleep in an unoccupied room, restricting your pet from food preparation areas, and not letting your pet sit on your lap.

Where to administer radioactive iodine?

The protocol for administering radioactive iodine at the University of Minnesota Veterinary Medical Center is by the subcutaneous route (under the skin). The radioactive iodine is administered as a single injection under the skin in the region of the inner thigh. Because of the nature of the injection, we generally will administer a small amount ...

When can a patient be released from the hospital?

The patient can be released from the hospital once the exposure rate from the radioactivity in the body reaches a level that is deemed to be safe to the general public (i.e.: owners), which has been established by the University and the Minnesota Department of Health.

How long after radio iodine treatment can cats be hyperthyroid?

A very small proportion of cats (fewer than 1% of the cats we’ve treated to date) are still hyperthyroid 6 months after treatment. For these cats, we would usually plan a second radio-iodine treatment, which will almost certainly be successful. This second dose is included within our initial treatment price, although it doesn’t cover lab fees or an in-patient stay longer than 14 days after the second dose.

How long does it take for a cat to see a vet after iodine?

Long-term monitoring. Percy. We suggest that your cat sees its vet at 6 weeks, 3 months and 6 months after radio-iodine treatment, for clinical examinations, blood and urine tests, and blood pressure estimation.

What is the best treatment for hyperthyroidism in cats?

Radio-iodine is the preferred treatment for cats with hyperthyroidism, offering a painless and permanent cure. That means the future for your much-loved pet is much rosier – and longer – than before.

Can cats become hypothyroid?

There’s a risk your cat could become hypothyroid. Some cats are over-sensitive to radio-iodine, and can go the other way – becoming hypo thyroid. This means their thyroid hormone levels have fallen below the normal range, which is the opposite of hyperthyroidism.

How long does it take for a cat to get iodine?

The majority of cats treated with radioactive iodine have normal hormone levels within one to two weeks of treatment. The advantages of radioactive iodine therapy are that the procedure most often cures hyperthyroidism, has no serious side effects, and does not require anesthesia.

How long does radioactive iodine therapy last?

Radioactive iodine therapy is curative within three months of therapy in approximately 95 percent of all hyperthyroid cases. In cases where radioactive iodine therapy is not successful, the treatment can be repeated.

What is the best treatment for hyperthyroidism in cats?

Radioactive Iodine Therapy . When available, radioactive iodine therapy is the treatment of choice for cats with hyperthyroidism. During treatment, radioactive iodine is administered as an injection and is quickly absorbed into the bloodstream.

What causes a cat to vomit?

Vomiting. Diarrhea. Anorexia. Anesthesia. Hyperthyroidism is a common disease in cats, and mostly afflicts cats middle-aged and older. Also called thyrotoxicosis, hyperthyroidism is caused by an increase in production of thyroid hormones (known as T3 and T4) from an enlarged thyroid gland in a cat’s neck. In most cases, enlargement of thyroid ...

What causes a thyroid gland to enlarge?

In most cases, enlargement of thyroid glands is caused by a non-cancerous tumor called an adenoma. Some rare cases of hyperthyroid disease are caused by malignant tumors known as thyroid adenocarcinomas.

How do anti-thyroid drugs work?

Medication. Anti-thyroid drugs act by reducing the production and release of thyroid hormone from the thyroid gland. These medications do not provide a cure for the disease, but they do allow either short-term or long-term control of hyperthyroidism.

How do you know if your cat has hyperthyroidism?

The most common clinical signs of hyperthyroidism are weight loss, increased appetite, and increased thirst and urination. Hyperthyroidism may also cause vomiting, diarrhea, and hyperactivity.

How long does it take for a cat to be treated with radioiodine?

Typically cats treated with radioiodine in our facility spend a total of 3-6 days with us following the radioiodine therapy.

How long does it take for a cat to be discharged from a hospital?

