Treatment FAQ

what is the sequence of operations during ivf treatment?

by Prof. Horacio Wisoky DDS Published 2 years ago Updated 2 years ago

IVF involves several steps — ovarian stimulation, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVF can take about two to three weeks, and more than one cycle may be required.

The process involves fertilising the egg with the sperm in an incubator outside the body, then transferring the best embryo back into the woman's uterus. The whole process, up to the embryo transfer stage, usually takes three to four weeks.May 17, 2017

Full Answer

What is the IVF process?

IVF has been around for decades and you most likely already know the basic idea behind IVF: uniting egg and sperm outside the body in a culture. But there's so much more to IVF that happens before and after that. Here's a closer look at the IVF process in five steps.

What are the different parts of IVF treatment?

To sum up, in the words of Dr. Gorka Barrenetxea, an IVF treatment involves four major parts: Briefly, an IVF treatment has 4 steps. The first one is the ovarian stimulation; the second one is follicular puncture; the third one is the IVF procedure itself; and the fourth and last one is the embryo transferinto the uterus.

What is the next step in my IVF treatment?

The next step in your IVF treatment is triggering the oocytes to go through the last stage of maturation. The eggs must complete their growth and development before they can be retrieved. This last growth is triggered with human chorionic gonadotropin (hCG). Brand names for this include Ovidrel, Novarel, and Pregnyl.

What happens on the first day of my IVF treatment cycle?

The first official day of your IVF treatment cycle is Day 1 of your period. Everyone’s body is different; your fertility nurse will help you understand how to identify Day 1. The stimulation phase begins on Day 1. In a natural monthly cycle, your ovaries would normally produce one egg.

What is IVF procedure step by step?

Step-by-Step Descriptions of the IVF ProceduresStep 1: Control Ovarian Hyperstimulation (COH) ... Step 2: Egg Retrieval. ... Step 3: Fertilization and Embryo Culture. ... Step 4: Embryo Quality. ... Step 5: Embryo Transfer. ... Laser Assisted Hatching. ... Cryopreservation.More items...

What is the correct sequence of events in IVF?

What are the basic steps involved in IVF treatment cycle. Given below are events that lead to pregnancy and development of embryo
(i) Fertilization of egg
(ii) Maturation of egg
(iii) Release of egg
(iv) Embedding of embryo in thickened uterine wall.

What are the four steps of IVF?

IVF is a four stage processIVF is a four-stage process.Stage 1: Ovarian stimulation, monitoring, and ovulation triggering. Having a greater number of mature eggs available for fertilisation increases the chances. ... Stage 2: Egg retrieval (Egg Pick Up [EPU]) ... Stage 3: Fertilisation. ... Stage 4: Embryo.

How many rounds are in IVF?

A full cycle of IVF treatment covers ovarian stimulation and egg recovery, insemination, and embryo replacement.

What are the 5 stages of IVF?

IVF involves several steps — ovarian stimulation, egg retrieval, sperm retrieval, fertilization and embryo transfer.

How many injections do you need for IVF treatment?

Depending on the course of specific treatment and cycle, a patient may receive up to 90 shots per cycle with a frequency of 1–2 injections per day.

How many days after period do you start IVF injections?

An IVF treatment cycle begins on Day 1 of your period, and ends with your pregnancy blood test roughly four weeks later.

How many scans do you get during IVF?

No matter what treatment protocol you are on you will need to have about 3 or 4 ultrasound scans from day 5 of the cycle to assess the growth of your follicles and assess whether the endometrium is thickening up.

How long is an IVF cycle from start to finish?

The IVF cycle itself takes around four weeks, the length of a normal ovulation cycle. Treatment begins only after initial fertility testing is completed. Fertility testing often includes assessing your ovarian reserve or egg quality, uterine cavity evaluation, and semen analysis.

Which round of IVF is most successful?

The Greatest Percentage of IVF Success Occurs in Six CyclesWomen under the age of 35 are the most likely to benefit from a six-cycle regimen.Women 40-42 (using their own eggs) had a 31.5% live birth rate at the six-cycle mark.Women older than 42 (using their own eggs) had a <4% live birth rate at the six-cycle mark.More items...•

Is IVF procedure painful?

