Treatment FAQ

what the treatment for narcolepsy

by Prof. Romaine Rath Published 2 years ago Updated 2 years ago
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Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day. Doctors often try modafinil (Provigil) or armodafinil (Nuvigil) first for narcolepsy.Nov 6, 2020

Medication

Treating narcolepsy without medication

  • cultivating a habit for keeping a regular sleep schedule
  • taking scheduled long day time naps or timed short naps
  • developing habit for taking short 20-minutes naps across different parts of a day
  • handle a sleep attack with preparedness by scheduling meetings, work
  • regular exercise
  • avoiding alcohol. ...
  • nutritious diet

More items...

Nutrition

There is no cure for narcolepsy, but medications and lifestyle modifications can help you manage the symptoms. Medications for narcolepsy include: Stimulants. Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day.

What is the best natural treatment for narcolepsy?

What to Eat

  • Follow a heart-healthy diet. Narcolepsy increases your risk of stroke, heart attack, and heart failure. ...
  • Try a low-carb diet. When you eat a big, high-carb meal, your body makes less of the hormone ghrelin, which stimulates wakefulness.
  • Consider a keto diet. ...
  • Try caffeine. ...
  • Avoid alcohol. ...

Will there ever be a cure for narcolepsy?

There's no specific cure for narcolepsy, but you can manage the symptoms and minimise their impact on your daily life. Making some simple changes to your sleeping habits can sometimes help. If your symptoms are more severe, you'll usually need to take medicine.

What is a good diet for someone with narcolepsy?

Can you cure narcolepsy?

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How can I get rid of narcolepsy naturally?

Natural Ways to Stay Awake With Narcolepsy1 / 11. Stay Awake Naturally. The world narcolepsy was coined in 1880s to mean “seized by somnolence,” or sleepiness. ... 2 / 11. Schedule Naps. ... 3 / 11. Rest Best at Night. ... 4 / 11. Eat Your Way Awake. ... 5 / 11. Watch Your Carbs. ... 6 / 11. Move. ... 7 / 11. Seek Sunshine. ... 8 / 11. Keep Cool.More items...•

What are the 5 signs of narcolepsy?

There are 5 main symptoms of narcolepsy, referred to by the acronym CHESS (Cataplexy, Hallucinations, Excessive daytime sleepiness, Sleep paralysis, Sleep disruption). While all patients with narcolepsy experience excessive daytime sleepiness, they may not experience all 5 symptoms.

What is the main cause of narcolepsy?

What causes narcolepsy. Narcolepsy is often caused by a lack of the brain chemical hypocretin (also known as orexin), which regulates wakefulness. The lack of hypocretin is thought to be caused by the immune system mistakenly attacking the cells that produce it or the receptors that allow it to work.

Can narcolepsy disorder be cured?

Contents. There's no specific cure for narcolepsy, but you can manage the symptoms and minimise their impact on your daily life. Making some simple changes to your sleeping habits can sometimes help. If your symptoms are more severe, you'll usually need to take medicine.

What are the warning signs of narcolepsy?

SymptomsExcessive daytime sleepiness. People with narcolepsy fall asleep without warning, anywhere, anytime. ... Sudden loss of muscle tone. ... Sleep paralysis. ... Changes in rapid eye movement (REM) sleep. ... Hallucinations.

How do doctors test for narcolepsy?

The diagnosis of narcolepsy is usually supported by test results from a polysomnogram and the Multiple Sleep Latency Test (MSLT). A polysomnogram helps your physician assess brain activity during sleep, in particular, how frequently and when REM activity is occurring.

Is narcolepsy a mental illness?

However, narcolepsy is frequently misdiagnosed initially as a psychiatric condition, contributing to the protracted time to accurate diagnosis and treatment. Narcolepsy is a disabling neurodegenerative condition that carries a high risk for development of social and occupational dysfunction.

Does Covid affect narcolepsy?

In concluding, the authors wrote that the greatest takeaway of this review for sleep medicine clinicians and researchers is to consider COVID-19 infection as a possible triggering event leading to narcolepsy.

