when did you need the promethazie before treatment

When should I take promethazine for surgery?

When used for surgery, promethazine is usually taken the night before the surgery. How often you take this medicine and the timing of your dose will depend on the condition being treated. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup.

Is promethazine safe for a 2 year old?

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age.

What is promethazine used to treat?

Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid. Promethazine is not for use in treating symptoms...

Can promethazine be used to treat morning sickness or motion sickness?

The same would apply to the use of promethazine in treating morning sickness or motion sickness. Because of its sedating effect, promethazine should only be used if other conservative therapies are unable to relieve nausea symptoms.

What conditions require promethazine?

Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products.

Can you take promethazine as needed?

Typical dosing for promethazine Allergies: Promethazine can be taken a few different ways to treat allergies. You can take 25 mg by mouth or rectally at bedtime OR 12.5 mg by mouth or rectally before meals and at bedtime OR 6.25 to 12.5 mg by mouth or rectally 3 times a day as needed.

When should I take promethazine for anxiety?

For control of pain or anxiety before or after surgery: Adults and teenagers—50 mg the night before surgery; 25 to 50 mg after surgery. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child.

What is the indication of promethazine?

Promethazine tablets and suppositories are indicated to treat rhinitis, allergic conjunctivitis, allergic reactions to blood or plasma, dermographism, anaphylactic reactions, sedation, nausea, vomiting, pain, motion sickness, and allergic skin reactions.

What is promazine used to treat?

Promazine is a phenothiazine used to manage schizophrenia. A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.

How long does promethazine stay in your system?

Urine: 2 to 3 days. Blood: Up to 24 hours. Saliva: 1 to 4 days.

Does promethazine calm you down?

This medicine works wonders for nausea, plus it has a calming effect as well.

Does promethazine help panic attacks?

Promethazine is used to treat several conditions, including allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. It's also used as a sleep aid, including before and after surgery. This drug may be used as part of a combination therapy.

Why does promethazine cause sedation?

Promethazine also blocks the action of acetylcholine (anticholinergic effect), and this may explain its benefit in reducing the nausea of motion sickness. It is used as a sedative because it causes drowsiness as a side effect. The FDA approved promethazine in 1951.

Before Taking This Medicine

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young child...

How Should I Take Promethazine?

Take promethazine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...

What Happens If I Overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include overactive reflexes, loss of coordina...

What Should I Avoid While Taking Promethazine?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fas...

Promethazine Side Effects

Get emergency medical help if you have any signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throa...

Promethazine Dosing Information

Usual Adult Dose of Promethazine for Anaphylaxis:Parenteral: 25 mg IV or IM once, followed by close observation for response. This dose may be repe...

What Other Drugs Will Affect Promethazine?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can...

Why is promethazine not recommended for children?

Use of promethazine injection is not recommended in children younger than 2 years of age because of the increased risk of respiratory depression.

Can you take two different medicines at the same time?

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.

Can elderly people take promethazine?

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of promethazine injection in the elderly. However, elderly patients may be more sensitive to the side effects of this medicine than in younger adults, and are more likely to have age-related heart or blood vessel disease or prostate problems, which may require an adjustment in the dose for patients receiving promethazine injection.

Can you take a sulfate med with other meds?

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.

What is the purpose of Promethazine?

Promethazine may be used to treat various conditions such as allergies, rhinitis, nausea or vomiting, or insomnia. Promethazine works on histamine-1 (H 1) receptors. H 1 -receptors are present in the bronchial tubes and in the circulatory system.

How long does Promethazine last?

Its effects last for 4-6 hours, although they may persist for up to 12 hours in some people. 7. Interactions. Medicines that interact with promethazine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with promethazine.

How to administer promethazine suppository?

Suppositories are administered into the rectum. Wash your hands and then remove the promethazine suppository from the foil packaging. Moisten the suppository with cold water. Lie down on your side with one knee pulled up to the chest and use your finger to push the suppository into the rectum.

What medications interact with promethazine?

Common medications that may interact with promethazine include: antidepressants, such as amitriptyline, clomipramine, desipramine, doxepin, escitalopram, imipramine, or nortriptyline. antifungals, such as voriconazole. antipsychotics, such as haloperidol, thioridazine, or ziprasidone. barbiturates, such as phenobarbital.

What are the side effects of promethazine?

Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Drowsiness, which may affect a person's ability to drive or operate machinery.

Can promethazine be used during pregnancy?

Symptoms include fever, muscle rigidity, altered mental status, irregular or fast pulse, or cardiac dysrhythmias. Promethazine should only be used during pregnancy if the potential benefits outweigh the risks to the fetus. Use of promethazine within two weeks of delivery may inhibit platelet aggregation in the newborn.

Does Promethazine affect dopamine?

Promethazine can also be used to treat nausea and motion sickness and may have weak effects on other receptors such as dop amine, although this is estimated to be 1/10th that of chlorpromazine. Promethazine belongs to the class of medicines known as phenothiazines. 2. Upsides.

What is Promethazine used for?

Promethazine oral tablet is used to treat several conditions, such as allergies, motion sickness, nausea and vomiting, anxiety before surgery, and pain after surgery. It’s also used as a sleep aid, including before and after surgery.

Why do older people take drugs so slowly?

This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time . This increases your risk of side effects.

What is the class of drugs that are used to treat similar conditions?

Promethazine belongs to a class of drugs called phenothiazines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Promethazine works by preventing the release of a substance called histamine from certain cells in your body.

What to do if you have serious side effects?

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Is Promethazine a generic drug?

Promethazine oral tablet is available as a generic drug only. It doesn’t have a brand-name version. Promethazine comes in four forms: oral tablet, oral solution, injectable solution, and rectal suppository.