It is similar to a vaginal ultrasound appointment or even a pap smear. In this procedure, one or more embryos are transferred to the uterus using ultrasound guidance and an embryo transfer catheter. You will be able to see the entire procedure take place on an ultrasound screen. This process is not painful.

What is 3rd cycle IVF?

With our 3-cycle Natural IVF package, we provide you with 3 cycles of Natural IVF. Eggs are collected from 3 consecutive cycles and fertilised; the best quality embryo/s will then be transferred in a final procedure and any spare embryos can be frozen and stored for later use.

Why do women get IVF?

The woman is given injection hormones to stimulate healthy egg development. IVF helps her produce more eggs than she would in a normal month.

How are eggs and sperm combined?

The egg and sperm are then combined in a lab through varying technologies of fertilization, such as intracytoplasmic sperm injection (ICSI).

How is an embryo transferred?

During an embryo transfer, a woman’s uterus is watched by ultrasound and a small catheter is placed into the uterine cavity through the cervix. The embryo (s) are then placed in the uterus. Ten days later, the woman returns to the clinic for a blood test to determine if she’s pregnant.

How many couples have difficulty conceiving?

In fact, approximately one in eight couples who attempt pregnancy has difficulty conceiving a child. With the help of modern fertility treatment, particularly in vitro fertilization (IVF), couples are realizing their dreams of becoming parents.

How are eggs collected from the ovaries?

Eggs are then collected from the ovaries via a minor surgery during which the woman is sedated and the eggs are retrieved trans-vaginally. “We use a small needle guide to pass a needle over a trans-vaginal ultrasound to remove fluid from the follicles,” she explains.

Is IVF a process?

“ Going through IVF is a process that we endure together,” says Dr. Brahma. “A really exciting moment is getting to make a phone call to a patient giving her the great news that it has worked and her pregnancy test is positive. It’s one of the most exciting phone calls I get to make.”

How long does it take to get a baby from IVF?

There are, of course, a myriad of steps that comprise that “straightforward” procedure and when all is said and done, the average IVF cycle takes around four to six weeks, depending on how things progress.

When do you get tested for pregnancy after embryo transfer?

You will be tested for pregnancy at days 9 and 12 after the transfer to see if the embryo has implanted. During this time, you will use a progesterone suppository (the first of which was administered after the embryo transfer). If you are pregnant (hurray!), it is recommended that you continue using the progesterone supplements throughout the first trimester.

How long does it take for an embryo to mature?

Step 4. Your eggs will be fertilized within hours of their retrieval. It takes three days for embryos to mature to the point that they can be tested for genetic viability and/or gender testing. The results of these tests are available between 24 and 48 hours afterwards. If there is a viable embryo, you will be scheduled for your exciting embryo transfer.

Do you need sperm to fertilize eggs?

If you are using your partner’s sperm, he will have either already provided a sperm sample the day or two before, or may be scheduled to do so the same day as your eggs are retrieved.

When does IVF start?

We describe an IVF ‘cycle’ as one round of IVF treatment. The cycle starts on Day 1 of your period and ends with your pregnancy blood test. Depending on your treatment plan, your fertility specialist may recommend that you start medication or injections before the first day of your cycle.

What is the first day of IVF?

The first official day of your IVF treatment cycle is Day 1 of your period. Everyone’s body is different; your fertility nurse will help you understand how to identify Day 1. Your step-by-step guide to an IVF cycle. Step 2: Stimulating your ovaries. The stimulation phase begins on Day 1.

What is the method of insemination?

Another method of insemination is for our scientists to hand select a single “ideal” sperm to inject directly into each individual egg known as ICSI. The method of fertilisation will be directed by your specialist in discussion with your situation to optimise your fertilisation and pregnancy chances in each cycle.

How many eggs do you produce in an IVF cycle?

