Is PC-SPES safe for prostate cancer patients?
Although PC-SPES has been studied in prostate cancer patients, the product was recalled due to product contamination. PC-SPES is an herbal formula containing 8 herbs: reishi mushroom, baikal skullcap, rabdosia, dyer’s woad, chrysanthemum, saw palmetto, Panax ginseng, and licorice.
Is PCPC-Spes still available?
PC-SPES is no longer available. Manufacturers market PC-HOPE, PC-CARE and PC-PLUS as herbal products to promote prostate health and to treat prostate cancer. There is no reliable scientific evidence to use it as a cancer treatment. PC-SPES was a mixture of eight herbs. It included:
What is PC-SPES prostate formulation?
PC-SPES Prostate Formulation. A study was conducted to identify all active principles in the herbal composition. Study concluded that PC-SPEC was in fact contaminated with various synthetic prescription drugs. Substances like warfarin, indomethacin, and diethylstilbestrol were all found in PC-SPES batches from various time frames.
How are DU-145 tumors treated with PC-SPES?
Treatment with PC-SPES began the day after injection. Results showed that PC-SPES suppressed the growth of DU-145 tumors compared with tumor growth in the control group. Cytological analysis showed apoptosis in the treated group that was not apparent in the control group. [ 10]
What is the herb PC-SPES?
PC-SPES is a supplement consisting of eight herbs: reishi mushroom, baikal skullcap, rabdosia, dyer's woad, chrysanthemum, saw palmetto, Panax ginseng, and licorice. Laboratory studies suggested it may have anticancer effects, particularly against prostate cancer.
What does PC stand for cancer?
PC stands for prostate cancer and SPES is the Latin word for hope. PC-SPES was available over the counter in the USA from 1996. But the American Food and Drug Regulation Agency (FDA) withdrew it in 2002. The FDA found warfarin in samples of PC-SPES. Warfarin is a drug that helps to stop blood from clotting.
How to detect prostate cancer?
A biopsy is the main tool for diagnosing prostate cancer, but a doctor can use other tools to help make sure the biopsy is made in the right place. For example, doctors may use transrectal ultrasound or magnetic resonance imaging (MRI) to help guide the biopsy.
Is adenocarcinoma of the prostate an aggressive cancer?
1. What is "adenocarcinoma of the prostate"? Adenocarcinoma of the prostate is a type of cancer (tumor) with a wide range of behavior from cases which are very slow growing with a low risk of causing men harm to cases which are more aggressive.
What does malignant neoplasm of prostate mean?
Malignant neoplasms are cancerous tumors. They develop when cells grow and divide more than they should. Malignant neoplasms can spread to nearby tissues and to distant parts of your body. Treatment options may include surgery, chemotherapy or radiation therapy.
What is the newest treatment for prostate cancer?
The treatment is called lutetium-177-PSMA-617, or LuPSMA, and it has two components: a compound that targets a cancer cell protein called prostate-specific membrane antigen, or PSMA, and a radioactive particle that destroys the cells.
What are the 7 warning signs of prostate cancer?
Early prostate cancer symptomsBurning or pain during urination.Difficulty urinating, or trouble starting and stopping while urinating.More frequent urges to urinate at night.Loss of bladder control.Decreased flow or velocity of urine stream.Blood in urine (hematuria)Blood in semen.Erectile dysfunction.More items...
What are the 5 warning signs of prostate cancer?
5 Warning signs are bone pain, compression of the spine, Painful urination, erectile dysfunction, and blood in the urine.
What are the drugs in PC-SPES?
Tests found that some batches of PC-SPES contained one or more of the following drugs, which are not found in nature: DES, a type of estrogen made in a lab. Warfarin (Coumadin), a blood-thinner. Indomethacin, a drug used to decrease inflammation.
What are the side effects of PC-SPES?
