
Medication
- Avoid contact with urine if possible, and wear protective clothing (gloves, etc.) if you need to handle urine.
- Practice good hygiene including careful hand washing.
- Disinfect surfaces where infected pets have urinated (antibacterial disinfectant or diluted bleach solution).
Therapy
What are the symptoms?
- Fever
- Shivering
- Muscle tenderness
- Reluctance to move
- Lethargy
- Increased thirst
- Changes in the frequency or amount of urination
- Dehydration
- Vomiting
- Diarrhea
Nutrition
Your vet is likely to recommend Bordetella and Leptospirosis vaccines, as well as Lyme if you live in a high tick area. All of these vaccines carry a high risk for your dog and don’t work very well. Check the vaccine issues listed on the chart, and also consider these points before vaccinating your dog.
How to identify, treat, and prevent leptospirosis in dogs?
There are three main forms of the disease:
- Hemorrhagic (bleeding). In hemorrhagic disease there is high fever with lethargy and loss of appetite. ...
- Icteric or jaundice (liver). The icteric or jaundice form begins like the hemorrhagic form and many of the clinical signs are the same. ...
- Renal (kidney). The renal form causes kidney failure. ...
What happens when your dog has leptospirosis?
Do you vacinate your dog(s) for Bordetella or leptospirosis?
What are the side effects of leptospirosis in dogs?

Can dogs survive leptospirosis?
With correct and aggressive treatment, your dog with leptospirosis has an 80% survival rate, but their kidney or liver function may be permanently impaired. Thus, you must seek veterinary attention for your dog as soon as they start showing leptospirosis signs.
How long does it take to cure leptospirosis in dogs?
Penicillin, Ampicillin, and Tetracyclines are commonly prescribed to treat leptospirosis in dogs. These antibiotics will also help prevent your pooch from being carriers of the disease. The duration of treatment for antibiotics may take at least four weeks, depending on your vet.
What antibiotic treats leptospirosis in dogs?
Antibiotics such as penicillin, ampicillin, and amoxicillin, are reasonably effective against the acute stages of leptospirosis if begun early. These antibiotics treat the early stages of infection, making the dog feel better, although most affected dogs require intensive care in the veterinary hospital.
What is the best treatment for leptospirosis?
Leptospirosis is treated with antibiotics, such as doxycycline or penicillin, which should be given early in the course of the disease. Intravenous antibiotics may be required for persons with more severe symptoms.
How Long Can dogs live with lepto?
Dogs usually become infected by drinking, swimming or walking through contaminated water. What are the signs of leptospirosis, and how long do they last? Dogs usually get sick one to two weeks after exposure. Illness can last days or weeks and may include fever, chills, vomiting, muscle aches or diarrhea.
What are the early signs of leptospirosis in dogs?
The clinical signs of leptospirosis vary and are nonspecific. Sometimes pets do not have any symptoms. Common clinical signs have been reported in dogs....These include:Fever.Vomiting.Abdominal pain.Diarrhea.Refusal to eat.Severe weakness and depression.Stiffness.Severe muscle pain.More items...
How much doxycycline do I give a dog with leptospirosis?
In most cases, doxycycline has been considered the gold-standard treatment for canine leptospirosis. It is recommended for 14–21 days at a dose of 5–10 mg/kg/day orally, administered with food (5).
How much does it cost to treat leptospirosis in dogs?
Leptospirosis Treatment Cost (and Savings) Pets with leptospirosis can be quite sick and treatment can be very expensive. On average, it costs about $2,000 to diagnose and treat a case of leptospirosis in dogs. This price can increase significantly if your pet's disease is more severe.
How serious is leptospirosis in dogs?
The disease causes serious damage to the kidney and liver, and may be fatal in severe cases. Bacteria are passed in the urine of infected animals and can survive in the environment for long periods of time in warm, stagnant water or moist soil.
How long does it take to cure leptospirosis?
The illness lasts from a few days to 3 weeks or longer. Without treatment, recovery may take several months.
What are the stages of leptospirosis?
Two distinct phases of illness are observed in the mild form: the septicemic (acute) phase and the immune (delayed) phase. In icteric leptospirosis, the 2 phases of illness are often continuous and indistinguishable. At disease onset, clinically predicting the severity of disease is not possible.
