Treatment FAQ

what is the prognosis for atherosclerosis with and without treatment

by Oral Harris Published 2 years ago Updated 1 year ago
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Medication

The coronary arteries are not seen during an echocardiogram, so unless a heart attack has already affected the heart, the presence of blockages cannot be made or excluded based upon this test ...

Procedures

Some people who have atherosclerosis have no signs or symptoms. They may not be diagnosed until after a heart attack or stroke. The main treatment for atherosclerosis is lifestyle changes. You also may need medicines and medical procedures. These treatments, along with ongoing medical care, can help you live a healthier life. Outlook

Self-care

Pathogenesis of Atherosclerosis

  • Roles of inflammation, endothelial perturbation and lipids. ...
  • Inflammation and chronic endothelial injury. ...
  • Molecular targeting to address chronic inflammation. ...
  • The role of lipid. ...
  • Evolution of the atherosclerotic plaque. ...
  • Damage to the vessel wall. ...
  • Platelet activation. ...

Nutrition

  • Numbness
  • Pain, especially during movement (known as claudication)
  • Signs of infection (2,3)

Can ECG show if someone has atherosclerosis?

What is the diagnosis and treatment of atherosclerosis?

What's the first step of the pathogenesis of atherosclerosis?

What are the signs and symptoms of atherosclerosis?

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What is the prognosis for atherosclerosis?

Outlook / Prognosis With early diagnosis and treatment, people with atherosclerosis can live healthy, active lives. But the disease can cause health emergencies and even death. That's why it's important to know your risk factors and work with your healthcare provider to reduce your risks.

What happens if atherosclerosis is not treated?

It can result in a shortage of blood and oxygen in various tissues of your body. Pieces of plaque can also break off, causing a blood clot. Without treatment, atherosclerosis can lead to heart attack, stroke, or heart failure, among other conditions.

What could happen to a patient with atherosclerosis?

When atherosclerosis narrows the arteries close to your heart, you may develop coronary artery disease, which can cause chest pain (angina), a heart attack or heart failure.

Can you live a full life with atherosclerosis?

Living healthy with atherosclerosis is possible with proper management, so take steps toward better heart health now. Atherosclerosis doesn't have to be a losing battle. In fact, the disease can be reversed through lifestyle changes, according to the American College of Cardiology.

What are the 4 stages of atherosclerosis?

Atherogenesis can be divided into five key steps, which are 1) endothelial dysfunction, 2) formation of lipid layer or fatty streak within the intima, 3) migration of leukocytes and smooth muscle cells into the vessel wall, 4) foam cell formation and 5) degradation of extracellular matrix.

Can atherosclerosis be fatal?

If a plaque bursts, a blood clot may form that may block the artery completely or travel to other parts of the body. Blockages, either complete or incomplete, can cause complications, including heart attack, stroke, vascular dementia, erectile dysfunction, or limb loss. Atherosclerosis can cause death and disability.

What is mild atherosclerosis?

Atherosclerosis thickening or hardening of the arteries. It is caused by a buildup of plaque in the inner lining of an artery. Plaque is made up of deposits of fatty substances, cholesterol, cellular waste products, calcium, and fibrin. As it builds up in the arteries, the artery walls become thickened and stiff.

What is the best treatment for atherosclerosis?

Lifestyle changes, such as eating a healthy diet and exercising, are the first treatment for atherosclerosis — and may be all that you need to treat your atherosclerosis....Surgery or other proceduresAngioplasty and stent placement. ... Endarterectomy. ... Fibrinolytic therapy. ... Coronary artery bypass surgery.

Can you live with blocked arteries?

Coronary Artery Disease (CAD) is treatable, but there is no cure. This means that once diagnosed with CAD, you have to learn to live with it for the rest of your life. By lowering your risk factors and losing your fears, you can live a full life despite CAD.

Can you get rid of atherosclerosis?

There are no proven cures for atherosclerosis. But medication and lifestyle changes can reduce the risk of complications.

How long does it take for atherosclerosis to develop?

Although atherosclerosis is believed to progress over many years, it has been increasingly noted to progress over few months to 2-3 years in few patients without traditional factors for accelerated atherosclerosis.

When does atherosclerosis normally begin during a person's life?

"Atherosclerosis usually starts in the teens and 20s, and by the 30s we can see changes in most people," says cardiologist Matthew Sorrentino MD, a professor at The University of Chicago Medicine. In the early stages, your heart-related screening tests, like cholesterol checks, might still come back normal.

How to reduce risk of atherosclerosis?

Lose extra pounds and maintain a healthy weight. If you're overweight, losing even just a few pounds can reduce your risk of high blood pressure and high cholesterol, two of the major risk factors for developing atherosclerosis. Ask your doctor what your target weight should be. Eat healthy foods.

