Procedures
Testosterone treatment can: Improve muscle mass Deepen the voice Promote growth of facial and body hair Help the reproductive organs to mature Build and maintain bone strength and help prevent osteoporosis in later years Produce a more masculine appearance, which can also help relieve anxiety and ...
Therapy
Dec 01, 2016 · Is there a cure for Klinefelter syndrome (KS)? Currently, there is no way to remove chromosomes from cells to "cure" the XXY condition. But many symptoms can be successfully treated, minimizing the impact the condition has on length and quality of life.
Nutrition
There is no cure for Klinefelter Syndrome (KS). However there are treatments available for the problems associated with the condition. Fertility therapies For some men with KS who have no sperm in their semen, it is possible to take sperm directly from the testes with surgery called microscopic testicular sperm extraction (microTESE).
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Apr 13, 2021 · Treatment for Klinefelter syndrome focuses on improving symptoms and providing support to the individual. We use cookies to enhance your experience. By continuing to browse this site you agree to our use of cookies.
Is there any method to cure Klinefelter syndrome?
Some treatments for the symptoms of Klinefelter syndrome can include: Hormone replacement. Therapy. Surgery. Hormone replacement People with Klinefelter syndrome often have less of the hormone testosterone than typical males. Some boys will not start puberty changes at all, whereas others will start but then stop or regress.
What are the side effects of Klinefelter syndrome?
Experts recommend testosterone replacement, starting during puberty, for proper development of muscles, bones, male sex characteristics such as facial hair, and sexual function. Continued treatment throughout life helps prevent long-term health problems. Testosterone replacement does not cure infertility, however.
What is the prognosis of Klinefelter syndrome?
A number of complications caused by Klinefelter syndrome are related to low testosterone (hypogonadism). Testosterone replacement therapy reduces the risk of certain health problems, especially when therapy is started at the beginning of puberty. By Mayo Clinic Staff Request an Appointment at Mayo Clinic Diagnosis & treatment Sept. 21, 2019 Print
How do you get Klinefelter's syndrome?
Treatments for Klinefelter syndrome There's no cure for Klinefelter syndrome, but some of the problems associated with the condition can be treated if necessary. Possible treatments include: testosterone replacement therapy speech and language therapy during childhood to help with speech development
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What is the most common treatment for Klinefelter syndrome?
Treatment of Klinefelter Syndrome One common treatment is testosterone replacement therapy. It can start at puberty and can spur typical body changes, such as facial hair and a deeper voice. It can also help with penis size and stronger muscles and bones, but it won't affect testicle size or fertility.Sep 22, 2021
How does Klinefelter syndrome affect a person's life?
But the condition can bring challenges later in life. For example, guys with Klinefelter syndrome may be more likely to get some types of cancer and other diseases, like type 2 diabetes and osteoporosis, a condition where the bones become weaker later in life.
How long can a person live with Klinefelter's syndrome?
According to studies, Klinefelter syndrome (KS) can shorten life expectancy up to 2 years depending on whether complications associated with the condition develop. Early detection and treatment, including special educational interventions, may improve the outlook of this disease.Sep 13, 2021
Is Klinefelter syndrome reversible?
Is there a cure for Klinefelter syndrome (KS)? Currently, there is no way to remove chromosomes from cells to "cure" the XXY condition. But many symptoms can be successfully treated, minimizing the impact the condition has on length and quality of life.Dec 1, 2016
Is Klinefelter syndrome a disability?
If you or your dependent(s) are diagnosed with Klinefelter Syndrome and experience any of these symptoms, you may be eligible for disability benefits from the U.S. Social Security Administration.
Can you pass on Klinefelter syndrome?
Klinefelter syndrome is not inherited; the addition of an extra X chromosome occurs during the formation of reproductive cells (eggs or sperm) in one of an affected person's parents.Sep 8, 2020
Which parent is responsible for Klinefelter syndrome?
Klinefelter syndrome is not caused by anything the parents did or did not do. The disorder is a random error in cell division that happens when a parent's reproductive cells are being formed.
Is there a cure coming soon for Klinefelter syndrome?
There's no cure for Klinefelter syndrome, but some of the problems associated with the condition can be treated if necessary. Possible treatments include: testosterone replacement therapy. speech and language therapy during childhood to help with speech development.
How can Klinefelter syndrome be avoided?
Unfortunately, Klinefelter syndrome is a genetic condition that cannot be prevented. It's a random error in the genetic code that happens before birth. This condition is not passed down through a family (inherited) and there is nothing a parent can do to prevent their child from having Klinefelter syndrome.Jul 13, 2020
What causes Klinefelter?
Klinefelter syndrome can be caused by: One extra copy of the X chromosome in each cell (XXY), the most common cause. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms. More than one extra copy of the X chromosome, which is rare and results in a severe form.Sep 21, 2019
Why are Klinefelter males tall?
From early school age, boys with Klinefelter's syndrome tend to be taller (increased leg length) because testosterone normally stops boys growing after puberty. This increase in height is maintained throughout life. Patients with Klinefelter's syndrome may have reduced coordination compared with other boys.
