Treatment FAQ

what treatment is there for restless leg syndrome

by Maria Stiedemann Published 2 years ago Updated 2 years ago
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Dopamine agonists: These are most often the first medicines used to treat RLS. These drugs, including pramipexole (Mirapex), rotigotine (Neupro), and ropinirole (Requip), act like the neurotransmitter dopamine in the brain. Side effects include daytime sleepiness, nausea, and lightheadedness.

Medication

 · Restless legs syndrome treatment aims to reduce discomfort from symptoms and improve sleep quality. While RLS symptoms may never fully go away, they can be significantly improved through a combination of lifestyle changes, vitamin and mineral supplements, medical devices, and medication. Establishing a Treatment Plan for Restless Legs Syndrome

Self-care

Other treatment Your doctor may have you try other treatments. These include: A pneumatic compression device. This machine pumps air in and out of sleeves to make them tight and loose around your legs while you are resting. Vibrating pads (Relaxis). The pads send vibrations to your legs. They may improve sleep for some people with RLS. Symptoms

Nutrition

 · Dopamine agonists are often the first drugs used as treatment for restless legs syndrome. Dopamine agonists such as ropinirole, pramipexole, and rotigotine mimic the effects of a chemical called...

What are some natural ways to treat restless leg syndrome?

These might include walking, stretching, taking hot or cold baths, massage, acupressure or relaxation techniques. Identify ways to keep your mind engaged while you are sitting, with activities like discussions, needlework or video games. Avoid nicotine as it is known to disrupt sleep. Implement a program of good sleep habits and coping strategies.

What is the best medication for restless leg syndrome?

58 rows · How is RLS Treated? RLS can be severe in up to 20% of sufferers and medications may be considered if symptoms are severe or distressing and daytime functioning is affected by poor sleep quality. Medications may include: Dopamine agonists Levodopa/carbidopa Gabapentin, Gabapentin enacarbil, pregabalin Iron supplements if there is a deficiency

How to stop RLS naturally?

 · Vitamin D supplements may help relieve symptoms —even just getting outside and soaking up some sun is a good first step. [9] Massage. Try massaging your legs or having a partner massage them for you. [10] If it helps you relax, you can also take a bath and lightly massage your legs.

How to stop restless legs immediately?

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What is the most effective treatment for restless legs?

Making simple lifestyle changes can help alleviate symptoms of RLS :Try baths and massages. Soaking in a warm bath and massaging the legs can relax the muscles.Apply warm or cool packs. ... Establish good sleep hygiene. ... Exercise. ... Avoid caffeine. ... Consider using a foot wrap or a vibrating pad.

What triggers restless leg syndrome?

Often, there's no known cause for RLS . Researchers suspect the condition may be caused by an imbalance of the brain chemical dopamine, which sends messages to control muscle movement.

How do you get rid of restless leg syndrome permanently?

There's no cure for RLS. But if you have the disorder, lifestyle changes and medication can help improve your quality of life. The goals of RLS treatment are to prevent or relieve symptoms, improve sleep, and correct underlying conditions or habits that trigger or worsen RLS symptoms.

What is the most common drug used for restless leg syndrome?

The drugs that are used first to treat restless legs syndrome most often include ropinirole, pramipexole, and rotigotine. The drug gabapentin enacarbil is also used, but usually only when the other drugs don't provide relief.

What is your body lacking when you have restless legs?

The two most common conditions are iron-deficiency anemia (low blood count) and peripheral neuropathy (damage to the nerves of the arms and legs, often caused by underlying conditions such as diabetes).

Why put a bar of soap under your pillow?

2:403:04Put a bar of soap in the bed or under the pillow while sleeping - YouTubeYouTubeStart of suggested clipEnd of suggested clipBe happy to see you in a different.MoreBe happy to see you in a different.

What vitamins help restless leg syndrome?

A 2014 study found that vitamin D supplements reduced RLS symptoms in people with RLS and vitamin D deficiency ( 9 ). And for people on hemodialysis, vitamins C and E supplements may help relieve RLS symptoms (4, 10 ). Supplementation with iron or vitamins D, C, or E can help certain people with RLS.

What is the best muscle relaxer for restless leg syndrome?

Certain medications, such as gabapentin (Neurontin, Gralise), gabapentin enacarbil (Horizant) and pregabalin (Lyrica), work for some people with RLS . Muscle relaxants and sleep medications.

