Treatment FAQ

what is the rate of weight gain on lupron treatment with add back therapy

by Prof. Sadye Langworth Published 3 years ago Updated 2 years ago

Full Answer

What is add-back therapy for Lupron side effects?

To reduce risk of Lupron’s side effects, your doctor may prescribe progestin “add-back” therapy. This is a pill taken daily to help manage some side effects without affecting Lupron’s efficacy. Not everyone on Lupron should try add-back therapy.

Does Lupron stop working after extended ADG therapy?

The evidence suggests that it won't after extended ADG therapy — or won't to a significant degree. While this may not be a concern for you, it can be a concern for many. I have been on Lupron for 2 years and recently had another 6 month injection.

How is Lupron administered for hormone replacement therapy?

Doctors often prescribe hormone therapies in combination with radiation therapy or following surgery. They administer Lupron by injecting it under a person’s skin, which they will do between once a month and once every 6 months. Because Lupron lowers testosterone levels, it can cause a range of side effects.

How long should you take Lupron for?

Doctors discovered that women taking Lupron decreased signs and symptoms for patients with endometriosis after monthly treatment when taken for 6 months. Additionally, Lupron has been found to reduce pain during sexual intercourse when taken for at least 6 months.

Does Lupron injections cause weight gain?

Weight gain or weight loss Weight changes may occur with Lupron Depot use. One of the most common side effects of women taking Lupron Depot is weight gain.

Does Lupron cause water retention?

Possible but rare side effects include nausea and/or vomiting. Eat a light snack if you experience nausea. If these effects persist or are severe, contact your doctor. You may also experience swelling of hands, feet or lower legs (fluid retention).

Does Lupron affect appetite?

painful or difficult urination; or. high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor.

Will Lupron side effects go away?

Lupron Depot side effects are almost always reversible and will go away after treatment is complete.

Does Lupron make you tired?

Share on Pinterest Side effects of Lupron can include hot flashes, depression, and fatigue.

Can you drink alcohol while on Lupron?

Both Lupron and alcohol can cause upset stomach, nausea, and dizziness. Drinking alcohol while using Lupron may worsen these effects. Avoid or limit drinking alcohol while taking Lupron.

Does Lupron make you angry?

Under ADVERSE REACTIONS: ‒ New section was added under Postmarketing reports of Psychiatric Disorders: Emotional symptoms, such as crying, restlessness (impatience), anger, and acting aggressive have been observed with GnRH agonists, including LUPRON DEPOT-PED; Depression, including rare reports of suicidal ideation ...

When do Lupron side effects begin?

Most of the time, this has happened within 2 weeks after the first dose. Call your doctor right away if you have a sudden headache, throwing up, passing out, mood changes, eye weakness, not able to move your eyes, or change in eyesight. This drug may cause weak bones. This may happen more often if used for a long time.

How common are Lupron side effects?

In clinical trials, the most common side effects of LUPRON DEPOT, occurring in >10% of patients, include hot flashes/sweats, headache/migraine, decreased libido, depression/emotional lability, dizziness, nausea/vomiting, pain, vaginitis, and weight gain.

Do Lupron side effects get worse?

During the first few weeks of treatment, your hormone levels will actually go up before they go down. This is a normal response to this medication. Your symptoms may get worse for a few weeks.

What are the long term effects of taking Lupron?

Those reports frequently note injection-site pain but also include dozens of cases of bone problems, such as pain or disorders, and the inability to walk. Among men who take Lupron, its label warns of increased risk of heart attacks, strokes and sudden death.

What are the long term side effects of Lupron Depot?

The most common side effects were those commonly associated with low estrogen states, including hot flashes/sweating, weight gain, mood swings/irritability, and breast changes/tenderness/pain, as well as reaction/pain at the injection site (Table 3).

How long should you take Lupron for prostate cancer?

Patients treated with Lupron Depot (leuprolide acetate) for prostate cancer usually continue treatment upon development of castration-resistant pro...

Is Lupron Depot a chemotherapy treatment?

Lupron Depot (leuprolide acetate) injection is not a chemotherapy treatment, but a prescription hormone medicine used in the palliative treatment o...

How do you inject Lupron Depot for prostate cancer?

Lupron Depot (leuprolide acetate) is a depot suspension formulation only injected by your doctor. Lupron Depot is injected into a muscle of your up...

Does Lupron Depot need to be refrigerated?

Before reconstitution, Lupron Depot for treatment of prostate cancer can be stored in its original container at room temperature (77°F [25°C]), wit...

Will I get my period while on Lupron?

In clinical studies evaluating endometriosis, 95% of women started their periods (normal menstrual cycle) in the third month after treatment ended...

What does Lupron do for IVF?

During an vitro fertilization (IVF) protocol, your doctor may use leuprolide (Lupron) injection as part of an ovarian stimulation regimen. Leuproli...

Are Lupron Depot and Eligard the same drug?