Does leptospirosis have a cure?
Leptospirosis is treatable with antibiotics. If an animal is treated early, it may recover more rapidly and any organ damage may be less severe. Other treatment methods, such as dialysis and hydration therapy may be required.
What antibiotics are good for dogs with leptospirosis?
Antibiotics such as penicillin, ampicillin, and amoxicillin, are reasonably effective against the acute stages of leptospirosis if begun early. These antibiotics treat the early stages of infection, making the dog feel better, although most affected dogs require intensive care in the veterinary hospital. An extended course of antibiotics, typically ...
What is leptospirosis in dogs?
What is leptospirosis? Leptospirosis is a bacterial disease of dogs and other mammals that primarily affects the liver or kidneys. The bacteria ( Leptospira) that cause leptospirosis, commonly called leptospires, thrive in water and they have a helical or spiral shape with a characteristic hook on one or both ends.
What causes a dog's skin to turn yellow?
In severe cases, the skin will turn yellow. 3. Renal (kidney). The renal form causes kidney failure. These dogs are very lethargic, anorectic (unwilling to eat), and may vomit. Their breath may have an offensive odor, and ulcers often develop on the tongue.
How long does it take for a dog to get infected by urine?
For instance, when dogs swim in contaminated water, they may become infected through their skin. The incubation period (from infection to onset of clinical signs) is usually four to twelve days.
What test is used to detect leptospirosis?
There are two tests that can be used for the diagnosis of leptospirosis. The DNA-PCR test looks for the presence of genetic material from the Leptospira bacteria in the blood or urine. The MAT (microscopic agglutination test) looks for the presence of antibodies that are formed against leptospirosis.
Can leptospirosis be detected in dogs?
A single test finding of Leptospira antibody, even if the blood level (titer) is high, may not mean that the dog has leptospirosis because infection with less har mful serovars can still result in high antibody ( see handout “ Leptospirosis in Dogs – The Disease and How to Test for It” for more information).
Is leptospirosis common in rural areas?
Outbreaks of the disease are still seen from time to time however, because vaccines protect only against the four most prevalent serovars of Leptospira. Leptospirosis is more common in rural, wooded areas. Increased numbers of cases are seen in the South, Midwest, ...
How Is Leptospirosis in Dogs Spread?
Lepto is spread in one of two ways: by direct transmission or by indirect exposure via an environment that's contaminated with urine from an infected animal.
Clinical Signs of Leptospirosis in Dogs
Many dogs who are infected with lepto don't show any signs at all. Whether they become ill depends on their immune systems and which species of Leptospira bacteria they're exposed to. Not all species of Leptospira cause the disease, and over 250 species have been classified worldwide.
Diagnosing and Treating Leptospirosis in Dogs
A vet will review your dog's oral history, vaccination history, physical exam findings and laboratory tests to diagnose lepto. Your vet may order diagnostic tests, including bloodwork, urinalysis, imaging studies such as an abdominal ultrasound or radiology, and specific tests for lepto.
Preventing Leptospirosis in Dogs
Limit your dog's access to places where Leptospira like to hide, such as marshy and muddy areas, ponds, heavily irrigated pastures and low-lying areas with stagnant surface water.
What to do if your dog has leptospirosis?
If your pet has been confirmed by your veterinarian as having leptospirosis, the appropriate action to take will depend on the nature of contact with your pet. Normal daily activities with your pet will not put you at high risk for leptospirosis infection.
How to treat leptospirosis in animals?
Leptospirosis is treatable with antibiotics. If an animal is treated early, it may recover more rapidly and any organ damage may be less severe. Other treatment methods, such as dialysis and hydration therapy may be required.
What is the best test for leptospirosis in dogs?
Ideally, a combination of serology and organism detection should be used for diagnosis of canine leptospirosis. Serology is the most frequently used diagnostic test for dogs. Acute and convalescent titers may be necessary to confirm a diagnosis; hence, the use of the MAT is preferred over the ELISA. PCR-based tests are widely available, and collection of both blood and urine samples before administration of antibiotics should be considered for maximal sensitivity. The results of all diagnostic tests should be interpreted in light of the animal's vaccination history, clinical signs, and clinicopathologic findings.
Why does leptospirosis cause jaundice in dogs?
