what is the treatment indicated if prescribed 80 mg of statin drugs

-Exposure to this drug is approximately doubled with concomitant use of lomitapide; therefore, if initiating lomitapide, reduce simvastatin by 50% or for patients who have tolerated 80 mg/day chronically, simvastatin should be decreased to 40 mg/day.

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What is a typical statin drug regimen?

Memory loss. Damage to your kidneys. Damage to your liver. Bad problems with your muscles. Type 2 diabetes or high blood sugar. Adults and teens can take statins. Most people don’t have side effects from statins, but you shouldn’t take them if you’re pregnant, nursing or have certain types of liver disease.

Who should take statins?

Oct 30, 2015 · Evaluation of muscle symptoms in 420 statin-naïve people in one prospective randomized trial revealed that the incidence of myalgia (muscle pain) was 9.4% for individuals taking 80 mg of atorvastatin daily over six months, compared to 4.6% for those taking a placebo . According to the Arzneiverordnungs-Report (Drug Prescription Report), about 4.7 million people …

How much does a statin drug cost?

Mar 18, 2022 · Statins are drugs that can lower your cholesterol. They work by blocking a substance your body needs to make cholesterol. Lowering cholesterol isn't the only benefit associated with statins. These medications have also been linked to a lower risk of heart disease and stroke. These drugs may help stabilize the plaques on blood vessel walls and reduce the …

What are statins used for?

Statin Dosage; Low-intensity (LDL-C reduction <30%) Moderate-intensity (LDL-C reduction 30% to <50%) High-intensity (LDL-C reduction >50%) Atorvastatin: NA: 10 to 20 mg: 40 to 80 mg: Fluvastatin: 20 to 40 mg: 40 mg 2×/day; XL 80 mg: NA: Lovastatin: 20 mg: 40 mg: NA: Pitavastatin: 1 mg: 2 to 4 mg: NA: Pravastatin: 10 to 20 mg: 40 to 80 mg: NA: Rosuvastatin: NA: 5 to 10 mg: …

What happens if you take 80 mg of atorvastatin?

Is 80 mg of statin too high?

Why is simvastatin 80 mg not recommended?

When are statins indicated?

Is 80mg atorvastatin safe?

What are the side effects of atorvastatin calcium 80 mg?

Is simvastatin 80mg a high intensity statin?

When Should statins be stopped in elderly?

What are the side effects of simvastatin 80 mg?

What do statins treat?

Who should take statins the debate continues?

Can you stop take statin if your cholesterol is normal?

Should You Be on A Statin?

Whether you need to be on a statin depends on your cholesterol levels and other risk factors for cardiovascular disease. Your doctor will consider...

Healthy Lifestyle Is Still Key For Preventing Heart Disease

Risk factors for heart disease and stroke are: 1. Smoking 2. High cholesterol 3. High blood pressure 4. Diabetes 5. Being overweight or obese 6. Fa...

Consider Statins A Lifelong Commitment

You may think that once your cholesterol goes down, you can stop taking statin medication. But if the drug helped lower your cholesterol, you'll li...

The Side Effects of Statins

Statins are well-tolerated by most people, but they do have side effects. Some side effects go away as the body adjusts to the medication. But alwa...

What Other Benefits Do Statins have?

Statins may have benefits other than just lowering your cholesterol. One promising benefit seems to be their anti-inflammatory properties, which he...

Weighing The Risks and Benefits of Statins

You should not take statins if you are pregnant or have some forms of advanced liver disease.When thinking about whether you should take statins fo...

How old do you have to be to take statins?

The U.S. Preventive Services Task Force recommends low- to moderate-dose statins in adults ages 40 to 75 who have one or more risk factors for heart and blood vessel disease and at least a 1 in 10 chance of having a cardiosvascular disease event in the next 10 years.

Can statins be tolerated?

Statins are tolerated well by most people, but they can have side effects. Some side effects go away as the body adjusts to the medication. But tell your doctor about any unusual signs or symptoms you might have after starting statin therapy. Your doctor may want to decrease your dose or try a different statin.

Do people with heart conditions need statins?

Not everyone with a heart condition needs to use a statin. Guidelines from the U.S. Preventive Services Task Force, American College of Cardiology and American Heart Association suggest four main groups of people who may be helped by statins:

How do statins work?

By Mayo Clinic Staff. Statins are drugs that can lower your cholesterol. They work by blocking a substance your body needs to make cholesterol. Lowering cholesterol isn't the only benefit associated with statins.

Do statins lower cholesterol?

Lowering cholesterol isn't the only benefit associated with statins. These medications have also been linked to a lower risk of heart disease and stroke. These drugs may help stabilize the plaques on blood vessel walls and reduce the risk of certain blood clots. A number of statins are available for use in the United States.