Are there any new treatments for restless leg syndrome?

The FDA has approved gabapentin enacarbil for use in RLS, preferring it over standard gabapentin because it has fewer side effects. Another similar drug, pregabalin17, also shows promising results for RLS symptoms and sleep quality, and carries a low risk of side effects.

Is there an over-the-counter medication for restless leg syndrome?

No natural or over-the-counter (OTC) medications consistently improve RLS. OTC sleeping medicines such as Benadryl (an antihistamine) and melatonin may actually worsen symptoms.

Does Elevating your legs help with restless legs?

By keeping the legs in place, it soothes the nerves in the legs and prevents compression, reducing the chances of RLS occurring by a lot.

How to treat RLS?

2. Healthy sleep habits.

Why is RLS important?

Because of the effects RLS can have on your life, treatment is important. Methods of treatment are varied, as the root cause of RLS isn’t truly known. For instance, some researchers suggest that RLS is caused by problems with the brain chemical dopamine, while others suggest that it’s related to poor circulation.

Does sugar affect RLS?

Some people claim that eating lots of sugar or wearing tight clothing aggravates their RLS symptoms. While there’s not a lot of research to back up these connections, you might want to use some trial and error to see what seems to affect your own symptoms.

What are the health conditions that are linked to RLS?

Certain health conditions have been found to be related to RLS. End-stage renal (kidney) disease, or ESRD, and nerve damage from diabetes have been linked with RLS. Iron deficiency anemia also has a strong connection with RLS (see iron below) ( 4, 5#N#Trusted Source#N#, 6#N#Trusted Source#N#).

What is the first step in addressing RLS?

Your first step in addressing RLS should be to figure out if something is causing it. While RLS can be related to things that are largely out of your control, such as genetics or pregnancy, other possible factors can be addressed.

Can RLS cause anxiety?

As a result of these problems, RLS can lead to anxiety and depression.

Can RLS cause kidney failure?

Some people have primary RLS, which has no known cause. Others have seconda ry RLS, which is typically associated with nerve problems, pregnancy, iron deficiency, or chronic kidney failure. For most people with RLS, symptoms are mild. But if your symptoms are moderate to severe, RLS can have a big impact on your life.

How to cure restless legs syndrome?

Avoiding tobacco and eating a healthy diet: The Restless Legs Syndrome Foundation 10 recommends reducing alcohol, caffeine, sugar, and salt and following a healthy diet rich in vitamins and minerals. In addition to relieving RLS symptoms, a healthy diet can help improve sleep quality. Exercising: Moderate exercise and stretching may help reduce RLS ...

What is the best medication for restless legs?

Restless Legs Syndrome Medication. Medication 16 is currently considered the gold standard for people with moderate to severe RLS. To reduce the risk of unpleasant side effects, always work with a doctor to find the medication that’s right for you.

What is the best way to relieve RLS?

Some physicians also recommend using a pneumatic compression device to ease RLS symptoms. It’s thought that compression of the veins helps boost circulation and reduce the uncomfortable sensations caused by RLS.

Can you get relief from RLS after massaging?

Receiving massages or self-massaging: Some people find relief from RLS symptoms after massaging affected areas.

What vitamins are good for RLS?

Other vitamins and minerals such as magnesium 5, zinc 6, and vitamin D 7 may also play a role in RLS. Pregnant women in particular may benefit from folate supplements 8, while people with kidney problems may benefit from vitamin C and E supplements 9.

Can iron supplements help with RLS?

Many cases of RLS are associated with iron deficiency 4, which can be treated with iron supplements. These have few side effects apart from stomach complaints and constipation, and they work to reduce symptoms of RLS in many people with low iron and ferritin levels or iron-deficiency anemia.

What causes RLS to be reduced?

Peripheral neuropathy. Renal insufficiency. Medication such as antihistamines and certain antidepressants. For many people, addressing these factors may lead to a drastic reduction in RLS symptoms. However, if symptoms are still bothersome, or if they interfere with sleep, doctors may advise additional remedies.

What is the best drug for RLS?

BRAs such as zolpidem (Ambien®), eszopiclone (Lunesta®), and zaliplon (Sonata®) are shorter acting agents than clonazepam and may be equally effective. BRAs are most effective in those with mild symptoms.