In people and dogs, the jaundice of acute leptospirosis appears to be associated with minimal histopathologic changes in the liver, suggesting that it is due to the “cholestasis of sepsis” rather than to hepatocellular damage.
What is the best treatment for dogs?
Doxycycline is the primary drug used for treatment in dogs, along with appropriate supportive care. Polyvalent vaccines are available for prevention. Specific serovars in a geographic area vary, so vaccines with the appropriate types should be used.
Why is it important to have a high index of suspicion for leptospirosis in dogs?
It is, however, extremely important for veterinarians to maintain a high index of suspicion for leptospirosis, because this is a zoonotic disease and has a wide range of clinical presentations in dogs. Any age, breed, or sex of dog is susceptible to leptospirosis, and the diagnosis should not be excluded on the basis of signalment or lifestyle.
What bacterins are available for dogs?
Commercial bacterins for dogs are available for serovars Canicola, Icterohaemorrhagiae, Grippotyphosa, and Pomona. Vaccinated dogs may potentially be susceptible to infection with other serovars, although this has not been tested in an experimental setting. In general, currently available vaccines provide good protection from clinical disease and also appear to reduce renal colonization and urine shedding. Concerns exist regarding hypersensitivity reactions after leptospiral vaccination in dogs, but these appear to be unjustified based on more recent studies and perhaps associated with the use of more highly purified vaccines. Canine challenge studies have demonstrated duration of immunity of at least 1 yr; thus, prior recommendations for vaccinating every 6 mo are no longer justified.
Why does PU/PD occur in dogs?
PU/PD may be due to a decrease in glomerular filtration rate that is sufficient to cause loss of renal concentrating ability without azotemia. However, PU/PD can also be due to nephrogenic diabetes insipidus. Acute liver disease may accompany acute renal failure in dogs with leptospirosis, or it may occur alone.
Why does my dog tremble when he has leptospirosis?
Muscle pain, stiffness, weakness, trembling, or reluctance to move can be seen in dogs with leptospirosis. These may be the result of vasculitis, myositis, or nephritis. Myalgia is commonly reported in human leptospirosis and is associated with the septicemic phase of the disease.
How to treat leptospirosis in dogs?
However, if your pet has been diagnosed with Leptospirosis, steps to prevent infections include the following: 2 1 Avoid contact with urine if possible, and wear protective clothing (gloves, etc.) if you need to handle urine. 2 Practice good hygiene including careful hand washing. 3 Disinfect surfaces where infected pets have urinated (antibacterial disinfectant or diluted bleach solution). 4 Follow your vet's advice for treatment and make sure all medications are given as directed.
What tests are needed for leptospirosis in dogs?
This may include radiographs, various blood and urine tests and ultrasound.
What is the cause of leptospirosis?
Leptospirosis is a bacterial disease caused by a complex group of closely related bacteria of the genus Leptospira. There are several strains that occur in different locations and tend to affect certain species more than others. Leptospira bacteria survive especially well in warm, humid areas, and are often found in stagnant water like ponds.
What is the best way to kill leptospira?
Antibiotics are used to kill Leptospira bacteria and are often given in two stages: one type of antibiotic to treat the initial infection followed up with a different kind of antibiotic to combat the shedding of bacteria in the urine. The earlier treatment is started, the better.
How do dogs get infected?
Dogs can become infected by exposure to contaminated water (both through ingestion or contact with mucous membranes or broken skin), exposure to urine from an infected animal (e.g. contaminated food, bedding, soil, etc.), bite wounds, and ingestion of tissues from infected animals.
How do you know if your dog has leptospira?
The severity of symptoms varies and depends on the dog (age, immune response, vaccination status), the strain of Leptospira, and other factors. Severe cases can be fatal. Signs and symptoms may include: 1 . Fever. Joint or muscle pain (this may manifest as a reluctance to move) Decreased appetite and Lethargy.
How to treat a dog that is sick?
Practice good hygiene including careful hand washing. Disinfect surfaces where infected pets have urinated (antibacterial disinfectant or diluted bleach solution). Follow your vet's advice for treatment and make sure all medications are given as directed. If you suspect your pet is sick, call your vet immediately.
What is the best treatment for leptospirosis in dogs?