What is the best cholesterol level for a heart attack?

Low-density lipoprotein (LDL) cholesterol. Aim to keep this "bad" cholesterol under 100 mg/dL, or 2.6 mmol/L. If you have a history of heart attacks or you're at a very high risk of a heart attack or stroke, you may need to aim even lower (below 70 mg/dL, or 1.8 mmol/L).

Can statins help with high cholesterol?

If your risk is very high — for example, you've had a heart attack in the past — a statin may be helpful even if you don't have high cholesterol. Besides cholesterol, other risk factors for heart disease and stroke are: Tobacco use. Lack of exercise.

Do statins reduce cholesterol?

Of course, statins inhibit the production of cholesterol –they do this very well. Nowhere is the failure of our medical system more evident than in the wholesale acceptance of cholesterol reduction as a way to prevent disease–have all these doctors forgotten what they learned in Biochemistry 101 about the many roles of cholesterol in the human biochemistry? Every cell membrane in our body contains cholesterol because cholesterol is what makes our cells waterproof–without cholesterol we could not have a different biochemistry on the inside and the outside of the cell. When cholesterol levels are not adequate, the cell membrane becomes leaky or porous, a situation the body interprets as an emergency, releasing a flood of corticoid hormones that work by sequestering cholesterol from one part of the body and transporting it to areas where it is lacking. Cholesterol is the body’s repair substance: scar tissue contains high levels of cholesterol, including scar tissue in the arteries.

How do statins help with inflammation?

If statins work, they do so by reducing inflammation, not because they lower cholesterol. Statins block the production of mevalonate leading to inhibition of platelet clumping and reduction of inflammation in the artery walls. However, simple changes in the diet can achieve the same effect without also cutting off the body’s vital supply of cholesterol: 1 Avoid trans fats, known to contribute to inflammation 2 Avoid refined sugars, especially fructose, known to stimulate clumping of the blood platelets 3 Take cod liver oil, an excellent dietary source of anti-inflammatory vitamin A, vitamin D and EPA 4 Eat plenty of saturated fats, which encourage the production of anti-inflammatory prostaglandins 5 Take evening primrose, borage or black currant oil, sources of GLA which the body uses to make anti-inflammatory prostaglandins 6 Eat foods high in copper, especially liver; copper deficiency is associatied with clot formation and inflammation in the arteries 7 Eat coconut oil and coconut products; coconut oil protects against bacteria and viruses that can lead to inflammation in the artery wall 8 Avoid reduced-fat milks and powdered milk products (such as powdered whey); they contain oxidized cholesterol, shown to cause irritation of the artery wall

Is hypercholesterolemia a disease?

Hypercholesterolemia is the health issue of the 21st century. It is actually an invented disease, a “problem” that emerged when health professionals learned how to measure cholesterol levels in the blood. High cholesterol exhibits no outward signs–unlike other conditions of the blood, such as diabetes or anemia, diseases that manifest telltale symptoms like thirst or weakness–hypercholesterolemia requires the services of a physician to detect its presence. Many people who feel perfectly healthy suffer from high cholesterol–in fact, feeling good is actually a symptom of high cholesterol!

Does squalene cause cancer?

Squalene, the immediate precursor to cholesterol, is in turn the biochemical precursor to a whole family of steroid hormones; research indicates that squalene inhibits blood vessel formation in tumors, raising the possibility that it may have anti-cancer effects.

What hormones are produced by the adrenal cortex?

The adrenal cortex also produces sex hormones, including testosterone, estrogen and progesterone, out of cholesterol.

What are the side effects of Lipitor?

The most common side effect is muscle pain and weakness, a condition called rhabdomyolysis, most likely due to the depletion of Co-Q 10, a nutrient that supports muscle function. Dr. Beatrice Golomb of San Diego, California is currently conducting a series of studies on statin side effects. The industry insists that only 2-3 percent of patients get muscle aches and cramps but in one study, Golomb found that 98 percent of patients taking Lipitor and one-third of the patients taking Mevachor (a lower-dose statin) suffered from muscle problems. 4 A message board devoted to Lipitor at forum.ditonline.com (update 09 JUL 2007: reader alerted us the forum is now defunct) contained more than 800 posts, many detailing severe side effects. The Lipitor board at www.rxlist.com contains more than 2,600 posts (click on Message Boards at upper left and then choose Lipitor; also note that as of 09 JUL 2007 there are 3,857 messages).

What is the condition of tingling and pain in the hands and feet?

