What is y90 used for in radiation therapy?
Radioembolization, also called Y-90 Selective Internal Radiation Therapy (SIRT), is a minimally invasive liver-directed therapy for liver cancer that either arises from the liver (primary liver cancer or hepatocellular carcinoma) or has metastasized to the liver from other organs most commonly the colon or rectum (secondary liver cancer) that cannot be removed with surgery.
What is y90 for liver cancer?
Jan 27, 2017 · Jeremy McBride, M.D., an interventional radiologist with Mayo Clinic Health System, suggested a minimally invasive radiation treatment known as Y-90 to strategically attack the tumors invading Turnbull’s liver. The treatment works by injecting tiny particles into the arteries feeding the tumors with blood.
What is yy-90 SIRT used to treat?
Our team of experts believes that Yttrium-90 (Y-90) radiotherapy is the best option for you at this time. Y-90 radiotherapy sends radiation directly into the blood vessels that feed the tumors. This treatment does not cure liver tumors. But, it often controls or shrinks them. After this therapy, your doctors may advise other options such as
What is yttrium-90 Y-90 test?
Radioembolization (Y90) Radioembolization is a minimally invasive procedure that combines embolization and radiation therapy to treat liver cancer. Tiny glass or resin beads filled with the radioactive isotope yttrium Y-90 are placed inside the blood vessels that feed a tumor.
Does Y90 cure cancer?
The treatment is not a cure for cancer in the liver, but it has been shown to prolong lives for months or years and to greatly improve the quality of life of cancer patients. Patients experience few, if any, side effects from Y90 treatment, which is performed in an outpatient setting.
How does Y90 treatment work?
In Y-90 radiotherapy, millions of tiny radioactive beads are injected directly into the arteries that supply blood to your tumor. These beads will stay in the blood vessels around your tumor(s). This allows very strong radiation to reach the tumors directly.
What are the side effects of Y90 treatment?
The most common side effect after Y-90 radiotherapy is fatigue (feeling very tired). This can be mild or severe. It can last up to a few weeks. Other side effects include: • Poor appetite • Mild abdominal pain • Slight fever • Nausea These symptoms should slowly go away over 1 to 2 weeks.
How many Y90 treatments can you have?
Patients are typically limited to two treatments, although doctors can take another approach — only with concentrated chemotherapy and larger particles — once radiation limits are reached.Jan 27, 2017
Are you radioactive after Y-90 treatment?
The Y90 has a half-life of 64.2 hours. This means that it will be non-radioactive in about a month's time.Oct 31, 2019
How long does Y-90 last?
With this procedure, radioactive (Y90) resin or glass-based particles are delivered by catheter and provide a continuing radiation dose for approximately three and a half weeks to targeted tissues. The results typically are documented via imaging three and six months out.Apr 15, 2014
How long is Y-90 mapping?
The mapping procedure will take about 2-4 hours. Dr. Christenson will place a small plastic tube (called a catheter) into one of the vessels in your groin and direct the catheter to the blood vessels in your liver.
Can radiation shrink liver tumors?
Radiation therapy can shrink or kill tumor cells. At Memorial Sloan Kettering, we may recommend this approach if you have a primary liver tumor that can't be removed with surgery. It can be used alone or in combination with chemotherapy or other treatments.
What is the difference between TACE and Y-90?
Y90 is better tolerated with a smaller side effect profile when compared to TACE therapy. However, Y90 is an expensive treatment option, which isn't feasible for certain patient populations, such as those on Medicaid. Y90 is a very well-tolerated procedure.
Is y90 a brachytherapy?
The Yttrium-90 irradiates from within and can be viewed as "internal" radiation or "brachytherapy." Radioembolization is a palliative, not a curative, treatment. Patients may benefit by extending their lives and improving their quality of life.
Is microwave an ablation?
Microwave ablation (MWA) is a minimally-invasive treatment for cancer. MWA uses ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) to guide placement of a needle-like probe into a tumor. MWA uses microwaves to heat and destroy the tumor. Doctors use MWA for the same indications as RFA.
What is Y90 treatment?
In contrast to most nuclear medicine applications, Y90 is therapeutic and designed to treat rather than simply diagnose. It is estimated that 75% to 95% of patients see improvement from treatment, potentially extending their lives or improving survival rates. In this post we’ll take a look at Y90, what it is, and how it works.