There were other, less common, side effects: Blood clots in the legs. Diarrhea. PC-SPES may also change the way drugs, including anticancer drugs, work in the body. It may cause drugs to be more or less effective, or cause effects on the body that are not expected.
What is PC SPES used for?
Herbs in PC-SPES have been used in traditional Chinese medicine for many health problems, including prostate problems, for hundreds of years (see Question 2 ). The herbs used in PC-SPES have been reported to help keep cancer cells from growing or help prevent cell damage that can lead to cancer (see Question 3 ).
What is PDQ cancer?
This PDQ cancer information summary has current information about the use of PC-SPES in the treatment of people with cancer. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care.
What is clinical trial?
A clinical trial is a study to answer a scientific question, such as whether one treatment is better than another. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients. During treatment clinical trials, information is collected about the effects of a new treatment and how well it works. If a clinical trial shows that a new treatment is better than one currently being used, the new treatment may become "standard." Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment.
Does PC-SPES slow prostate growth?
Laboratory and animal studies suggested that PC-SPES might slow the growth of prostate cancer cells, but it is not known if these results were caused by the herbs in PC-SPES, prescription medicines that were found in the mixture, or both (see Question 5 ). Clinical trials suggested that PC-SPES lowers PSA (prostate specific antigen) ...
Does PC-SPES work?
It is not known how PC-SPES works in the body. Some of the herbs in the mixture contain phytoestrogens, which are estrogen-like substances found in plants. Estrogen can cause the testicles to stop making testosterone, which makes some prostate cancers grow.
What is the botanical in PC-SPES?
Considerable research has been conducted on the anticancer properties of the eight individual botanicals in PC-SPES. Baikal skullcap ( Scutellaria baicalensis )—Chinese name huang qin—contains baicalin and wogonin, two active flavones. Baicalin converts to baicalein, which is another active flavone.
When was PC-SPES patented?
In 1997 , the herbal formula for PC-SPES was patented in the United States. [ 1] A company, BotanicLab (Brea, California), was formed to produce, distribute, and sell the product. PC-SPES was sold through the BotanicLab website (the website was taken down after PC-SPES was recalled) and through selected distributors. Anecdotal information about the product and its positive effects was widely circulated on the Internet through websites that informed prostate cancer patients about new developments in treatment. At the same time, the published papers were being read by the scientific community, and the findings were presented at various conferences. As a result, clinicians and researchers began looking at PC-SPES as one of the first viable treatments to come out of the alternative medicine community.
What is PDQ cancer?
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of PC-SPES in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
How does PC-SPES work?
Exactly how PC-SPES works in the body is still unknown. The presence of adulterants and varying amounts of the active agents in each lot of PC-SPES complicates the interpretation of any results from studies that might lead to an explanation of its mechanisms of action.
What is TCM in plant products?
TCM has different names for the medicinals coming from the leaf, stem, and root and uses these plant products for different purposes. Indirubin, an active ingredient, and its analogs have demonstrated inhibition of cyclin-dependent kinases in human mammary carcinoma cell line MCF-7 in vitro .
What is a PC-SPES summary?
This cancer information summary provides an overview of the use of PC-SPES as a treatment in people with cancer. The summary includes a brief history of PC-SPES research, the results of clinical trials, and possible adverse effects of PC-SPES. Included in this summary is a discussion of the contamination of PC-SPES and its withdrawal from avenues of distribution.
Why was PC-SPES recalled?
PC-SPES was recalled and withdrawn from the market because certain batches were contaminated with Food and Drug Administration–controlled prescription drugs.
What is PC SPES?
PC-SPES, PC-HOPE, PC-CARE and PC-PLUS are herbal supplements marketed as a way to promote prostate health and treat prostate cancer. PC-SPES is no longer available. There is not enough reliable evidence to use the other three products as a cancer treatment.
Why do people use PC-SPES?