Fluid therapy will be the primary treatment for leptospirosis in dogs to reverse any effects of dehydration. If your dog has been vomiting, an anti-vomiting drug, called an antiemetic, may be administered, and a gastric tube can be used to nourish your dog if the inability to eat or keep food down continues.
What is leptospirosis in dogs?
Leptospirosis in Dogs: What It Is and What You Should Know. Leptospirosis in dogs is a bacterial infection that spreads through the bloodstream. Dogs can get leptospirosis from puddles or bodies of water that carry urine from infected wildlife. The bacteria infiltrate a dog’s body by burrowing into their skin.
How do dogs get leptospirosis?
Dogs typically contract leptospirosis through direct contact with urine from an infected animal. Open sores on the skin can increase the chances of contracting this disease. If your dog swims in, passes through, or drinks infected water, or if they come into contact with infected soil or mud, they are at risk.
How long does it take for leptospira to go away?
Keep in mind that Leptospira bacteria may continue to be shed through the urine for several weeks after treatment and apparent recovery from the infection.
Where does leptospirosis spread?
Leptospirosis spreads throughout a dog’s entire body, reproducing in the liver, kidneys, central nervous system, eyes, and reproductive system. Soon after initial infection, your dog will develop a fever and a bacterial infection of the blood, but these symptoms soon resolve as antibodies are produced. The extent in which this bacteria affects the ...
What to do when your dog is being treated?
While your dog is being treated, keep him away from other pets and children. Wear latex gloves when handling your dog in any way, or when handling fluid or waste products from your dog.
Can Leptospira spirochete be transmitted to humans?
The Leptospira spirochete bacteria is zoonotic, meaning that it can be transmitted to humans and other animals from an infected animal. Children are most at risk of acquiring the bacteria from an infected pet. People and pets can be infected and not yet show symptoms.
What are the abnormalities in dogs with leptospirosis?
The most common abnormalities found on routine testing in dogs with leptospirosis include: CBC: increased numbers of white blood cells (indicating infection and tissue damage), decreased numbers of platelets (indicating infection and severe disease), and sometimes, decreased numbers of red blood cells (due to bleeding).
What are the signs of leptospirosis in dogs?
What are the signs of leptospirosis? Severely infected dogs show signs of lethargy, depression, loss of appetite, vomiting, fever, and increased thirst and urination. Dogs may develop jaundice, which means the lining of the mouth and the whites of the eyes turn yellow. In some cases there may be bleeding.
What is the cause of leptospirosis?
Leptospirosis is an infectious disease caused by a type of bacteria called Leptospira. The disease causes serious damage to the kidney and liver, and may be fatal in severe cases. Bacteria are passed in the urine of infected animals and can survive in the environment for long periods of time in warm, stagnant water or moist soil.
What is it called when a dog has leptospira in its urine?
Dogs that have recovered and yet still carry Leptospira in their tissues are called carriers.
Why is DNA PCR difficult for dogs?
Dogs that have been sick for a long time or have only mild signs of illness may be difficult to diagnose by DNA-PCR due to the small numbers of bacteria present. In some cases, dogs that are truly infected may give ...
How do dogs get leptospira?
Leptospira can penetrate the soft lining of the nose, mouth, and eyelid, and can enter the body through open sores and scratches in the skin.
How effective are antibiotics for leptospirosis?
There are two phases of antibiotic treatment: the first phase quickly clears the most serious or acute infection from the body. The second phase clears the low-grade lingering infection found in carrier dogs.
How Do Dogs Get Leptospirosis?
Dogs can contract the disease through direct contact with other infected animals. These infected animals include squirrels, rodents, raccoons, skunks, opossums, and deer.
Types of Leptospirosis
Some strains of Leptospira are more likely to cause the disease than other strains. This is why there are three main types of the disease: hemorrhagic, icteric or jaundice, and renal (kidney) disease.

Symptoms
Prognosis
Causes
Other animals
Specialist to consult
Diagnosis
Signs and symptoms
Treatment
- In people, acute kidney injury due to leptospirosis is often nonoliguric and can be associated with hyponatremia and hypokalemia. These electrolyte changes have also been noted in canine leptospirosis, along with the expected changes of azotemia, hyperphosphatemia, and acidosis of renal failure. Hyperkalemia is also possible. Polyuria and polydipsia (PU/PD) in the absence of a…