Why are XXY men infertile?
Between 95% and 99% of XXY men are infertile because they do not produce enough sperm to fertilize an egg naturally. But, sperm are found in more than 50% of men with KS. 6
What is the procedure to remove breasts?
Some health care providers recommend surgery—called mastectomy (pronounced ma-STEK-tuh-mee )—to remove or reduce the breasts of XXY males. When adult men have breasts, they are at higher risk for breast cancer than other men and need to be checked for this condition regularly.
What can a counselor do for a boy with KS?
Mental health therapists or counselors help males with KS find ways to cope with feelings of sadness, depression, self-doubt, and low self-esteem. They can also help with substance abuse problems. These professionals can also help families deal with the emotions of having a son with KS.
What does a behavioral therapist do?
Behavioral therapist s help with specific social skills, such as asking other kids to play and starting conversations. They can also teach productive ways of handling frustration, shyness, anger, and other emotions that can arise from feeling "different.".
What is occupational therapy?
Occupational therapists help build skills needed for daily functioning, such as social and play skills, interaction and conversation skills, and job or career skills that match interests and abilities. Behavioral therapist s help with specific social skills, such as asking other kids to play and starting conversations.
Can XXY males take testosterone?
Not all males with XXY condition benefit from testosterone therapy. For males whose testosterone level is low to normal, the benefits of taking testosterone are less clear than for when testosterone is very low.
Is XXY the same as social behavior?
Many of the professionals and methods for treating learning and language symptoms of the XXY condition are similar to or the same as the ones used to address social and behavioral symptoms.
What is the best treatment for gynaecomastia?
For those with excess breast tissue (gynaecomastia), breast reduction surgery may be offered if this does not resolve with optimised testosterone therapy .
How to reduce low testosterone?
Healthy lifestyle changes such as stopping smoking, keeping alcohol intake within recommended limits , maintaining a well-balanced diet, maintaining a healthy weight, and taking part in regular exercise can improve symptoms of low testosterone and reduce the risk of developing KS-associated conditions.
Does TRT help with sperm production?
TRT does not improve sperm production and, if fertility is important, TRT should be delayed until after fertility issues have been addressed.
Does low testosterone cause osteoporosis in KS?
For KS patients, other than the risks of low testosterone, patients also have an increased risk of diabetes and osteoporosis (weak bones). There is also evidence that thrombo-embolic (abnormal blood clotting) events like deep vein thrombosis (DVT) are more common in KS.
Is there a cure for Klinefelter syndrome?
There is no cure for Klinefelter Syndrome (KS). However there are treatments available for the problems associated with the condition.
Can a man with KS be inherited?
The condition cannot be inherited by children of men with KS, even if assisted fertility techniques have been used.
What is the meaning of "nondisjunction" in Klinefelter syndrome?
Listen. Klinefelter syndrome usually occurs as a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes. For example, an egg or sperm cell may gain one or more extra copies of the X chromosome as a result ...
How many chromosomes does a male have?
Males normally have one X chromosome and one Y chromosome in each cell (46, XY), while females have two X chromosomes (46, XX). People with Klinefelter syndrome usually have two X chromosomes and one Y chromosome (47, XXY).
What is MedlinePlus Genetics?
MedlinePlus Genetics contains information on Klinefelter syndrome. This website is maintained by the National Library of Medicine.
How many chromosomes are in a child's chromosome?
[2] Most often, Klinefelter syndrome is caused by a single extra copy of the X chromosome, resulting in a total of 47 chromosomes per cell.
What is the 47 XXY form of Klinefelter?
Babies with the 47, XXY form of Klinefelter differ little from healthy children. The results of one study on non- mosaic XXY infants younger than 2 years indicated that most XXY babies had normal external genitalia and facial features with height and weight in the normal range.
What age do you get Klinefelter syndrome?
Women who have pregnancies after age 35 have a slightly increased chance of having offspring with this syndrome. [5] The features of Klinefelter syndrome are due to the extra copies of genes on the extra X chromosome, which can alter male sexual development.
How many babies have extra X chromosomes?
It is estimated that 1 in every 500 to 1,000 newborn males has an extra X chromosome, making Klinefelter syndrome one of the most common chromosomal disorders seen among newborns. Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns. [1] [7]#N#It is suspected that Klinefelter syndrome is underdiagnosed because mild cases may not be identified. In addition, the features of this condition vary and can overlap significantly with those of other conditions. [7]
What happens when an egg holds an X?
The egg holds an X. The sperm could have either an X or a Y chromosome. In a typical situation, if an X sperm meets an egg holding an X, the resulting baby will be a female (46, XX). If the sperm holds a Y chromosome when it meets the egg, the resulting baby will be a male (46, XY). Klinefelter syndrome happens when there is an extra X chromosome ...
What is the genetic condition where a male has an extra X chromosome?
Klinefelter Syndrome. Klinefelter syndrome is a common genetic where a male is born with an extra X chromosome. Typically, a male has one X and one Y chromosome. People with Klinefelter syndrome can experience breast growth, breast cancer, osteoporosis, infertility and learning difficulties. Treatment typically involves physical ...
