Treatment FAQ

what is the best treatment for childood leukemia

by Nils Kulas Published 2 years ago Updated 2 years ago
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The main treatment for most childhood leukemias is chemotherapy. For some children with higher risk leukemias, high-dose chemotherapy may be given along with a stem cell transplant. Other treatments might also be used in special circumstances.

What other types of treatment are used for childhood leukemia?

Pediatric Leukemia: Chemotherapy, Radiation, and Bone Marrow Transplants MSK Kids offers all of the treatments available for pediatric leukemia. Learn what you and your child can expect. Pediatric Leukemia: CAR T Cell Therapy for Children, Teens, and Young Adults Read about chimeric antigen receptor (CAR) T cell therapy, an innovative form of immunotherapy at MSK …

Is there a cure for childhood leukemia?

 · Children with ALL should have their treatment planned by a team of doctors who are experts in treating childhood leukemia. The treatment of childhood ALL usually has three phases. Four types of standard treatment are used: Chemotherapy ; Radiation therapy Chemotherapy with stem cell transplant; Targeted therapy ; Treatment is given to kill leukemia …

How to prevent leukemia naturally in children?

Chemotherapy is the main treatment for childhood leukemia. Your child will get anticancer drugs by mouth, or into a vein or the spinal fluid. To keep leukemia from returning, there may be...

What is the expected lifespan of a child with leukemia?

Treatment for newly diagnosed childhood AML patients typically focuses on chemotherapy. Stem cell transplantation is also a treatment for AML. It can be an initial treatment for patients with particularly aggressive and hard-to-treat types of the disease.

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What is the most curable type of childhood leukemia?

Acute lymphoblastic/lymphocytic leukemia (ALL) is the most common form seen in children, per the ACS. It has a high cure rate.

Can you be cured from childhood leukemia?

With the proper treatment, the outlook for kids and teens with leukemia is quite good. Most childhood leukemias have very high remission rates, with some up to 90%. Remission means that doctors see no cancer cells in the body. Most kids are cured of the disease.

How long does childhood leukemia treatment last?

The entire length of treatment is typically about 2 to 3 years, with the most intense treatment in the first few months. Children with ALL are typically classified by risk group to make sure that the correct types and doses of drugs are given. Treatment may be more or less intense, depending on the risk group.

What is the survival rate of a child with leukemia?

Childhood leukemia is often pointed to as childhood cancer research's success story. Just 60 years ago, almost no child with leukemia survived more than a few years, but today, thanks to new discoveries and advances in treatment, 90% of children with the most common type of leukemia will survive.

How long do childhood leukemia survivors live?

Survivors of childhood cancer are living longer. Childhood cancer survivorship has improved dramatically over the past 50 years as new therapies have been discovered. Today, more than 80 percent of children and adolescents diagnosed with cancer can expect to live five years or more.

How many rounds of chemo is childhood leukemia?

Usually, there are three to four cycles of re-induction and consolidation or intensification chemotherapy. During these cycles, chemotherapy drugs are given for several days at a time, requiring that your child stay in the hospital during this treatment.

What type of leukemia is curable?

While it is similar in many ways to the other subtypes, APL is distinctive and has a very specific treatment regime. Treatment outcomes for APL are very good, and it is considered the most curable type of leukemia.

What are the side effects of childhood leukemia?

Children treated for leukemia or lymphoma may be at risk for fatigue, growth delays, thyroid dysfunction, hearing loss and the development of a secondary cancer. Children may also become infertile.

What gender is most affected by leukemia?

Leukemia is more common in men than in women, and more common in Caucasians than in African-Americans. Although leukemia is rare in children, of the children or teens who develop any type of cancer, 30% will develop some form of leukemia.

What is the most common age for childhood leukemia?

ALL is most common in early childhood, peaking between 2 and 5 years of age. AML tends to be more spread out across the childhood years, but it's slightly more common during the first 2 years of life and during the teenage years.

Why do kids get leukemia?

The exact cause of most childhood leukemias is not known. Most children with leukemia do not have any known risk factors. Still, scientists have learned that certain changes in the DNA inside normal bone marrow cells can cause them to grow out of control and become leukemia cells.

Does childhood leukemia come back?

For the most common types of leukemia in children (ALL and AML), if the leukemia does come back, it is most often while the child is still being treated or within a year or so after finishing treatment. It is unusual for ALL or AML to return if there are no signs of the disease within the next 2 years.

How to tell if a child has leukemia?

Some children are critically ill when they are first diagnosed with leukemia. For example: 1 They might have a shortage of normal white blood cells, which might lead to very serious infections. 2 They might have low levels of platelets or clotting factors in the blood, which can cause severe bleeding. 3 They might not have enough red blood cells, which can lower the amount of oxygen getting to body tissues and put a tremendous strain on the heart. 4 If they have too many (leukemic) white blood cells in the blood, it can slow down the circulation (known as leukostasis ). This can lead to serious problems in the brain, heart, or lungs. It might also cause bleeding or blood clotting inside the body. This is not common, but when it happens it needs to be treated right away.

