Treatment FAQ

what is the key treatment for narcolepsy

by Meredith Cummings Published 2 years ago Updated 2 years ago
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Medication

Treating narcolepsy without medication

  • cultivating a habit for keeping a regular sleep schedule
  • taking scheduled long day time naps or timed short naps
  • developing habit for taking short 20-minutes naps across different parts of a day
  • handle a sleep attack with preparedness by scheduling meetings, work
  • regular exercise
  • avoiding alcohol. ...
  • nutritious diet

More items...

Nutrition

There is no cure for narcolepsy, but medications and lifestyle modifications can help you manage the symptoms. Medications for narcolepsy include: Stimulants. Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day.

What is the best natural treatment for narcolepsy?

What to Eat

  • Follow a heart-healthy diet. Narcolepsy increases your risk of stroke, heart attack, and heart failure. ...
  • Try a low-carb diet. When you eat a big, high-carb meal, your body makes less of the hormone ghrelin, which stimulates wakefulness.
  • Consider a keto diet. ...
  • Try caffeine. ...
  • Avoid alcohol. ...

Will there ever be a cure for narcolepsy?

There's no specific cure for narcolepsy, but you can manage the symptoms and minimise their impact on your daily life. Making some simple changes to your sleeping habits can sometimes help. If your symptoms are more severe, you'll usually need to take medicine.

What is a good diet for someone with narcolepsy?

Can you cure narcolepsy?

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What is the primary treatment for narcolepsy?

Stimulants. Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day. Doctors often try modafinil (Provigil) or armodafinil (Nuvigil) first for narcolepsy.

How is narcolepsy cured?

Although there is no cure for narcolepsy, some of the symptoms can be treated with medicines and lifestyle changes. When cataplexy is present, the loss of hypocretin is believed to be irreversible and lifelong. Excessive daytime sleepiness and cataplexy can be controlled in most individuals with medications.

Can narcolepsy be treated without medication?

Just staying awake through the daylight hours can be difficult or impossible. Prescription drugs are often the go-to therapy for this brain disorder. But changes to your diet, habits, and environment also can help keep you alert without the side effects from medications.

How do you stop narcolepsy naturally?

For narcolepsy, this can range from lifestyle changes, melatonin supplements, and natural herbal extracts to trying yoga or acupuncture for a better wake-sleep cycle.

What are 2 triggers for narcolepsy?

Things that have been suggested as possible triggers of narcolepsy include: hormonal changes, which can occur during puberty or the menopause. major psychological stress. an infection, such as swine flu, or the medicine used to vaccinate against it (Pandemrix)

How do you replace hypocretin?

There are many potential approaches to replace hypocretin in the brain for narcolepsy such as intranasal administration of hypocretin peptides, developing small molecule hypocretin receptor agonists, hypocretin neuronal transplantation, transforming hypocretin stem cells into hypothalamic neurons, and hypocretin gene ...

What vitamins help narcolepsy?

Supplements for Narcolepsy Some people with narcolepsy have tried dietary supplements and vitamins to manage their symptoms. In particular, these individuals reported trying omega-3 supplements, B-complex vitamins, and magnesium to address cognitive issues associated with the condition.

Does magnesium help narcolepsy?

Certain nutrients, such as magnesium and vitamin B, may help control narcolepsy symptoms. A diet rich in nutrients and low in carbohydrates will optimize the body's performance throughout the day.

Does caffeine help narcolepsy?

Conclusion: Our findings suggest that a small dose of caffeine has positive effects on alertness in patients with narcolepsy.

How do you get sodium oxybate?

Sodium oxybate is not available at retail pharmacies. Sodium oxybate is available only through a restricted distribution program called the Xywav and Xyrem REMS Program. It is a special program to distribute the medication and provide information about the medication.

Does exercise help narcolepsy?

While the symptoms of narcolepsy can be difficult to manage, exercise can improve alertness, focus and energy levels. Yes. One of the best ways to reduce narcolepsy symptoms is to exercise. Sitting for extended periods can make anyone tired, but it can have a particularly sedating effect on people with narcolepsy.

Does melatonin help narcolepsy?

Melatonin has also been used to alter sleep architecture in narcolepsy, a disorder of disturbed circadian sleep/wake rhythm and rapid-eye-movement (REM) sleep deficit. Changes in REM sleep patterns similar to those of narcolepsy also occur in animals and humans after removal of the pineal gland.