Typically cats treated with radioiodine in our facility spend a total of 3-6 days with us following the radioiodine therapy. The majority of cats are discharged 3 days following their radioiodine therapy. Some cats with larger tumors require larger radioiodine doses and therefore require longer hospitalization periods prior to release.

What is the leading cause of death in cats?

Administering Subcutaneous Fluids. Hyperthyroidism is a disease of geriatric cats. Chronic kidney disease is common in geriatric cats and is currently the single leading cause of death in cats as a whole. A significant percentage of cats with hyperthyroidism (roughly 30%) have concurrent chronic kidney disease.

What is the hardest part of giving subcutaneous fluids to cats?

Furthermore, while the process of inserting the needle initially seems like the most difficult part of the process, the hardest part about giving subcutaneous fluids is actually preventing the cat from trying to leave the area during the administration process.

Is the rate at which fluids enter the subcutaneous space of the cat directly proportional to the height differential between

Also keep in mind that the rate at which the fluids enter the subcutaneous space of the cat are directly proportional to the height differential between the bag and the cat. The relative height of the fluids bag hanging above the cat in a closet further contributes to a timely completion of the task.

What is the I-131 in cats?

General Information about Feline Hyperthyroidism and I-131 Therapy in Cats. Cat hyperthyroidism is a commonly diagnosed endocrine pathology in older cats. It is caused by a tumor that produces too much feline thyroid hormone. The disease is usually fatal if left untreated. Feline Hyperthyroidism may be treated with medicine, surgery, ...

Does thyro cat damage other tissue?

Does not damage other tissue or organs, including the parathyroid glands. Does not have harmful side effects. Returns thyroid function to normal usually within one month. Is cost effective. Thyro-Cat is an approved specialty facility with State Department of Health and Nuclear Regulatory Commission for use of I-131.

Can Iodine be used for hyperthyroidism in cats?

Surgery may not be effective in removing all of the affected thyroid tissue causing feline hyperthyroidism. Radioactive Iodine (I-131) therapy for feline hyperthyroidism is very effective, has few side effects, is a one-time treatment in over 95% of cats with hyperthyroidism, and does not require administration of pills or anesthesia.

Can cats take tapazole?

The disease is usually fatal if left untreated. Medical therapy for feline hyperthyroidism (methimazole - Tapazole®) is required daily, is a life-long treatment, and does not cure the cat's hyperthyroid condition. The difficulties associated with giving pills to cats often causes stress to both the animal and owner.

Can Iodine 131 be used on cats?

The I-131 hyperthyroid cat treatment is absorbed quickly into the cat's bloodstream and the diseased thyroid tissue. Once in the thyroid, it destroys the overactive portions of the thyroid gland. Radioactive Iodine I-131 feline hyperthyroidism treatment has the following advantages over medical and surgical treatments for feline hyperthyroidism:

Is I-131 safe for cats?

It is as easy as one injection just under the skin, much like a routine feline vaccine. I-131 is safe and effective.

Is radioactive iodine therapy expensive?

The cost of radioactive iodine therapy is similar to the other forms of therapy, and is often less expensive when compared to long term medical therapy or the higher probability of a required second surgery. Prior to making a final decision relative to initiating the I-131 hyperthyroidism therapy, all cats are screened closely for the presence ...

How effective is radioiodine for cats?

We have treated cats with radioiodine at Cornell for more than 25 years. Radioiodine is safe and effective with cure rates approximately 95 - 98% with one treatment. Cats can receive a second treatment, if necessary. Radioiodine treatment avoids surgery , anesthesia, and anti-thyroid drugs.

Where is iodine taken from cats?

The iodine is taken into the thyroid gland and incorporated into thyroxine. The majority of cats have normal hormone levels within a week or two of treatment. Hospitalization is required under the radioisotope permit issued by New York State to Cornell.

How to keep cat from getting contaminated?

Use disposable plastic gloves and litter box liners to help prevent contamination. Wash with soap and water after cleaning the litter box. All used disposable gloves should be stored with the waste—treat them as if they are contaminated. ---Please keep your cat indoors if the cat uses garden areas as a litter box.