People used PC-SPES to treat prostate cancer treatment because several trials had positive results. The trials looked at different herbs as a possible treatment for prostate cancer. It showed that the herbs seemed to act as a type of hormone therapy that could help to treat prostate cancer.
Can you use herbal products for prostate cancer?
you might want to wait and use them later, in case other hormone therapies stop working for you. your specialist needs to know what you're taking to have a full picture of your treatment. Using these herbal products instead of conventional treatments for prostate cancer could be very har mful to your health.
Is PC SPES still available?
PC-SPES is no longer available. Manufacturers market PC-HOPE, PC-CARE and PC-PLUS as herbal products to promote prostate health and to treat prostate cancer. There is no reliable scientific evidence to use it as a cancer treatment.
Can PC Hope be used for prostate cancer?
The trials suggested that they might lower PSA levels and improve quality of life. A laboratory study looked at using PC-HOPE for pancreatic cancer.
Is PC-SPES anti-cancer?
The studies had positive results. But researchers say that it is not possible to tell if these results are accurate.
Is PC-SPES legal in the US?
Indomethacin is an anti-inflammatory drug. It is in the same drug family as ibuprofen (Nurofen). PC-SPES is not legally available in the United States. The manufacturer that had a license from the patent holder is no longer in business.
Does PC-SPES affect PSA?
Clearly PC-SPES has a strong effect on PSA Levels. A prospective trial with a total of 70 prostate cancer patients that were either androgen-dependent or androgen-independent were given 9 capsules of PC-SPES daily. Results showed that 100% of androgen-dependent patients had a PSA decline that was greater or equal to 80%. And 54% of the androgen-independent patients had PSA decline of greater or equal to 50%. Study also concluded that reduction of PSA levels were also accompanied by possible anticancer response due to tumor shrinkage, improved bone scans, and stable disease experienced by some patients.
Does PC-SPEC have anticancer?
Studies did show that PC-SPEC did in fact have anticancer and PSA lowering effects. However, because the formulation was so inconsistent and known to be contaminated, no one knows what caused the positive effects. Was it the contaminated prescription drugs that lowered PSA levels? Or was is truly the combination of the 8 herbs? Or maybe it’s the combination of both? Because of these unknowns and inconsistencies, we can’t purely judge PC-SPES on the positive results shown in studies. A constant changing formulation is impossible to replicate. If anything, the studies don’t mean anything except that more testing needs to be done with a standardized formulation. Only then we can get a definitive answer. Trying to replicate the positive results seen in these studies yourself looks like nothing but high risk and dangerous.
The Paxman Scalp Cooling System is globally recognized as the leading product for hair-loss prevention during chemotherapy treatment for breast cancer
The Paxman Scalp Cooling System is globally recognized as the leading product for hair-loss prevention during chemotherapy treatment for breast cancer.
The Paxman Scalp Cooling System is available in 2 models to allow either 1 patient to be treated or 2 patients to be independently treated at the same time
The Paxman Scalp Cooling System offers many benefits for use in hospitals, chemotherapy clinics, or healthcare facilities.
The most important feature of the Paxman Scalp Cooling System is the lightweight design of the personal single-patient-use cap
Manufactured from medical-grade, soft-silicone material, the cap is light, yet flexible and strong, and easy to use. The Paxman Cap provides a close fit around the patient’s head. After extensive anthropometric research regarding head shapes, 3 different cap sizes were developed to meet the needs of all patients.
Where can you find tumor markers?
Some of these markers are specific to one cancer. Some are seen in several types of cancer. The markers can be found in the blood, urine, or tissues.
What percentage of colon cancers have a raised CEA?
For example, carcinoembryonic antigen (CEA) is a tumor marker used in colon cancer, yet only 70-80% of colon cancers make CEA. This means 20-30% of people with colon cancer will not have a raised CEA level. Only 25% of early stage colon cancers have a raised CEA. Because of this, CEA cannot always help find colon cancer in its early stages, ...