How to treat narcolepsy?

Treatment for narcolepsy can be broken down into two categories: 1 Behavioral approaches employ changes in lifestyle and daily habits to manage symptoms and reduce the likelihood of other physical and emotional challenges that often affect people with narcolepsy. 2 Medications can be prescribed to address symptoms. The use of medications is known as pharmacotherapy.

How many medications do you need to treat narcolepsy?

To treat narcolepsy, doctors usually start with one drug to see how well it works for a specific patient. The dosage or timing of doses may be changed as needed, or the doctor may recommend switching medications if the first is not working or well-tolerated.

What is the name of the disorder where you fall asleep involuntarily?

Narcolepsy is a disorder in which the sleep-wake cycle is significantly altered 1. Its central symptom is excessive daytime sleepiness (EDS), which may involve falling asleep involuntarily, even while eating or driving. People with narcolepsy face safety risks including a three- to four-fold increase 2 in their chances of being in an automobile ...

How to sleep better with narcolepsy?

Practical tips to improve sleep routines for people with narcolepsy include: Keep a consistent bedtime and wake time: A stable sleep schedule can ensure that enough time is budgeted for rest and helps habituate the body to sleeping at set times, including at night.

Why is it important to eat healthy when you have narcolepsy?

Eating a healthy diet is important for everyone, but it takes on added importance for people with narcolepsy because they have an elevated risk of obesity. The timing of meals is important as well. Eating too late at night may interfere with normal digestion and is associated with sleep disruptions 8.

What is the symptom of narcolepsy?

There are two types of narcolepsy 3. Narcolepsy type 1 (NT1) frequently involves a symptom called cataplexy, which is a sudden and brief loss of muscle tone in which the individual is conscious. It is triggered by strong emotions, usually positive ones like laughter.

What is behavioral approach in narcolepsy?

Behavioral approaches employ changes in lifestyle and daily habits to manage symptoms and reduce the likelihood of other physical and emotional challenges that often affect people with narcolepsy. Medications can be prescribed to address symptoms. The use of medications is known as pharmacotherapy.

Narcolepsy Treatment

Narcolepsy is a neurological condition that inhibits one’s ability to control and regulate sleep-wake cycles. There is no known cure for narcolepsy, but there are a variety of treatments 1 to alleviate and control the symptoms of narcolepsy.

Medications to Treat Narcolepsy

There are several medications that can combat and help reduce the effects of narcolepsy. Typically, these medications fall into two categories: stimulants that promote alertness and wakefulness; and anti-depressants and sedatives that help ensure a more regulated sleep, treat cataplexy, and can decrease overall anxiety.

Lifestyle changes

Because narcolepsy is a chronic lifelong condition with a wide range of different symptoms and causes, it is important to seek medical help to determine the right combination of medication and lifestyle adjustments. Besides medications, there are several ways people can adapt their lifestyle to reduce the effects of narcolepsy.

What is the best treatment for narcolepsy?

Central nervous system stimulants are the main treatments used for excessive daytime sleepiness in narcolepsy, and these stimulants include Amphetamine, Methylphenidate, Modafinil, Dextroamphetamine and Armodafinil.

Is it hard to control narcolepsy?

It’s extremely difficult to fully control the symptoms of narcolepsy, and medication adjustments are often necessary . Lifestyle changes are also very important for people suffering from narcolepsy, with oral medications being the mainstay of treatment.

Is narcolepsy a depression?

As mentioned previously, narcolepsy can be confused with depression, and it’s true that there is a link between these two disorders. The co-occurrence of depression in narcolepsy patients has produced mixed results, though, with different studies producing numbers anywhere between 6% and 50%. Author. Recent Posts.

Can narcolepsy be cured?

Although people suffering from narcolepsy can’t be cured, they can be helped. Treatment for this disorder is tailored to each individual and is based on the person’s symptoms and therapeutic response. It could well take months, or even longer, to achieve effective control of symptoms.

Is narcolepsy a neurological disorder?

Narcolepsy can be described as a neurological condition involving a person’s reduced ability to manage the sleep-wake cycle. Although people suffering from narcolepsy can’t be ...

Is narcolepsy more common than fibrosis?

In fact, narcolepsy is as prevalent as Multiple Sclerosis and Parkinson’s disease, and more common than Cystic Fibrosis, but unfortunately it’s just not as well known. The reason for this is that narcolepsy can often be confused with epilepsy, depression, or the side-effect of medications.

