Treatment FAQ

when allopurinol is used for the treatment of gout, what adverse effect may occur? quizlet

by Berniece Moen Published 2 years ago Updated 2 years ago

Common allopurinol side effects may include: an increase in gout attacks when you first starting taking allopurinol oral; rash; drowsiness;

Full Answer

Can you take allopurinol during an acute attack of gout?

Mar 05, 2021 · Common allopurinol side effects may include: an increase in gout attacks when you first starting taking allopurinol oral; rash; drowsiness; fever, chills; abnormal liver function tests; nausea, diarrhea; or. joint pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What does allopurinol do to your body?

SIDE EFFECTS. -Anorexia, NVD, stomatitis, dizziness, HA, rash, pruritus, malaise, metallic taste, diaphoresis, edema, erectile dysfunction, peripheral neuropathy. ADVERSE EFFECTS. AR. • Cataracts, retinopathy, bradycardia, depression, LT.

How many mg of allopurinol should I take for hyperuricosuria?

Doses of <300 mg may be given a single daily dose. IV: 200 - 400 mg / and square / day, up to 600 mg / day, as a single daily dose or in divided doses Q 8 - 24 HR. Adverse reaction. Cv: hypertension, Flushing, hypertension, bradycardia, and heart failure, reporting with iv administration. CNS: draw a penis.

Does allopurinol interact with other medications or foods?

Life threatening adverse reactions and others Life threatening: Bone marrow depression, aplastic anemia, thrombocytopenia, neutropenia, agranulocytosis, leukopenia Other: Cataracts, retinopathy, bradycardia, depression

What are the adverse effects of allopurinol?

Allopurinol side effects
  • skin rash.
  • diarrhea.
  • nausea.
  • changes in your liver function test results.
  • gout flare-up (if you have gout)

What is the most serious side effect on the use of allopurinol?

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.Jan 29, 2021

What does the drug allopurinol used for gout have to do with the enzymes?

Allopurinol (al' oh pure' i nol) is an analog of hypoxanthine and a potent inhibitor of the enzyme xanthine oxidase that is responsible for converting hypoxanthine to xanthine and xanthine to uric acid in the breakdown pathway of purines.Dec 26, 2020

How does allopurinol cause acute gout?

The most common adverse effect of allopurinol is the precipitation of an acute flare of gout. This is due to urate lowering resulting in urate crystals being shed from articular cartilage into the joint space, resulting in acute inflammation.Feb 21, 2017

What is the best thing to drink if you have gout?

Hence, people with gout should drink coffee with low-fat or skimmed milk and without sugar to prevent attacks. Drinking one to two cups of coffee should do the trick. Lemon water: A study has reported that lemon water or drinks high in vitamin C helps neutralize uric acid in the body.Dec 14, 2021

Should allopurinol be taken in the morning or at night?

Allopurinol Tablets are usually taken once daily. However, if your dose is more than 300mg, your doctor may advise you to take it morning and night after breakfast and dinner for a twice daily dosage. Swallow Allopurinol Tablets with a full glass of water.

What is allopurinol and what is the function of allopurinol?

Allopurinol is a medicine used to lower levels of uric acid in your blood. If you produce too much uric acid or your kidneys do not filter enough out, it can build up and cause tiny, sharp crystals to form in and around your joints. Allopurinol is used to treat gout and kidney stones.

What is the purpose of allopurinol?

Allopurinol is used to prevent or lower high uric acid levels in the blood. It is also used to prevent or lower excess uric acid levels caused by cancer medicines or in patients with kidney stones. A high uric acid level can cause gout or gouty arthritis (joint pain and inflammation).Apr 1, 2022

Does allopurinol damage the kidneys?

Allopurinol can help lower serum urate levels to improve gout symptoms without an increased risk to the kidneys, they concluded. "Our results help to mitigate the concern that allopurinol is harmful to the kidney functioning of patients with gout," said Dr.Nov 12, 2016

When is allopurinol contraindicated?

Allopurinol is not recommended for the treatment of asymptomatic hyperuricemia. Serious toxicity may occur, especially in patients with impaired renal function (see Adverse Events).

Can allopurinol be used in acute gout?