What is the purpose of a prostate cancer screening test?
The goal of a screening test is to find cancer early, when it is the most treatable and before it has had a chance to grow and spread. So far, the only tumor marker to gain some approval as a screening tool is the Prostate Specific Antigen (PSA) for prostate cancer, though this has concerns as well.
Can CEA be used to detect colon cancer?
Only 25% of early stage colon cancers have a raised CEA. Because of this, CEA cannot always help find colon cancer in its early stages, when cure rates are best. The bottom line is, tumor markers can be very helpful in watching a person's response to treatment and, in some cases, watching for the cancer to return.
Can you watch tumor markers after cancer treatment?
In breast cancer, research has found that watching tumor markers after treatment does not help people live longer. For that reason, they are not recommended. Tumor markers can also be used along with other tests (scans, biopsies, and so on) to help find cancer in a patient who has symptoms that are suspicious for cancer.
Eye Conditions
Anyone who reads for hours, works at a computer, or drives long distances knows about this one. It happens when you overuse your eyes. They get tired and need to rest, just like any other part of your body.
RADIATION - The Silent Killer
Electric and magnetic fields (EMF) are invisible areas of energy (also called radiation) that are produced by electricity, which is the movement of electrons, or current, through a wire.
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What is PCs for people?
PCs for People provides free pick up and recycling of electronic waste from businesses, educational and governmental organizations. PCs for People is the only recycling business in Minnesota and one of only two in Colorado that has both NAID AAA and R2 certifications, meaning your data is protected through strict adherence to the highest standards of information destruction, hard drive sanitization, and all recycling is environmentally responsible. Since PCs for People accepts nearly all electronic waste - including computers, peripherals, monitors, cables, drives, and more - you need just one company.
Is PCs for People a recycling company?
PCs for People is the only recycling business in Minnesota and one of only two in Colorado that has both NAID AAA and R2 certifications, meaning your data is protected through strict adherence to the highest standards of information destruction, hard drive sanitization, and all recycling is environmentally responsible.
What Is PC-SPES, Pc-Hope, PC-Care and Pc-Plus?
Why People with Cancer Use It
How You Have It
- There's no medically approved dose for these herbal products. There are guidelines published by suppliers of the herbs. You take them as tablets or capsules that you swallow. They come in various doses.
Side Effects
- PC-SPES caused some side effects. It acted like oestrogen. So, the side effects were the same as for other oestrogen based hormone therapies and included: 1. nipple tenderness 2. feeling sick 3. fatigue 4. diarrhoea 5. leg cramps/swelling 6. hot flushes 7. loss of sex drive Less common side effects included: 1. an increased risk of blood clots in the legs 2. breast swelling 3. erection diffi…
Research Into PC-SPES, Pc-Hope, PC-Care and PC-Plus and Cancer
- PC-SPES
The developer of PC-SPES did many laboratory and animal studies on the herbs used in the product. They looked at the anti-cancer qualities of the herbs for prostate cancer. The studies had positive results. But researchers say that it is not possible to tell if these results are accurate. Th… - PC-HOPE
PC-HOPE, PC-CARE and PC-PLUS are very similar products. Researchers did laboratory studies on PC-HOPE and PC-SPES. It showed that they might be active against prostate cancer cells. Two studies looked at using them in men with prostate cancer. The trials suggested that they might l…
How Much It Costs
- You can buy PC-HOPE, PC-CARE and PC-PLUS from nutritionists and manufacturers. The price can vary depending on: 1. the dose 2. the amount you buy 3. where you buy it (health food shops, chemist or online)
A Word of Caution
- It is understandable that you might want to try anything if you think it might help treat or cure your cancer. Only you can decide whether to use an alternative cancer therapy such as PC-HOPE, PC-CARE or PC-PLUS. You could harm your health if you stop your cancer treatment for an unproven treatment. Many websites might promote these supplements as a cure for cancer. But no reputa…