What are the side effects of radioactive iodine therapy?
Temporary side effects of RAI may include:
- Neck tenderness and swelling.
- Nausea.
- Swollen salivary glands.
- Loss of taste or taste change.
- Dry mouth/insufficient salivary production.
- Dry eyes.
- Excessive tearing from the eyes.
How much does radioactive iodine treatment cost?
Thyroid cancer treatment typically is covered by health insurance, although some plans may not cover certain drugs or treatments. For patients without health insurance, thyroid cancer treatment typically costs from about $20,000-$40,000 for surgery and up to $4,000 for radioactive iodine treatment, which is often recommended for thyroid cancer.
What are the long term effects of radioactive iodine?
After radioactive iodine treatment for thyroid cancer
- Thyroid medicine after radioactive iodine treatment. You may have stopped taking your thyroid hormone tablets in preparation for your treatment. ...
- Radiation safety precautions. ...
- Travelling after radioactive iodine treatment. ...
- Possible short term side effects. ...
- Possible long term side effects
- Further radioactive iodine treatments. ...
How do you clean after radioactive iodine treatment?
- Avoiding physical contact with other members of the household, including sleeping alone
- Flushing your toilet twice after every use
- Washing your hands frequently with decontamination soap
- Avoiding cooking for others
- Using plastic gloves to cook
- Keeping all clothing and linens separate from the rest of the household
Which is better thyroid surgery or radioactive iodine?
Surgery for hyperthyroidism was associated with a lower risk of all-cause and cardiovascular death as compared to radioactive iodine therapy during long-term follow-up, particularly in men.
What is iodine radiation used for?
Currently, radioactive iodine therapy is only used to treat hyperthyroidism (overactive thyroid gland) and certain types of thyroid cancer. It's also used to help determine the root causes of hyperthyroidism and to see if certain thyroid cancers have spread to other parts of the body.
Is radioactive iodine treatment common?
RAI, which has been used widely in the United States for the treatment of hyperthyroidism since the 1940s, is one of three commonly used treatments for hyperthyroidism.
How long do you have to be in isolation after radioactive iodine?
You are also required to self isolate for 7 days after your radioiodine treatment in order to minimise the risk of contracting COVID-19 whilst there is still a large amount of radioactivity in your body. A small proportion of people with COVID-19 may become very unwell and require admission to hospital.
Who needs radioactive iodine?
Because of this, radioactive iodine (RAI, also called I-131) can be used to treat thyroid cancer. The RAI collects mainly in thyroid cells, where the radiation can destroy the thyroid gland and any other thyroid cells (including cancer cells) that take up iodine, with little effect on the rest of your body.
What causes thyroid problems?
Problems with the thyroid can be caused by: iodine deficiency. autoimmune diseases, in which the immune system attacks the thyroid, leading either to hyperthyroidism (caused by Graves' disease) or hypothyroidism (caused by Hashimoto's disease) inflammation (which may or may not cause pain), caused by a virus or ...
Does radioactive iodine shorten your life?
Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery.
Can your thyroid come back after radioactive iodine?
Early recurrences are reported in 20–54% of cases within 3–6 months, which can be due to inadequate RAI treatment or early Marine Lenhart syndrome. True recurrence is relapse after an extended period of time following attainment of hypothyroidism.
What are the long term side effects of radioactive iodine?
Possible long term side effects include:Ability to have children (fertility) Some women may have irregular periods after radioactive iodine treatment. ... Inflammation of the salivary glands (where spit is made) ... Tiredness. ... Dry or watery eyes. ... Lower levels of blood cells. ... Lung problems. ... Second cancers.
Do I have to stay in hospital for radioactive iodine?
Having radioactive iodine treatment for thyroid cancer. Radioactive iodine treatment takes place in the hospital. You usually stay there for a few days until your radiation levels have fallen to a safe level. You will be looked after in a single room, where you stay alone.
Is it safe to be around someone after radioactive iodine treatment?
Keep Your Distance Here are some ways to minimize radiation risks to other people (and pets) after you have had RAI treatment: Stay at least six feet away from other people, including members of the public, family members, and co-workers, for three to 11 days.
Can you drive after radioactive iodine treatment?
Radioactive iodine gives off radiation. This means that after your treatment, you won't be able to go home using public transportation such as buses, the subway, trains, or a plane. You can drive yourself home, have someone pick you up and take you home, or take a taxi or private car home.
What is the radiation used for thyroid cancer?
The radiation dose used here is much stronger than the one used in radioiodine scans, which are described in Tests for Thyroid Cancer. This treatment can be used to ablate (destroy) any thyroid tissue not removed by surgery or to treat some types of thyroid cancer that have spread to lymph nodes and other parts of the body.
How long after radiation therapy can you go home?
