Treatment FAQ

what procedure is used by anesthesiologists for treatment of postdural puncture headache?

by Billie Koch Published 3 years ago Updated 2 years ago

Nerve block is also known as block, block anesthesia, or condition anesthesia. Although not a type of anesthesia, a procedure used by anesthesiologists for treatment of a postdural puncture headache is a blood patch also known as an epidural blood patch (EBP).

Prophylactic epidural blood patch – Epidural blood patch (EBP) is an effective treatment for PDPH, and may also be performed prophylactically before a headache occurs for patients in whom an epidural catheter is placed after an inadvertent dural puncture.Jul 27, 2021

Full Answer

What is the treatment for postdural puncture headache?

Feb 03, 2017 · A prophylactic epidural blood patch can be performed through the epidural catheter, which is re-sited after inadvertent dural puncture, just before the epidural catheter is removed. Autologous blood injected into the epidural space is thought to seal the dural defect.

How effective is an epidural blood patch after a dural puncture?

Nov 07, 2021 · For this procedure, 10 ml to 30 ml of autologous venous blood is injected by an anesthesiologist into the epidural space at the level of the prior procedure. This is thought to create a "patch" over the dural puncture and decrease CSF …

What is the association between postdural puncture (PDP) headaches and other headaches?

A wide variety of prophylactic and therapeutic measures have been tried. So far, the therapeutic epidural blood patch is the only treatment for which there is enough evidence to recommend its routine use for severe cases of post-dural puncture headache. Larger multicenter trials are needed to back up alternative treatment strategies.

Is postdural headache (mph) correctly used?

Feb 23, 2018 · The mainstay of treatment and the only method borne out in studies to be effective for PDPHA is the epidural blood patch. 20ml has been shown to be the optimal volume of sterile blood injected into the epidural space, stopping sooner if the patient experiences back pain.

How do you treat a Postdural puncture headache?

Conservative measures for the first 24 to 48 h are considered the initial management strategy, because more than 85% of PDPH resolves with conservative treatment [33]. These measures include bed rest, intravenous hydration, caffeine supplementation, and analgesic medication.

Is PDPH serious?

PDPH symptoms can resolve spontaneously within one to two weeks in over two-thirds of patients. In many cases, symptoms are severe and persistent and require intervention.

How long does a dural puncture take to heal?

The headache usually starts within 48 hours of an epidural UDP and if left untreated, resolves spontaneously in about 2-weeks in most women but may last longer in some women. Smaller gauge dural punctures with spinal anesthesia typically resolve in 2-3 days.

How long does Dura take to heal?

The repair site can take four to six weeks to heal completely.

Is Neuraxial a anesthesia?

Neuraxial anesthesia is the administration of medication into the subarachnoid or epidural space to produce anesthesia and analgesia. It can lead to the complete absence of sensory and/or motor function at or below the site of injection.Apr 2, 2020

What is blood patch procedure?

To apply a blood patch, first your doctor takes blood from your arm. Then the blood is injected into the area of your lower back where the leak happened. The blood restores the pressure around your spinal cord. It also helps seal any leak that may still be there.

Why is lumbar puncture done?

A lumbar puncture can help diagnose serious infections, such as meningitis; other disorders of the central nervous system, such as Guillain-Barre syndrome and multiple sclerosis; or cancers of the brain or spinal cord.Aug 14, 2020

How do you handle a dural puncture?

When dural puncture occurs, several management methods are applied by physicians. The anesthesia can be converted to spinal anesthesia with subarachnoid injection via the epidural needle; general anesthesia can be applied or the epidural catheter can be inserted from a different intervertebral area.

What is the most common complication after neuraxial block?

Neuraxial analgesia and anesthesia are widely used in obstetric anesthesia. The most frequent complication after neuraxial blocks is post-dural puncture headache. It can occur after unintentional dural puncture during epidural procedures or after spinal anesthesia. Unintentional dural puncture occur ….

Can a dural puncture cause headaches?

It can occur after unintentional dural puncture during epidural procedures or after spinal anesthesia. Unintentional dural puncture occurs in 0.15-1.5% of labor epidural analgesia and 50-80% of these women develop post-dural puncture headache. The headache is typically orthostatic in nature and can be so incapacitating that ...

Can epidural patch help post puncture headache?

So far, the therapeutic epidural blood patch is the only treatment for which there is enough evidence to recommend its routine use for severe cases of post-dural puncture headache.

What is a PDPH headache?

Post-dural puncture headache (PDPH) may occur following any procedure in which a needle pierces the dura membrane of the spine and subsequently causes spinal fluid to leak out through the puncture hole. The resulting leakage reduces the spinal fluid pressure to the extent that the membrane at the base of the skull, ...

How many patients were included in the sumatriptan-Fioricet protocol?