Is there a cure for restless legs?

Unfortunately, there is no known cure for restless legs syndrome. At present, there is no one drug which works for everybody, but most individuals with restless legs syndrome will find some benefit and relief with the currently available medications for treating this disorder, which can be divided into several categories: dopamine-related medications, opiates, benzodiazepines receptor agonists (BRAs), alpha-2 delta medications and iron supplementation.

Is RLS a precursor to Parkinson's disease?

The dopamine-related drugs include levodopa, pramipexole, ropinirole and rotigotine. These drugs are also used for Parkinson's disease. However, there is no indication that RLS is related to, or is a precursor of, Parkinson's disease. These medications are likely to be effective in reducing symptoms in 90 percent of patients with restless legs ...

Is RLS pain a problem?

It is important to realize that RLS for a majority of patients is not about pain; it is an abnormal, uncomfortable sensation. Tolerance to the opiates when treating RLS seems to be less of a problem than that seen with treatment of chronic pain disorders.

1. Try a Warm Bath Before Bed

For instant relief from restless legs at night, Dr. Matta suggests finding a bedtime routine that primes your body to relax before RLS can kick in. She especially recommends taking a warm bath to help you wind down.

3. Skip Caffeine, Tobacco and Alcohol

Using these substances can cause RLS symptoms to flare up for some people, according to the American Academy of Family Physicians. Try cutting them out of your day to see if they improve your symptoms.

4. Consider Certain Diet Changes

If you have restless legs, try eating more foods rich in magnesium, like pumpkin seeds.

5. Reduce Your Stress

Oh, look — it's our old friend, stress. You're probably sick of hearing about how stress affects pretty much every health condition known to humankind, but it's the truth.

6. Use a Weighted Blanket

While there isn't any clinical data on using weighted blankets for restless legs syndrome, Dr. Matta says they can be a helpful at-home remedy for a few different reasons:

8. Ask About Iron Supplements

As John Hopkins Medicine explains, another theory about RLS is that it's linked to low levels of iron. Thus, taking a daily iron supplement might help relieve symptoms. (It's important to note, though, that if your RLS isn't caused by low iron, then taking an iron supplement won't help.

9. Consider Medications

The right medication for RLS depends on what may be causing the condition.

How to treat restless legs?

How is restless legs syndrome (RLS) treated? Treatment for RLS is based on the type of symptoms you have and how bad they are. Getting regular exercise and enough sleep may be enough for mild symptoms. But if your symptoms get in the way of how well you can function, you may need medicines.

What to do if you have RLS while pregnant?

For example, you'll take iron supplements if you aren't getting enough iron. If RLS starts during pregnancy, your doctor may just recommend exercise and stretching. For children, regular exercise and sleep ...

What to do if you have restless legs?

Talk with your doctor about your options to relieve the symptoms of your restless legs syndrome. Only your doctor knows your medical history and can help guide you to a drug that’s right for you. Last medically reviewed on September 4, 2019.

How do drugs help with restless legs?

Certain drugs can help treat the symptoms of restless legs syndrome by acting like the chemicals in this pathway or by helping these chemicals function normally.

Can restless legs be treated?

You have several drug options to treat your restless legs syndrome. However, these medications affect each person differently. It may be necessary to change medications several times before you find the one that works for you.

Does Gaba work for restless legs?

GABA doesn’t work normally in people with restless legs syndrome. The structure of the drug gabapentin enacarbil is very similar to GABA. However, the exact way that gabapentin enacarbil improves restless legs syndrome isn’t known. Gabapentin enacarbil is a newer drug that’s been studied less than the dopamine agonists.

Can dopamine agonists help with restless legs?

These drugs may help dopamine work better to control the symptoms of restless legs syndrome. Dopamine agonists should be used for short-term treatment. Long-term use of these drugs may lead to symptoms that are more severe. These symptoms may last longer and happen in locations other than your legs.

What is the class of drugs that treat restless legs?

A drug class is a group of drugs that act in a similar way. Dopamine agonists are often the first drugs used as treatment for restless legs syndrome.

Can restless legs cause involuntary movement?

It’s believed that people with restless legs syndrome have changes in the normal function of these chemicals. These changes may cause the involuntary movement that’s typical of restless legs syndrome. Certain drugs can help treat the symptoms of restless legs syndrome by acting like the chemicals in this pathway or by helping these chemicals ...

