Treatment FAQ

what is the treatment for pancreatic insufficiency

by Margaret Parker Published 3 years ago Updated 2 years ago
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Treatment for pancreatic exocrine insufficiency includes support to stop smoking and alcohol consumption, dietary consultation, enzyme replacement therapy and a structured follow-up of nutritional status and the effect of treatment.

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  • Take digestive enzymes at the beginning of your meal or snack, and the right amount of them. “Work with your oncologist and/or dietitian .” Marie Durbin
  • Eat small, frequent meals. ...
  • Find what foods work for you. ...
  • Eat your food with minimal fluids. ...
  • Exercise. ...
  • Know where the nearest bathrooms are. ...
  • Get resources. ...
  • Build a support system. ...

What should I do for pancreatic insufficiency?

There’s no cure for exocrine pancreatic insufficiency (EPI), a chronic condition characterized by an inability to digest certain nutrients, especially fat. But EPI can be managed with a type of medication called pancreatic enzyme replacement therapy (PERT), which consists of enzymes that aid digestion.

Can pancreatic insufficiency be cured?

There is no cure for chronic pancreatitis, but the related pain and symptoms may be managed or even prevented. Since chronic pancreatitis is most often caused by drinking, abstinence from alcohol...

Does pancreatitis have a cure?

• The symptoms of EPI can be a lot like other medical conditions that affect the stomach and bowels.1-4,7-11This can sometimes make EPI hard to diagnose. That’s why it’s important to be open and honest with your doctor about all of your stomach and bowel problems • Tell your doctor about:

Why is epi hard to diagnose?

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What is the best treatment for pancreatic insufficiency?

Apart from a healthy diet, the main treatment for EPI is pancreatic enzyme replacement therapy (PERT). You take prescription pills that replace the enzymes your pancreas isn't making. These enzymes break down your food so you can more easily digest and absorb it. You have to take them during your meals.

Can pancreatic insufficiency be cured?

You can't cure EPI, but pancreatic enzyme replacement therapy can greatly reduce uncomfortable digestive symptoms. Follow your healthcare provider's recommendations for taking PERT, and be sure to take it with every meal or snack. A dietitian can help you get the fats, nutrients and vitamins you need for good health.

Is Pancreatic Insufficiency serious?

Damage to the cells producing pancreatic enzymes leads to exocrine pancreatic insufficiency, which is a serious problem leading to malnutrition, complications, and poor quality of life.

How do you treat pancreatic insufficiency naturally?

8 Tips on Managing Exocrine Pancreatic InsufficiencyTake digestive enzymes at the beginning of your meal or snack, and the right amount of them. ... Eat small, frequent meals. ... Find what foods work for you. ... Eat your food with minimal fluids. ... Exercise. ... Know where the nearest bathrooms are. ... Get resources.More items...•

What are the first signs of pancreatic insufficiency?

Symptoms of pancreatic insufficiencyabdominal pain and tenderness.loss of appetite.feelings of fullness.weight loss and diarrhea.

Can you live a normal life with pancreatic insufficiency?

If your condition is well managed, it's possible to live a healthy life — even into your advanced years — when you have EPI.

What foods should be avoided with pancreatic insufficiency?

Avoidfried, creamy, or cheesy foods, such as pastries. You'll also want to avoid trans fat, a hydrogenated oil and particularly unhealthy type of fat that's often found in packaged food, says Massey, and steer clear of alcohol. While it may take some planning, it's possible to eat a healthy, satisfying diet.

What happens if you don't treat pancreatic insufficiency?

Exocrine pancreatic insufficiency (EPI) occurs when the pancreas doesn't make enough enzymes. Chronic pancreatitis is a risk factor for both EPI and pancreatic cancer. Without the right treatment, EPI can cause malnutrition.

What happens if pancreatic insufficiency is not treated?

If left untreated, exocrine pancreatic insufficiency can lead to feeling malnourished, fatigued and weak. This is due to the poor absorption of vitamins and nutrients. Eventually, it can lead to thinning bones (osteoporosis) or anemia (a deficiency of red blood cells).

What foods irritate the pancreas?

There are a few things you must completely avoid, such as alcohol and fried/greasy/high fat foods (such as creamy sauces, fast food, full fat meat and dairy, and anything fried). These foods can cause your pancreas to release more enzymes at once than it normally would, leading to an attack.

What vitamin is good for the pancreas?

A multivitamin daily, containing the antioxidant vitamins A, C, E, D, the B-complex vitamins, and trace minerals, such as magnesium, calcium, zinc, and selenium. Omega-3 fatty acids, such as fish oil, 1 to 2 capsules or 1 to 2 tbsp. of oil daily, to help reduce inflammation and improve immunity.

How is pancreatic insufficiency diagnosed?