How to tell if you have atherosclerosis?

This test can tell if you have atherosclerosis in the arteries in your legs and feet. During an ABI test, your doctor compares the blood pressure in your ankle with the blood pressure in your arm. An abnormal difference may be a sign of peripheral vascular disease, which is usually caused by atherosclerosis.

How to reduce the risk of heart disease?

Regular exercise improves blood flow, lowers blood pressure, and reduces your risk of conditions that increase the risk of atherosclerosis and heart disease. Aim to exercise at least 30 minutes most days of the week. If you can't fit it all into one session, try breaking it up into 10-minute intervals.

How to control blood pressure and cholesterol?

Eat healthy foods. A heart-healthy diet full of fruits, vegetables and whole grains — and low in refined carbohydrates, sugars, saturated fat and sodium — can help you control your weight, blood pressure, cholesterol and blood sugar. Try substituting whole-grain bread in place of white bread.

What is the best test for atherosclerosis?

High levels of blood sugar and cholesterol raise your risk of atherosclerosis. A C-reactive protein (CRP) test also may be done to check for a protein linked to inflammation of the arteries. Electrocardiogram (ECG or EKG). This simple and painless test records the electrical signals in your heart. Exercise stress test.

Is it too early to make healthy lifestyle changes?

What you can do in the meantime. It's never too early to make healthy lifestyle changes, such as quitting smoking, eating healthy foods and getting more exercise. These are simple ways to protect yourself against atherosclerosis and its complications, including heart attack and stroke. By Mayo Clinic Staff.

How to prevent atherosclerosis?

You can do this with lifestyle changes such as exercising every day; eating a heart-healthy diet; not smoking; and controlling high blood pressure, high cholesterol, and high blood sugar. Taking a low-dose aspirin every day is also important.

What is the difference between a healthy artery and an atherosclerotic artery?

A healthy artery is like a clean pipe: It has a smooth lining and is free of blockages that interfere with blood flow. Atherosclerosis is the buildup of cholesterol-filled deposits called plaque on the inner walls of arteries. Plaque narrows the vessels and slows down blood flow.

What happens to the white blood cells in the artery wall?

Cells from the wall of the artery gradually surround the mixture. The artery wall becomes inflamed; white blood cells become activated, race to the injured area, and try unsuccessfully to heal the damage. Over time, a fibrous cap forms over the fatty deposit.

Where does atherosclerosis occur?

Atherosclerosis can occur in any artery in the body, from those nourishing the heart (coronary arteries) to those supplying the brain, intestines, kidneys, and legs. Atherosclerosis begins as microscopic damage to the inner lining of an artery wall.

Can fibrous cap cause heart attacks?

Even under the cap, the deposit can grow, progressively blocking blood flow and ultimately causing chest pain (angina). If the fibrous cap ruptures, a blood clot can form. Such blood clots are the cause of heart attacks and strokes.

Does statin help with heart disease?

Taking a cholesterol-lowering statin can keep atherosclerosis from getting worse, and can also pull cholesterol out of artery-clogging plaque. Statins can also help stabilize atherosclerotic plaques and keep them from breaking open—the event that triggers most heart attacks and strokes.

How does atherosclerosis prognosis depend on systemic burden?

The prognosis of atherosclerosis also depends on systemic burden of disease, the vascular bed (s) involved, and the degree of flow limitation. Wide variability is noted, and clinicians appreciate that many patients with critical limitation of flow to vital organs may survive many years, despite a heavy burden of disease.

What are the factors that affect the prognosis of atherosclerosis?

The prognosis in patients with atherosclerosis depends on the following factors: The prognosis of atherosclerosis also depends on systemic burden of disease, the vascular bed (s) involved, and the degree of flow limitation. Wide variability is noted, and clinicians appreciate that many patients with critical limitation of flow to vital organs may ...

What are the prognostic factors for atherosclerosis?

The prognosis in patients with atherosclerosis depends on the following factors: 1 Presence of inducible ischemia 2 Left ventricular function 3 Presence of arrhythmias 4 Revascularization potential (complete vs incomplete) 5 Aggressiveness of risk alteration 6 Compliance with medical therapy

How is atherosclerosis limited?

The ability to determine and quantify risk and prognosis in patients with atherosclerosis is limited by the inability to objectively measure plaque stability and other predictors of clinical events. Related Questions:

What is the treatment for atherosclerosis?

Abdomen — When atherosclerosis narrows arteries that supply the bowel, the patient may be treated with balloon angioplasty with or without stents or a bypass arterial graft. Legs — The mainstays of treatment for peripheral artery disease are quitting smoking, exercise (usually a walking program), and aspirin.

