Treatment FAQ

what to expect from lymphoma treatment

by Taya Effertz Published 2 years ago Updated 1 year ago
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Medication

The goal of treatment is to destroy as many cancer cells as possible and bring the disease into remission. Lymphoma treatments include: Active surveillance. Some forms of lymphoma are very slow growing. You and your doctor may decide to wait to treat your lymphoma when it causes signs and symptoms that interfere with your daily activities.

Procedures

Finishing treatment for lymphoma can bring a range of emotions. Some of these are likely to be positive but others might be harder to cope with. Dealing with challenges can have an impact on how you feel overall and on your self-esteem. Be patient with yourself.

Therapy

In general, treatment is less likely to work each time your lymphoma comes back (relapses). The lymphoma cells can become resistant to treatment. This means that reducing or getting rid of your lymphoma (remission) might not work, or might last only a short time before you relapse again.

Self-care

The lymphoma cells can become resistant to treatment. This means that reducing or getting rid of your lymphoma ( remission) might not work, or might last only a short time before you relapse again. Your doctors carefully consider your specific circumstances and the type of lymphoma you have before they advise whether or not to have more treatment.

Nutrition

What is the goal of treatment for lymphoma?

How does it feel to finish treatment for lymphoma?

What happens when lymphoma relapses?

Can lymphoma go into remission?

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How long does lymphoma treatment usually last?

Treatment is normally given in short daily sessions, Monday to Friday, usually for no more than 3 weeks.

What happens after lymphoma treatment?

The risk of developing cancer is further increased with family history of cancer. Second cancers that develop as a late effect to chemotherapy treatment for lymphoma include the blood cancers myelodysplastic syndromes (MDS) and leukaemia. Other cancers can include lung, bowel, breast and skin cancer.

How successful is treatment for lymphoma?

Overall, treatment for Hodgkin lymphoma is highly effective and most people with the condition are eventually cured.

How many rounds of chemo is normal for lymphoma?

Treatment for many patients is chemotherapy (usually 2 to 4 cycles of the ABVD regimen), followed by radiation to the initial site of the disease (involved site radiation therapy, or ISRT). Another option is chemotherapy alone (usually for 3 to 6 cycles) in selected patients.

Can you live a normal life after lymphoma?

It takes time but most people adjust well to life after a diagnosis of lymphoma and find a 'new normal'. This might involve making some changes to your everyday life.

Can you make a full recovery from lymphoma?

There are very few cancers for which doctors will use the word 'cure' right off the bat, but Hodgkin lymphoma (HL), the most common cancer diagnosis among children and young adults, comes pretty darn close: Ninety percent of patients with stages 1 and 2 go on to survive 5 years or more; even patients with stage 4 have ...

What are some of the most serious concerns for patients undergoing treatment with lymphoma?

Late and Long-term Side Effects of Hodgkin Lymphoma TreatmentSecond cancers. One uncommon but very serious side effect of HL treatment is developing a second type of cancer later on. ... Fertility issues. ... Infections. ... Thyroid problems. ... Heart disease and stroke. ... Lung damage. ... Special concerns in childhood Hodgkin lymphoma survivors.

Is lymphoma a terminal?

Survival for all non-Hodgkin lymphomas Generally, for people with non-Hodgkin lymphoma in England: around 80 out of every 100 people (around 80%) survive their cancer for 1 year or more after they are diagnosed. around 65 out of every 100 people (around 65%) survive their cancer for 5 years or more after diagnosis.

What is the newest treatment for lymphoma?

A drug called ibrutinib (Imbruvica) has been developed to shut down that pathway. It is being used and tested in a number of ways: In the last several years, the drug has been approved for the treatment of small lymphocytic lymphoma and Waldenstrom macroglobulinemia, both indolent non-Hodgkin lymphomas.

How do you feel after first round of chemo?

The most commonly reported side effect after receiving chemotherapy is fatigue. 7 Give yourself time for extra rest and sleep in the days after a session. Tell your healthcare provider if your fatigue begins to affect your ability to function or complete basic tasks, like bathing.

What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia. It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured.

Do you lose your hair with chemo for lymphoma?

Hair loss is quite common in people who are treated with chemotherapy; overall, around 2 in 3 people experience hair loss. Chemotherapy kills lymphoma cells, but it can also destroy healthy cells, particularly those that normally divide quickly. Hair follicles produce hair.

What is the treatment for lymphoma?

