Treatment FAQ

what is the most effective treatment for a b12 deficiency

by Dr. Daisy Koch Published 2 years ago Updated 2 years ago
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Vitamin B12 deficiency can be treated with intramuscular injections of cyanocobalamin or oral vitamin B12 therapy. Approximately 10% of the standard injectable dose of 1 mg is absorbed, which allows for rapid replacement in patients with severe deficiency or severe neurologic sy mptoms.Sep 15, 2017

Full Answer

What foods increase B12 levels?

The Best Method to Increase Vitamin B12 Levels

  • Test for Deficiency. Vegetarians may be at risk for vitamin B12 deficiency, despite the fortification of many common foods.
  • Eat Animal Products. Animal products, including meat, poultry, seafood and dairy foods, are the main source of cobalamin in the diet.
  • Use Dairy Substitutes. ...
  • Take Dietary Supplements. ...
  • Eat Fortified Foods. ...

What drugs cause B12 deficiency?

This can be caused by an underlying condition that affects one of your organs, such as:

  • congestive heart failure – where the heart is unable to pump enough blood around the body
  • acute liver damage – often caused by drinking excessive amounts of alcohol
  • long-term dialysis – where a machine that replicates the kidney function is used to filter waste products from the blood

What are the warning signs of a B12 deficiency?

What Are The Warning Signs of Vitamin B12 Deficiency?

  1. Fatigue. Low levels of Vitamin B12 in the blood often results in immense fatigue and unnecessary tiredness. ...
  2. Canker Sores. Some of the earliest Vitamin B12 deficiency symptoms are visible in the mouth, especially on the tongue.
  3. Mood Shifts. ...
  4. Blurry Vision. ...
  5. Pale Skin Patches. ...
  6. Nervous System Issues. ...
  7. Constipation. ...
  8. Infertility. ...

Can you take too much B12?

The answer is yes. Hypercobalaminemia is the medical term for having high serum vitamin B12 levels. Credible reports suggest various reasons why a person may have excessive B12.

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What is the fastest way to fix B12 deficiency?

How to Raise Your B12 Levels Fast. The most common way to treat B12 deficiencies is by adjusting your diet. If this is unsuccessful, vitamin supplements may be recommended. If you're looking to boost the amount of vitamin B12 in your diet, you should eat more animal products, like meat, seafood, dairy and eggs.

Which medicine is best for B12 deficiency?

You'll usually take cyanocobalamin tablets every day to prevent or treat vitamin B12 deficiency. However, you may also need vitamin B12 injections at first to boost your levels. It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve.

How long does it take to correct a B12 deficiency?

Recovery from vitamin B12 deficiency takes time. You may not have any improvement during the first few months of treatment. Improvement may be gradual and may continue for up to six to 12 months.

Are B12 tablets as effective as injections?

In both studies, high-dose oral B12 was as effective as intramuscular injection at achieving neurologic and hematologic response. Vitamin B12 is available over the counter in the form of tablets (100, 500, 1,000, or 5,000 mcg) and lozenges (50, 100, 250, or 500 mcg).

What is the most common cause of B12 deficiency?

Pernicious anaemia is the most common cause of vitamin B12 deficiency in the UK. Pernicious anaemia is an autoimmune condition that affects your stomach. An autoimmune condition means your immune system, the body's natural defence system that protects against illness and infection, attacks your body's healthy cells.

How quickly do B12 injections work?

Since B12 shots are injected intramuscularly bypassing the digestive process, they start to work immediately. Typically, our patients experience positive effects between 24-72 hours after the treatment.

What are the neurological symptoms of B12 deficiency?

A lack of vitamin B12 can cause neurological problems, which affect your nervous system, such as:vision problems.memory loss.pins and needles (paraesthesia)loss of physical co-ordination (ataxia), which can affect your whole body and cause difficulty speaking or walking.More items...

What disease is associated with a deficiency of B12?

Either a lack of vitamin B-12 or a lack of folate causes a type of anemia called megaloblastic anemia (pernicious anemia). With these types of anemia, the red blood cells don't develop normally.

What happens if B12 is left untreated?

If left untreated, the symptoms of vitamin B12 deficiency tend to worsen and irreversible problems involving the nerves and brain may develop. The risk of experiencing a number of serious complications, including heart failure, may also increase.

Which is better B12 tablets or B12 injections?

Which is better—the B12 pill or the shot? A. Low B12 can cause anemia and fatigue. For many people with low B12 levels, a daily supplement in the form of a pill is as effective as taking a monthly muscle injection.