Sixteen patients agreed to sumatriptan-Fioricet protocol and were included in this case series. The demographics, medical history and indications are presented in Table 1. Four patients had diagnostic lumbar puncture with 20 gauge lumbar puncture needle and one had lumbar myelogram. Two patients received lumbar epidural steroid injections and two received cervical epidural steroid injections without apparent wet taps during the procedure, but reported headaches with postural component afterwards. Three surgical patients had single shot uncomplicated spinal anesthesia with 25 gauge Quincke needles. Of the four obstetric patients in the series, technical difficulties were noted in all. Ot these, three patients had spinal anesthesia with 25 gauge Quincke spinal needles for cesarean section after multiple failed epidural attempts with 18 gauge Tuohy epidural needles. Only one patient had documented wet tap with an 18 gauge Tuohy needle and had vaginal delivery under intravenous sedation. Seven patients had the onset of headaches on the same day, five the following day and four after two days.

What is a case study?

A case study, by definition, is not conducted in a rigorous scientific manner (ie. a prospective, double blind, randomized study, having a control group and large sample size) and yet it can provide insight and practical observations useful to the practitioner. This case report of the treatment of PDPH with a sumatriptan-Fioricet combination experienced a success rate of 81%. The authors believe this technique can be used as a first line therapy for PDPH, while keeping epidural blood patch in reserve for resistant cases and patients with cranial nerve palsies, and cardiovascular disease.

How long does Fioricet last?

Fioricet at a dosage of one tablet every four hours was prescribed on an as-needed basis by the oral route for three days. If the patient had no relief from the initial dose of sumatriptan, an option of a second dose of sumatriptan or epidural blood patch was offered to the patient.

What is the success rate of a blood patch for PDPH?

Originally described by Gormley, 17 the epidural blood patch remains the best supported method of therapy of PDPH with claimed success rates of between 92% and 100% 18 especially when performed immediately after the dural puncture.

What is the purpose of sumatriptan?

Sumatriptan is a selective serotonin agonist causing cerebral vasoconstriction and is highly effective in migraine attacks . During PDPH, the body attempts to compensate intracranial hypotension with cerebral vasodilation. 1 These changes are similar to migraine attacks. Sumatriptan counteracts the vasodilation and causes relief from PDPH. Increase in blood flow velocities was recorded by transcranial doppler studies in internal carotid and middle cerebral arteries probably secondary to vasoconstriction of the large basal intracranial arteries after sumatriptan therapy. 2 The efficacy and safety of sumatriptan in the treatment of migraine attacks has been established. 3 However, coronary spasm, acute myocardial infarction, cardiac arrest and dysrrhythmias have been reported from its use. 4-9 Sumatriptan should be avoided in patients with known coronary artery disease or with significant cardiovascular risk factors. Cardiovascular monitoring and resuscitation equipments are mandatory.

Does cranial nerve palsy show diplopia?

None had signs of diplopia, blurred vision or signs of cranial nerve palsy. Every patient was on oral mild narcotics without significant relief. One patient was on intravenous narcotics, one had intravenous caffeine and one already had EBP with recurrence of headache.

What is a headache after a dural puncture?

Postdural Puncture Headache (PDPHA), as defined by the International Headache Society, is any headache that develops within 5 days of dural puncture and is not better explained by another cause. While the classic symptoms of PDPHA highlight a positional component that worsens with sitting or standing and improves with lying flat, a small minority of patients have the opposite symptomatology. The headache is usually frontal or occipital in nature, and sometimes associated with neck stiffness, auditory symptoms, visual disturbances, and nausea. Most present within the first 48 hours, though a quarter of cases may occur 3 days following dural puncture. Symptoms are believed to be due to leakage of CSF from the dural tear, which creates traction on the brain and cranial nerves.

How long does it take for a headache to occur after a dural puncture?

Most present within the first 48 hours, though a quarter of cases may occur 3 days following dural puncture. Symptoms are believed to be due to leakage of CSF from the dural tear, ...

How long does it take for PDPHA to resolve?

Most PDPHA resolve spontaneously within 2 weeks, but several studies have shown that in a small subset of patients, symptoms may persist for more than 6 weeks. Therefore, prompt follow-up and treatment of PDPHA is recommended.

Is cesarean section more protective than vaginal delivery?

Obesity may be protective, and cesarean section is definitely more protective than vaginal delivery among parturients. The latter is theorized to be due to a lack of straining during the second stage of labor, which may worsen CSF leakage.

Is PDPHA a headache?

Commonly associated with the obstetric population, PDPHA is, however, not the leading cause of headache in these patients. More common are tension headaches and preeclampsia. The established incidence of PDPHA is around 1%, based on findings from the SCORE project which studied both spinal anesthetics and accidental dural puncture ...

Can you put blood patches after a dural puncture?

While there is no proven method of prevention, some anesthesia providers place prophylactic epidural blood patches after suspected dural puncture during epidural placement. Standardized trials of this technique have shown mixed results.

