What is the initial treatment for TB?
Drug therapy For initial empiric treatment of TB, start patients on a 4-drug regimen: isoniazid, rifampin, pyrazinamide, and either ethambutol or streptomycin. Once the TB isolate is known to be fully susceptible, ethambutol (or streptomycin, if it is used as a fourth drug) can be discontinued.
What is the most common treatment for active TB?
The most common treatment for active TB is isoniazid INH in combination with three other drugs—rifampin, pyrazinamide and ethambutol. You may begin to feel better only a few weeks after starting to take the drugs but treating TB takes much longer than other bacterial infections.
What are the 4 first line drugs for the treatment of TB?
TB can be treated effectively by using first line drugs (FLD) isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), ethambutol (EMB) and streptomycin (SM).
What is the minimum period of TB treatment?
Duration of treatment with the current first-line anti-TB drugs is a minimum of 6 months. Reducing the duration of the treatment from six to two months or less could result in significant increase of adherence to treatment and cost reduction.
What pharmacologic therapies and dosing strategies are available for the treatment of active pulmonary tuberculosis?
Dosing recommendations for capreomycin, streptomycin, kanamycin, and amikacin are the same. These agents are administered 5–7 days each week at a dose of 15 mg/kg/day (maximum 1 g/day) for the first 2–4 months of therapy in patients with normal renal function.
Which of the following is first-line drug used in tuberculosis?
First-line agents for treatment of active TB consist of isoniazid, a rifamycin (rifampin or [less frequently] either rifapentine or rifabutin), pyrazinamide, and ethambutol; in addition, moxifloxacin is a first-line agent when administered in combination with isoniazid, rifapentine, and pyrazinamide [6].
What is the treatment of pulmonary tuberculosis?
Pulmonary TB The usual treatment is: 2 antibiotics (isoniazid and rifampicin) for 6 months. 2 additional antibiotics (pyrazinamide and ethambutol) for the first 2 months of the 6-month treatment period.
WHO TB treatment regimen?
The preferred regimen for treating adults with TB remains a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 months of INH and RIF.
What are the first-line and second-line drugs for treatment of tuberculosis?
Grouping of drugsDrugs line categoryFirst-line anti-tuberculosis drugsGroup 1Isoniazid, rifampicin, ethambutol, pyrazinamideSecond-line anti-tuberculosis drugsGroup 2Moxifloxacin, high dose levofloxacin (fluoroquinolones)4 more rows•Oct 14, 2016
How long is the standard regimen treatment for TB?
RIPE regimens for treating TB disease have an intensive phase of 2 months, followed by a continuation phase of either 4 or 7 months (total of 6 to 9 months for treatment).
Which is a standard regimen for pulmonary H mono poly DR TB patient?
1. Patients with isoniazid mono-resistance. Patients diagnosed with isoniazid mono-resistance (or resistance to isoniazid and streptomycin only) are often treated with six to nine months of rifampicin, ethambutol and pyrazinamide (5,10).
How many weeks of antibiotics are you prescribed for TB?
With the proper treatment, tuberculosis (TB, for short) is almost always curable. Doctors prescribe antibiotics to kill the bacteria that cause it. You'll need to take them for 6 to 9 months.