Does narcolepsy affect memory?

Narcolepsy can present challenges to daily living: in addition to sleepiness, people with narcolepsy may experience mental fogginess, poor memory, and hallucinations.

What foods help narcolepsy?

Research is limited, but some people with narcolepsy say their symptoms improve when they follow a ketogenic (or keto) diet, which is a restrictive, low-carbohydrate, high-fat, moderate-protein diet. “There's some clinical data from small studies of low-carbohydrate, ketogenic diet in people with narcolepsy,” Li says.

Does narcolepsy worsen with age?

Narcolepsy is a lifelong problem, but it does not usually worsen as the person ages. Symptoms can partially improve over time, but they will never disappear completely. The most typical symptoms are excessive daytime sleepiness, cataplexy, sleep paralysis, and hallucinations.

Does caffeine help narcolepsy?

Conclusion: Our findings suggest that a small dose of caffeine has positive effects on alertness in patients with narcolepsy.

How to treat narcolepsy?

Treatment for narcolepsy can be broken down into two categories: 1 Behavioral approaches employ changes in lifestyle and daily habits to manage symptoms and reduce the likelihood of other physical and emotional challenges that often affect people with narcolepsy. 2 Medications can be prescribed to address symptoms. The use of medications is known as pharmacotherapy.

How many medications do you need to treat narcolepsy?

To treat narcolepsy, doctors usually start with one drug to see how well it works for a specific patient. The dosage or timing of doses may be changed as needed, or the doctor may recommend switching medications if the first is not working or well-tolerated.

What is the name of the disorder where you fall asleep involuntarily?

Narcolepsy is a disorder in which the sleep-wake cycle is significantly altered 1. Its central symptom is excessive daytime sleepiness (EDS), which may involve falling asleep involuntarily, even while eating or driving. People with narcolepsy face safety risks including a three- to four-fold increase 2 in their chances of being in an automobile ...

How to sleep better with narcolepsy?

Practical tips to improve sleep routines for people with narcolepsy include: Keep a consistent bedtime and wake time: A stable sleep schedule can ensure that enough time is budgeted for rest and helps habituate the body to sleeping at set times, including at night.

Why is it important to eat healthy when you have narcolepsy?

Eating a healthy diet is important for everyone, but it takes on added importance for people with narcolepsy because they have an elevated risk of obesity. The timing of meals is important as well. Eating too late at night may interfere with normal digestion and is associated with sleep disruptions 8.

What is the symptom of narcolepsy?

There are two types of narcolepsy 3. Narcolepsy type 1 (NT1) frequently involves a symptom called cataplexy, which is a sudden and brief loss of muscle tone in which the individual is conscious. It is triggered by strong emotions, usually positive ones like laughter.

What is behavioral approach in narcolepsy?

Behavioral approaches employ changes in lifestyle and daily habits to manage symptoms and reduce the likelihood of other physical and emotional challenges that often affect people with narcolepsy. Medications can be prescribed to address symptoms. The use of medications is known as pharmacotherapy.

What are the best medications for narcolepsy?

Drugs that act as stimulants and/or reduce the other symptoms of narcolepsy are standard treatments for the condition. They include: Armodafinil ( Nuvigil ): This drug is similar to Provigil. It is also used to reduce excessive daytime sleepiness. Headache and nausea are the most common side effects. Methylphenidate Hcl ( Daytrana, Ritalin ...

How to help narcolepsy stay awake?

It has proven effective in helping patients stay awake for longer periods of time. Home Remedies for Narcolepsy. There are several things you can do at home to help improve the symptoms of narcolepsy and include the following: Maintain a regular sleep schedule.

Can narcolepsy be taken one day a week?

Therefore, some doctors advise people with narcolepsy to abstain from taking it one day each week (typically on a weekend).

Does Pitolisant work on histamine receptors?

It acts on the histamine receptors and mimics histamine. Pitolisant uses the histamine receptors to prompt your brain to stay awake. Solriamfetol ( Sunosi ): This dual-acting dopamine and norepinephrinere uptake inhibitor is also used to treat narcolepsy.