Can narcolepsy run in families?

The symptoms of narcolepsy are generally first noticed in young adults or teenagers, but narcolepsy can occur in both women and men at any age. In fact, there’s strong evidence that narcolepsy could run in families, because approximately 10% of people diagnosed with narcolepsy with cataplexy already have a close family member with this neurological disorder. As mentioned previously, narcolepsy can be confused with depression, and it’s true that there is a link between these two disorders. The co-occurrence of depression in narcolepsy patients has produced mixed results, though, with different studies producing numbers anywhere between 6% and 50%.

What are the symptoms of narcolepsy?

The symptoms of narcolepsy can have notable effects during both daytime and night time. The most common symptoms include: Excessive daytime sleepiness (EDS): EDS is the cardinal symptom of narcolepsy, affecting all people with the disorder. EDS involves an urge to sleep that can feel irresistible, and it arises most frequently in monotonous ...

What is narcolepsy sleep disorder?

Narcolepsy is a sleep disorder that is often misunderstood. It is characterized by severe and persistent daytime sleepiness that can cause impairments in school, work, and social settings as well as heighten the risk of serious accidents and injuries.

How long does cataplexy last?

Cataplexy normally affects both sides of the body and lasts for a few seconds to a few minutes. Some people with NT1 only have episodes of cataplexy a few times per year, while others can have a dozen or more episodes per day. Although all people with narcolepsy have EDS, less than a quarter have all of these symptoms.

How rare is narcolepsy?

Narcolepsy is relatively rare. NT1 affects between 20 and 67 people per 100,000 in the United States. According to a population based study in Olmstead county Minnesota, NT1 is two to three times more common 4 than NT2, which is estimated to affect between 20 to 67 people per 100,000.

How long does narcolepsy go undiagnosed?

Because it is rare and symptoms may be mistakenly attributed to other causes, narcolepsy can go undiagnosed for many years. The diagnostic process starts with a review of symptoms and medical history.

Is narcolepsy a health issue?

The symptoms of narcolepsy can have significant consequences for a patient’s health and wellness. Accidents are a pressing concern as sleep attacks, drowsiness, and cataplexy can be life-threatening when driving or in other environments where safety is critical.

Is NT2 a cataplexy?

NT2 was formerly known as “narcolepsy without cataplexy.” People with NT2 have many similar symptoms as people with NT1, but they do not have cataplexy or low levels of hypocretin-1.

Official Answer

There is no cure for narcolepsy, but medications and lifestyle modifications can help manage symptoms such as excessive daytime sleepiness (EDS). Medications include:

What lifestyle changes help with narcolepsy?

Lifestyle modifications can help manage symptoms of narcolepsy, and can include:

What are the best medications for narcolepsy?

Drugs that act as stimulants and/or reduce the other symptoms of narcolepsy are standard treatments for the condition. They include: Armodafinil ( Nuvigil ): This drug is similar to Provigil. It is also used to reduce excessive daytime sleepiness. Headache and nausea are the most common side effects. Methylphenidate Hcl ( Daytrana, Ritalin ...

How to help narcolepsy stay awake?

It has proven effective in helping patients stay awake for longer periods of time. Home Remedies for Narcolepsy. There are several things you can do at home to help improve the symptoms of narcolepsy and include the following: Maintain a regular sleep schedule.

Can narcolepsy be taken one day a week?

Therefore, some doctors advise people with narcolepsy to abstain from taking it one day each week (typically on a weekend).

Does Pitolisant work on histamine receptors?

It acts on the histamine receptors and mimics histamine. Pitolisant uses the histamine receptors to prompt your brain to stay awake. Solriamfetol ( Sunosi ): This dual-acting dopamine and norepinephrinere uptake inhibitor is also used to treat narcolepsy.

Medications for narcolepsy

Medications cannot cure narcolepsy, but they can help you manage your symptoms. According to the National Institute for Neurological Disorders and Stroke (NINDS), most people can manage the excessive sleepiness and cataplexy related to narcolepsy by using a combination of behavioral changes and medications.

Behavioral therapy

Along with medications, various behavioral techniques can help in narcolepsy treatment. These involve lifestyle strategies that help promote better nighttime sleep and daytime alertness.

Self-care

Living with narcolepsy can be challenging. Making simple changes to your sleep habits and lifestyle can help manage symptoms and minimize their impact on your daily life.