Step 2: Stimulating your ovaries. The stimulation phase begins on Day 1. In a natural monthly cycle, your ovaries would normally produce one egg. With an IVF cycle, you’ll take medication for eight to 14 days to encourage the follicles in your ovaries (where the eggs grow) to produce more eggs. Your specialist will prescribe medication specific ...

How is sperm graded?

We grade the sperm using four different levels of quality. The laboratory will prepare the samples to collect the most viable sperm from the sample for combining with your eggs, all so our scientists can spot the best sperm under powerful microscopes. We take great care in preparing the sperm prior to introduction to the eggs with multiple methods at our disposals tailored to each patients sample. The ideal sperm is not too fat or too thin, with a tail that’s not too long or too short and is referred to as having normal morphology (shape/structure). Being able to identify morphologically normal sperm is a skill that our scientists develop over many years, with constant fine tuning, to select the ideal sperm for every egg. Once the sample is prepared we have it ready and we have it ready and waiting in the lab for the next step We then introduce the prepared sperm to the eggs collected in your egg pick up.

What hormones are used to stimulate ovaries?

follicle-stimulating hormone (FSH) luteinizing hormone (LH) Throughout your cycle, your specialist and fertility nursing team keep a close eye on your ovaries and how the follicles are developing with blood tests and ultrasounds. They’ll adjust your medication if needed.

How many eggs are collected during a fertility test?

The average number of eggs collected is eight-15, however this is also dependant on your age and clinical history.

What is IVF treatment?

In vitro fertilization (IVF) is a treatment for infertility or genetic problems. If IVF is performed to treat infertility, you and your partner might be able to try less-invasive treatment options before attempting IVF, including fertility drugs to increase production of eggs or intrauterine insemination — a procedure in which sperm are placed directly in the uterus near the time of ovulation.

How long does it take to get an IVF?

One cycle of IVF can take about two to three weeks. More than one cycle may be needed.

What causes fewer eggs to be fertilized?

Fallopian tube damage or blockage makes it difficult for an egg to be fertilized or for an embryo to travel to the uterus. Ovulation disorders. If ovulation is infrequent or absent, fewer eggs are available for fertilization. Endometriosis.

How are eggs removed during in vitro fertilization?

During in vitro fertilization, eggs are removed from mature follicles within an ovary (A). An egg is fertilized by injecting a single sperm into the egg or mixing the egg with sperm in a petri dish (B). The fertilized egg (embryo) is transferred into the uterus (C).

How many cells are in an embryo after fertilization?

Three days after fertilization, a normally developing embryo will contain about six to 10 cells. By the fifth or sixth day, the fertilized egg is known as a blastocyst — a rapidly dividing ball of cells. The inner group of cells will become the embryo. The outer group will become the cells that nourish and protect it.

Why do IVF cycles have multiple eggs?

Multiple eggs are needed because some eggs won't fertilize or develop normally after fertilization.

What is the purpose of in vitro fertilization?

In vitro fertilization (IVF) is a complex series of procedures used to help with fertility or prevent genetic problems and assist with the conception of a child.

What are the steps of IVF?

A Step-By-Step Look at the IVF Process 1 Older women with fertility issues 2 Women with damaged or blocked fallopian tubes 3 Women with endometriosis 4 Male infertility caused by low sperm count or blockage

What is the next step after IVF?

The IVF process basically replicates natural reproduction. The next step after the IVF process determines whether the procedure worked — the pregnancy test.

What is IVF used for?

IVF is commonly used to treat: Older women with fertility issues. Women with damaged or blocked fallopian tubes. Women with endometriosis. Male infertility caused by low sperm count or blockage.

Why do IVF women have multiple embryos?

Sometimes more than one embryo ends up implanting, which is why multiples are common in women who use IVF. The IVF process basically replicates natural reproduction.

What happens after you collect eggs?

This one is meant to prep the lining of your uterus to receive the embryos that will be transferred back into you.

How does a sexectomy procedure work?

During the procedure, your doctor will use an ultrasound to guide a thin needle into each of your ovaries through your vagina. The needle has a device attached to it that suctions the eggs out one at a time.