What is the best treatment for narcolepsy?

Central nervous system stimulants are the main treatments used for excessive daytime sleepiness in narcolepsy, and these stimulants include Amphetamine, Methylphenidate, Modafinil, Dextroamphetamine and Armodafinil.

Is it hard to control narcolepsy?

It’s extremely difficult to fully control the symptoms of narcolepsy, and medication adjustments are often necessary . Lifestyle changes are also very important for people suffering from narcolepsy, with oral medications being the mainstay of treatment.

Is narcolepsy a depression?

As mentioned previously, narcolepsy can be confused with depression, and it’s true that there is a link between these two disorders. The co-occurrence of depression in narcolepsy patients has produced mixed results, though, with different studies producing numbers anywhere between 6% and 50%. Author. Recent Posts.

Can narcolepsy be cured?

Although people suffering from narcolepsy can’t be cured, they can be helped. Treatment for this disorder is tailored to each individual and is based on the person’s symptoms and therapeutic response. It could well take months, or even longer, to achieve effective control of symptoms.

Is narcolepsy a neurological disorder?

Narcolepsy can be described as a neurological condition involving a person’s reduced ability to manage the sleep-wake cycle. Although people suffering from narcolepsy can’t be ...

Is narcolepsy more common than fibrosis?

In fact, narcolepsy is as prevalent as Multiple Sclerosis and Parkinson’s disease, and more common than Cystic Fibrosis, but unfortunately it’s just not as well known. The reason for this is that narcolepsy can often be confused with epilepsy, depression, or the side-effect of medications.

Can narcolepsy run in families?

The symptoms of narcolepsy are generally first noticed in young adults or teenagers, but narcolepsy can occur in both women and men at any age. In fact, there’s strong evidence that narcolepsy could run in families, because approximately 10% of people diagnosed with narcolepsy with cataplexy already have a close family member with this neurological disorder. As mentioned previously, narcolepsy can be confused with depression, and it’s true that there is a link between these two disorders. The co-occurrence of depression in narcolepsy patients has produced mixed results, though, with different studies producing numbers anywhere between 6% and 50%.

Official Answer

There is no cure for narcolepsy, but medications and lifestyle modifications can help manage symptoms such as excessive daytime sleepiness (EDS). Medications include:

What lifestyle changes help with narcolepsy?

Lifestyle modifications can help manage symptoms of narcolepsy, and can include:

What is narcolepsy type 1?

Narcolepsy type 1 and narcolepsy type 2 are central disorders of hypersomnolence. Narcolepsy type 1 is characterized by excessive daytime sleepiness and cataplexy and is associated with hypocretin-1 deficiency.

Is hypocretin 1 normal in narcolepsy?

On the other hand, in narcolepsy type 2, cerebrospinal fluid hypocretin-1 levels are normal and cataplexy absent. Despite major advances in our understanding of narcolepsy mechanisms, its current management is only symptomatic.

What are the symptoms of narcolepsy?

The symptoms of narcolepsy can have notable effects during both daytime and night time. The most common symptoms include: Excessive daytime sleepiness (EDS): EDS is the cardinal symptom of narcolepsy, affecting all people with the disorder. EDS involves an urge to sleep that can feel irresistible, and it arises most frequently in monotonous ...

What is narcolepsy sleep disorder?

Narcolepsy is a sleep disorder that is often misunderstood. It is characterized by severe and persistent daytime sleepiness that can cause impairments in school, work, and social settings as well as heighten the risk of serious accidents and injuries.

How long does cataplexy last?

Cataplexy normally affects both sides of the body and lasts for a few seconds to a few minutes. Some people with NT1 only have episodes of cataplexy a few times per year, while others can have a dozen or more episodes per day. Although all people with narcolepsy have EDS, less than a quarter have all of these symptoms.

What is the disorder that disrupts sleep-wake processes?

