Treatment FAQ

what is treatment for stage 1 endometrisl cancer

by Dr. Melissa Harris V Published 2 years ago Updated 1 year ago
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If you are diagnosed with stage I endometrial cancer, surgery to remove the cancerous tumor may be the only treatment necessary. During surgery, your uterus and cervix, and generally both ovaries and fallopian tubes, may be removed. A biopsy of your lymph nodes may also be performed to check for cancer cells.

Medication

Your treatment plan will depend on:

  • the type of primary cancer you have
  • the stage of your cancer
  • which bones are involved
  • prior cancer treatments
  • your overall health

Procedures

Uterine cancer is not fatal when it is diagnosed and treated in the early stages. Generally, a 5-year survival rate for patients in stage 1 of uterine cancer is 90%….Is uterus cancer fatal? What are the treatment options for Stage 2 uterine cancer? With stage 2 cancer, your doctor may or may not recommend additional treatment after a hysterectomy.

Therapy

Usually surgery for endometrial cancer includes:

  • Total hysterectomy (surgical removal of the uterus)
  • Bilateral salpingo-oophorectomy (removal of both ovaries and Fallopian tubes)
  • Biopsy of the omentum, a fat pad in the pelvis
  • Removal of lymph nodes in the pelvis and lower abdomen

What is the life expectancy of someone with uterine cancer?

Treatments may include one or more of these:

  • Removing the rectal cancer with surgery
  • Surgery to create a colostomy and bypass the rectal cancer (a diverting colostomy)
  • Using a special laser to destroy the cancer within the rectum
  • Placing a stent (hollow metal tube) within the rectum to keep it open; this does not require surgery
  • Chemoradiation therapy
  • Chemo alone

What is the prognosis for Stage 1 uterine cancer?

What is the best treatment for uterine cancer?

What are the treatment options for Stage 1 rectal cancer?

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Is chemo required for stage 1 endometrial cancer?

Chemo is not used to treat stage I and II endometrial cancers. In most cases, a combination of chemo drugs is used.

Does Stage 1 uterine cancer require chemo or radiation?

Stage I endometrioid cancers For women with higher grade tumors, radiation will likely be recommended after surgery. Vaginal brachytherapy (VB), pelvic radiation, or both can be used. Some younger women with early endometrial cancer may have their uterus removed without removing the ovaries.

What is the most effective treatment for endometrial cancer?

Treatment for endometrial cancer is usually with surgery to remove the uterus, fallopian tubes and ovaries. Another option is radiation therapy with powerful energy. Drug treatments for endometrial cancer include chemotherapy with powerful drugs and hormone therapy to block hormones that cancer cells rely on.

Can you survive stage 1 uterine cancer?

When uterine cancer is detected and treated early on, it is not lethal. In general, individuals with stage 1 uterine cancer had a 90% 5-year survival rate. The 5-year uterine cancer survival rate, on the other hand, varies depending on how far the disease has gone.

Is Stage 1 uterine cancer serious?

This stage is not included in the FIGO staging system. Stage 1 uterine cancer: The cancer is only growing in the body of the uterus. It may also be growing into the glands of the cervix but is not growing into the supporting connective tissue of the cervix. The cancer has not spread to lymph nodes or distant sites.

Can Stage 1a endometrial cancer come back?

Endometrial cancer is most likely to come back within the first few years after treatment, so an important part of your treatment plan is a specific schedule of follow-up visits after treatment ends. How often you need to be seen depends mostly on what stage and grade the cancer was.

What is Stage 1a endometrial cancer?

Stage IA and stage IB endometrial cancer. In stage IA, cancer is in the endometrium only or less than halfway through the myometrium (the muscle layer of the uterus). In stage IB, cancer has spread halfway or more into the myometrium.

Does hysterectomy cure endometrial cancer?

Surgery is often the main treatment for endometrial cancer and consists of a hysterectomy, often along with a salpingo-oophorectomy, and removal of lymph nodes. In some cases, pelvic washings are done, the omentum is removed, and/or peritoneal biopsies are done.

