What is the difference between first line and second line therapy?
May 05, 2017 · I replace the hole caps with the solid caps because I feel like it's safer for the patients. Also, make sure that you keep the cap end sterile. You don't want to introduce any kind of bacteria into the pressure line. 3. Press the "zero" button on your monitor. Wait for it to zero the line. On our monitors it takes about five seconds or so. 4.
What is second-line treatment?
Therefore, long-acting stimulants are the first-line treatment for adult ADHD patients. Titration of doses. If short-acting methylphenidate or dextroamphetamine is used, the starting dose is 10 mg for methylphenidate or 5 mg for dextroamphetamine (see Table 2). This dose should be titrated upward for 10 mg or 5 mg every 7 days until the optimal ...
What is the purpose of zeroing a pressure line?
Treating stage 0 melanoma. Stage 0 melanoma (melanoma in situ) has not grown deeper than the top layer of the skin (the epidermis). It is usually treated by surgery (wide excision) to remove the melanoma and a small margin of normal skin around it. The removed sample is then sent to a lab to be looked at with a microscope.
What is a zero-parting-line process?
What is the difference between first line and second-line treatment?
Second-line treatment is treatment for a disease or condition after the initial treatment (first-line treatment) has failed, stopped working, or has side effects that aren't tolerated.Jun 9, 2020
What is the second-line treatment for SCLC?
Lurbinectedin was active as second-line therapy for SCLC in terms of overall response and had an acceptable and manageable safety profile.Mar 27, 2020
Is the first line treatment?
First-line treatment or therapy simply refers to the initial, or first treatment recommended for a disease or illness. This may also be referred to as primary treatment, initial treatment, or induction therapy. With many conditions, including cancer, there are many possible treatments that could be effective.Mar 30, 2021
What are treatment lines?
“Lines of therapy” is the term used to describe the order in which different therapies are given to people as their disease progresses.May 5, 2021
What does third line treatment mean?
Treatment that is given when both initial treatment (first-line therapy) and subsequent treatment (second-line therapy) don't work, or stop working.
What is carboplatin made of?
Chemistry. In terms of its structure, carboplatin differs from cisplatin in that it has a bidentate dicarboxylate (the ligand is CycloButane DiCarboxylic Acid, CBDCA) in place of the two chloride ligands, which are the leaving groups in cisplatin.
What does 1l mean in oncology?
The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation. When used by itself, first-line therapy is the one accepted as the best treatment.
What are the 5 types of diuretics?
Understanding the 5 Classes of DiureticsLoop Diuretics. Loop diuretics have their effects in the ascending limb of the loop of Henle. ... Thiazides and Thiazide-Like Diuretics. ... Carbonic Anhydrase Inhibitors. ... Potassium-Sparing Diuretics. ... Osmotic Diuretics. ... Nursing Considerations.Oct 4, 2021
Which is better amlodipine or telmisartan?
Treatment with telmisartan/hydrochlorothiazide resulted in the quicker onset of blood pressure-lowering effects compared with telmisartan/amlodipine. The target therapeutic blood pressure was similar in both groups at the 12-week visit.
What is 2nd line therapy?
Treatment that is given when initial treatment (first-line therapy) doesn't work, or stops working.
How effective is second-line chemotherapy?
In three phase III randomised trials of 5-FU-based first-line therapy enrolling a total of 1080 patients, 20% of them went on to receive second-line chemotherapy, with a response rate observed as 13.3% (95% CI, 6.8–22.5%), and a median survival from starting second-line therapy of 5.6 months (Chau et al, 2004a).
What is a second-line antibiotic?
Antibiotics were classified as “first-line” (amoxicillin, TMP-SMX, or erythromycin) or “second-line” (clarithromycin, azithromycin, amoxicillin-clavulanate, cephalosporin, or fluoroquinolone).
Why Do You Zero An Arterial or CVP Line?
Zeroing any kind of line that is monitoring pressure helps to give you the most accurate reading possible. You are closing off the line to the patient (so that no air goes inside of them while zeroing) and then opening the line up to air.
Steps for Zeroing
You can zero a pressure line in five easy steps. We're going to refer to the following picture to help us with learning how to zero a pressure line:
What are the symptoms of ADHD?
ADHD is characterized by behavioral and cognitive symptoms such as hyperactivity, inattention, disorganization, and impulsivity. The symptoms must be severe and cause clinically significant impairment persistently in multiple domains of an individual’s life in order to warrant a diagnosis.
How many people with ADHD have depression?
Retrospective studies of adults with ADHD have demonstrated that 30%–50% have had one or more episodes of depression, while 40%–60% have had an anxiety disorder throughout their lifespan ( Sobanski 2006 ).
Is ADHD a childhood disorder?
ADHD was considered for many years to be a disorder limited to childhood due to diminishing externalizing behaviors. However, as longitudinal studies have demonstrated, the symptoms remain clinically significant for the majority of ADHD patients well into adulthood ( Weiss and Hechtman 1993 ).
What is the treatment for ADHD?
Treatment of adults with ADHD consists of medication and psychosocial treatment. Each treatment modality addresses particular problems of ADHD patients. The treatments can be administered separately or as is most common, both types of treatments can be combined.
Can stimulants cause seizures?
In rare cases stimulants may cause seizures, hypertension, psychosis, hepatotoxicity, and in children stimulant may effect growth ( Power 2000; Greenhill 2001 ). Many side effects emerge early in the course of therapy with stimulants and decline in intensity over time.
Is paroxetine a monotherapy?
In a study of the treatment of adults with ADHD and comorbid anxiety and depressive disorders, Hechtman and colleagues compared the efficacy of paroxetine as a monotherapy, dextroamphetamine as a monotherapy and the combination of both medications.
What is stage 0 melanoma?
It is usually treated by surgery (wide excision) to remove the melanoma and a small margin of normal skin around it. The removed sample is then sent to a lab to be looked at with a microscope.
Where does melanoma come back?
Almost any organ can be affected. Most often, the melanoma will come back in the lungs, bones, liver, or brain. Treatment for these recurrences is generally the same as for stage IV melanoma (see above).
Does melanoma spread to lymph nodes?
The width of the margin depends on the thickness and location of the melanoma. Because the melanoma may have spread to nearby lymph nodes , many doctors recommend a sentinel lymph node biopsy (SLNB) as well. This is an option that you and your doctor should discuss.
What is the best treatment for melanoma?
Radiation therapy to the brain (ster eotactic radiosurgery or whole brain radiation therapy) may help as well. Systemic treatments ( immunotherapy, targeted therapy, or chemo) might also be tried. As with other stages of melanoma, people with recurrent melanoma may want to think about taking part in a clinical trial.
Does melanoma come back after treatment?
Treatment of melanoma that comes back after initial treatment depends on the stage of the original melanoma, what treatments a person has already had, where the melanoma comes back, and other factors.
Can melanoma come back after surgery?
Melanoma might come back in the skin near the site of the original tumor, sometimes even in the scar from the surgery. In general, these local (skin) recurrences are treated with surgery similar to what would be recommended for a primary melanoma. This might include a sentinel lymph node biopsy (SLNB). Depending on the results of the SLNB, other treatments might be recommended as well.
Can lymph nodes be dissectioned?
If the SLNB finds that the sentinel node contains cancer cells, then a lymph node dissection (where all the lymph nodes in that area are surgically removed) will probably be done at a later date. Another option might be to watch the lymph nodes closely by getting an ultrasound of the nodes every few months.
Lines of Treatment
The Option of Clinical Trials
Questions to Ask About Second-Line Treatments
Example
Coping