What can I take instead of B12 injections?

Oral vitamin B12 replacement at 1000 μg daily is an adequate alternative to IM B12 injections. Close monitoring with clinical review and repeat vitamin B12 levels are required on a monthly basis to review symptoms and ensure normalization of B12 deficiency.

How can I raise my B12 levels fast?

To increase the amount of vitamin B12 in your diet, eat more of foods that contain it, such as:Beef, liver, and chicken.Fish and shellfish such as trout, salmon, tuna fish, and clams.Fortified breakfast cereal.Low-fat milk, yogurt, and cheese.Eggs.

How to treat vitamin B12 deficiency?

Most people can be easily treated with injections or tablets to replace the missing vitamins.

What foods contain B12?

meat. salmon and cod. milk and other dairy products. eggs. If you're a vegetarian or vegan, or are looking for alternatives to meat and dairy products, there are other foods that contain vitamin B12, such as yeast extract ( including Marmite), as well as some fortified breakfast cereals and soy products.

Can you take folic acid for life?

But if the underlying cause of your folate deficiency anaemia continues, you may have to take folic acid tablets for longer, possibly for life. Before you start taking folic acid, your GP will check your vitamin B12 levels to make sure they're normal.

Can you stop taking B12?

Although it's less common, people with vitamin B12 deficiency caused by a prolonged poor diet may be advised to stop taking the tablets once their vitamin B12 levels have returned to normal and their diet has improved. Good sources of vitamin B12 include: meat. salmon and cod. milk and other dairy products.

Can vitamin B12 be given to a GP?

Your GP or nurse will give the injections. After this initial period, your treatment will depend on whether the cause of your vitamin B12 deficiency is related to your diet or whether the deficiency is causing any neurological problems, such as problems with thinking, memory and behaviour. The most common cause of vitamin B12 deficiency in ...

Do you need to monitor for vitamin B12?

Most people who have had a vitamin B12 or folate deficiency will not need further monitoring unless their symptoms return or their treatment is ineffective. If your GP feels it's necessary, you may have to return for an annual blood test to see whether your condition has returned. Page last reviewed: 23 May 2019.

Can you get cyanocobalamin injections on the NHS?

Cyanocobalamin injections are not routinely available on the NHS as hydroxocobalamin is the preferred treatment. But if you need replacement tablets of vitamin B12, these will usually be in the form of cyanocobalamin.

How much B12 is needed for a shot?

The standard vitamin b 12 dosage is approximately 1000 mcg. If the doctor is not educated on the current science of Vitamin B12 and tells you that you have B12 Malabsorption , then he will often prescribe Vitamin B12 shots. But before you get vitamin B12 injections, you should be aware of the Vitamin B12 Shot Problems - including the fact ...

How long does it take for the liver to replenish vitamin B12?

The liver stores up to 3 years of vitamin B12, and if you are deficient then your liver stores were depleted as well. It may take some time to 'fill up your tank' with vitamin B12, but when you do- it's likely that you will be able to decrease your daily vitamin b 12 dosage and still feel good.

How long does it take to feel better after taking B12?

This strategy acts more like getting a B12 shot and people often feel better within a few days to a week. Since the dosages usually come in smaller dosages of 1000 to 2000 micrograms per tablet, simply start off with one tablet and see how you feel. A few hours later, take another tablet.

Does vitamin B12 deficiency work for one person?

One vitamin B12 deficiency treatment that works for one person may not work for YOU - that does NOT mean that you are weird or sicker than other people, you just have different, individual Vitamin B12 Supplement needs that you need to be patient and find for yourself. Next--->. Vitamin B12 Deficiency Symptoms.

Can you take B12 for long periods of time?

High Dose Treatment is Not Forever. Even if you need a very high dosage for vitamin B12 deficiency treatment, for serious Vitamin B12 Malabsorption, you may not need to take this dose for long periods of time. The liver stores up to 3 years of vitamin B12, and if you are deficient then your liver stores were depleted as well.

Is B12 a good vitamin?

Safety of High Dosages of B12. In the above study that averaged 9 milligrams per day, there were no adverse effects or side effects. Vitamin B12 is an EXTREMELY safe vitamin to take.

Is B12 good for blood levels?

While studies have shown that this dose is effective to bring up vitamin B12 BLOOD LEVELS, the Facts about Vitamin B12 show that that this is often not a high enough vitamin b 12 dosage to make people feel as well as they could- and THAT is what is important to YOU.