What are the symptoms of stage 1 uterine cancer?

Signs and symptoms of endometrial cancer include unusual vaginal bleeding or pain in the pelvis.Vaginal bleeding or discharge not related to menstruation (periods).Vaginal bleeding after menopause.Difficult or painful urination.Pain during sexual intercourse.Pain in the pelvic area.

Can endometrial cancer come back after hysterectomy?

The chances of endometrial cancer recurrence vary based on a number of factors that are unique to each patient, including age and the stage and spread of the initial cancer. Endometrial cancer is most likely to recur in the first three years after the initial treatment, though late recurrence is also possible.

Is endometrial cancer a death sentence?

While endometrial cancer is the most common gynecologic cancer, it is typically the most treatable: The five-year survival rate is nearly 82%.

What is Grade 1 cancer of the uterus?

Grades 1 and 2 endometrioid cancers are type 1 endometrial cancers. Type 1 cancers are usually not very aggressive and they don't spread to other tissues quickly. Type 1 endometrial cancers are thought to be caused by too much estrogen.

What are the risks of endometrial cancer?

Risk factors for endometrial cancer include the following: Taking estrogen-only hormone replacement therapy (HRT) after menopause. Taking tamoxifen to prevent or treat breast cancer. Obesity.

How is endometrial biopsy done?

Endometrial biopsy: The removal of tissue from the endometrium (inner lining of the uterus) by inserting a thin, flexible tube through the cervix and into the uterus. The tube is used to gently scrape a small amount of tissue from the endometrium and then remove the tissue samples.

What is the name of the cancer that forms in the lining of the uterus?

Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium. The endometrium is the lining of the uterus, a hollow, muscular organ in a woman’s pelvis. The uterus is where a fetus grows. In most nonpregnant women, the uterus is about 3 inches long. The lower, narrow end of the uterus is the ...

How to know if a cancer has spread?

It is important to know the stage in order to plan treatment. Certain tests and procedures are used in the staging process. A hysterectomy (an operation in which the uterus is removed) will usually be done to treat endometrial cancer. Tissue samples are taken from the area around the uterus and checked under a microscope for signs of cancer to help find out whether the cancer has spread.

Where is stage IB cancer found?

In stage IB, cancer has spread halfway or more into the myometrium. In stage I, cancer is found in the uterus only.

What is the procedure to remove tissue from the inner lining of the uterus?

A pathologist views the tissue under a microscope to look for cancer cells. Dilatation and curettage: A procedure to remove samples of tissue from the inner lining of the uterus. The cervix is dilated and a curette (spoon-shaped instrument) is inserted into the uterus to remove tissue.

How does chemo work?

When chemotherapy is taken by mouth or injected into a vein or muscle , the drugs enter the bloodstream and can reach cancer cells throughout the body ( systemic chemotherapy ). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas ( regional chemotherapy ).

What is the treatment for stage 1 endometrial cancer?

During surgery, your uterus and cervix, and generally both ovaries and fallopian tubes, may be removed. A biopsy of your lymph nodes may also be performed to check for cancer cells.

What is the procedure to remove endometrial cancer?

Surgery generally includes: Removal of the uterus and the cervix (hysterectomy) Removal of both of the ovaries and fallopian tubes (bilateral salpingo-oophorectomy)

What is removed during a total hysterectomy?

In a total hysterectomy, the uterus and cervix are removed. In a total hysterectomy with salpingo-oophorectomy, (a) the uterus plus one (unilateral) ovary and fallopian tube are removed; or (b) the uterus plus both (bilateral) ovaries and fallopian tubes are removed.

What is radiation therapy?

Radiation therapy is a cancer treatment that uses high-energy X-rays or other types of radiation to eliminate cancer cells or stop cancer growth. Radiation therapy for endometrial cancer is given by our experienced team of radiation oncologists.

Why do we need chemotherapy after surgery?