How long does it take for sperm to fertilize an egg?

It usually takes a few hours for a sperm to fertilize an egg. Your doctor may also inject the sperm directly into the egg instead, a process known as intracytoplasmic sperm injection (ICSI). If playback doesn't begin shortly, try restarting your device. Full screen is unavailable. Learn More.

What is IVF in medical terms?

The medical term "In Vitro" Fertilization, abbreviated as IVF, literally means to fuse the gametes (egg and sperm) together in the laboratory. Since this union is done artificially, imitating the natural process, a series of technical steps are required, as one shall see in the following sections. In the meantime, you can find a brief summary ...

How many embryos are transferred in IVF?

Embryo cryopreservation. Normally, a single embryo is transferred per IVF cycle, although in some cases two or even three embryos are transferred. Embryos of good quality that are not used for the ET procedure are cryopreserved via a technique known as embryo vitrification.

How much does IVF cost?

The price of in vitro fertilization varies by country. In the United States, IVF packages using own eggs start from $8,500.

What is the role of embryologists?

The role of the embryologist is to just put the eggs and sperm in the culture plate. The sperms are expected to be capable of penetrating the egg cell by themselves.

What is the process of insemination and fertilization?

Egg insemination & fertilization. This step involves fusing together the egg and sperm cells to mix the DNAs of both parents, giving raise to a new being. The extent to which the embryologist is involved in this process varies on a case-by-case basis.

How is egg retrieval done?

Egg retrieval is done via a procedure known as follicular puncture or ovum pick-up (OPU). It is the next step when the oocytes are mature and ready to be harvested. This surgical procedure is performed under anesthesia, and requires an OB/GYN to puncture the ovarian follicles (small "sacs" that contain the eggs), and aspirate their content at the same time. Then, the liquid aspirated is evaluated at the lab in order to collect the eggs.

How long does the ovary procedure last?

The procedure lasts about 30 minutes. Further reading: Ovum Pick-Up Procedure: How Are Eggs Harvested in IVF?

What time does a patient receive a fertilization report?

The call will come approximately between the hours of 9:00 AM to 3:00 PM. The patient will also be able to ask questions regarding the cycle.

How long does it take to transfer an embryo?

Overall, the transfer procedure will take approximately 20 minutes. The patient will then return to their private room and rest for 20 minutes prior to leaving the facility.

When do embryos freeze?

The remaining embryos left in culture will be allowed to develop into viable, freeze quality Blastocysts until the end of day 6. In order to be considered viable on day 6 and day 7, the embryo must reach a Blastocyst stage. Any embryos that do not reach a Blastocyst stage will be discarded on day 6 due to poor embryo development.

Overview

Why It's Done

Risks

  • Risks of IVFinclude: 1. Multiple births. IVFincreases the risk of multiple births if more than one embryo is transferred to your uterus. A pregnancy with multiple fetuses carries a higher risk of early labor and low birth weight than pregnancy with a single fetus does. 2. Premature delivery and low birth weight. Research suggests that IVFslightly increases the risk that the baby will be …
See more on mayoclinic.org

How You Prepare

  • The Centers for Disease Control and Prevention and the Society for Assisted Reproductive Technology provide information online about U.S. clinics' individual pregnancy and live birth rates. A clinic's success rate depends on many factors. These include patients' ages and medical issues, as well as the clinic's treatment population and treatment approaches. Ask for detailed informati…
See more on mayoclinic.org

What You Can Expect

  • IVF involves several steps — ovarian stimulation, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVFcan take about two to three weeks. More than one cycle may be needed.
See more on mayoclinic.org

Results

  • About 12 days to two weeks after egg retrieval, your doctor will test a sample of your blood to detect whether you're pregnant. 1. If you're pregnant,your doctor will refer you to an obstetrician or other pregnancy specialist for prenatal care. 2. If you're not pregnant, you'll stop taking progesterone and likely get your period within a week. If you don't get your period or you have un…
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Clinical Trials

  • Explore Mayo Clinic studiesof tests and procedures to help prevent, detect, treat or manage conditions.
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