CAR T-cell therapy for lymphoma includes axicabtagene ciloleucel ( Yescarta) and tisagenlecleucel (Kymriah ). Before you can get this therapy, you'll need a thorough evaluation to make sure your organs are working well enough to handle it, Persky says.

How long do you have to stay in the hospital for car T cell therapy?

You'll need to stay in the hospital for at least a week so your doctors can watch you closely to see if you have any side effects. Almost everyone who gets CAR T-cell therapy has some mild side effects, Persky says. It’s possible, but less common, to have severe side effects.

How often can you get rituximab?

"Some, like rituximab, can be given once a week for maybe 4 weeks.

How long does it take for a T cell to be removed?

Once your doctor gives you the green light, the next step is for you to get leukapheresis. This procedure removes T cells from your body. It takes a few hours. During that time, you go through a process like giving blood -- except the point is to collect white blood cells, and a second IV returns blood to your body.

Can immunotherapy help lymphoma?

If you and your doctor decide to try immunotherapy for your lymphoma, you know it’s going to use your immune system to target your cancer. But do you know what the treatments will be like and what the side effects may be? It can vary based on the type of immunotherapy that you get.

What kind of doctor treats lymphoma?

This type of doctor specializes in the diagnosis and treatment of cancer. Oncologists in Stanford’s lymphoma Program have years of training and experience in cancer care. The treatments we offer include: 1 Radiation therapy 2 Medical therapy, such as chemotherapy, (medications that travel through the bloodstream to treat cancer anywhere in the body)

What to expect at first appointment for cancer?

During this visit, your doctor will discuss your medical history with you in detail, perform a physical examination, and discuss possible treatment options. During your first visit, we will share some important information about cancer and your treatment options.

How long does non-Hodgkin lymphoma last?

Although “indolent” or slow growing forms of non-Hodgkin lymphoma are not currently curable, the prognosis is still very good. Patients may live for 20 years or more following an initial diagnosis. In certain patients with an indolent form of the disease, treatment may not be necessary until there are signs of progression.

What is the treatment for non-Hodgkin lymphoma?

Many people treated for non-Hodgkin lymphoma will receive some form of chemotherapy, radiation therapy, biologic therapy, immunotherapy, or a combination of these. Bone marrow, stem cell transplantation, or CAR T-cell therapy may sometimes be used.

Is lymphoma a heterogeneous disease?

Blood cancers, including lymphoma, are extremely heterogeneous, and can involve a variety of treatment options, often in combination. Some form of chemotherapy, radiation therapy, immunotherapy, or a combination is typically used to treat Hodgkin lymphoma. Bone marrow or stem cell transplantation may also sometimes be done under special ...

How to treat lymphoma after treatment?

Treatment for HL should remove all traces of the lymphoma. After treatment, the doctor will do tests such as PET/CT scans to look for any signs of HL. If HL is still there, most experts think that more of the same treatment is unlikely to cure it.

What to do if you have HL?

If HL is still there after these treatments, most doctors would recommend high-dose chemo (and possibly radiation) followed by an autologous stem cell transplant, if it can be done. If cancer still remains after this, an allogeneic stem cell transplant may be an option.

What is the best treatment for stem cell transplant?

For those who don’t respond to treatment, chemo using different drugs or high-dose chemo (and possibly radiation) followed by a stem cell transplant may be recommended. Treatment with an immunotherapy drug such as brentuximab vedotin (Adcetris), nivolumab (Opdivo), or pembrolizumab (Keytruda) might be another option.

How many cycles of chemo for ABVD?

Treatment is generally more intense than that for favorable disease. It typically starts with chemotherapy (usually with the ABVD regimen for 4 to 6 cycles or other regimens such as 3 cycles of Stanford V). PET/CT scans are often done after several cycles of chemo to see if (and how much) more treatment is needed.

Why do you need a PET scan after chemo?

If a person can’t have chemotherapy because of other health issues , radiation therapy alone may be an option.

Can radiation cure lymphoma?

This holds true no matter how long ago the radiation was first given. If the lymphoma returns after many years, using the same or different chemo drugs (possibly along with radiation) might still cure it. On the other hand, HL that recurs soon after treatment may need more intensive treatment.

Can HL recur after treatment?

On the other hand, HL that recurs soon after treatment may need more intensive treatment . For example, if the HL has returned within a few months of the original treatment, high-dose chemo (and possibly radiation) followed by an autologous stem cell transplant may be recommended.

How to cope with lymphoma after treatment?