INTRODUCTION

Postural headaches following interventions that disrupt meningeal integrity are most commonly labeled postdural puncture headaches (PDPHs). This terminology has been officially adopted in the International Classification of Headache Disorders and is used in this section.

HISTORY AND CURRENT RELEVANCE

As one of the earliest recognized complications of regional anesthesia, PDPH has a long and colorful history. Dr. August Bier noted this adverse effect in the first patient to undergo successful spinal anesthesia on August 16, 1898 ( Figure 1 ).

PATHOPHYSIOLOGY

It has long been accepted that PDPH results from a disruption of normal CSF homeostasis. However, despite a great deal of research and observational data, the pathophysiology of PDPH remains incompletely understood.

CLINICAL PRESENTATION AND CHARACTERISTICS

Although many clinical variations have been described, most cases of PDPH are characterized by their typical onset, presentation, and associated symptoms.

RISK FACTORS

Risk factors for PDPH can be broadly categorized into patient characteristics and procedural details.

PREVENTION

Although prophylaxis is most simply thought of as preventing any symptoms of PDPH, in the clinical context this issue is deceptively complex. It is important to appreciate that significant “prevention” may encompass a number of other endpoints, such as a reduced incidence of severe PDPH, a shorter duration of symptoms, or decreased need for EBP.

DIAGNOSTIC EVALUATION

Postdural puncture headache remains a diagnosis of exclusion. Although headache following meningeal puncture will naturally be suspected to be PDPH, it remains critical to rule out other etiologies ( Table 1 ).

What is a headache caused by a dural puncture?

Such headache caused by dural puncture is known as Postdural puncture headache. The loss of cerebrospinal fluid decreases pressure within subarachnoid space, which is expressed with symptoms like severe pounding headache. Dural puncture can be minor or major.

What causes a postural puncture headache?

Postdural puncture headache is caused by continuous leakage of cerebrospinal fluid from laceration, crack or hole in dural membrane. The three membranes cover brain and Spinal cord. Cerebrospinal fluid lies between 2nd and 3rd layer of membrane, also known as mater. The 3 membranes are known as pia, arachnoid and dura mater.

What is the effect of loss of CSF on the brain?

The loss of CSF causes increased concentration of CSF protein and lymphocytes count. Magnetic Resonance Imaging (MRI)- MRI study of brain and spinal cord is performed. The tiny needle puncture over dura is often not observed in MRI films and images.

What is the subarachnoid space?

The subarachnoid space around spinal cord is also connected to brain. Loss of cerebrospinal fluid following continuous leak through puncture or lacerated dural cracks and decreases the pressure within the subarachnoid space surrounding spinal cord and brain.

How is spinal anesthesia performed?

Spinal Anesthesia- Spinal anesthesia is performed by placing needle in subarachnoid space. The local anesthesia is injected through the needle in to subarachnoid space. In few cases multiple attempts are made to place needle in epidural space. The dural puncture causes tiny hole in dura and subarachnoid mater, which closes immediately after removal of needle because of retraction of elastic fibers of membrane. In few cases less than 0.1% the hole does not close and CSF leak continues. The continuous leak of CSF results in symptoms of headache.

Why does the dural puncture close?

The dural puncture causes tiny hole in dura and subarachnoid mater, which closes immediately after removal of needle because of retraction of elastic fibers of membrane. In few cases less than 0.1% the hole does not close and CSF leak continues. The continuous leak of CSF results in symptoms of headache.

Where is the drop of pressure in the subarachnoid space?

Thus the drop of pressure within subarachnoid space is observed in spinal cord as well as brain. Sudden drop of pressure within subarachnoid space covering brain which is enclosed in skull also affects the outline of vessels like arteries, veins and lymphatics.

How long does it take for a PDPH headache to go away?

Between 70% and 80% of cases of PDPH generally resolve within 7 days or less, and between 88% and 95% of the headaches resolve within 6 weeks. In a small minority of cases, the symptoms may persist for weeks or even months. 6

Does lying flat help with headaches?

Lying flat simply alleviates severity of symptoms but does not decrease the incidence of headache. It is important to remember that the theory behind hydrating patients is that patients with relative hypovolemia will produce less CSF. However, once a patient is euvolemic, additional hydration only exacerbates the symptoms of the headache by forcing patients to frequently walk to the bathroom. If a patient is taking oral fluids ab libitum, additional intravenous supplementation is not indicated. Other conservative strategies for ameliorating PDPH focus on countering the vasodilation that occurs as the body attempts to preserve brain homeostasis in the face of decreased intracranial volume due to CSF leakage. Caffeine is a cerebral vasoconstrictor, but normal oral intake does not appear to reduce long-term severity of headache or obviate the need for an epidural blood patch, although there may be some transient benefit. 11 However, as a central nervous stimulant, there have been reports of seizures after high doses of intravenous administration of caffeine, particularly if blood is withdrawn for injection in a blood patch.

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