Older glaucoma medications such as cholinergics (ie, miotics, such as pilocarpine), osmotics, and nonselective adrenergic agonists have a limited role in the treatment of ocular hypertension. They should be considered only if contraindications prevent the use of preferred medications.
Which medications are used in the treatment of open-angle glaucoma of ocular hypertension?
Schuman JS, Katz GJ, Lewis RA, et al. Efficacy and safety of a fixed combination of travoprost 0.004%/timolol 0.05% ophthalmic solution once daily for open-angle glaucoma of ocular hypertension. Am J Ophthalmol. 2005; 140 :242–50.
What are the different types of drugs for glaucoma?
Drugs to treat glaucoma are classified by their active ingredient. These include: prostaglandin analogs, beta blockers, alpha agonists, carbonic anhydrase inhibitors, and rho kinase inhibitors. In addition, combination drugs are available for patients who require more than one type of medication.
What is glaucoma/intraocular hypertension?
About Glaucoma/Intraocular Hypertension: A group of eye diseases characterised by an increase in intraocular pressure which causes pathological changes in the optic disk and typical defects in the field of vision.
When should we treat ocular hypertension?
However, the ultimate decision of when to treat will be determined by other issues such as life expectancy, the general health of the patient and the number of risk factors. Clearly, the treatment of only high-risk patients with ocular hypertension should be considered. Research Support, N.I.H., Extramural
What medication is used for ocular hypertension?
Within this class, the alpha2 selective agonist brimonidine is the most commonly used for the treatment of ocular hypertension. Apraclonidine is another alpha2-selective agonist, but it is believed to have more of an allergic potential, so it rarely is used as a long-term medication.
Which of the following drug is commonly used in the treatment of glaucoma?
Acetazolamide (Diamox®): an oral medication.
What is the best medication for glaucoma?
Glaucoma treatment most often starts with these. They're used to help the fluid in your eyes drain better....Examples of this type of drop include:Bimatoprost (Lumigan)Latanoprost (Xalatan)Tafluprost (Zioptan)Travoprost (Travatan Z)
Which antihypertensive drug may also be used to treat glaucoma?
Clonidine. Clonidine is the first available a-2 agonist, for the treatment of glaucoma. Clonidine is a lipophilic molecule, which is a relatively selective a-2 adrenoceptor agonist with some a-1 adrenoceptor agonistic activity. It crosses the blood brain barrier and causes systemic hypotension.
What is ocular hypertension?
Ocular hypertension is when the pressure inside the eye (intraocular pressure or IOP) is higher than normal. With ocular hypertension, the front of the eye does not drain fluid properly. This causes eye pressure to build up. Higher than normal eye pressure can cause glaucoma.
What is the safest medication for glaucoma?
Next came apraclonidine, brand name Iopidine, marketed by Alcon. I did much of the clinical work on apraclonidine, a relatively selective alpha-2 agonist. It is probably the safest drug we have seen so far in the therapy of glaucoma.
What is the first-line drug for glaucoma?
Bimatoprost, based on the efficacy, safety and ease of use, has been approved as a first-line treatment for glaucoma, and well positioned among the first-choices in glaucoma medical therapy.
What is the first-line of treatment for glaucoma?
Formal visual field testing (perimetry) is a mainstay of glaucoma diagnosis and management. Eye drops, commonly nonspecific beta-blocker or prostaglandin analog drops, generally are the first-line treatment to reduce intraocular pressure.
How do eye drops help with glaucoma?
The most common treatment for glaucoma is prescription eye drops. They work by lowering the pressure in your eye and preventing damage to your optic nerve. These eye drops won’t cure glaucoma or reverse vision loss, but they can keep glaucoma from getting worse. If your doctor prescribes eye drops for glaucoma, you’ll need to use them every day.
What are the side effects of glaucoma?
Most people don’t have problems with glaucoma medicines. But there’s a small chance that you could develop: 1 Stinging, itching, burning, and redness in your eye 2 Blurry vision 3 Changes in your eye color or the skin around your eye 4 Headaches 5 Dry mouth 6 Changes in your energy level, heartbeat, or breathing
What are some examples of eye drops?
Examples include: Prostaglandins, like latanoprost (Xalatan), travoprost (Travatan Z), tafluprost (Zioptan), and bimatoprost (Lumigan) Rho kinase inhibitor, like netarsudil (Rhopressa)
Can glaucoma be stopped?
Stick with it. Some people with glaucoma stop using their eye drops after a while. They may forget, get out of the habit, or think the medicine isn’t helping. But remember, glaucoma eye drops won’t make you feel different or improve your vision. They prevent your vision from getting worse.
Can you take eye drops for glaucoma?
Before you start taking glaucoma medicines, tell your doctor about other medicines, supplements, or vitamins you take. Eye drops for glaucoma may affect how those other medicines work.
Drugs used to treat Intraocular Hypertension
The following list of medications are in some way related to, or used in the treatment of this condition.
Further information
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