What is Y90 therapy?
When is Y90 therapy indicated? Hepatic (liver) tumors (lesions or masses) may originate as a primary cancer of the liver such as hepatocellular cancer (90% of primary liver cancers) or may be another form of cancer that has metastasized to the region . There are many treatment options available for hepatic lesions.
How to avoid radiation?
As a precaution, the following is recommended: 1 Contact with others is limited over the week as the radiation diminishes 2 Patients shouldn’t sleep in the same bed as a partner over that week 3 Patients should avoid public transport that requires them to sit next to another person for more than two hours 4 Patients should avoid close contact with children or pregnant women.
What is Y90 used for?
Yttrium-90 (Y90) is a commonly used isotope within the nuclear medicine and radiation oncology communities for radiation therapy. When used for the treatment, Y90 is relied upon to provide a prescribed amount of radiation to a targeted area. Y90 is most commonly used during a radioembolization therapy, an internal radiation therapy.
Is radioembolization painful?
The radioembolization procedure is generally painless for patients. For a small number of patients, ulcers may develop in the stomach or duodenum – these are treated as any other type of ulcer.
What is the Ergo camera?
A camera such as the Ergo with its digital technology captures all data without any holes and provides a more accurate picture. After the mapping process is complete, the images are further analyzed by the medical team and then an exact amount of Y90 is prescribed to treat the lesion.
Does Y90 help with liver cancer?
Radioembolization with Y90 utilizes nuclear medicine to treat hepatic lesions. Most patients will see some improvement in their liver and it may improve survival and life expectancy rates, depending on the type of cancer. This treatment is not recommended in cases of severe kidney or liver dysfunction, abnormal blood clotting or blockages ...
What is Y-90 SIRT?
What is Radioembolization (Y-90 SIRT)? Radioembolization, also called Y-90 Selective Internal Radiation Therapy (SIRT), is a minimally invasive liver-directed therapy for liver cancer that either arises from the liver (primary liver cancer or hepatocellular carcinoma) or has metastasized to the liver from other organs most commonly ...
How long after SIRT procedure can you return home?
S ince you will have received a radioactive treatment, there are some simple precautions that need to be taken during the first 24 hours following the SIRT procedure. Very importantly, there is no danger in returning home immediately after the procedure is completed.
What is the liver's blood supply?
The liver is unique because it has two blood supplies—the hepatic artery and the portal vein. The normal liver receives about 75 percent of its blood supply through the portal vein and only 25 percent through the hepatic artery. But when a tumor grows in the liver, it receives almost all of its blood supply from the hepatic artery. ...
How long does it take for a tumor to decay?
The whole procedure may take around 60–90 minutes.
What are the benefits of a liver transplant?
Other benefits include: Delays the time to tumor progression (the time it takes for a tumor to regrow) Extends overall survival rate. Potentially downsizes or downstages tumors for liver resection, ablation, or transplantation giving patients a genuine chance for rehabilitation. Provides palliation of symptoms.
Can liver cancer be treated with radiation?
This typically happens after one treatment but treatments can be repeated if necessary to achieve complete tumor destruction. The targeted nature and high level of precision of this therapy enable doctors to deliver more radiation to the liver tumors than would be possible using conventional external beam radiotherapy.
What is Y90 in medical terms?
Radioembolization (Y90) Radioembolization is a minimally invasive procedure that combines embolization and radiation therapy to treat liver cancer. Tiny glass or resin beads filled with the radioactive isotope yttrium Y-90 are placed inside the blood vessels that feed a tumor. This blocks the supply of blood to the cancer cells ...
What is IV line?
You may be connected to monitors that track your heart rate, blood pressure, oxygen level and pulse. A nurse or technologist will insert an intravenous (IV) line into a vein in your hand or arm to administer a sedative. This procedure may use moderate sedation. It does not require a breathing tube.
How does radiation help cancer patients?
This blocks the supply of blood to the cancer cells and delivers a high dose of radiation to the tumor while sparing normal tissue. It can help extend the lives of patients with inoperable tumors and improve their quality of life.
Where does the liver get its blood from?
Normal liver tissue receives about 75 percent of its blood supply from the portal vein and about 25 percent from the hepatic artery and its branches. When a tumor grows in the liver, it receives almost all of its blood supply from the hepatic artery.