Chemotherapy drugs are usually administered after surgery to eliminate remaining cancer cells or keep them from returning. On occasion, chemotherapy drugs will be given as supplemental treatment to radiation therapy (called "radiation sensitizing" chemotherapy) that can help make the radiation work better.

What is the BWH for endometrial cancer?

For cases of endometrial cancer that require complex imaging treatment, you will be cared for in an innovative operating and research environment developed specifically at Brigham and Women's Hospital (BWH) in 2011.

What is the treatment for cancer?

Sometimes treatment involves chemotherapy (drugs that eliminate cancer cells or stop them from dividing), hormonal therapy (a treatment that blocks the action of naturally occurring hormones), or immunotherapy (a treatment that boosts your immune system’s ability to fight cancer).

What is the procedure to diagnose endometrial cancer?

Hysteroscopy. During hysteroscopy, your doctor uses a thin, lighted instrument (hysteroscope) to view the inside of your uterus. Tests and procedures used to diagnose endometrial cancer include: Examining the pelvis. During a pelvic exam, your doctor carefully inspects the outer portion of your genitals (vulva), ...

What happens after endometrial cancer diagnosis?

After you receive a diagnosis of endometrial cancer, you may have many questions, fears and concerns. Every person eventually finds a way to cope with an endometrial cancer diagnosis. In time, you'll find what works for you. Until then, you might try to:

How to get a sample of cells from inside the uterus?

To get a sample of cells from inside your uterus, you'll likely undergo an endometrial biopsy. This involves removing tissue from your uterine lining for laboratory analysis. Endometrial biopsy may be done in your doctor's office and usually doesn't require anesthesia. Performing surgery to remove tissue for testing.

What is hormone therapy?

Hormone therapy involves taking medications to lower the hormone levels in the body. In response, cancer cells that rely on hormones to help them grow might die. Hormone therapy may be an option if you have advanced endometrial cancer that has spread beyond the uterus.

What is the best way to kill cancer cells?

Radiation therapy uses powerful energy beams, such as X-rays and protons, to kill cancer cells. In some instances, your doctor may recommend radiation to reduce your risk of a cancer recurrence after surgery. In certain situations, radiation therapy may also be recommended before surgery, to shrink a tumor and make it easier to remove.

What tests are used to determine the stage of cancer?

Tests used to determine your cancer's stage may include a chest X-ray, a computerized tomography (CT) scan, positron emission tomography (PET) scan and blood tests. The final determination of your cancer's stage may not be made until after you undergo surgery to treat your cancer.

How does chemotherapy work?

Chemotherapy uses chemicals to kill cancer cells. You may receive one chemotherapy drug, or two or more drugs can be used in combination. You may receive chemotherapy drugs by pill (orally) or through your veins (intravenously). These drugs enter your bloodstream and then travel through your body, killing cancer cells.

What is the treatment for stage 2 endometrial cancer?

Treatment for this stage often includes the removal of the uterus, surrounding tissues, upper portion of the vagina, ovaries, fallopian tubes and lymph nodes in the pelvis. Radiation therapy is often given following the surgery.

What is the best treatment for cancer?

Surgery is often recommended first to remove as much of the cancer as possible, though sometimes the cancer has spread too far to make surgery an option. A combination of radiation therapy and chemotherapy are typically also used.

How to contact a cancer specialist?

Our cancer experts ensure each patient’s treatment plan is tailored to address their individual case. You can request a consultation by calling 1-888-663-3488 or submitting a new patient registration form online. We do not require referrals.

What are the factors that affect endometrial cancer?

One factor that influences a patient’s endometrial cancer treatment options is the stage of her malignancy at the time of diagnosis. While other factors such as a woman’s overall health, health care preferences and specific type of cancer will also affect her ideal course of treatment, it is often helpful for women who have just been diagnosed ...

Where does stage 4 endometrial cancer spread?

Stage 4. Stage 4 endometrial cancer has spread to the bladder or bowel, or to the lymph nodes outside the pelvic region and other distant organs . In most cases of stage 4 endometrial cancer, surgery is not an option, as the cancer has spread too far to be removed.