Depending on the dose of radioiodine used and where you are being treated, you might need to be in the hospital for a few days after treatment, staying in a special isolation room to prevent others from being exposed to radiation. Some people may not need to be hospitalized. Once you are allowed to go home after treatment, you will be given instructions on how to protect others from radiation exposure and how long you need to take these precautions. These instructions may vary slightly by treatment center. Be sure you understand the instructions before you leave the hospital.
How long should I take thyrotropin before RAI?
Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day. Most doctors also recommend that you follow a low iodine diet for 1 or 2 weeks before treatment.
How to treat RAI?
For RAI therapy to be most effective, you must have a high level of thyroid-stimulating hormone (TSH or thyrotropin) in the blood. This hormone is what makes thyroid tissue (and cancer cells) take up radioactive iodine. If your thyroid has been removed, there are a couple of ways to raise TSH levels before being treated with RAI: 1 One way is to stop taking thyroid hormone pills for several weeks. This causes very low thyroid hormone levels (hypothyroidism), which makes the pituitary gland to release more TSH. This intentional hypothyroidism is temporary, but it often causes symptoms like tiredness, depression, weight gain, constipation, muscle aches, and reduced concentration. 2 Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day.
Can you use rai for thyroid cancer?
Discuss your risks and benefits of RAI therapy with your doctor. Radioactive iodine therapy cannot be used to treat anaplastic (undifferentiated) and medullary thyroid carcinomas because these types of cancer do not take up iodine.
Can radiation cause irregular periods?
Radioactive iodine may also affect a woman’ s ovaries, and some women may have irregular periods for up to a year after treatment.
Does radioactive iodine help with thyroid cancer?
Radioactive iodine therapy helps people live longer if they have papillary or follicular thyroid cancer (differentiated thyroid cancer) that has spread to the neck or other body parts, and it is now standard practice in such cases. But the benefits of RAI therapy are less clear for people with small cancers of the thyroid gland ...
What is iodine used for?
Iodine, in the form of iodide, is made into two radioactive forms of iodine that are commonly used in patients with thyroid diseases: I-123 ( harmless to thyroid cells) and I-131 ( destroys thyroid cells ). The radiation emitted by each of these forms of iodine can be detected from outside the patient to gain information about thyroid function ...
Why is iodine important for the thyroid gland?
Iodine is essential for proper function of the thyroid gland, which use s it to make the thyroid hormones. The thyroid is equipped with an active system or “pump” for moving iodine into its cells, where it is concentrated as iodide. The thyroid gland is the only tissue in the body that takes up and holds onto iodine.
What is the I-123 isotope used for?
I-123 is the usual isotope used to take pictures and determine the activity of the intact thyroid gland ( Thyroid Scan and Radioactive Iodine Uptake, RAIU ), since it is harmless to thyroid cells. No special radiation precautions are necessary after a thyroid scan or RAIU using I-123. I-131 can also be used to take pictures of the thyroid gland, ...
What is the purpose of I-131?
THYROID CANCER – Large doses of I-131 are used to destroy thyroid cancer cells (see Thyroid Cancer brochure ). This is performed after the remaining thyroid cells ( including any cancer cells) are stimulated by raising TSH levels by either withdrawing the thyroid hormone pills or by treating with recombinant human TSH.
Is rai safe for X-rays?
RAI is safe to use in individuals who have had allergic reactions to seafood or X-ray contrast agents, since the reaction is to the compound containing io dine, not the iodine itself. RAI is given by mouth in pill or liquid form.
When can you stop breast feeding after I-131?
This protects the baby who would otherwise receive radioactive milk and the mother’s breasts which concentrate RAI. Breastfeeding must be stopped at least 6 weeks before administration of I-131 treatment and should not be restarted after administration of RAI, but can be safely done after future pregnancies.
Can RAI cause thyroid cancer?
Hypothyroidism is a common side effect of RAI for hyperthyroidism and always seen after RAI for thyroid cancer. This is usually easily treated with thyroid hormone replacement (see Hypothyroidism brochure ). Some studies suggest a slight increase in thyroid cancers may be seen after RAI treatment for hyperthyroidism.
What is radioactive iodine?
Radioactive iodine (iodine-131) therapy is indicated for the management of hyperfunctioning thyroid disease and thyroid cancer. [1][2] It is classified as radioactive nuclear medicine and was first synthesized in 1941, and the FDA approved it in 1971 for its therapeutic use. Its action causes permanent destruction to the thyroid tissue by emitting ...
What is the mechanism of action of iodine?
Iodine is a natural precursor for thyroid hormones triiodothyronine (T3) and thyroxine (T4) and is uptaken from the blood into the thyroid follicular cell by the sodium and iodide transporter.
How does radioactive iodine differentiate thyroid carcinoma?