The secondary measures revealed that the acute phase of pain rapidly improved in both groups. Conclusions: We initiated allopurinol at low doses during an acute gout attack in patients who met criteria for starting urate-lowering therapy and did not have abnormal kidney or liver function.

What is the mechanism of action of allopurinol?

Mechanism of Action

Allopurinol and oxypurinol both inhibit xanthine oxidase, an enzyme in the purine catabolism pathway that converts hypoxanthine to xanthine to uric acid.
Jul 7, 2021

Before Taking This Medicine

You should not take allopurinol if you are allergic to it.To make sure you can safely take allopurinol, tell your doctor if you have any of these o...

How Should I Take Allopurinol?

Take allopurinol exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directio...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...

Allopurinol Dosing Information

Usual Allopurinol Adult Dose for Gout:Initial: 100 mg orally once a day.Maintenance: 200 to 300 mg (mild gout) orally once a day or 400 to 600 mg/d...

What Other Drugs Will Affect Allopurinol?

Tell your doctor about all other medicines you use, especially: 1. azathioprine (Imuran); 2. chlorpropamide (Diabinese); 3. cyclosporine (Gengraf,...

What are the most common adverse reactions to gout?

Skin rash is one of the most common adverse reactions and may occur at any time during treatment. Some skin reactions can be severe and sometimes fatal. In patients with the most severe reactions, systemic symptoms such as fever, chills, arthralgia, cholestatic jaundice, eosinophilia and mild leukocytosis, or leukopenia accompany the rash. Among 55 patients with gout who received this drug for an average of 1 year (3 to 34 months), 3% developed pruritic maculopapular skin eruptions, sometimes scaly or exfoliative. The incidence of skin rash appears to be greater in patients with renal insufficiency.

What are the symptoms of a swollen bowel?

increased urination. irritability. joint or muscle pain. large, flat, blue or purplish patches in the skin. light-colored stools. loss of appetite. loss of consciousness. loss of heat from the body. lower back or side pain.

What are the side effects of a syringe?

Side effects requiring immediate medical attention 1 Ankle, knee, or great toe joint pain 2 joint stiffness or swelling 3 rash 4 rash with flat lesions or small raised lesions on the skin

What is the pain in the stomach?

severe stomach pain. slow or irregular heartbeat. sore throat. sores, ulcers, or white spots on the lips or in the mouth. sores, welting, or blisters. stomach pain. sweating. swelling of the face, ankles, hands, or lower legs. swollen or painful glands.

What are the symptoms of a swollen bowel?

increased urination. irritability. joint or muscle pain. large, flat, blue or purplish patches in the skin. light-colored stools. loss of appetite. loss of consciousness. loss of heat from the body. lower back or side pain.

Can medicine cause side effects?

Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:

What are the side effects of a syringe?

unusual bleeding or bruising. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. unusual weight gain or loss. vomiting. vomiting of blood or material that looks like coffee grounds. yellow eyes or skin. Some side effects may occur that usually do not need medical attention.

Can aspirin cause gastric pain?

Increasing the dose of aspirin may lead to gastric distress. Changing the medication regimen is outside of the nurse's scope of practice. A patient has been taking aspirin for chronic pain. The patient states that the pain is not relieved with 650 mg of aspirin every 4 hours.

How do NSAIDs work?

Nonsteroidal anti-inflammatory drugs (NSAIDs) work by blocking cyclooxygenase, the enzyme responsible for conversion of arachidonic acid into prostaglandins. Decreasing the synthesis of prostaglandins results in decreased pain and inflammation.

Can you take aspirin with milk?

Changing to another medication or taking the medication with milk are extreme measures that may not relieve the gastric distress. The nurse is caring for a patient who states, "I can't take aspirin.

How do prostaglandins work?

Nonsteroidal anti-inflammatory drugs (NSAIDs) work by blocking cyclooxygenase, the enzyme responsible for conversion of arachidonic acid into prostaglandins.

What does it mean when your stool is black?

A major side effect of NSAID therapy is gastrointestinal (GI) distress with potential GI bleeding. Black, tarry stools are indicative of a GI bleed. Headaches, cough, and palpitations should not result from the use of NSAID medications.

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