Can endometrial cancer spread beyond the uterus?

Stage 1 endometrial cancer has not spread beyond the uterus. In many cases, surgery to remove the uterus, and often the ovaries, is recommended. Those who have higher grade tumors may also need additional treatment such as radiation therapy or vaginal brachytherapy.

What is the treatment for stage 1 uterine cancer?

The standard treatment for stage I uterine cancer is a total abdominal hysterectomy (removal of the uterus) and bilateral salpingo-oophorectomy (removal of the fallopian tubes and ovaries) with or without removal of the pelvic and para-aortic lymph nodes. Despite complete surgical resection of all cancer, 5-20% of patients will experience ...

What is stage I uterine cancer?

Patients diagnosed with Stage I uterine cancer have cancer that has not spread outside the uterus. Stage IA is cancer confined to the inner layer of cells of the uterus (endometrium). Stage IB is cancer that invades less than one half of the muscle wall of the uterus.

What is the goal of radiation therapy?

The goal of radiation therapy is to eradicate any remaining cancer cells after surgery. Adjuvant radiation therapy may consist of brachytherapy and/or external beam radiation. Women with stage I uterine cancer treated with surgery and postoperative radiation therapy have a 5-year survival of 80-90% and a local cancer recurrence rate of only 4-8%.

What is the name of the cancer in the uterus?

Uterine (End ometrial) Cancer FACT SHEET. Uterine cancer, also known as endometrial cancer, is a disease that forms in the endometrium, which is the tissue lining the uterus. LEARN MORE >.

How many patients with stage 1 cancer will recur?

Despite complete surgical resection of all cancer, 5-20% of patients will experience recurrence of their cancer. This is because some patients with stage I cancer have microscopic cancer cells, called micrometastases, that have spread outside the uterus and therefore were not removed by surgery. These cancer cells cannot be detected with any ...

Can brachytherapy be used after surgery?

Brachytherapy without external beam radiation therapy has been used to prevent local recurrences after surgery. In a clinical trial that involved 102 women with stage IB and IC uterine cancer who were treated with brachytherapy following surgery, cancer recurrences occurred in 7% of women, 4% of which were local recurrences.

Does radiation therapy help with uterine cancer?

The doctors concluded that postoperative radiation therapy reduced local recurr ences of cancer following surgery for stage I uterine cancer, but did not improve survival. Adjuvant Brachytherapy: Brachytherapy treatment involves the placement of a radioactive isotope into the vagina and may have fewer side effects than external beam radiation.

Identifying the Uterine Cancer Stage

Knowing the stage helps doctors in uterine cancer prognosis. To determine the stage of uterine cancer, doctors employ two methods. The International Federation of Gynecology and Obstetrics developed one approach (FIGO). The TNM staging method of the American Joint Committee on Cancer is the other. The two procedures are nearly identical.

Uterine Cancer Stages

Cancer hasn’t gone beyond your uterus at this stage. It can also affect the glands in your cervix, a thin channel at the bottom of your uterus, but not the tissues.

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Medically reviewed by
Dr. Khutaija Bano
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Treatment involves chemotherapy, hormone therapy, radiation, surgery and palliative care.
Medication

Chemotherapy: Therapy where drugs are used to kills cancer cells.

Carboplatin . Paclitaxel . Cisplatin . Doxorubicin


Hormone therapy: To increase the amount of progesterone in the body.

Progestin

Procedures

Hysterectomy: Surgical procedure which involves the removal of uterus.

Therapy

Radiation therapy:Therapy where powerful energy beams are used to kill abnormal cancerous cells.

Specialist to consult

Oncologist
Specializes in the diagnosis and treatment of cancer.
Gynecologist
Specializes in the health of the female reproductive systems and breasts.

Preparing For Your Appointment

  • Stage III endometrial cancers have spread outside of the uterus. If the surgeon thinks that all visible cancer can be removed, a hysterectomy is done and both ovaries and fallopian tubes are removed. Sometimes women with stage III cancers need a radical hysterectomy. A pelvic and p…
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