What is NanoKnife?
Nanoknife is a treatment method in prostate cancer. Used for prostate cancer treatment and varies according to the degree of cancer Prostate cancer is the most common tumor in men in the United States of America and the second most common after lung cancer in our country and can result in death if left untreated.
What kind of cancer can NanoKnife treat?
Breast Cancer. Bowel Cancer / Colorectal Cancer. The NanoKnife cancer treatment system is a new technology that gives a treatment option to those patients with the most difficult to treat cancers who are not suitable for conventional therapies. NanoKnife has the potential to prolong survival and provide a good quality of life.
What is NanoKnife ablation?
The new NanoKnife technology uses electrical pulses to destroy cancer cells (electroporation) but leaves surrounding tissue unaffected. How is NanoKnife ablation performed? A patient undergoing treatment with NanoKnife is admitted to hospital on the morning of the procedure. A series of blood tests and cardiac tracing tests will be performed.
How long does nanoknife treatment take?
NanoKnife probes are then placed around the tumor, delivering a series of electrical impulses until it is destroyed. NanoKnife patients can expect a five to seven-day hospital stay, depending on the extent of their surgery.
What is the NanoKnife procedure?
An ablation procedure that uses low energy electrical pulses to create defects (pores) in cell membranes, resulting in loss of homeostasis and subsequent cell death.
Can NanoKnife cure cancer?
NanoKnife uses needles which are guided into position around the tumour using ultrasound or CT scans. Once the needles are in the correct position, a strong electric current is passed between them, killing the cancer cells in the tumour without the need for cuts or incisions.
How is the NanoKnife procedure helpful?
The NanoKnife's precision enables surgeons to perform treatment on the cancerous part of the prostate without treating the whole gland in order to minimise side-effects. NanoKnife technology compares favourably to other ablation technologies because it does not use heat to destroy tumour cells.
Can NanoKnife cure pancreatic cancer?
NanoKnife Offers Promising Treatment Option for Locally Unresectable Pancreas Tumors. Patients with localized (stages I and II) pancreatic adenocarcinoma are typically offered surgical removal to give the best chance for long-term survival.
Who uses NanoKnife?
The NanoKnife System is a next-generation ablative technology that physicians have identified as an innovative treatment for pancreatic cancer, as evidenced by 42 publications documenting more than 800 patients that have been treated for Stage III pancreatic cancer with NanoKnife technology between 2012 to 2019.
Is CyberKnife the same as NanoKnife?
Nanoknife is different from CyberKnife and traditional surgery because it can be completed much more quickly and with far less recovery time. Recovery from a NanoKnife procedure includes no significant medical restrictions and patients may resume normal activities, as they feel ready to do so.
Does insurance cover NanoKnife?
As with focused ultrasound, most insurers do not specifically cover NanoKnife treatment.
Does Medicare cover NanoKnife?
Documents that payors can request include the surgical/operative note, letter of medical necessity, and for pancreatic and prostate cancers, the NanoKnife designation as a breakthrough device, and national Medicare coverage under the DIRECT and PRESERVE clinical trials7.
Is NanoKnife a nanotechnology?
“Nanotechnology” refers to the technology involved in working on a microscopic level – as small as individual molecules and atoms. So the “NanoKnife” isn't actually a knife -- but an electric field – that can be precisely targeted to “poke” tiny holes in tumor cells, while not affecting adjacent organs.
What is the most effective treatment for pancreatic cancer?
Gemcitabine has been the most widely used chemotherapy drug for treating metastatic pancreas cancer. Other drug combinations include gemcitabine with erlotinib (Tarceva), gemcitabine with capecitabine, gemcitabine with cisplatin, and gemcitabine with nab-paclitaxel.
Can Stage 4 pancreatic cancer go in remission?
Stage IVB pancreatic cancer is also called metastatic. The goal of treatment for patients with localized IVA disease is to induce a remission, or a disease-free period that may last months or years. Management of patients with Stage IVB disease is often aimed at controlling symptoms and pain from the cancer.
What are the latest treatments for pancreatic cancer?
The researchers found that in 34 patients with advanced pancreatic cancer randomized to receive the immunotherapy nivolumab with two chemotherapy drugs, nab-paclitaxel and gemcitabine, had a one-year survival rate of 57.7 percent, significantly greater than the historical average of 35 percent with chemotherapy alone.
What is nanoknife treatment?
The NanoKnife cancer treatment system is a new technology that gives a treatment option to those patients with the most difficult to treat cancers who are not suitable for conventional therapies. NanoKnife has the potential to prolong survival and provide a good quality of life. Professor Edward Leen pioneered this treatment in the UK and he outlines here how it works.
Is nanoknife safe?
radiofrequency ablation/microwave ablation) that have been used over the last twenty years to treat inoperable cancer. This treatment is still very new but there have been no deaths attributed to the NanoKnife and the adverse events have been very minor.
What is NanoKnife Surgery?
NanoKnife or irreversible electroporation (IRE) is a treatment pathway to remove cancerous tissue, approved by the FDA. Developed for over a decade, IRE is an advanced system that preserves healthy tissue with minimal impact on the body. This treatment can be accessed through the OncoloMed network of hospitals and specialist oncologists.
What Types of Cancer is NanoKnife More Commonly Used to Treat?
NanoKnife is an ablation (surgical removal) procedure that may be a viable option for patients with inoperable tumours or those that are difficult to access. Some patients may have already had a range of therapies to treat their tumours before their doctors consider IRE a relevant option.
How is NanoKnife Surgery Performed?
This treatment is performed under general anaesthetic for patient comfort and takes a relatively short amount of time in comparison to more traditional surgical options.