What is the treatment for cancer?
This form of treatment is called internal radiation therapy. In radioembolization, tiny glass or resin beads called microspheres are placed inside the blood vessels that feed a tumor in order to block the supply of blood to the cancer cells. Once these microspheres, which are filled with the radioactive isotope yttrium Y-90, ...
How big is a catheter?
A catheter is a long, thin plastic tube that is considerably smaller than a "pencil lead", or approximately 1/8 inch in diameter. Millions of glass beads, amounting to about half a teaspoon full, each of which is smaller in diameter than a human hair, deliver the ionizing radiation.
Can contrast material cause allergic reactions?
There is a very slight risk of an allergic reaction if contrast material is injected. Any procedure that places a catheter inside a blood vessel carries certain risks. These risks include damage to the blood vessel, bruising or bleeding at the puncture site, and infection.
Treatments & Procedures
Radioembolization (Yttrium-90 embolization or selective internal radiation therapy)
Risks
Small risks of bleeding or infection. Radiation can cause harm to the normal liver, and non-target radiation damage to the stomach, bowel, or lung can rarely occur.
Post-procedure
Bed rest for 2-6 hours after each procedure, then discharge home. Although the radioactivity emitted from a treated patient is minimal, some radiation precautions may be prescribed by your interventional radiologist. A post-embolization syndrome consisting of fatigue, pain, and/or nausea can often occur, and may last several days or more.
Follow-up
If liver cancer is present in both lobes of the liver, a second radiation delivery session targeting the opposite side of the liver may be arranged for several weeks after the first.
For More Information
For more information or to schedule an appointment, please visit the contact us page.
What Can I Expect from The Procedure?
- One to two weeks before the delivery of the Y90 to the liver tumors, you will have appointments with your interventional radiologist, who will test your blood and perform an angiogram—an imaging procedure in which dye is injected into the bloodstream and X-ray images are taken. T…
Are There Any Risks?
- The procedure is relatively safe when performed by an experienced interventional radiologist. Major complications include: 1. Post-embolization syndrome consisting of consisting of pain, nausea, and low-grade fever 2. Irritation of the stomach or small intestine, including ulcers 3. Fatigue, which is typically significant and can last from a few days to a few weeks
After The Procedure
- Most patients are scheduled early in the day in our outpatient office and recover in their own private room, going home in the afternoon. Imaging is performed on the day of the procedure to confirm the location within the liver where the radiation particles have been deposited. For the next week you may experience a low-grade fever, lethargy, or fatigue. Pain is not a common sid…
Follow Up
- We will schedule a follow up appointment with you about two weeks after the procedure. Chemotherapy can typically be restarted one to two weeks after the procedure. Follow up imaging, such as CT, MRI, or PET CT, is usually performed approximately eight weeks after the procedure.
What Is Y90?
When Is Y90 Therapy Indicated?
- Hepatic (liver) tumors (lesions or masses) may originate as a primary cancer of the liver such as hepatocellular cancer (90% of primary liver cancers) or may be another form of cancer that has metastasized to the region. There are many treatment options available for hepatic lesions. The choice for treatment is generally based on how they present, physician preference and treatmen…
Y90 Mapping and Its Role with Radioembolization Therapy
- There is a great deal of planning prior to performing a Y90 radioembolization. Here are a few steps: 1. The first step in the process is referred to as the “mapping”. The mapping process involves a very similar process to the radioembolization treatment itself; the patient is brought into interventional radiology and the vasculature of the liver tumor is examined. During this time…
Patient Precautions and Side-Effects
- The radioembolization procedure is generally painless for patients. For a small number of patients, ulcers may develop in the stomach or duodenum – these are treated as any other type of ulcer. Post-embolization syndrome (PES) is a side effect that is experienced by a few patients. This consists of vomiting, nausea, fever and pain, usually within the first 72 hours after treatmen…
Final Thoughts
- Radioembolization with Y90 utilizes nuclear medicine to treat hepatic lesions. Most patients will see some improvement in their liver and it may improve survival and life expectancy rates, depending on the type of cancer. This treatment is not recommended in cases of severe kidney or liver dysfunction, abnormal blood clotting or blockages of the bile ducts. Radioembolization ma…