Lupron Depot and Eligard are brand name medicines that both contain the active ingredient leuprolide acetate. Both Lupron Depot and Eligard are pre...

How can hormone therapy help with prostate cancer?

For people with prostate cancer, the aim of hormone therapy is to reduce testosterone levels in the body. Male hormones, such as testosterone, encourage the growth of prostate cancer cells. Therefore, lowering testosterone levels in the body can help slow the progression of prostate cancer. Doctors typically prescribe hormone therapy ...

What is luporn used for?

Lupron is a type of hormone therapy for prostate cancer. It works by lowering the amount of testosterone in a person’s body, which helps slow the growth of cancer cells.

What is the treatment for prostate cancer?

There are several treatment options for prostate cancer, including other LHRH agonists and various types of hormone therapy.

What is the name of the drug that doctors use to treat prostate cancer?

Alternative treatment. Outlook. Summary. Lupron is the brand name for leuprolide acetate. This drug is a type of hormone therapy that doctors typically use in combination with other treatments to treat people with prostate cancer.

Can you take Lupron with prostate cancer?

Hormone therapies, such as Lupron, are often effective in combination with other treatments for people with late-stage prostate cancer. Many doctors do not recommend hormone therapy during the early stages of this disease.

Does luporn help with prostate cancer?

Lupron is one of several drugs that doctors may prescribe to help fight prostate cancer by reducing testosterone levels in the body. In this article, we explore how Lupron works, how effective it is, and what to expect during treatment. We also discuss testosterone flares, side effects, and the outlook for people with prostate cancer.

Does luporn lower testosterone?

Because Lupron lowers testosterone levels, it can cause a range of side effects. Anyone experiencing severe or concerning symptoms may wish to discuss these with their doctor.

How often is luporn depot injected?

Lupron Depot is injected under the skin or into a muscle, once every month or once every 3 to 6 months.

How long does it take for leuprolide to get worse?

Keep using the medicine as directed, and tell your doctor if your condition is still worse after 2 months of using Lupron Depot. You may need frequent medical tests while using Lupron Depot.

What is luporn depot used for?

Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids.

How to store luporn?

Store Lupron Depot in the original carton at room temperature, away from moisture and heat. Protect from light.

Does leuprolide reduce testosterone?

Lupron Depot ( leuprolide) overstimulates the body's own production of certain hormones, which causes that production to shut down temporarily. This medicine reduces the amount of testosterone in men or estrogen in women.

Can luporn cause birth defects?

Your symptoms may become temporarily worse when you first start using Lupron Depot. Tell your doctor if this continues for longer than 2 months. Call your doctor at once if you have a seizure, or unusual changes in mood or behavior. Lupron Depot can harm an unborn baby or cause birth defects.

Can you take luporn if you are pregnant?

Lupron Depot can cause birth defects. Do not use if you are pregnant.

What to know before taking leuprolide?

Before using leuprolide, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

How does leuprolide work?

It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult ...

How long does it take for leuprolide to stop bleeding?

In girls, when this medication is used regularly, it is expected that the menstrual period will stop or decrease to light bleeding/spotting during the first 2 months. Tell the doctor promptly if regular periods continue after 2 months of treatment with leuprolide.

How long does it take for a pituitary apoplexy to occur?

Rarely, a very serious problem with your pituitary gland (pituitary apoplexy) may occur, usually in the first hour to 2 weeks after the first injection. Get medical help right away if any of these very serious side effects occur: sudden severe headache, sudden severe mental/mood changes (such as severe confusion, difficulty concentrating), ...

Does leuprolide help with bone growth?

It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes ( estrogen in girls, testosterone in boys).

Can leuprolide cause allergies?

Before using leuprolide, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as histrelin, triptorelin); or of any other allergies. This product may contain inactive ingredients (such as benzyl alcohol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Can leuprolide cause QT prolongation?

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using leuprolide, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

How often is luporn injected?

Lupron Depot is a prescription medication that is injected into the body every month or every 3 months to help reduce endometriosis pain and complications. Lupron was originally developed as a treatment for those with advanced prostate cancer, but it’s become a very common and usually effective treatment for endometriosis.

How does luporn work?

Lupron works by reducing the overall levels of estrogen in the body. Estrogen is what causes the tissues inside the uterus to grow.

How long does it take for estrogen to decrease after ovulation?

After a few weeks, your estrogen levels will decrease, stopping ovulation and your period. At this point, you should experience relief from your endometriosis pain and symptoms.

What is luporn depot?

Lupron Depot is a prescription medication ...

Does Lupron help with endometriosis?

Lupron has been found to reduce endometrial pain in the pelvis and abdomen. It’s been prescribed to treat endometriosis since 1990. Doctors discovered that women taking Lupron decreased signs and symptoms for patients with endometriosis after monthly treatment when taken for 6 months.

Can you get pregnant with luporn?