Narcolepsy is a disorder that disrupts sleep-wake processes. Its primary symptom is excessive daytime sleepiness (EDS), which occurs because the brain is unable to properly regulate wakefulness and sleep 1.

How rare is narcolepsy?

Narcolepsy is relatively rare. NT1 affects between 20 and 67 people per 100,000 in the United States. According to a population based study in Olmstead county Minnesota, NT1 is two to three times more common 4 than NT2, which is estimated to affect between 20 to 67 people per 100,000.

How long does narcolepsy go undiagnosed?

Because it is rare and symptoms may be mistakenly attributed to other causes, narcolepsy can go undiagnosed for many years. The diagnostic process starts with a review of symptoms and medical history.

Is narcolepsy a health issue?

The symptoms of narcolepsy can have significant consequences for a patient’s health and wellness. Accidents are a pressing concern as sleep attacks, drowsiness, and cataplexy can be life-threatening when driving or in other environments where safety is critical.

How to get rid of narcolepsy?

Proper diet. Regular exercise. Behavioral therapy. There is no cure for narcolepsy. The U.S. Food and Drug Administration has approved a drug called modafinil for the treatment of excessive daytime sleepiness.

What is the goal of narcolepsy?

Your tolerance for specific medicines, procedures, or therapies. Expectations for the course of the disease. Your opinion or preference. The goal of treatment of narcolepsy is to help you remain as alert as possible during the day.

How long does it take for a narcolepsy test to show REM?

To test for a genetic mutation often found in people who tend to have narcolepsy. Narcolepsy is not definitively diagnosed in most patients until 10 to 15 years after the first symptoms appear.

What is narcolepsy caused by?

What is narcolepsy? Narcolepsy is a chronic neurological disorder caused by the brain's inability to regulate sleep-wake cycles normally. At various times throughout the day, people with narcolepsy experience fleeting urges to sleep.

What is the main characteristic of narcolepsy?

The main characteristic of narcolepsy is excessive and overwhelming daytime sleepiness, even after adequate nighttime sleep: In addition to a complete medical history and physical exam, there are several lab tests to confirm the diagnosis. The goal of treatment of narcolepsy is to help you remain as alert as possible during the day.

Can narcolepsy be cured by taking naps?

Many people with narcolepsy take short, regularly scheduled naps at times when they tend to feel sleepiest. Improving the quality of nighttime sleep can combat excessive daytime sleepiness and help relieve persistent feelings of fatigue.

Can narcolepsy be controlled?

None of the currently available medications enable people with narcolepsy to consistently maintain a fully normal state of alertness. But excessive daytime sleepiness and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment.

Drugs used to treat Narcolepsy

The following list of medications are in some way related to, or used in the treatment of this condition.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Govind Desai
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Medications and lifestyle modifications help to manage the symptoms.
Medication

Stimulants: Drugs that provoke the central nervous system to help individuals to remain wakeful during the day time.

Modafinil . Armodafinil


Serotonin reuptake inhibitors: Suppress REM sleep, to help ease the indications of cataplexy, hallucinations and sleep paralysis.

Fluoxetine


Tricyclic antidepressants: Drugs used to treat depression. Usually recommended in rare cases.

Protriptyline


Central nervous system depressant: It is highly effective for treating cataplexy. Usually recommended in rare cases.

Sodium oxybate

Nutrition

Foods to eat:

  • Consume a healthy balanced diet with fresh fruit and vegetables. Intake of moderate quantities of poly-unsaturated fatty acids may be helpful (soy oil, castor bean oil or sunflower oil).

Foods to avoid:

  • NA

Specialist to consult

Somnologist
Specializes in the diagnosis and therapy of sleep disturbances and disorders.
Pulmonologist
Specializes in diagnosing and treating conditions that affect the respiratory system.

Preparing For Your Appointment

  • Your doctor may make a preliminary diagnosis of narcolepsy based on your excessive daytime sleepiness and sudden loss of muscle tone (cataplexy). After an initial diagnosis, your doctor may refer you to a sleep specialist for further evaluation. Formal diagnosis requires staying overnigh…
See more on mayoclinic.org

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