Potential Side Effects of NanoKnife
Irreversible electroporation or IRE is usually a minimally invasive and rapid procedure which does not significantly impact on the body.
Preparing for NanoKnife Surgery
Before treatment takes place, your care team will discuss the procedure with you, so that you are fully prepared. Every patient is different, so an individual plan is important. It is a good idea to ask any questions you may have during these discussions, so that you are confident of your treatment.
Post-treatment Care
In comparison to many other cancer treatment options, NanoKnife ablation surgery has a relatively short recovery and discharge time.
Coping After the Treatment & Pain Management
You will be invited for follow-up appointments to ensure that the treatment has been successful. These may include the following:
What is nanoknife surgery?
Carol G. Simon Cancer Center at Morristown Medical Center was the first in New Jersey to offer NanoKnife surgical ablation, also known as irreversible electroporation (IRE), and our medical professionals were trained by the pioneer of the technology. We use it for the treatment of: 1 Unresectable pancreatic tumors that are confined to the pancreas 2 Liver tumors that involve the hepatic arteries, veins or portal vein 3 Colorectal liver metastases 4 Neuroendocrine tumors
Why is nanoknife used for tumors?
The NanoKnife® System provides a solution to this problem, using electrical currents instead of heat, so it causes no harm to blood vessels, veins and bile ducts. This allows surgeons to treat tumors in difficult locations that previously would have been inoperable.
Nanoknife (Nanoblade)
Prostate cancer is the most common tumor in men in the United States of America and the second most common after lung cancer in our country and can result in death if left untreated.
What is Electroporation?
If an electric field is created by applying low-energy direct current (LEDC) between two electric surfaces to cells with cell membrane permeability, the phenomenon of temporary or permanent permeability in the cell membranes is called electroporation. It happens in two ways
How is Nanoknife Used in Prostate Cancer Treatment?
The pathology result of the patient whose perineal fusion biopsy is performed from the suspicious area as a result of multiparametric MRI is expected. If prostate cancer is diagnosed as a result of pathology, the disease is staged. The treatment plan is determined according to the staging, grade and age of the patient.
What are the Advantages of Nanoknife Treatment?
The most important and frightening complication of the surgical treatment of prostate cancer is urinary incontinence and erectile dysfunction. This situation may also occur with other local treatments. Nanoknife treatment, on the other hand, does not cause these complications because no burning-freezing procedure is performed.
What is the Success Rate of Nanoknife Treatment?
In studies conducted, no cancer cells were found in prostate fusion biopsies performed one year later in 80-90% of the patients treated with nanoknife. In the remaining 10-20% of patients, cancer cells were found in biopsies, and most of them were re-treated with the Nanoknife method and eventually no cancer cells were found.
What is nanoknife?
What It Is. NanoKnife is a device that uses a process called irreversible electroporation to cause cells to die. During electroporation, a technique originally used in the lab to see how genes work in cells, an electric field is applied to cells and penetrates and opens up holes in cell membranes, causing cellular damage without damaging ...
Why is nanoknife so effective?
Why This Treatment is So Effective. NanoKnife is a way of destroying tumors that may be in close proximity to important structures. For example, NanoKnife can be an effective technique for treating areas close to blood vessels that you may not want to treat with radiation therapy.
Why is nanoknife not being used universally?
NanoKnife isn’t yet being used universally because bigger research studies need to be done to learn more about the various applications and overall effectiveness of this procedure.
How long does nanoknife last?
In the study, patients had a median overall survival of 24 months, double the survival rate of chemotherapy and chemoradiotherapy.
How does nanoknife work?
NanoKnife involves the placement of long, thin needles under image guidance to deliver targeted therapy, sending electrical pulses directly into the tumor that cause cancer cells to die while preserving important structures such as ducts, veins and nerves around the treatment site.
Is nanoknife still available?
Another study of patients with advanced pancreatic cancer also showed increased survivorship. NanoKnife still is a relatively new treatment. It was pioneered at the University of Louisville and treatment centers including Johns Hopkins and the University of Miami also have made this procedure available to patients.
Is nanoknife safe for soft tissue?
NanoKnife is approved for treatment of tumors in any soft tissue. People with tumors that cannot be removed surgically or treated with radiation may be candidates. Patients with tumors that have been treated with radiation or surgery may also be candidates for the procedure in order to provide additional treatment.
Treatment Costs In Germany
The treatment of prostate cancer varies from patient to patient, thus it is impossible to say which costs will occur. It is possible that only a small tumor has to be removed from the prostate and no further measures are necessary afterwards. In this case, the expenses remain comparably low.
How Is Electroporation Treatment Performed
This type of treatment is carried out under a general anaesthetic and takes around 45 minutes. The procedure is performed as a day case.
New Research And Perspectives
Our experts work closely with leading research institutes of Oncology, allowing to immediately put into practice innovative methods of cancer treatment.
Prostate Cancer Treatment Cost In Poland
Prostate cancer is one of the most common cancer in Poland. The survival rate in Prostate cancer in Poland was low a decade back, however, with the invitation of new technology both for the diagnosis and treatment, the prostate cancer is kept under control resulting in improved survival rate.
What Are The Nanoknifes Benefits
The NanoKnifes precision enables surgeons to perform treatment on the cancerous part of the prostate without treating the whole gland in order to minimise side-effects.
Qualification For The Prostate Cancer Nanoknife Ire Treatment Procedure
Qualification criteria for NanoKnife prostate cancer low-invasive surgery:
Who Are Suitable Candidates For Nanoknife Therapy
NanoKnife Therapy is not suitable for all types of prostate cancer. Men suitable for Nanoknife treatment are carefully selected following MRI and prostate mapping biopsies.
