Treatment FAQ

which agents are used in the treatment of tmd

by Ms. Sally Russel MD Published 2 years ago Updated 2 years ago
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This article reviews the pharmacology, toxicology, and research supporting the use of a host of pharmacologic agents that have been used in patients who have TMD, including nonsteroidal anti-inflammatory drugs, corticosteroids, benzodiazepines, nonbenzodiazepine sedative hypnotics, opioids, skeletal muscle relaxants, capsaicin, transdermal lidocaine, antidepressants, and anticonvulsants.

The most effective pharmacological agents used to treat TMD include nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, corticosteroids, anxiolytics, muscle relaxants, antidepressants, and anticonvulsants (Ouanounou et al., 2017).Jan 29, 2021

Full Answer

What medications are used to treat TMD?

Temporomandibular joint disorders (TMD) are a common health condition caused by the structural or functional disorders of masticatory muscles and the temporomandibular joint (TMJ). ... and other discomfort, which could be … Therapeutic Agents for the Treatment of Temporomandibular Joint Disorders: Progress and Perspective Front Pharmacol ...

Are there FDA-approved devices for TMD?

This article reviews the pharmacology, toxicology, and research supporting the use of a host of pharmacologic agents that have been used in patients who have TMD, including nonsteroidal anti-inflammatory drugs, corticosteroids, benzodiazepines, nonbenzodiazepine sedative hypnotics, opioids, skeletal muscle relaxants, capsaicin, transdermal lidocaine, …

What is the management protocol for TMD?

TMD is a complex medical condition which can be difficult to treat. Non-surgical treatment options include: Behavioral changes (for example, avoiding gum …

How is temporomandibular dysfunction (TMD) treated?

Mar 21, 2022 · Condylotomy is a surgical procedure that has been used as an option to treat temporomandibular disorder (TMD) patients. This technique has the advantage of avoiding intra-capsular alterations that might be found involving other surgical procedures. Its use, even when unilateral, has positive effect on treatment of both joints. Methods

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What are the treatment options for TMD?

Treatment Options for TMD/TMJ:
  • Medications. ...
  • A splint or night guard. ...
  • Dental work. ...
  • Transcutaneous electrical nerve stimulation (TENS). ...
  • Ultrasound. ...
  • Trigger-point injections. ...
  • Radio wave therapy. ...
  • Low-level laser therapy.

What is the most common treatment for TMJ?

2) Bite Correction

Bite guards are the most widely recommended treatment for moderate TMJ symptoms. Research has found that splints can reduce TMJ pain and the risk of long-term side effects is minimal. There are two main types of dental splint, a TMJ mouthguard, and a bruxism (tooth grinding) mouthguard.
Jan 6, 2021

Which pharmacotherapy can be best used to treat temporomandibular disorder?

Gabapentin and pregabalin have been used for the treatment of TMD. Both are synthetic compounds structurally related to GABA, the primary inhibitory neurotransmitter in the CNS.Aug 8, 2017

What is the best muscle relaxer for TMJ?

One of the best examples of muscle relaxant that is used in TMD treatment is diazepam. Tricyclic anti-depressants: These medicines can help you to get relief from the pain caused by TMD.May 8, 2020

Who can diagnose TMD?

TMJ disorder causes pain in the muscles that control jaw movement. This is also known as temporomandibular disorder (TMD). This condition will require a diagnosis from your St. Louis doctor or dentist.Sep 15, 2021

Is TMJ a synovial joint?

We conducted a genetic analysis of the developing temporo-mandibular or temporomandi-bular joint (TMJ), a highly specialized synovial joint that permits movement and function of the mammalian jaw.

Is Mobic good for TMJ?

Mobic. Mobic (meloxicam) is an NSAID (non-steroid anti-inflammatory drug) that is used to inhibit hormones that cause inflammation. Often prescribed for arthritis, Mobic can treat inflammation associated with TMJ. In fact, some forms of TMJ are related to arthritis located in the mandibular joint.Oct 5, 2020

Can antibiotics help TMJ?

The inflammation of the TMJ observed in the present patient was clearly related to bacterial infection: this is why the patient's symptoms, such as difficulty opening the mouth, swelling, and pain in the left TMJ and mandible, promptly resolved after oral and intravenous administration of cephem antibiotics.

Do NSAIDs help TMJ?

Non-steroidal anti-inflammatory drugs (NSAIDs) help temporarily control both jaw pain and inflammation in the TMJ. An example of an NSAID is ibuprofen (eg, Advil). Muscle relaxants are sometimes used to help relieve jaw pain and discomfort due to a TMJ disorder.

What vitamin is good for TMJ?

Magnesium. Magnesium deficiency can lead to tense, spastic muscles. It also contributes to bone strength, nerve function, and cartilage health. In combination with calcium, these two supplements can work together to help relax your jaw muscles and relieve your TMJs of excess strain and tension.Oct 2, 2019

Is diclofenac good for TMJ?