Adjusting to life after treatment for lymphoma. Finishing treatment for lymphoma can bring a range of emotions. Some of these are likely to be positive but others might be harder to cope with. Dealing with challenges can have an impact on how you feel overall and on your self-esteem. Be patient with yourself.

What does it feel like to be alone after lymphoma treatment?

You might have a sense of facing the unknown and a general feeling of uncertainty. Some people describe feeling ‘lost’ or alone after treatment. After getting used to regular hospital appointments, you might feel unsettled or anxious without so much contact with your medical team. You might feel unsure about what to expect in the future. Some people worry about the possibility that their lymphoma will come back (relapse) or get worse.

What is the term for a disease that can develop months or even years after treatment?

Late effects are health conditions that can develop months or even years after treatment for lymphoma. Modern treatments are designed to treat lymphoma effectively while keeping the risk to your long-term health as low as possible. Your doctor will monitor you for late effects at your follow-up appointments.

What happens after cancer treatment?

After treatment, patients will move to a follow-up pathway that suits their needs, and ensures they can get rapid access to clinical support where they are worried that their cancer may have recurred. NHS England long-term plan.

Can you connect with someone who has lymphoma?

Each person’s experience with lymphoma is unique, but connecting with other people who have been treated for lymphoma can be a helpful source of support. You could be in touch with someone who might be able to relate to your experience through out peer-support buddy service or closed Facebook support group.

Can cancer cause side effects?

Side effects. For some people, side effects can go on during recovery, which might feel disheartening when you have finished your treatment. Changes in weight are fairly common after treatment for cancer. This can be for a number of reasons, including the effects of the cancer itself, changes in diet and changes in physical activity levels ...

Can lymphoma cause bleeding?

Low blood counts can increase your risk of developing infections, and can make you bruise or bleed more easily (for example, with nosebleeds, bleeding gums or heavier periods) than before you had treatment. While your blood counts are building back up, take steps to lower your risk of infection and bleeding.

How does lymphoma affect the liver?

Normally, your liver and kidneys cope with excess levels of chemicals by removing waste products. If lymphoma stops these organs from functioning as they should, it can lead to an imbalance of chemicals. High levels of chemicals in the bloodstream often lead to a lower level of consciousness.

What happens when lymphatic tissue presses on organs?

As the tissue presses on parts inside your body, it puts pressure on them and can cause blockages and pain.

What happens to your body at the end of your life?

Gradually, your body slows down and stops functioning as it should.

What happens if you get sepsis?

If the infection gets into your bloodstream ( sepsis ), you could lose consciousness. A shortage of oxygen to your organs: a shortage of red blood cells ( anaemia) can stop your organs from getting enough oxygen to function properly. This can cause shortness of breath, weakness and fatigue.

Is palliative care considered lymphoma?

This is known as ‘ palliative care ’ and is separate to active treatment given to treat your lymphoma. There are many factors to think about when deciding whether or not to continue with active treatment. Your medical team considers lymphoma-specific factors, such as: the type of lymphoma you have and its stage.

Can lymphoma cause breathing problems?

If lymphoma affects your lungs, you are likely to have difficulties breathing. You also have an increased risk of getting a chest infection, which can be difficult for your immune system to deal with.

Does lymphoma come back?

In general, treatment is less likely to work each time your lymphoma comes back ( relapses ). The lymphoma cells can become resistant to treatment. This means that reducing or getting rid of your lymphoma ( remission) might not work, or might last only a short time before you relapse again.

What is the treatment regimen for lymphoma?

Many patients who are treated for lymphoma are given combination chemotherapy, which means two or more drugs, instead of single-agent therapy. These chemotherapy drugs are given in a specific order (schedule) during certain days of each treatment cycle—this is called a treatment regimen.

What are the benefits of chemotherapy?

An advantage of chemotherapy is that it can also travel throughout the bloodstream to kill the cancer cells wherever they may be located. Many patients who are treated for lymphoma are given combination chemotherapy, ...

What is the purpose of chemo?

The purpose of chemotherapy is to kill cancer cells. It is usually used to treat cancer when it is systemic, meaning that the cancer has spread throughout the body. Lymphoma is caused by uncontrolled growth in one or the other of two types of white blood cells called T cells and B cells.

How often do you take chemo?

During chemotherapy, patients receive the drug or drugs orally (pill taken by mouth) or intravenously (IV; injection directly into the vein), one or more times a week for one or more weeks, followed by a rest period.

Does chemotherapy kill cancer cells?