The 3 main EPI tests used to aid in diagnosis are:Fecal elastase test. This test measures the amount of elastase, an enzyme produced by the pancreas, in your stool. ... Fecal fat test. This test checks the amount of fat in your stool. ... Pancreatic function test.

What is the role of pancreatic juice?

The pancreatic juice plays a pivotal role in the digestion and absorption of nutrients [5]. Pancreatic enzyme secretion is stimulated during the cephalic[6] and gastric[7] phases to a certain degree, but the most important stimulation occurs during the intestinal phase, when chyme enters the duodenum.

What is the test for exocrine pancreatic function?

Exocrine pancreatic function can be measured by so-called direct pancreatic function tests . In these tests, pancreatic secretion is stimulated by secretin and/or cerulein[45] or by the ingestion of a standard test meal[46].

How many lipase units are needed for pancreatic enzyme replacement?

The dose should be in proportion to the fat content of the meal, usually 40-50000 lipase units per main meal, and half the dose is required for a snack.

Does smoking cause pancreatitis?

Smoking is a risk factor for pancreatic cancer, acute pancreatitis and CP[53], and is also associated with an increased probability of reduced pancreatic exocrine function based on the endoscopic pancreatic function test in cases with CP[54].

How to treat pancreatic insufficiency?

For severe pancreatic insufficiency, vitamin supplements are necessary part of your treatment to treat vitamin deficiencies. You may also need medication to treat abdominal pain.

What test can be done to check for pancreatic inflammation?

Another test called "fecal elastase-1" may also be done to look for the presence of an important digestive enzyme in your stool. Other tests that may help find out if you have pancreatic damage or inflammation include: CT scan, which uses powerful X-ray to take detailed pictures of your body.

Why does the pancreas not produce enough enzymes?

Pancreatic insufficiency occurs when the exocrine function is deficient so that the pancreas does not produce enough pancreatic enzymes that help digest food.

Why do you need to take antacids?

They are taken during meals for best results. You may also need to take antacids to prevent premature break down of the pancreatic enzymes in the stomach before they start to work.

What causes low levels of pancreatic enzymes?

Damage to the pancreas can lead to pancreatic insufficiency, resulting in low levels of pancreatic enzymes. This leads to malabsorption of food, which is not properly used as energy by the body. Your pancreas may be damaged by: chronic inflammation. pancreatic surgery.

What is the function of the pancreas?

It is about six inches long and has a head and a tail. Its most important functions are to produce hormones that help regulate blood sugar levels and pancreatic juices ...

How to prevent malabsorption?

This will help prevent symptoms of malabsorption and at the same time provide enough energy and nutrition your body needs. Eating frequent small meals rather than big meals to improve digestion. Avoiding alcohol, which can damage your pancreas over time and make it more difficult for your body to absorb fat.

Lifestyle and Home Remedies

To improve your symptoms of EPI, talk to your doctor about potential lifestyle changes and accommodations that you can implement. The following are some steps you can take to improve your quality of life with EPI: 2

Prescriptions

If your doctor suspects that you have EPI, they may prescribe prescription medications to manage symptoms, including pancreatic enzyme replacement therapy (PERT).

Summary

If you are diagnosed with EPI, your doctor may recommend prescription medications and dietary and lifestyle modifications, such as cutting back or quitting smoking or drinking alcohol, as these lifestyle choices can promote inflammation.

A Word From Verywell

EPI can be greatly improved with PERT prescriptions. Pancreatic functioning can be improved when drinking and smoking are avoided or eliminated completely. That said, consult with your gastroenterologist about supplementing your low-fat meals with fat-soluble vitamins (A, D, E, K), as many people with EPI are low in these vitamins.

How to treat exocrine pancreatic insufficiency?

If your pancreas doesn’t function properly, you may need to do the digestive work for it. A healthy diet, the right supplements, and enzyme replacement therapy can all help you treat EPI. By Beth W. Orenstein Medically Reviewed by Robert Jasmer, MD. Last Updated: January 2, 2020.

What is the purpose of pancreatic enzymes?

Pancreatic enzyme supplement capsules contain a mixture of digestive enzymes, including lipase to break down fat, protease to assist with digestion of protein, and amylase for carbohydrates , according to PCA. The more fat in your meal, the higher the dose of enzymes you’ll likely need, Whitcomb says.

What is it called when your pancreas doesn't produce enzymes?

If your pancreas doesn’t produce the enzymes needed for proper digestion, you have what’s called exocrine pancreatic insufficiency ( EPI ). It’s a treatable condition, and to best understand your options, it helps to first have a working knowledge of the condition itself. “EPI is malnutrition specifically linked to the failure ...

Why do I need a low fat diet?

Depending on what’s causing your symptoms, your doctor may recommend you stick to a low-fat diet, in part because EPI leads to difficulty absorbing nutrients from food, according to Gardner. A low-fat diet can help minimize the pain, bloating, gas , and stomach discomfort that can occur with fat maldigestion.

