Why do tumors have the most number of dividing cells?
Because tumors grow rapidly and therefore have the most number of dividing cells. How is the dosage of chemotherapy (anti-neoplastic) drugs calculated? According to body weight, or body surface area (BSA) and vital organ function (kidney).
What is involved in the treatment of cancer?
Involves the use of x-rays or gamma rays to damage cancer cells. Damage dividing cells; stimulate apoptosis (death); halt cell cycle. What is surgery r/t cancer? Removes the tumor from the body. Reduce tumor size to alleviate pain; prevent metastasis if used early, diagnosis of cancer What are the adverse effects (a/e) of surgery? Pain, deformity
How do cancer cells grow and divide?
Cancer cells originate within tissues and, as they grow and divide, they diverge ever further from normalcy. Over time, these cells become increasingly resistant to the controls that maintain normal tissue — and as a result, they divide more rapidly than their progenitors and become less dependent on signals from other cells.
How do cancer-related mutations affect cell division?
Other cancer-related mutations inactivate the genes that suppress cell proliferation or those that signal the need for apoptosis. These genes, known as tumor suppressor genes, normally function like brakes on proliferation, and both copies within a cell must be mutated in order for uncontrolled division to occur.
Why does chemotherapy affect rapidly dividing cells?
Because cancer cells divide much more often than most normal cells, chemotherapy is much more likely to kill them. Some drugs kill dividing cells by damaging the part of the cell's control centre that makes it divide. Other drugs interrupt the chemical processes involved in cell division.
What are the three rapidly dividing cells affected by chemotherapy?
Cancer cells typically grow and divide more rapidly than normal cells. The fast-growing normal cells most likely to be affected by chemotherapy are blood cells forming in the bone marrow, and cells in the digestive tract, reproductive system, and hair follicles.
How do cancer treatments affect cell division?
The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Usually, cancer drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cancer cells are unable to divide, they die.
Which type of cancer treatment involves the use of medications to alter cell growth and division?
Chemotherapy drugs target cells at different phases of the cell cycle.
How might targeting rapidly growing cells explain common chemotherapy side effects such as hair loss and nausea?
Hair loss is a common side effect of chemotherapy treatment. This is because chemotherapy targets rapidly-dividing cells throughout the body, aiming at the cancer but also affecting the healthy cells that produce hair on the scalp and all over the body.
What is the process of chemotherapy?
Doctors typically administer chemotherapy in cycles, with rest periods between 1–4 weeks. Cycles have rest periods in between to allow a person's body to recover. An individual might have treatment on one day, followed by 1 week's rest, then another 1-day treatment followed by a 3-week rest period, and so on.
How does radiation help treat cancer?
At high doses, radiation therapy kills cancer cells or slows their growth by damaging their DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or die. When the damaged cells die, they are broken down and removed by the body. Radiation therapy does not kill cancer cells right away.
What are the 3 ways cancer can spread?
There are three primary ways tumors can spread to distant organs: Through the circulatory (blood) system (hematogenous) Through the lymphatic system. Through the body wall into the abdominal and chest cavities (transcoelomic).
What are three circumstances where mitosis or cell division will occur?
The three circumstances where cell division or mitosis will occur is in growth development, regeneration and replacement.
What factors determine the treatment plan an oncologist chooses for a particular patient?
The seven factors were their age at the time of decision, having a partner, having children, inability to work due to side-effects of the treatment, the nature of the side-effects, disease-related life expectancy and baseline QOL.
Which of the following characteristics would be most important for a chemotherapeutic drug?
Which of the following characteristics would be most important for a chemotherapeutic drug designed to treat cancer cells? It specifically inhibits the cell division cycle in rapidly dividing cells.
Which component of cell division machinery is frequently targeted by anti cancer drugs?
The protein strands that reach from one end of the cell to the other are called microtubules. These proteins are assembled and disassembled during the cell division process. They are the target of several different chemotherapy agents.