Why do testicles fail in Klinefelter syndrome?
This happens because the testicles usually “fail” in Klinefelter syndrome, which makes them unable to make testosterone and sperm. Replacing the testosterone hormone can help minimize some of the symptoms of the condition. In children and teens testosterone is usually replaced via injection.
What are the conditions that are associated with Klinefelter syndrome?
These conditions include: Hypertension (high blood pressure).
How many copies of X chromosomes are there in a girl?
A typical girl has two copies of the X chromosome (46, XX). There are a number of different conditions where an individual may have more or less than the expected X or Y chromosomes. Klinefelter syndrome (KS) is a genetic condition where there’s an extra X chromosome present in a male’s genetic code. Instead of having a total of 46 chromosomes, ...
How many people with Klinefelter syndrome know about their diagnosis?
Some people believe that only 20 to 30% of all people with Klinefelter syndrome ever know about their diagnosis. For others, it’s only discovered when the man is tested for infertility. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission.
What are the physical symptoms of Klinefelter syndrome?
Physical symptoms of Klinefelter syndrome include: Being born with a smaller penis, and/or undescended testicle (s). Having abnormal body proportions. (This can include being too tall, having long legs and a short trunk and the shoulders being equal to hips in size rather than wider, which is more typical in a male.)
How many chromosomes does Klinefelter syndrome have?
Most males with Klinefelter syndrome, also called XXY males, have two X chromosomes instead of one. The extra X usually occurs in all body cells. Sometimes the extra X only occurs in some cells, resulting in a less severe form of the syndrome. This is called a mosaicism, and is very common.
What is the name of the condition where a male has at least one extra chromosome?
Klinefelter syndrome is a group of conditions that affects the health of males who are born with at least one extra X chromosome. Chromosomes, found in all body cells, contain genes. Genes provide specific instructions for body characteristics and functions. For example, some genes determine height and hair color. Other genes influence language skills and reproductive functions. Each person typically has 23 pairs of chromosomes. One of these pairs (sex chromosomes) determines a person’s sex. A baby with two X chromosomes (XX) is female. A baby with one X chromosome and one Y chromosome (XY) is male.
What kind of doctor treats Klinefelter syndrome?
Males with Klinefelter syndrome should be seen by a team of health care providers. The team may include endocrinologists, general practitioners, pediatricians, urologists, speech therapists, genetic counselors, and psychologists. Surgery may be needed to reduce breast size.
How many chromosomes are there in a human?
Each person typically has 23 pairs of chromosomes. One of these pairs (sex chromosomes) determines a person’s sex. A baby with two X chromosomes (XX) is female. A baby with one X chromosome and one Y chromosome (XY) is male. Most males with Klinefelter syndrome, also called XXY males, have two X chromosomes instead of one.
What are the health problems associated with Klinefelter syndrome?
Klinefelter syndrome can lead to weak bones (osteoporosis), varicose veins, and autoimmune diseases (when the immune system acts against the body), such as lupus or rheumatoid arthritis.
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What is the most common cause of Klinefelter syndrome?
Klinefelter syndrome can be caused by: One extra copy of the X chromosome in each cell (XXY), the most common cause. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms. More than one extra copy of the X chromosome, which is rare and results in a severe form. Extra copies of genes on the X chromosome can ...
What is the genetic condition that results when a boy is born with an extra copy of the X chromos
Klinefelter syndrome is a genetic condition that results when a boy is born with an extra copy of the X chromosome. Klinefelter syndrome is a genetic condition affecting males, and it often isn't diagnosed until adulthood.
What are the characteristics of a boy after puberty?
Longer legs, shorter torso and broader hips compared with other boys. Absent, delayed or incomplete puberty. After puberty, less muscle and less facial and body hair compared with other teens. Small, firm testicles.
What are the signs of a baby's scrotum?
Babies. Signs and symptoms may include: Weak muscles. Slow motor development — taking longer than average to sit up, crawl and walk. Delay in speaking. Problems at birth, such as testicles that haven't descended into the scrotum.
Is Klinefelter syndrome related to hypogonadism?
Autism spectrum disorder. A number of complications caused by Klinefelter syndrome are related to low testosterone (hypogonadism). Testosterone replacement therapy reduces the risk of certain health problems, especially when therapy is started at the beginning of puberty. By Mayo Clinic Staff.
What are the diseases that affect the heart?
Heart and blood vessel disease. Breast cancer and certain other cancers. Lung disease. Metabolic syndrome, which includes type 2 diabetes, high blood pressure (hypertension), and high cholesterol and triglycerides (hyperlipidemia) Autoimmune disorders such as lupus and rheumatoid arthritis.
Can men with Klinefelter syndrome have children?
The effects of Klinefelter syndrome vary, and not everyone has the same signs and symptoms. Most men with Klinefelter syndrome produce little or no sperm, but assisted reproductive procedures may make it possible for some men with Klinefelter syndrome to father children.