Can you give Promethazine to a pregnant woman?

This drug should not be given to a pregnant woman within 2 weeks of delivery because it raises the risk of bleeding in the newborn. For women who are breastfeeding: Promethazine may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.

Does promethazine cause drowsiness?

When you take certain nausea and motion sickness drugs with promethazine, certain side effects may increase and last longer. These side effects include dry mouth, constipation, trouble emptying your bladder, blurred vision, and drowsiness. Examples of these drugs include:

How cold should Promethazine be stored?

Promethazine tablets, syrup, and injection solution should be stored at room temperature between 68 F and 77 F (20 C and 25 C). Keep all forms of this medication away from direct sunlight in their original light-resistant containers.

What is the family of promethazine?

Anaphylaxis (used in adjunct with epinephrine and other medications to counteract the potentially life-threatening hyperallergic reaction) Promethazine belongs to a family of drugs called phenothiazines that also includes Thorazine (chlorpromazine) and Stelazine (trifluoperazine).

Does promethazine cause side effects?

As with any drug, promethazine may cause side effects, particularly in the early stages of treatment. Milder side effects tend to resolve on their own as the body adapts to the medication. Serious ones may require the termination of treatment.

Is promethazine safe for migraines?

Promethazine is also sometimes used off-label to treat migraines. However, this practice has largely fallen out of favor, given the introduction of newer drugs that are not only more effective but have fewer side effects. 5 . The Dangers of Promethazine and "Purple Drank".

Does promethazine slow down motility?

Promethazine blocks other compounds, most notably the neurotransmitter acetylcholine. 1  By doing so, promethazine can slow motility in the gastrointestinal tract. It can also penetrate the blood-brain barrier and act directly on the central nervous system, reducing nausea and delivering mild sedative effects.

Does Promethazine block histamine?

Promethazine is classified as an H1 receptor antagonist, meaning that it blocks the action of histamine. Histamine is an inflammatory compound involved in many immune processes. When released in excess, histamine can cause swelling, itching, sneezing, and other symptoms of allergy.

Can promethazine cause skin darkening?

When used to treat seasonal allergies, promethazine should be reduced to the lowest possible dose once immediate symptoms have been relieved. Prolonged or frequent use can cause skin darkening (hyperpigmentation) and increase the risk of drug allergy even more than a large single dose. 10 

What is the purpose of promethazine?

Promethazine is a first-generation antihistamine of the “phenothiazine” classification often prescribed for the treatment of postoperative nausea, vomiting, and motion sickness. It is commonly utilized as an adjunct to narcotic analgesics to increase their efficacy among those experiencing acute or chronic pain.

How long does it take to get rid of promethazine?

It is important to realize that although systemic elimination of promethazine is likely to occur within 3 and 5 days of a user’s final dose, some users will eliminate it quicker from their systems than others. Not everyone will necessarily eliminate promethazine from their system in an “average” amount of time.

How long does it take for promethazine to clear?

Since most drugs are eliminated quicker when administered intravenously (IV) compared to intramuscularly (IM), it is likely that intravenous users will have cleared promethazine in just over 48 hours, whereas intramuscular users may take over 72 hours to clear it from their systems.

How long does promethazine stay in your system?

This implies that the drug is likely to remain in a user’s system for 3.67 to 4.35 days after administration.

What are the factors that affect the elimination of promethazine?

These factors include things like: a user’s age, body mass, genetics, hepatic function, and renal function. Age: Elderly individuals (over the age of 65) tend to eliminate most drugs slower than younger adults.

Where is promethazine metabolized?

Genetics: It is understood that promethazine is metabolized via enzymes in the liver, principally CYP2D6 isoenzymes. The alleles associated with your CYP2D6 gene will dictate the function of hepatic CYP2D6 isoenzymes.

Does promethazine cause drowsiness?

Despite the significant therapeutic benefit that can be attained from promethazine when utilized properly, it may provoke unwanted side effects such as: brain fog, confusion, fatigue, dizziness, drowsiness, dry mouth, irritability, and tardive dyskinesia.

What is the purpose of promethazine?

Promethazine is used as an anti-histamine and neuroleptic drug, meaning it is used to treat allergies and calm the nervous system respectively. In general, the medication is also used to treat nausea, pain, vomiting, reduce nervousness, motion sickness, etc. Promethazine Overdose is the accidental or intentional intake of ...

What is the cause of promethazine overdose?

Promethazine Overdose is caused by the intake of promethazine drug in dosage that is higher than prescribed. This intake could be accidental, or in some cases intentional, to bring self-harm. The drug is sold as Anergan, Fargan, Phenergan, Promahist, Promethegan, and V-Gan among others.

Why is it important to give your healthcare provider a complete list of prescriptions and non-prescription medications?

It is important to give your healthcare provider a complete list of prescription and non-prescription medications that are being currently taken. This will help them in assessing the possible drug interactions within various medications and help avoid/prevent accidental or unintentional toxic drug effects.

Is Promethazine fatal?

In case of severe symptoms including abnormal heart-rates, seizures, and coma, it may considerably worsen the outcome. Severe cases of Promethazine Overdose are even known to be fatal. In general, overdoses are common situations in the emergency departments.

Allergies

Pediatric

• Appropriate studies have not been performed on the relationship of age to the effects of promethazine injection in the pediatric population. Use of promethazine injection is not recommended in children younger than 2 years of age because of the increased risk of respiratory depression. Caution should be used when this medicine is given to children ...

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Geriatric

Breastfeeding

Drug Interactions

Other Interactions

Other Medical Problems

How It Works

Upsides

Downsides

Tips

Response and Effectiveness

Interactions

Further Information