What is the RLS Foundation?

By assessing the findings, RLS Foundation is able to develop new tools to support patients, partners/spouses and physicians as they work together to achieve long-term disease management. The survey findings provide insight that helps the Foundation educate the medical community and the general public about RLS.

How to help a person with a symtom?

Identify and track any habits or activities that worsen your symptoms. Review your diet to ensure it is healthy and balanced. Eliminate or limit alcohol and caffeine from your diet to help improve sleep. Find activities that help you cope.

Is there a cure for RLS?

There is currently no cure for RLS, but many treatment options are available to help manage symptoms. Your doctor can help you explore ways to lessen your symptoms through lifestyle changes, self-care and medication. If you need medication, your healthcare provider will guide you through careful trials to find a drug and dosage ...

What is the cause of RLS?

A lack of dopamine (a type of chemical transmitter in the body) or low iron is thought to play a role, and the syndrome is also strongly associated with depression or anxiety disorders. RLS may be the only complaint a person has, or it may seem to follow on from another disorder.

How to tell if you have RLS?

There is no specific exam or lab test a doctor can do to determine if you have RLS. Your description of what happens to your body when you try to relax is usually sufficient. Tell your doctor if you have: 1 An overwhelming urge to move your limbs, accompanied by an uncomfortable or tingling sensation 2 Funny sensations in your legs triggered by rest, relaxation, or sleep, and relieved with movement 3 Symptoms that are worse at night and better in the morning.

What medications can you take to treat a swollen ear?

Taking certain medicines, such as antinausea pills (antiemetics), antipsychotics, antidepressants, and some antihistamines.

Is RLS worse for women or men?

Both legs are usually affected although one may be worse than the other. In more severe cases, the arms and lower trunk may also be affected. RLS affects more than twice as many women as men. Four out of five people with RLS have PLMS (Periodic Limb Movement of Sleep) as well.

What is the term for a nerve that causes a person to feel a throbbing sensation in their legs

Restless legs syndrome (RLS) is a nerve disorder characterized by throbbing, pulling, creeping or other unpleasant sensations in the legs and an uncontrollable, usually overwhelming, urge to move them.

Can a doctor test for RLS?

There is no specific exam or lab test a doctor can do to determine if you have RLS. Your description of what happens to your body when you try to relax is usually sufficient. Tell your doctor if you have:

How to relieve restless legs?

Weighted blankets. Use a weighted blanket to relieve symptoms of restless legs. The light pressure can bring your focus to the feeling of weight from the blanket, rather than on the tingling sensation. [12] Weighted blankets can also provide a sense of comfort that reduced anxiety, which has been correlated with RLS. [13]

How to help with RLS?

Exercise. Research shows that people with RLS who exercise experience fewer symptoms. [14] One study showed that women who practiced yoga saw fewer symptoms, reduced stress levels, and better moods. [15] It doesn’t have to be a full triathlon—even taking a short walk each day can make an impact in treating RLS.

How does RLS affect sleep?

RLS disrupts sleep and interferes with patients getting the rest and recuperation that their bodies need. Patients often experience sleep deprivation, insomnia, excessive daytime sleepiness, and exhaustion. [4] These harmful patterns can interrupt your daily routine, get in the way of your work or school productivity, and affect your relationships with your partner or loved ones. Over time, sleep deprivation can cause long-term health issues like high blood pressure, diabetes, heart attack, or even stroke. [5]

Is RLS passed down genetically?

Around 40% of RLS patients [2] have a family history of the disorder, making it likely that the disorder is passed down genetically. [3] RLS has also been associated with a variety of other illnesses, like Parkinson’s, fibromyalgia, multiple sclerosis, and chronic renal disease. Some medications for psychiatric conditions or gastrointestinal diseases can also make RLS symptoms worse.

Can you get relief from restless leg syndrome?

Although living with Restless Leg Syndrome can be frustrating, tiring, and painful, these at-home remedies can often provide much-needed relief. If home remedies fail to alleviate your symptoms, it’s best to contact your healthcare provider, as you may need blood tests or prescription drugs to treat the disorder. While there’ s no one-size-fits-all solution , many of my patients have found successful strategies for coping with RLS that allow them to get back to enjoying a healthy, joy-filled life with loved ones.