Overview

Vitamin B-12 (cobalamin) plays an essential role in red blood cell formation, cell metabolism, nerve function and the production of DNA, the molecules inside cells that carry genetic information.

Evidence

Research on the use of vitamin B-12 for specific activities and conditions shows:

Our take

Most people get enough vitamin B-12 from a balanced diet. However, older adults, vegetarians, vegans and people who have conditions that affect their ability to absorb vitamin B-12 from foods might benefit from the use of oral supplements.

Safety and side effects

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

Interactions

Aminosalicylic acid (Paser). Taking this drug used to treat digestive problems might reduce your body's ability to absorb vitamin B-12.

What is B12 used for?

Vitamin B12 functions as a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase [ 1-3, 5 ] . Methionine synthase catalyzes the conversion of homocysteine to the essential amino acid methionine [ 1, 2 ].

What is the most common cause of vitamin B12 deficiency?

Pernicious anemia is the most common cause of clinically evident vitamin B12 deficiency around the world [ 11, 43 ]. The incidence of pernicious anemia in the United States is an estimated 151 per 100,000, and this condition is more common in women and in people of European ancestry [ 43 ].

What is B12 parenteral?

Parenteral administration is typically used to treat vitamin B12 deficiency caused by pernicious anemia as well as other conditions (e.g., tropical sprue, pancreatic insufficiency) that result in vitamin B12 malabsorption and severe vitamin B12 deficiency [ 5 ].

How long does it take for a vitamin B12 deficiency to appear?

Because the body stores about 1 to 5 mg vitamin B12 (or about 1,000 to 2,000 times as much as the amount typically consumed in a day), the symptoms of vitamin B12 deficiency can take several years to appear [ 7, 33 ].

What is the most common form of vitamin B12?

The most common form of vitamin B12 in dietary supplements is cyanocobalamin [ 1, 3, 22, 23 ]. Other forms of vitamin B12 in supplements are adenosylcobalamin, methylcobalamin, and hydroxycobalamin [ 22 ]. No evidence indicates that absorption rates of vitamin B12 in supplements vary by form of the vitamin.

How much B12 is in a multivitamin?

Multivitamin/mineral supplements typically contain vitamin B12 at doses ranging from 5 to 25 mcg [ 22 ]. Vitamin B12 levels are higher, generally 50–500 mcg, in supplements containing vitamin B12 with other B-complex vitamins and even higher, typically 500–1,000 mcg, in supplements containing only vitamin B12.

Why is vitamin B12 not UL?

The FNB did not establish a UL for vitamin B12 because of its low potential for toxicity [ 1 ]. Even at large doses, vitamin B12 is generally considered to be safe because the body does not store excess amounts.

What are the conditions that require B12?

You need this to absorb B12 from food. Digestive disorders. That includes conditions like Crohn’s disease, ulcerative colitis, or celiac disease. Liver problems. You need a healthy liver to store B12. Diet. Vegans or vegetarians are more likely to have a B 12 deficiency.

Who needs B12?

Your doctor can let you know which dose is right for you. Certain groups may need to take a B12 supplement for life. These include: Vegans or strict vegetarians. People who’ve had surgery for weight loss or stomach cancer. People with pernicious anemia. People older than 50. Food.

What to expect after B12 treatment?

What to Expect After Treatment. Cells all over your body depend on vitamin B12. But you don’t make this nutrient on your own. And you sometimes may not get enough of it. What you do or don’t eat, along with certain surgeries or other health problems, may be the reason. Treatment for a B12 deficiency is pretty simple.

Why do older people have a B12 deficiency?

Causes of B12 deficiency include: Aging. Older adults tend to have less of the stomach acid you need to absorb B12 from food. Pernicious anemia. This is an immune system disorder that affects cells in your stomach. If you have it, you don’t make enough of a protein called intrinsic factor.

How to get B12 out of stomach?

Surgery. Any procedure that takes out part or all of your stomach will likely lower the number of cells that help you absorb B12. Medication. Certain drugs, including metformin and antacids, can lessen your body’s ability to take in B12. Alcohol misuse. You may not eat enough B12-rich foods if you drink a lot.

What happens if you run low on B12?

If you run low for a long time, it can lead to serious health issues. That includes memory problems or nerve damage that may not go away. If you’re low in B12 or think you are, talk to your doctor. Here are some ways they can help.

What foods are B12?

Some B12 sources include: Clams. Liver and beef. Trout and salmon. Canned tuna. Low-fat milk. Low-fat yogurt.

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