This differentiation occurs by measuring the uptake of radioactive iodine in the thyroid after 24-hours.
What is the effect of gamma radiation on thyroid?
Its action causes permanent destruction to the thyroid tissue by emitting radiation of two sorts, gamma and beta rays. [3][4] Gamma radiation effects are more useful for diagnostic purposes, whereas beta radiation effects are therapeutic.[4] . Its action is dependant on the uptake of iodine from thyroid tissue and is ineffective in patients ...
What medications are contradicted before therapy?
Medications contradicted before therapy: Antithyroid medication (propylthiouracil, methimazole) Amiodarone. Contrast agents. During radioactive iodine therapy, agents containing iodine can hinder its uptake from the transporter of thyroid cells, as iodine is a natural precursor for thyroid hormones.
How long does RAI therapy last?
Treatment can be started a few days after RAI therapy and should continue for 1 to 3 months. [6][10] The damage to thyroid tissue during radioactive iodine therapy can release thyroid antigens, which may travel to the TSH autoantibodies located in the orbital, causing inflammatory and osmotic effects.[11] .
Can radioactive iodine cause mental retardation?
Vomiting. Diarrhea. The radioactive substance can pass through the placenta and may cause definitive thyroid damage and irreversible mental retardation to the developing fetus. Contraceptive use is a strong recommendation to females of childbearing age who are planning radioactive iodine therapy.
How long does it take for iodine to leave your body?
Most people don't feel different after treatment. But a few people may have nausea. Within a few days after treatment, the radioactive iodine will leave your body in your urine and saliva. How long it takes will depend on your age and on the dose you received.
How long does it take for thyroid to return to normal after iodine?
For most people, one dose of radioactive iodine treatment will cure hyperthyroidism. Usually, thyroid hormone levels return to normal in 8 to 12 weeks. In rare cases, the person needs a second or third dose of radioactive iodine. Risks. Some side effects from radioactive iodine treatment include:
Does radioactive iodine harm thyroid?
After you swallow it, it is taken up by your thyroid gland. Depending on the dosage used, the radioactivity in the iodine destroys most or all of the tissue in your thyroid gland, but it does not harm any other parts of your body.
How long can you live after iodine treatment?
You can expect to live a fairly normal life after radioactive iodine treatment but your life will probably not be exactly as it was before your procedure. For most people, this means that you can expect to live at 80-90% of your 'normal'.
How long does radioactive iodine affect sperm count?
Important to men is the fact that radioactive iodine can cause short-term reductions in sperm count for up to 2 years after your procedure (8). This may or may not be important to you based on your age, your gender, and whether or not fertility is something you are interested in but, again, it's worth knowing about.
Can you take a thyroid pill every day?
There's no way for doctors to give you a pill once a day and for that pill to perform the exact same function that your thyroid gland does every minute of every day. Because of this, people may experience symptoms which may lead them to want to restore whatever thyroid function they can.
Can beta cells take up iodine?
But you probably at least know a little bit about RAI or you wouldn't be here.
Can you gain weight after radioactive iodine treatment?
You may gain weight. This is probably not what you want to hear, especially if this is a procedure that is necessary for your health, but it's still important to know about it. You may gain weight after you undergo radioactive iodine treatment.
How to get rid of radioiodine in urine?
Clean your hands thoroughly every time you use the bathroom. After you go to the bathroom, soap up and scrub your hands thoroughly, as you'll be passing the most radioiodine in your urine. Scrub for at least 20 seconds before rinsing.
How to prevent radioactive particles in the house?
1. Wash your linens and clothes separately from the rest of the household. Always wash your towels, sheets, and clothes in a different load from other household items. They may spread radioactive particles to other items in the house if you don't take this precaution.
How to keep dishes from spreading radioactive particles?
2. Wash your dishes separately from the rest of the dishes. Reserve dishes and utensils for yourself that only you use, kept away from other dishes and utensils. Also, wash these items separately from other household dishes so you don't spread radioactive particles to other items.
Can you get radioactive iodine if you have thyroid cancer?
If you're being treated for hyperthyroidism or thyroid cancer, you may be given radioactive iodine or radioiodine. [1] With this treatment, it's possible to contaminate others with radiation, even though the amount of radiation you're given is fairly small.
Can radiation contaminate other people?
With this treatment, it's possible to contaminate others with radiation, even though the amount of radiation you're given is fairly small. For that reason, take precautions to clean up after yourself, particularly in the bathroom and the kitchen, and to isolate items you use from other household items.
Can you shower with radioiodine?
Showering helps wash away what your body's shedding each day in radioiodine. However, skip baths, as you'd just be soaking in radioiodine. Plus, you're more likely to leave radioiodine behind in the bathtub. ...