Chemotherapy halts cell growth and division to prevent cancer cells from making more and more cancer cells; however, chemotherapy drugs not only affect the cancer cells, but also any normal rapidly dividing cells, which can cause side effects. The purpose of chemotherapy is to kill cancer cells. It is usually used to treat cancer ...

What is Stage IV lymphoma?

Stage IV lymphoma is the most advanced, but this can mean very different things for different people -- including living a fulfilling life for many years, in some cases. If the disease does progress toward the end of life, people go through stages that include changing the focus of therapy, emphasis on quality of life and symptom control, ...

How many different types of lymphoma are there?

There are more than 70 different kinds of lymphoma, a cancer of the immune cells 1. As such, the path from diagnosis to the end of life can vary quite a bit. Hodgkin lymphoma is very curable, while some non-Hodgkin lymphomas are more difficult to treat 4 8. Stage IV lymphoma is the most advanced, but this can mean very different things ...

Does radiation help lymphoma?

For example, if lymphoma spreads to the bones, radiation may be used to relieve pain. Chemotherapy may be advantageous in shrinking distant tumors that are blocking the function of organs, such as the bowels.

Does chemotherapy help lymphoma?

As lymphoma spreads throughout the body, therapies that were previously used to treat the cancer may be used as a means of controlling symptoms 1. Chemotherapy may be advantageous in shrinking distant tumors that are blocking the function of organs, such as the bowels.

How to treat lymphedema?

Treatment focuses on reducing the swelling and controlling the pain. Lymphedema treatments include: Exercises. Light exercises in which you move your affected limb may encourage lymph fluid drainage and help prepare you for everyday tasks, such as carrying groceries.

What tests can be done to check lymphedema?

If the cause of your lymphedema isn't as obvious, your doctor may order imaging tests to get a look at your lymph system. Tests may include: MRI scan. Using a magnetic field and radio waves, an MRI produces 3-D, high-resolution images. CT scan.

How to help lymphedema in arm?

A certified lymphedema therapist can teach you exercises that may help. Wrapping your arm or leg. Bandaging your entire limb encourages lymph fluid to flow back toward the trunk of your body.

How to find obstructions in lymphatic system?

Ultrasound can help find obstructions. Radionuclide imaging of your lymphatic system (lymphoscintigraphy). During this test you're injected with a radioactive dye and then scanned by a machine. The resulting images show the dye moving through your lymph vessels, highlighting blockages.

How to get lymph fluid out of arm?

Long sleeves or stockings made to compress your arm or leg encourage the flow of the lymph fluid out of your affected limb. Wear a compression garment when exercising the affected limb. Obtain a correct fit for your compression garment by getting professional help.

What can CT scans reveal?

CT scans can reveal blockages in the lymphatic system. Doppler ultrasound. This variation of the conventional ultrasound looks at blood flow and pressure by bouncing high-frequency sound waves (ultrasound) off red blood cells. Ultrasound can help find obstructions.

Can massage help cancer?

And various massage treatments may benefit people with active cancer. Be sure to work with someone specially trained in these techniques. Massage isn't for everyone. Avoid massage if you have a skin infection, blood clots or active disease in the involved lymph drainage areas. Pneumatic compression.

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Diagnosis

Clinical Trials

Alternative Medicine

Coping and Support

Medically reviewed by
Dr. Rakshith Bharadwaj
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatments include medications, radiation therapy, and bone marrow transplant.
Medication

Chemotherapy: Drugs to kill cancer cells, either as pill or injected directly into the bloodstream through the veins (intravenous).

Methotrexate


Targeted drug therapy: Drugs that target a particular substance on the cancer cells are used to destroy them.

Bortezomib


Immunotherapy: Work by targeting various proteins on tumor cells.

Nivolumab

Procedures

Bone marrow transplantation: Also known as stem cell transplant, the therapy involves introducing healthy bone marrow stem cells from a donor.

Therapy

Radiation therapy:Uses powerful rays to kill cancer cells.

Self-care

Always talk to your provider before starting anything.

  • Get adequate rest
  • Eat a healthy and nutritious diet

Nutrition

Foods to eat:

  • NA

Foods to avoid:

  • NA

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Hematologist
Specializes in the study of the blood and blood disorders.

Preparing For Your Appointment

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Tests and procedures used to diagnose lymphoma include: 1. Physical exam.Your doctor checks for swollen lymph nodes, including in your neck, underarm and groin, as well as a swollen spleen or liver. 2. Removing a lymph node for testing.Your doctor may recommend a lymph node biopsy procedure to remove all or part of a …
See more on mayoclinic.org

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