Our results demonstrate that topically applied diclofenac and oral diclofenac are equally effective in the treatment of temporomandibular joint dysfunction symptoms.

Is Celebrex good for TMJ?

Celecoxib showed slightly better pain reduction than placebo, but was not significantly effective for temporomandibular disorder pain. Celecoxib and naproxen were well tolerated, with similar number of reported adverse effects.

Who to refer TMD patients to?

Situations when it is recommended that dental practitioners consider referring TMD patients to a physical therapist.

How to relieve TMD pain?

Patients with TMD tend to report that their pain is intensified by events such as stress, clenching, and eating, while it is relieved by relaxing, applying heat to the painful area, and taking over-the-counter analgesics1,4,5,10.

How many people have TMD?

Approximately 33% of the population has at least one TMD symptom and 3.6% to 7% of the population has TMD with sufficient severity to cause them to seek treatment1–3. TMD is often viewed as a repetitive motion disorder of the masticatory structures.

What is atemporomandibular disorder?

Atemporomandibular disorder (TMD) is a musculoskeletal disorder within the masticatory system. Many practitioners refer to TMD as a single disorder in spite of the fact that patients have various sub-diagnoses (e.g., myofascial pain, temporomandibular joint (TMJ) inflammation)1,2. TMD is a prevalent disorder most commonly observed in individuals ...

What are the contributing factors to TMD?

Examples of commonly identified TMD perpetuating factors are nighttime parafunctional habits, gum chewing, daytime clenching, holding tension in the masticatory muscles, neck pain, excessive caffeine consumption, stress, tension, aggravations, frustrations, depression, poor sleep, poor posture, and widespread pain . It is recommended that the contributing factors that are the easiest to change and that are speculated to provide the greatest impact on the symptoms be initially changed1,2,4,17,24.

What is the dental exam for TMD?

As part of the clinical exam, it is recommended that dental practitioners visually perform an intraoral screening, evaluating for evidence of pathology, such as swelling, cavities, deflection of the soft palate when saying “ah,” etc. The patient's history will often have alerted the practitioner to oral disorders that may be causing or contributing to the symptoms and which may indicate that additional radiographs or tests are needed. Generally, only a screening radiograph, such as a panoramic radiograph, is needed in the evaluation of the majority of TMD patients2,5,17,18.

Where is TMD pain located?

TMD pain is generally located in the masseter muscle, preauricular area, and/ or anterior temporalis muscle regions. The quality of this pain is generally an ache, pressure, and/or dull pain and may include a background burning sensation.

What is TMJ medicine?

Medications for Temporomandibular Joint Disorder . Temporomandibular Joint Disorder (TMJ) is pain and swelling of the jaw joints. TMJ is usually caused by teeth grinding and tight jaw muscles due to stress. TMJ may also be caused by injury to the jaw, poorly fitting dentures, and arthritis.

Does a drug have multiple schedules?

The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.

What is the best treatment for TMD?

Nonsteroidal anti-inflammatory drugs should be recommended for initial pharmacotherapy of TMD. The addition of a muscle relaxant is recommended if there is clinical evidence of muscle spasm.

How many patients require TMD treatment?

Only 5% to 10% of patients require treatment for TMD, and 40% of patients have spontaneous resolution of symptoms. 25 In a long-term follow-up study, 50% to 90% of patients had pain relief after conservative therapy. 26 A multidisciplinary approach is successful for the management of TMD. Initial treatment goals should focus on resolving pain and dysfunction. More than 1,500 persons in an online TMD registry reported that they had received anti-inflammatory agents (73%), nonprescription pain relievers (56%), antidepressants (50%), opioids (48%), anxiolytics (41%), and muscle relaxants (40%). 27 Surgical interventions were reserved for patients whose symptoms did not improve after a trial of conservative therapy. Figure 2 presents an abbreviated treatment algorithm for the nonsurgical management of TMD.

What is the TMD in the head?

Temporomandibular disorders (TMD) are characterized by craniofacial pain involving the joint, masticatory muscles, or muscle innervations of the head and neck. 1 TMD is a major cause of nondental pain in the orofacial region.

What is temporomandibular disorder?

Temporomandibular disorders (TMD) are a heterogeneous group of musculoskeletal and neuromuscular conditions involving the temporomandibular joint complex, and surrounding musculature and osseous components. TMD affects up to 15% of adults, with a peak incidence at 20 to 40 years of age. TMD is classified as intra-articular or extra-articular.

What is the TMJ?

The temporomandibular joint (TMJ) is formed by the mandibular condyle inserting into the mandibular fossa of the temporal bone. Muscles of mastication are primarily responsible for movement of this joint ( Figure 1). Temporomandibular disorders (TMD) are characterized by craniofacial pain involving the joint, masticatory muscles, ...