How to get rid of RLS?

Massage. Try massaging your legs or having a partner massage them for you. [10] If it helps you relax, you can also take a bath and lightly massage your legs. Research has shown that massage can help manage the symptoms of RLS, potentially due to the dopamine released and improved circulation. [11]

Can iron deficiency cause restless legs?

Iron supplements. Studies have shown that iron deficiency may be linked to Restless Leg Syndrome. [6] Making sure to get enough iron may help reduce symptoms of RLS. [7]

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Treatment

Mechanism of action

Uses

Prognosis

Medically reviewed by
Dr. Govind Desai
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves managing the underlying conditions.
Medication

Iron Replacement: Iron replacement is suggested whose fasting serum ferritin levels are < 75 micrograms/litre. Usually recommended when the condition is secondary to iron deficiency anemia.

Ferrous sulphate . Ferric carboxymaltose


Antidepressants: To reduce the symptoms of depression, which may result to disturbed sleep pattern.

Buproprion . Ropinirole . Rotigotine . Pramipexole


Calcium channel regulators: Work for some chronic, persistent cases. Usually recommended in some cases.

Gabapentin . Pregabalin


Narcotic medication: Usually addictive and are used if other drugs do not work. Usually recommended in some cases.

Oxycodone . Hydrocodone


Sedatives: To help sleep better.

Clonazepam . Eszopiclone . Temazepam

Self-care

Always talk to your provider before starting anything.

  • Avoid caffine
  • Leg stretching exercises
  • For symptommatic relief : Walking , bicycling, soaking the affected limbs and Leg massage are recommended

Nutrition

Foods to eat:

  • Iron rich foods such as spinach
  • Vitamin A containing foods such as carrots
  • Protein rich foods such as eggs, milk
  • Zinc-rich foods like green peas, eggs, wheat germ, and chickpeas

Foods to avoid:

  • NA

Specialist to consult

Neurologist
Specializes in treating diseases of the nervous system, which includes the brain, the spinal cord, and the nerves.
Somnologist
Specializes in the diagnosis and therapy of sleep disturbances and disorders.

Pharmacology

  • Unfortunately, there is no known cure for restless legs syndrome. At present, there is no one drug which works for everybody, but most individuals with restless legs syndrome will find some benefit and relief with the currently available medications for treating this disorder, which can be divided into several categories: dopamine-related medicatio...
See more on hopkinsmedicine.org

Interactions

  • Dopamine is a chemical that is produced by certain cells in the brain and this group of drugs functions to either increase the amount of dopamine made by the cell (levodopa) or increase the dopamine signal to other surrounding cells by mimicking dopamine in the brain. The dopamine-related drugs include levodopa, pramipexole, ropinirole and rotigotine.
See more on hopkinsmedicine.org

Significance

  • These drugs are also used for Parkinson's disease. However, there is no indication that RLS is related to, or is a precursor of, Parkinson's disease. These medications are likely to be effective in reducing symptoms in 90 percent of patients with restless legs syndrome. Excessive sleepiness, increased compulsive behavior and more commonly, augmentation, a paradoxical worsening of …
See more on hopkinsmedicine.org

Benefits

  • An estimated 85 percent to 90 percent of patients with RLS will respond very well to opiates. An analysis of drug responses in RLS over a 2 -10 year period showed that 85 percent of RLS patients who started on methadone were still on it compared to less than 20 percent of those started on a dopamine drug. The median starting dose for methadone in this study was 10 mg per day with …
See more on hopkinsmedicine.org

Administration

  • This group of drugs is also known as sleeping pills and has valium-like effects. The structure of the parent compound was designated as a benzodiazepine, and later research identified a benzodiazepine receptor. This receptor interacts with a larger GABA receptor.
See more on hopkinsmedicine.org

Research

  • These drugs interact with one of the calcium channel proteins, alpha-2 delta protein. Calcium channels allow the charged calcium ion to move into the nerve cell and are therefore important in activating, deactivating and stabilizing the electrical activity of the nerve cell. The alpha-2 delta drugs are also used to treat patients with nerve-damage related pain even in those without RLS. …
See more on hopkinsmedicine.org

Effects

  • The significance of low iron in causing RLS is outlined in the segment on Causes of Restless Legs Syndrome.
See more on hopkinsmedicine.org

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