What to eat for children with CF?

People with EPI are advised to eat plenty of fruits and vegetables, which are good sources of vitamins and minerals, Gardner says.

Does smoking cause pancreatitis?

Excessive drinking can damage the pancreas, according to the NIDDK , and smoking elevates your risk for pancreatic diseases, including cancer and pancreatitis, according to PCA. NEWSLETTERS. Sign up for our Digestive Health Newsletter!

Can you take enzymes with antacids?

If you take the enzymes with antacids, they may not be as effective, according to the Pancreatic Cancer Action Network.

How to reduce inflammation in pancreas?

reduce alcohol use or abuse. stimulate pancreatic duct drainage using dilation, or stents. surgery. There are reports of the use of antioxidants (selenium, vitamin A, vitamin C, and vitamin E) to reduce ongoing inflammation.

What is the condition where the pancreas does not make enough of a specific enzyme?

What is pancreatic insufficiency? Pancreatic Insufficiency (EPI) is a condition which occurs when the pancreas does not make enough of a specific enzyme the body uses to digest food in the small intestine. The pancreas is a glandular organ. That means the pancreas secretes juices that maintain the proper function of the body.

What happens when the pancreas is damaged?

When the pancreas becomes damaged, pancreatic enzymes are not produced, and malabsorption results. Malabsorption is the result of food that is not properly converted into usable energy by the digestive system. The pancreas may become damaged by:

Can pancreatitis cause malabsorption?

Patients with chronic pancreatitis may not have any symptoms . However, with ongoing destruction of the gland and loss of its function, symptoms of malabsorption may develop. Chronic pancreatitis can also manifest with abdominal pain, and diabetes.

Can pancreatic cancer cause cancer?

previous pancreatic surgery. it is rarely caused by cancer. Additionally, there are genetic factors that may cause damage to the pancreas: cystic fibrosis, a disease damages glandular organs by creating mucus that impairs their function. Shwachman-Diamond Syndrome, a rare autosomal recessive disorder.

Is chronic pancreatitis a sign of alcohol abuse?

Chronic pancreatitis is a serious risk factor resulting from too many instances of pancreatic inflammation. It has many causes, but chronic alcohol abuse is the most common one in western countries. Chronic pancreatitis and subsequent insufficiency can also run in families (hereditary pancreatitis and cystic fibrosis).

How do you treat pancreatitis?

How do health care professionals treat pancreatitis? 1 a hospital stay to treat dehydration with intravenous (IV) fluids and, if you can swallow them, fluids by mouth 2 pain medicine, and antibiotics by mouth or through an IV if you have an infection in your pancreas 3 a low-fat diet, or nutrition by feeding tube or IV if you can’t eat

What to do if you have a blockage in your pancreas?

If you have stones blocking your pancreatic duct, your doctor may use a procedure to break up and remove the stones. Treatment for acute or chronic pancreatitis may include a hospital stay to treat dehydration and prescribe pain medicine, antibiotics, and nutrition.

How long does it take for pancreatitis to go away?

Mild acute pancreatitis usually goes away in a few days with rest and treatment. If your pancreatitis is more severe, your treatment may also include: Surgery. Your doctor may recommend surgery to remove the gallbladder, called cholecystectomy, if gallstones cause your pancreatitis.

What can a doctor prescribe for diabetes?

Your doctor may prescribe or provide the following: Medicines and vitamins. Your doctor may give you enzyme pills to help with digestion, or vitamins. NIH external link. A, D, E, and K if you have malabsorption. He or she may also give you vitamin B-12. NIH external link. shots if you need them. Treatment for diabetes.

What is the treatment for dehydration?

a hospital stay to treat dehydration with intravenous (IV) fluids and, if you can swallow them, fluids by mouth. pain medicine, and antibiotics by mouth or through an IV if you have an infection in your pancreas. Your doctor may send you to a gastroenterologist or surgeon for one of the following treatments, depending on the type ...

Where is the surgery done for pancreatitis?

Surgery is done in a hospital, where you may have to stay a few days. In patients who do not get better with other treatments, surgeons may perform surgery to remove your whole pancreas, followed by islet auto-transplantation. Islets are groups of cells in your pancreas that make hormones, including insulin.

Can you smoke if you have pancreatitis?

Health care professionals strongly advise people with pancreatitis to stop smoking, even if your pancreatitis is mild or in the early stages. Smoking with acute pancreatitis, especially if it’s caused by alcohol use, greatly raises the chances that your pancreatitis will become chronic.

How to help with pancreatic pain?

Severe pain may be relieved with options such as endoscopic ultrasound or surgery to block nerves that send pain signals from the pancreas to the brain. Enzymes to improve digestion. Pancreatic enzyme supplements can help your body break down and process the nutrients in the foods you eat.