Without protection, you may become pregnant on Lupron. To avoid drug interactions and potential pregnancy, use nonhormonal methods of birth control such as condoms, a diaphragm, or a copper IUD. Lupron is commonly used during fertility treatments such as in vitro fertilization (IVF). Your doctor may have you take it to prevent ovulation ...

Does Lupron protect you from pregnancy?

Additionally, Lupron doesn’t protect you from pregnancy. Contact your doctor right away if you know or think you’re pregnant.

What are the side effects of Lupron?

Other potential side effects of Lupron can include: skin reaction at the injection site. shrunken testicles. hot flashes. mood swings. breast tenderness or growth of breast tissue. erectile dysfunction or loss of sex drive. osteoporosis. loss of muscle mass.

How is luporn administered?

Lupron is administered by injection. The dosage will vary according to your particular situation. Here are some typical dosage options your doctor may prescribe:

What is luprolide acetate?

Lupron is a brand name for leuprolide acetate, a luteinizing hormone-releasing hormone (LHRH) agonist. LHRH is a naturally occurring hormone that stimulates the production of testosterone in the testes. Lupron effectively blocks LHRH, so it reduces the amount of testosterone in your body. Lupron is a type of hormone therapy used to treat prostate ...

What does it mean when your prostate antigen is on the rise?

Periodic blood tests can track rising or falling PSA levels. PSA levels on the rise would indicate that hormone treatment isn’t working.

What is the best treatment for prostate cancer?

Learn more about other prostate cancer drugs. Your doctor may also recommend surgery, radiation, or chemotherapy. In some cases where hormone treatment is no longer effective, a cancer vaccine can help prompt your immune system to attack cancer cells. Ask your doctor if this is an option for you.

How long does luporn last?

This can make symptoms of advanced prostate cancer worse, but it should last for only a few weeks. Depending on where your tumors are located, these symptoms could include: bone pain. problems with urination.

How long does testosterone treatment last?

There’s no way to know for certain how long the treatment will continue to work. It could be anywhere from a few months to a few years.

Close to divorce after prostatectomy

I am in shock and am grieving what I think is coming soon. My husband had a radical prostatectomy a year ago, one nerve spared, the cancer had left the capsule. He is young (52), and so far, his PSA has been 0 (checked four times a year). When he had the surgery, he developed an infection and had a terrible reaction to cipro.

Is there any chance of a sex life when taking Lupron

Hi All, It looks like I will be going on a six month course of Lupron and I am wondering what this does to your sex life. I believe your libido no longer exists so you have no desire, but what happens if you try to have an orgasm whilst on this drug.

Orgasm after prostatectomy - time for honesty!

Hey guys, I've been thinking about writing this post for quite some time now. In fact about 29 months since my nerve-sparing robotic surgery. It seems the thing that no one wants to talk about honestly- so here goes. Yes we all know that, despite no ejaculation, some of us (maybe nearly all of us) can still get an orgasm.

ANY thoughts: use of Ivermectin for prostate cancer in the lungs?

Prostate cancer nodules just in the lungs. PSA controlled by Bicalutamide at 0.6 BUT, would like to see the cancer gone! Are there any thoughts on use of Ivermectin (Stromectol) tablets? 12mg per day till cancer is gone? Thanks for your thoughts. Sign up to continue reading

What are the side effects of Lupron Depot?

You may experience side effects with Lupron Depot treatment such as: problems with your joints, digestive tract or breathing.

Where is luporn given?

Lupron Depot is given as an intramuscular (IM) injection into the muscle in your upper arm, buttock or thigh. Lupron Depot is available as single dose kits that contain a prefilled injection syringe of:

What happens if you stop luporn?

What happens if I stop Lupron Depot? If Lupron treatment is stopped, testosterone levels can rise and your cancer may worsen. Do not discontinue Lupron Depot unless your doctor tells you to stop treatment. In men, testosterone is reduced to castrate concentrations with Lupron Depot treatment.

Can Lupron be used for prostate cancer?

Can Lupron be used intermittently for prostate cancer? The use of intermittent androgen deprivation therapy (intermittent ADT) for prostate cancer is controversial , and studies have found differing results.

Is intermittent ADT better than continuous ADT?

A large review of clinical studies (a meta-analysis) that compared intermittent and continuous ADT in patients with either metastatic or recurrent prostate cancer found that intermittent ADT improved some physical and sexual side effects and was not worse than continuous treatment with respect to overall survival.

Is ADT better than continuous therapy?

One study of intermittent versus continuous ADT in men with metastatic hormone-sensitive prostate cancer showed that intermittent ADT was not better than continuous therapy and might increase the risk of death.

Is luporn a slow release?

Lupron Depot is a slow-release (depot) injection and must be administered in your doctor’s office each time you receive it. Lupron Depot is a gonadotropin releasing hormone (GnRH) agonist hormone therapy approved by the FDA for the palliative treatment (to relieve pain and other symptoms) of advanced prostate cancer.

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