What are the factors that increase the risk of atherosclerosis?

Factors that increase your risk of developing atherosclerosis include: High level of blood cholesterol (hypercholesterolemia), especially LDL ("bad cholesterol) Low level of HDL ("good cholesterol") High levels of C-reactive protein, a marker for inflammation. High blood pressure (hypertension) Diabetes.

What is the term for the narrowing of the arteries?

Atherosclerosis is a narrowing of the arteries that can significantly reduce the blood supply to vital organs such as the heart, brain and intestines. In atherosclerosis, the arteries are narrowed when fatty deposits called plaques build up inside. Plaques typically contain cholesterol from low-density lipoproteins (LDL), ...

What is the underlying medical problem in most patients with any of the following illnesses?

This is because atherosclerosis is the underlying medical problem in most patients with any of the following illnesses: Coronary artery disease — In this chronic (long-lasting) disease, atherosclerosis narrows the coronary arteries, the arteries that supply blood to the heart muscle.

What is it called when symptoms disappear?

If symptoms completely disappear within an hour or a bit longer, the episode is called a transient ischemic attack (TIA). When atherosclerosis completely blocks the brain arteries and/or the above symptoms last longer, it's generally called a stroke.

Can atherosclerosis be prevented?

For many, this is disease can be prevented. Even those people genetically programmed for atherosclerosis can delay the beginning and worsening of the disease with a healthy lifestyle, the right foods, and medication to lower LDL cholesterol.

Is there a cure for atherosclerosis?

Treatment. There is no cure for atherosclerosis, but treatment can slow or halt the worsening of the disease. The major treatment goal is to prevent significant narrowing of the arteries so that symptoms never develop and vital organs are never damaged.

What are the complications of atherosclerosis?

Complications. The complications of atherosclerosis depend on which arteries are blocked. For example: Coronary artery disease. When atherosclerosis narrows the arteries close to your heart, you may develop coronary artery disease, which can cause chest pain (angina), a heart attack or heart failure.

What happens if you have atherosclerosis in your legs?

If you have atherosclerosis in the arteries in your arms and legs, you may have signs or symptoms of peripheral artery disease, such as leg pain when walking (claudication) or decreased blood pressure in an affected limb. If you have atherosclerosis in the arteries leading to your kidneys, you develop high blood pressure or kidney failure.

What happens when an artery is damaged?

Once the inner wall of an artery is damaged, blood cells and other substances often clump at the injury site and build up in the inner lining of the artery. Over time, fatty deposits (plaque) made of cholesterol and other cellular products also build up at the injury site and harden, narrowing your arteries.

How do you know if you have atherosclerosis?

If you have atherosclerosis in the arteries leading to your brain, you may have signs and symptoms such as sudden numbness or weakness in your arms or legs, difficulty speaking or slurred speech, temporary loss of vision in one eye, or drooping muscles in your face.

What happens if you have a blocked artery?

The organs and tissues connected to the blocked arteries then don't receive enough blood to function properly. Eventually, pieces of the fatty deposits may break off and enter your bloodstream. In addition, the smooth lining of the plaque may rupture, spilling cholesterol and other substances into your bloodstream.

What are the symptoms of inadequate blood flow?

Also pay attention to early symptoms of inadequate blood flow, such as chest pain (angina), leg pain or numbness. Early diagnosis and treatment can stop atherosclerosis from worsening and prevent a heart attack, stroke or another medical emergency.

Can a blood clot cause a heart attack?

Sometimes a blood clot completely blocks blood flow, or even breaks apart and can trigger a heart attack or stroke. Symptoms of moderate to severe atherosclerosis depend on which arteries are affected. For example:

What Is Arteriosclerosis?

Arteriosclerosis is the general name for a group of conditions that cause arteries to become thick and stiff. Healthy arteries are stretchy and flexible, and they carry oxygen and nutrients via blood to and from your heart and lungs. When they stiffen, blood flow gets interrupted, causing circulation problems.

What Are the Warning Signs of Arteriosclerosis?

Lots of people don’t know they have arteriosclerosis until they have a heart attack or aneurysm. An aneurysm happens when the artery walls weaken, widen, and bulge.

What Is the Treatment for Arteriosclerosis?

Depending on the kind and severity of your condition, your doctor may recommend lifestyle changes such as:

What Is Atherosclerosis?

Atherosclerosis is a specific type of arteriosclerosis. It happens when plaque, cholesterol, and fatty substances build up in your arteries and cause them to narrow. This buildup can lead to an artery blockage that disrupts blood flow.

What Are the Signs of Atherosclerosis?