Can leukemia cause bleeding?

This can lead to serious problems in the brain, heart, or lungs. It might also cause bleeding or blood clotting inside the body. This is not common, but when it happens it needs to be treated right away. These problems must often be addressed before treatment of the leukemia can begin.

Can a shortage of white blood cells cause bleeding?

They might have a shortage of normal white blood cells, which might lead to very serious infections. They might have low levels of platelets or clotting factors in the blood, which can cause severe bleeding.

What happens if you don't have enough red blood cells?

They might not have enough red blood cells, which can lower the amount of oxygen getting to body tissues and put a tremendous strain on the heart. If they have too many (leukemic) white blood cells in the blood, it can slow down the circulation (known as leukostasis ).

What is childhood leukemia?

Childhood acute lymphoblastic leukemia (also called ALL or acute lymphocytic leukemia) is a cancer of the blood and bone marrow. This type of cancer usually gets worse quickly if it is not treated. Enlarge. Anatomy of the bone. The bone is made up of compact bone, spongy bone, and bone marrow.

Who is the doctor who treats leukemia?

Treatment will be overseen by a pediatric oncologist, a doctor who specializes in treating children with cancer. The pediatric oncologist works with other pediatric health professionals who are experts in treating children with leukemia and who specialize in certain areas of medicine.

What is the disease that affects the white blood cells?

Childhood acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many immature lymphocytes (a type of white blood cell). Leukemia may affect red blood cells, white blood cells, and platelets. Past treatment for cancer and certain genetic conditions affect the risk of having childhood ALL.

Can leukemia cause bruising?

Leukemia may affect red blood cells, white blood cells, and platelets. Past treatment for cancer and certain genetic conditions affect the risk of having childhood ALL. Signs of childhood ALL include fever and bruising. Tests that examine the blood and bone marrow are used to diagnose childhood ALL.

What is the anatomy of a bone?

Anatomy of the bone. The bone is made up of compact bone, spongy bone, and bone marrow. Compact bone makes up the outer layer of the bone. Spongy bone is found mostly at the ends of bones and contains red marrow. Bone marrow is found in the center of most bones and has many blood vessels.

Where is the spongy bone found?

Spongy bone is found mostly at the ends of bones and contains red marrow. Bone marrow is found in the center of most bones and has many blood vessels. There are two types of bone marrow: red and yellow. Red marrow contains blood stem cells that can become red blood cells, white blood cells, or platelets.

What is the most common type of cancer in children?

Bone marrow is found in the center of most bones and has many blood vessels. There are two types of bone marrow: red and yellow. Red marrow contains blood stem cells that can become red blood cells, white blood cells, or platelets. Yellow marrow is made mostly of fat. ALL is the most common type of cancer in children.

What is the treatment for leukemia?

Chemotherapy. Chemotherapy is the major form of treatment for leukemia. This drug treatment uses chemicals to kill leukemia cells. Depending on the type of leukemia you have, you may receive a single drug or a combination of drugs. These drugs may come in a pill form, or they may be injected directly into a vein.

Can leukemia be devastating?

A diagnosis of leukemia may be devastating — especially for the family of a newly diagnosed child. With time you'll find ways to cope with the distress and uncertainty of cancer. Until then, you may find it helps to: Learn enough about leukemia to make decisions about your care.

Can leukemia be detected in blood?

A blood test may also show the presence of leukemia cells, though not all types of leukemia cause the leukemia cells to circula te in the blood. Sometimes the leukemia cells stay in the bone marrow. Bone marrow test. Your doctor may recommend a procedure to remove a sample of bone marrow from your hipbone.

How is bone marrow removed?

The bone marrow is removed using a long, thin needle. The sample is sent to a laboratory to look for leukemia cells. Specialized tests of your leukemia cells may reveal certain characteristics that are used to determine your treatment options.

What is targeted therapy?

Targeted therapy. Targeted drug treatment s focus on specific abnormalities present within cancer cells. By blocking these abnormalities, targeted drug treatments can cause cancer cells to die. Your leukemia cells will be tested to see if targeted therapy may be helpful for you. Radiation therapy.

What is the treatment for bone marrow transplant?

Radiation therapy may be used to prepare for a bone marrow transplant. Bone marrow transplant. A bone marrow transplant, also called a stem cell transplant, helps reestablish healthy stem cells by replacing unhealthy bone marrow with leukemia-free stem cells that will regenerate healthy bone marrow.

Can you use your own stem cells?

You may receive stem cells from a donor or you may be able to use your own stem cells. Immunotherapy. Immunotherapy uses your immune system to fight cancer. Your body's disease-fighting immune system may not attack your cancer because the cancer cells produce proteins that help them hide from the immune system cells.

How to treat leukemia in children?