Polyneuropathy, also known as peripheral neuropathy, is characterized by weakness, tingling and pain in the hands and feet, as well as difficulty walking. Researchers who studied 500,000 residents of Denmark, about 9 percent of that country’s population, found that people who took statins were more likely to develop polyneuropathy. 11 Taking statins for one year raised the risk of nerve damage by about 15 percent–about one case for every 2,200 patients. For those who took statins for two or more years, the additional risk rose to 26 percent.

Can you take statins with a prescription?

Although statins are still a go-to medicine, there is no one-size-fits all prescription. And if they don’t help you enough (along with diet and exercise), or you can’t take them because of side effects, there are also other types of cholesterol-lowering medicines.

How do statins work?

And that could cut your chance of a heart attack or stroke. Statins work in your liver. They block an enzyme that helps your body make cholesterol.

Can statins cause muscle pain?

All medicines can have side effects. With statins, the most common one is muscle pain. Anywhere from 5% to 20% of people who take statins report having it. And it's more common among people taking high doses. But it's not clear if those muscle symptoms are actually related to statins, or if something else is to blame.

When will statins be updated?

Written by Shawn Radcliffe — Updated on April 16, 2020. A year after the release of new guidelines for treating high cholesterol, doctors and patients are still confused about just who needs to take statin drugs. Last fall, the American College of Cardiology (ACC) and the American Heart Association ...

Do you need to monitor LDL levels after statin?

Another aspect of the guidelines that has created some confusion is the belief that, because there are no more LDL targets, doctors no longer need to do ongoing monitoring of LDL blood levels after a patient starts taking a statin. This is not the case.

What is the AHA guidelines?

Last fall, the American College of Cardiology (ACC) and the American Heart Association (AHA) released new guidelines for the treatment of cholesterol to prevent heart attacks and strokes, amid a continuing rise in the rate of heart disease in the Unit ed States. Though the guidelines were years in the making and have received a large amount ...

Can statins cause memory loss?

Statins are not without side effects. These include muscle pain, confusion, flushing, and rarely liver damage or memory loss. Statins and Diabetes Risk: What You Need to Know ». The guidelines are clear about which groups of people could benefit most from therapy — both medications like statins and lifestyle changes like eating better ...

What is risk management?

Risk management, rather than focusing solely on lowering cholesterol, means looking at someone’s entire risk profile, which includes whether they have high blood pressure or established heart disease, are current or former smokers, or have a strong family history of the disease.

What is the purpose of atorvastatin?

Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.

Does atorvastatin lower cholesterol?

Atorvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood). Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, ...

Does atorvastatin cause pain in the arms?

Common atorvastatin side effects may include: joint pain; stuffy nose, sore throat; diarrhea; or. pain in your arms or legs. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Can atorvastatin cause kidney failure?

Atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Can you take atorvastatin while pregnant?

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking this medicine and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Can grapefruit juice be taken with atorvastatin?

It can raise triglyceride levels and may increase your risk of liver damage. Grapefru it and grapefruit juice may interact with atorvastatin and lead to potentially dangerous effects. Avoid drinking more than 1 liter per day of grapefruit juice while taking this medicine.

Can you breastfeed with atorvastatin?

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking this medicine. To make sure this medicine is safe for you, tell your doctor if you have ever had: liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or.

How effective are statins?

Statin therapy reduces the risk for a heart attack or other cardiovascular event by as much as 48 percent. , depending on the level of risk factors you have. In fact, statins are so effective that nearly 32 million Americans take them.

What statins are prescribed for high cholesterol?

If you need high-intensity statin therapy, your doctor is likely to prescribe atorvastatin (Lipitor) or rosuvastatin (Crestor).

What is statins used for?

What are statins? Statins are a class of medication used to reduce the levels of unhealthy LDL cholesterol in your bloodstream. LDL cholesterol is a waxy, fatty substance that sticks to the blood vessels of your heart and the walls of your arteries. This can make your arteries harden. It also may form plaques that block the normal flow of blood.

Can statins cause heart attacks?

It also may form plaques that block the normal flow of blood. If plaques break away from the wall of the artery or blood clots form on them, you can have a heart attack or stroke. Statins reduce your body’s ability to manufacture LDL cholesterol. And they work.

How does statin therapy work?

Statins reduce your body’s ability to manufacture LDL cholesterol. And they work. Statin therapy reduces the risk for a heart attack or other cardiovascular event by as much as 48 percent. , depending on the level of risk factors you have.

Is it safe to take statins?

So, which statin is safest? It depends on a variety of factors. Some statins are safer for you if you have certain medical conditions. That is because there are known drug interactions between medications and individual statins.

What is the LDL level of a diabetic?

your LDL cholesterol level is 190 mg/dL or greater. you have diabetes and high cholesterol levels and other risk factors for cardiovascular disease. If you need high-intensity statin therapy, your doctor is likely to prescribe atorvastatin (Lipitor) or rosuvastatin (Crestor).