Next steps

Not only is narcolepsy a challenging condition to live with, but it can also be difficult for others to understand. Some of the symptoms can be frightening for people who are unaware of the condition.

Medications Can Help Keep Narcolepsy Symptoms Under Control

For most individuals who have narcolepsy, medications can help with some of the disorder’s most burdensome symptoms, according to Richard K. Bogan, MD , associate clinical professor at the University of South Carolina School of Medicine and Chief Medical Officer of the sleep diagnostic company SleepMed, based in Columbia, South Carolina.

Sticking to a Regular Sleep Schedule Is an Important Part of Managing Narcolepsy

In addition to medications, lifestyle changes can make a big difference in managing the symptoms of narcolepsy.

Experts Say Better Narcolepsy Treatment Options Are on the Horizon

The more common type of narcolepsy (type 1), which is the type where people experience cataplexy along with other symptoms, happens because an individual has lower than usual levels of hypocretin (also called orexin, a key brain chemical that regulates sleep and wakefulness), according to the Stanford Medicine Center for Narcolepsy.

Editorial Sources and Fact-Checking

Narcolepsy Fact Sheet. National Institute of Neurological Disorders and Stroke. July 6, 2018.

Drugs used to treat Narcolepsy

The following list of medications are in some way related to, or used in the treatment of this condition.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Govind Desai
Your provider will work with you to develop a care plan that may include one or more of these treatment options.
Medications and lifestyle modifications help to manage the symptoms.
Medication

Stimulants: Drugs that provoke the central nervous system to help individuals to remain wakeful during the day time.

Modafinil . Armodafinil


Serotonin reuptake inhibitors: Suppress REM sleep, to help ease the indications of cataplexy, hallucinations and sleep paralysis.

Fluoxetine


Tricyclic antidepressants: Drugs used to treat depression. Usually recommended in rare cases.

Protriptyline


Central nervous system depressant: It is highly effective for treating cataplexy. Usually recommended in rare cases.

Sodium oxybate

Nutrition

Foods to eat:

  • Consume a healthy balanced diet with fresh fruit and vegetables. Intake of moderate quantities of poly-unsaturated fatty acids may be helpful (soy oil, castor bean oil or sunflower oil).

Foods to avoid:

  • NA

Specialist to consult

Somnologist
Specializes in the diagnosis and therapy of sleep disturbances and disorders.
Pulmonologist
Specializes in diagnosing and treating conditions that affect the respiratory system.

Preparing For Your Appointment

  • Your doctor may make a preliminary diagnosis of narcolepsy based on your excessive daytime sleepiness and sudden loss of muscle tone (cataplexy). After an initial diagnosis, your doctor may refer you to a sleep specialist for further evaluation. Formal diagnosis requires staying overnigh…
See more on mayoclinic.org

Medications to Treat Narcolepsy

  • There is no cure for narcolepsy, but medications and lifestyle modifications can help you manage the symptoms.
See more on mayoclinic.org

Lifestyle Changes

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
See more on mayoclinic.org

Master Sources List For Narcolepsy

  • Dealing with narcolepsy can be challenging. Making adjustments in your daily schedule may help. Consider these tips: 1. Talk about it. Tell your employer or teachers about your condition and work with them to find ways to accommodate your needs. This may include taking naps during the day, breaking up monotonous tasks, recording meetings or classes, standing during meetings or lect…
See more on mayoclinic.org

Resources

  • You're likely to start by seeing your family doctor. However, in some cases when you call to set up an appointment, you may be referred to a sleep specialist. Here's some information to help you prepare for your appointment.
See more on mayoclinic.org

What Is Narcolepsy?

  • There are several medications that can combat and help reduce the effects of narcolepsy. Typically, these medications fall into two categories: stimulants that promote alertness and wakefulness; and anti-depressants and sedatives that help ensure a more regulated sleep, treat cataplexy, and can decrease overall anxiety. One of the most common pharm...
See more on sleepassociation.org

Types

  • Because narcolepsy is a chronic lifelong condition with a wide range of different symptoms andcauses, it is important to seek medical help to determine the right combination of medication and lifestyle adjustments. Besides medications, there are several ways people can adapt their lifestyle to reduce the effects of narcolepsy. Some of the key lifestyle changes that can help alle…
See more on sleepassociation.org

How Common Is Narcolepsy?

Symptoms

What Are The Effects of Narcolepsy?

Causes

Diagnosis

Treatments

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