Chemotherapy is the main treatment for childhood leukemia. Your child will get anticancer drugs by mouth, or into a vein or the spinal fluid. To keep leukemia from returning, there may be maintenance therapy in cycles over a period of 2 or 3 years. Sometimes, targeted therapy is also used.

Can leukemia be treated?

They quickly travel through the bloodstream and crowd out healthy cells. This raises the body's chances of infection and other problems. As tough as it is for a child to have cancer, it 's good to know that most children and teens with childhood leukemia can be successfully treated.

Can children get leukemia?

Keep in mind, though, that having one of these things does not necessarily mean a child will get leukemia. In fact, most children with leukemia don' t have any known risk factors.

What is the most common type of childhood leukemia?

ALL accounts for 3 out of every 4 cases of childhood leukemia. Acute myelogenous leukemia (AML). AML is the next most common type of childhood leukemia. Hybrid or mixed lineage leukemia.

Is AML a childhood leukemia?

Acute myelogenous leukemia ( AML). AML is the next most common type of childhood leukemia. Hybrid or mixed lineage leukemia. This is a rare leukemia with features of both ALL and AML. Chronic myelogenous leukemia (CML). CML is rare in children. Chronic lymphocytic leukemia (CLL). CLL is very rare in children.

Is childhood leukemia acute or chronic?

This is a rare type that is neither chronic nor acute and happens most often in children under age 4. Symptoms of Childhood Leukemia. Symptoms of leukemia often prompt a visit to the doctor. This is a good thing, because it means the disease may be found earlier than it otherwise would.

How to diagnose childhood leukemia?

Diagnosing Childhood Leukemia. To diagnose childhood leukemia, the doctor will take a thorough medical history and do a physical exam. Tests are used to diagnose childhood leukemia as well as classify its type. Initial tests may include: Blood tests to measure the number of blood cells and see how they appear.

What percentage of children have acute lymphoblastic leukemia?

Acute Lymphoblastic Leukemia. Approximately 80 percent of childhood leukemias are classified as acute lymphoblastic leukemia, commonly known as ALL. In children with this condition, the bone marrow creates too many lymphoblasts, a type of immature white blood cell.

Is CML rare in children?

Chronic leukemias are rare in children. Chronic myelogenous leukemia, commonly known as CML, is a cancer of the bone marrow that accounts for just 2 percent of all childhood leukemias.

What is bone marrow?

Opens in a new tab Twitter. Opens in a new tab. Bone marrow is the tissue within bones that produces the body’s blood cells. These cells include healthy white blood cells that prevent infection, red blood cells that carry oxygen to the organs, and platelets that help the blood to clot.

What is the name of the cancer that begins in immature white blood cells?

Acute Myeloid Leukemia. Childhood acute myeloid leukemia, commonly known as AML, is a cancer of the blood and bone marrow that begins in immature white blood cells called myeloblasts that are located within bone marrow. Myeloblasts normally grow to become one of three types of mature blood cells: red or white blood cells or platelets.

What is the rarest cancer in children?

Chronic Myelogenous Leukemia. Chronic leukemias are rare in children. Chronic myelogenous leukemia, commonly known as CML, is a cancer of the bone marrow that accounts for just 2 percent of all childhood leukemias.

What is the cancer of the bone marrow called?

Chronic myelogenous leukemia, commonly known as CML, is a cancer of the bone marrow that accounts for just 2 percent of all childhood leukemias. Most children with chronic myelogenous leukemia have an abnormal gene called BCR-ABL in the cancer cells that’s created by a translocation, or switching, of chromosomes.

What is the tissue that produces blood cells?

Bone marrow is the tissue within bones that produces the body’s blood cells. These cells include healthy white blood cells that prevent infection, red blood cells that carry oxygen to the organs, and platelets that help the blood to clot. In childhood leukemia, the bone marrow produces abnormal white blood cells that crowd out healthy blood cells, ...

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Diagnosis

Treatment

  • Treatment for your leukemia depends on many factors. Your doctor determines your leukemia treatment options based on your age and overall health, the type of leukemia you have, and whether it has spread to other parts of your body, including the central nervous system. Common treatments used to fight leukemia include: 1. Chemotherapy. Chemotherapy ...
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Clinical Trials

  • Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.
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Coping and Support

  • A diagnosis of leukemia may be devastating — especially for the family of a newly diagnosed child. With time you'll find ways to cope with the distress and uncertainty of cancer. Until then, you may find it helps to: 1. Learn enough about leukemia to make decisions about your care. Ask your doctor about your leukemia, including your treatment options and, if you like, your prognosis. As …
See more on mayoclinic.org

Preparing For Your Appointment

  • Start by seeing your family doctor if you have signs or symptoms that worry you. If your doctor suspects you have leukemia, you may be referred to a doctor who specializes in diseases of the blood and bone marrow (hematologist). Because appointments can be brief, and because there's often a lot of information to discuss, it's a good idea to be prepared. Here's some information to …
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