How long after a cat is discharged from the hospital can you isolate them?

Cats treated with radioiodine (I-131) have a low level of radioactivity following discharge from the hospital. This level is sufficiently low that complete isolation of the cat from people is not required. Follow these guidelines for 3 weeks after your cat comes home to eliminate or further reduce human exposure to radiation that is emitted by the cat and by radioiodine that is excreted by the cat in urine and saliva.

How do anti-thyroid drugs work?

Anti-thyroid drugs inhibit the production of thyroxine by blocking reactions that produce the hormone. These drugs are usually effective but may be needed lifelong. As with any drug, there can be adverse reactions. These include loss of appetite, vomiting, depression, bleeding, liver problems, facial swelling and itching. Pills are given two times a day. Periodic exams are needed to check hormone levels and adjust the dosage. Long term therapy (years) is discouraged because the thyroid tumor continues to grow and eventually drugs may not work.

What is the procedure to remove the thyroid gland in cats?

Surgical Treatment: Removal of the thyroid gland is a surgical procedure with a good success rate. General anesthesia is used with attendant risk and older cats may have heart, kidney or other problems that cause complications. Loss of the parathyroid gland can cause problems with calcium metabolism.

How long after a cat comes home can you let it sleep?

Follow these guidelines for 3 weeks after your cat comes home to eliminate or further reduce human exposure to radiation that is emitted by the cat and by radioiodine that is excreted by the cat in urine and saliva. ---Do not allow your cat to sit on or sleep with anyone after coming home.

Causes

Pathophysiology

Symptoms

  • Clinical Signs Cats afflicted with hyperthyroidism usually develop a variety of signs that may be subtle at first but that become more severe as the disease progresses. The most common clinical signs of hyperthyroidism are weight loss, increased appetite, and increased thirst and urination. Hyperthyroidism may also cause vomiting, diarrhea, and hyperactivity. The coat of affected cats …
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Diagnosis

  • Diagnosis A veterinarian who suspects a cat has a thyroid problem will conduct a physical examination and palpate the cats neck area to check for an enlarged thyroid gland (see Figure 2). The cats heart rate and blood pressure may also be checked. If thyroid disease is a possibility, your veterinarian will likely order a blood chemistry panel and an analysis of thyroid hormone lev…
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Treatment

  • Treatment There are four treatment options for feline hyperthyroidism: medication, radioactive iodine therapy, surgery, and dietary therapy. Each treatment option has its advantages and disadvantages. The treatment a cat receives for hyperthyroidism will depend on specific circumstances, including the patients overall health status, the owners ability and willingness to …
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Results

  • Radioactive iodine therapy is curative within three months of therapy in approximately 95 percent of all hyperthyroid cases. In cases where radioactive iodine therapy is not successful, the treatment can be repeated. Rarely, a permanent reduction in thyroid-hormone levels called hypothyroidism occurs after radioactive iodine treatment. If this is a...
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Benefits

  • Removal of the thyroid glands, called surgical thyroidectomy, is a relatively straightforward surgical procedure that has a good success rate. The advantage of surgery is that it is likely to produce a long-term or permanent cure in most cats, and therefore eliminates the need for long-term medication.
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Clinical significance

  • Because of the important role the thyroid gland plays in the body, some cats with hyperthyroidism develop secondary problems, including heart disease and high blood pressure. Elevated thyroid hormones stimulate an increased heart rate and a stronger contraction of the heart muscle, and can cause thickening of the left ventricle of the heart over time. If left untreated and unmanaged…
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Prognosis

  • Hypertension, or high blood pressure, is another potential complication of hyperthyroidism, and can cause additional damage to several organs, including the eyes, kidneys, heart, and brain. If hypertension is diagnosed along with hyperthyroidism, drugs may be needed to control the blood pressure and reduce the risk of damaging other organs. As in the case of heart disease, after th…
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