Like arteriosclerosis, lots of people may not know they have atherosclerosis until they have a heart attack. You might have some signs like:

What Is the Treatment for Atherosclerosis?

Atherosclerosis treatment includes lifestyle and dietary changes similar to those for arteriosclerosis. Your doctor may prescribe medications as well as some surgical or nonsurgical procedures.

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Diagnosis

Treatment

Clinical Trials

Lifestyle and Home Remedies

Medically reviewed by
Dr. Kabir Sethi
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Lifestyle changes, such as eating a healthy diet and exercising, are often recommended. Management of the condition involves medications and surgery in severe cases.
Medication

Angiotensin-converting enzyme (ACE) inhibitors: Lowers blood pressure.

Benazepril . Captopril . Enalapril


Calcium channel blockers: Helps in lowering blood pressure.

Nifedipine


Diuretics: Diuretics lower blood pressure.

Indapamide


Beta blockers: Can lower blood pressure and slow down progression of atherosclerosis.

Acebutolol . Betaxolol


Statins: Lower the levels of bad cholesterol (LDL).

Atorvastatin . Fluvastatin


Anti platelet medications: Helps in reducing the formation of platelet clumps in narrowed arteries.

Aspirin


Fibrinolytic enzymes: Therapy to break the clot apart using clot-dissolving enzymes.

Streptokinase . Urokinase

Procedures

Angioplasty and stent placement: Insertion of catheters to place a stent and keep the artery open

Endarterectomy: In this procedure, fatty deposits are surgically removed from the walls of a narrowed artery.

Bypass surgery: Graft bypass using a vessel from another part of the body that helps smooth blood flow.

Self-care

Always talk to your provider before starting anything.

Eat a healthy, balanced diet, a good mix of unsaturated fats, exercise regularly, quit smoking and alcohol.

Nutrition

Foods to eat:

  • Major portion of the diet should include vegetables, beans, whole grains, and fruit.
  • Foods rich in protein and monounsaturated fatty acids.
  • Omega-3 fatty acids: fish such as sardine, salmon and grains or seeds such as flaxseed, walnuts, chia seeds.

Foods to avoid:

  • Minimize refined grains, added salt, and sweeteners.
  • Avoid foods containing trans and saturated fats.
  • Avoid foods high in salt and sugar.

Specialist to consult

Cardiologist
Specializes in the diagnosis and management heart related disorders.

Alternative Medicine

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Atherosclerosisis a common disease that occurs when the inside of arteries have plaque buildup. Similar to your teeth, your arteries form many layers of plaque that can be difficult to remove. The big difference is that plaque on your teeth is only a minor nuisance compared to the kind of plaque that can build up inside your arteri…
See more on study.com

Preparing For Your Appointment

What Is Atherosclerosis?

Symptoms

Diagnosis

  • Lifestyle changes, such as eating a healthy diet and exercising, are the first treatment for atherosclerosis — and may be all that you need to treat your atherosclerosis. But sometimes, medication or surgical procedures may be needed.
See more on mayoclinic.org

Expected Duration

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Prevention

  • Lifestyle changes can help you prevent or slow the progression of atherosclerosis. 1. Stop smoking.Smoking damages your arteries. Quitting smoking is the best thing you can do to keep your arteries healthy and prevent atherosclerosis complications. 2. Exercise most days of the week. Regular exercise improves blood flow, lowers blood pressure, and r...
See more on mayoclinic.org

Treatment

  • It's thought that some foods and herbal supplements can help reduce your high cholesterol level and high blood pressure, two major risk factors for developing atherosclerosis. With your doctor's OK, you might consider these supplements and products: 1. Alpha-linolenic acid 2. Barley 3. Beta-sitosterol (found in supplements and some margarines, such as Promise Activ) 4. Blond psylliu…
See more on mayoclinic.org

When to Call A Professional

  • If you think you may have atherosclerosis or are worried about having atherosclerosis because of a strong family history of heart disease, make an appointment with your doctor to have your cholesterol level checked. Here's some information to help you get ready for your appointment and know what to expect from your doctor.
See more on mayoclinic.org

Prognosis

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Atherosclerosis is a narrowing of the arteries that can significantly reduce the blood supply to vital organs such as the heart, brain and intestines. In atherosclerosis, the arteries are narrowed when fatty deposits called plaques build up inside. Plaques typically contain cholesterol from low-density lipoproteins (LD…
See more on drugs.com

Further Information

  • Atherosclerosis usually doesn't cause any symptoms until blood supply to an organ is reduced. When this happens, symptoms vary, depending on the specific organ involved: 1. Heart — Symptoms include the chest pain of angina and shortness of breath, sweating, nausea, dizziness or light-headedness, breathlessness or palpitations. 2. Brain — When ather...
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