How to treat pancreatitis in hospital?

Treatment. Initial treatments in the hospital may include: Fasting. You'll stop eating for a couple of days in the hospital in order to give your pancreas a chance to recover. Once the inflammation in your pancreas is controlled, you may begin drinking clear liquids and eating bland foods.

What is the procedure called to open the bile duct?

A procedure called endoscopic retrograde cholangiopancreatography (ERCP) uses a long tube with a camera on the end to examine your pancreas and bile ducts.

What is the best way to check for gallstones?

Computerized tomography (CT) scan to look for gallstones and assess the extent of pancreas inflammation. Endoscopic ultrasound to look for inflammation and blockages in the pancreatic duct or bile duct. Magnetic resonance imaging (MRI) to look for abnormalities in the gallbladder, pancreas and ducts.

What tests are used to diagnose pancreatitis?

Tests and procedures used to diagnose pancreatitis include: Blood tests to look for elevated levels of pancreatic enzymes. Stool tests in chronic pancreatitis to measure levels of fat that could suggest your digestive system isn't absorbing nutrients adequately. Computerized tomography (CT) scan to look for gallstones and assess the extent ...

How to recover from pancreatitis?

Lifestyle and home remedies. Once you leave the hospital, you can take steps to continue your recovery from pancreatitis, such as: Stop drinking alcohol. If you're unable to stop drinking alcohol on your own, ask your doctor for help. Your doctor can refer you to local programs to help you stop drinking. Stop smoking.

Can pancreatitis cause pain?

Pancreatitis can cause severe pain. Your health care team will give you medications to help control the pain. Intravenous (IV) fluids. As your body devotes energy and fluids to repairing your pancreas, you may become dehydrated.

What vitamins do you need to eat if you have pancreatic insufficiency?

Your doctor may prescribe vitamin and mineral supplements to help you maintain proper levels of the fat-soluble vitamins A, D, E, and K . Eating healthy with EPI and cystic fibrosis (CF)

What is the condition of exocrine pancreatic insufficiency?

Exocrine pancreatic insufficiency (EPI) is a condition characterized by deficiency of the exocrine pancreatic enzymes, resulting in the inability to digest food properly, or maldigestion. Who gets EPI?

What is the best treatment for EPI?

Pancreatic enzyme replacement therapies. Your doctor may start you on a prescription treatment called pancreatic enzyme replacement therapy, or PERT. PERTs are the main treatment for EPI—they replace the digestive enzymes that your pancreas isn’t producing anymore.

Can EPI cause GI problems?

In addition to preventing adequate digestion, EPI produces uncomfortable gastrointestinal (GI) symptoms. Only your doctor can tell if your GI symptoms are due to EPI or another digestive ...

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Lifestyle and Home Remedies

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Exocrine pancreatic insufficiency (EPI) develops when your pancreas doesnt make or release enough digestive enzymes. This leaves undigested food in your intestines and causes gut pain, bloating, and diarrhea. Severe EPI can cause fatty, loose stools and weight loss from malnutrition. A variety of conditions can cause …
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Prescriptions

Summary

A Word from Verywell

Adverse effects

Causes

  • To improve your symptoms of EPI, talk to your doctor about potential lifestyle changes and accommodations that you can implement. The following are some steps you can take to improve your quality of life with EPI:2 1. Maintain a healthy diet:When you have EPI, take extra care with what and how you eat. Work with a dietitian so you can know exactly how to get proper nutrition …
See more on verywellhealth.com

Treatment

  • If your doctor suspects that you have EPI, they may prescribe prescription medications to manage symptoms, including pancreatic enzyme replacement therapy (PERT).
See more on verywellhealth.com

Diet

  • If you are diagnosed with EPI, your doctor may recommend prescription medications and dietary and lifestyle modifications, such as cutting back or quitting smoking or drinking alcohol, as these lifestyle choices can promote inflammation. Long-term treatment goals for patients with EPI will depend on the severity of your pancreas function at the tim...
See more on verywellhealth.com

Interactions

  • EPI can be greatly improved with PERT prescriptions. Pancreatic functioning can be improved when drinking and smoking are avoided or eliminated completely. That said, consult with your gastroenterologistabout supplementing your low-fat meals with fat-soluble vitamins (A, D, E, K), as many people with EPI are low in these vitamins. Additionally, while PERT is an effective treatme…
See more on verywellhealth.com

Definition

Risks

Prevention

  • Doctors can sometimes treat EPI at its root cause, like with celiac disease, for example, says Timothy B. Gardner, MD, an associate professor of medicine at the Geisel School of Medicine at Dartmouth in Lebanon, New Hampshire. Otherwise, EPI symptoms need to be treated with diet, vitamin and mineral supplements, and pancreatic enzyme replacement therapy (PERT). The goa…
See more on everydayhealth.com

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