How to diagnose TMD?

The diagnosis of TMD is based largely on history and physical examination findings. The symptoms of TMD are often associated with jaw movement (e.g., opening and closing the mouth, chewing) and pain in the preauricular, masseter, or temple region. Another source of orofacial pain should be suspected if pain is not affected by jaw movement. Adventitious sounds of the jaw (e.g., clicking, popping, grating, crepitus) may occur with TMD, but also occur in up to 50% of asymptomatic patients. 1 A large retrospective study (n = 4,528) conducted by a single examiner over 25 years noted that the most common presenting signs and symptoms were facial pain (96%), ear discomfort (82%), headache (79%), and jaw discomfort or dysfunction (75%). 13 Other symptoms may include dizziness or neck, eye, arm, or back pain. Chronic TMD is defined by pain of more than three months' duration.

What is the etiology of TMD?

The etiology of TMD is multifactorial and includes biologic, environmental, social, emotional, and cognitive triggers. Diagnosis is most often based on history and physical examination. Diagnostic imaging may be beneficial when malocclusion or intra-articular abnormalities are suspected.

What is TMD in medical terms?

Temporomandibular disorders (TMD) refer to an orofacial (face, head, or neck) pain condition in which pain and discomfort affect the temporomandibular joint (TMJ), the muscles, or the contiguous tissue components.

What are the parts of the TMJ?

The TMJ is composed of three parts. Credit: NIH/NIDCR. Mandibular condyle - the part of the joint located in the lower jaw. Glenoid fossa - the part of the joint located at the base of the skull. Meniscus - a small disc-shaped piece of cartilage, which serves as a cushion between the mandibular condyle and glenoid fossa.

Where is the TMJ implant?

FDA-approved devices for TMD, including TMJ implants. The TMJ is the part of the lower jaw, in front of the ear where the lower jaw connects to the to the skull. There is a TMJ on each side of the jaw. The TMJ is composed of three parts. Credit: NIH/NIDCR. Mandibular condyle - the part of the joint located in the lower jaw.

Is TMD a surgical condition?

TMD is a complex medical condition which can be difficult to treat. Non-surgical treatment options include: Surgical treatment options, which are more invasi ve, include: TMJ implants are intended to be implanted in the jaw to replace all or part of the temporomandibular joint.

What is the best medicine for TMJ pain?

NSAIDs are commonly used to relieve the pain and inflammation in the TMJ and muscles of the jaw, face, and neck.#N#Examples: aspirin, celecoxib (Celebrex), diclofenac (Voltaren), ibuprofen (Motrin, Advil), naproxen (Aleve)

How long does it take for corticosteroids to help with TMJ?

Evidence: There is good evidence that corticosteroids can help with TMJ pain over a period of 4–6 weeks, but…

How long does it take for capsaicin to help with TMJ pain?

Evidence: A small study showed some TMJ pain relief after a 1-week period following a single topical application of 8 percent capsaicin cream, but further studies with additional patients are needed to confirm this finding.

Why does TMJ hurt?

Much of the pain TMJ sufferers experience is thought to be caused by tight, overactive muscles in the jaw and face. Muscle relaxants act as a central nervous system depressants and have sedative and musculoskeletal relaxant properties.

What is the best medication for neuropathy?

Anticonvulsants commonly used to treat neuropathic (nerve) pain have been found to be effective in the treatment of certain chronic pain disorders such as fibromyalgia, diabetic neuropathy or postherpetic neuralgia. Examples: gabapentin (Neurontin), pregabalin (Lyrica).

What can I take to help my jaw hurt?

Medications. For many people, short-term use of over-the-counter pain medications or nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may provide temporary relief from jaw and muscle discomfort. If pain persists, your medical provider can prescribe stronger pain or anti-inflammatory medications, muscle relaxants, ...

Does codeine help with TMJ pain?

Evidence: One randomized trial with 80 subjects provided moderate evidence that a combination analgesic product (NSAID and low-dose codeine) delivered relief from pain associated with TMJ (Shaheed et al., 2019). A recent review identified placebo-controlled studies that reported improved outcomes with morphine and fentanyl for TMJ arthrocentesis (NAM 5-20). Currently, while there are a number of studies showing benefits from opioids during the short period (i.e. weeks to months), there is little data informing us about the long term benefits of opioids in chronic pain. We need much more research on this topic, particularly in TMJ disorders.

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Overview

Causes

Classification

Diagnosis

Clinical significance

Management

Treatment

Introduction

Uses

Medical uses

Research

  • There has been a limited number of studies investigating the effectiveness of onabotulinumtoxinA (Botox) in the management of TMD.53 Early small randomized controlled trials have shown promising results for the improvement of painful myofascial symptoms.5456 However, a recent Cochrane review (four studies, N = 233) found inconclusive evidence to su...
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