Treatment FAQ

what is the best medical treatment for colon cancer

by Mariela Cummerata Published 2 years ago Updated 2 years ago
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Surgery. The treatment of choice for colon cancer is surgical resection, which involves removing the cancer through surgery. Surgery is performed to remove the cancer completely and reconstruct the bowel, if possible, so your postoperative bowel function is normal or near normal.

What is the most definitive treatment for colon cancer?

Surgery is the most effective way to treat colorectal cancer. Radiation therapy is most effective as an additional or adjuvant therapy either before or after surgery. It reduces the chance of cancer spread or recurrence. Doctors do not normally use radiation as the only "definitive" treatment for colorectal cancer.

Where is the best treatment for colon cancer?

Mayo Clinic doctors are highly respected for their expertise in diagnosis and treatment of colon cancer. Mayo Clinic doctors care for more than 3,500 people with colon cancer each year. Nationally recognized expertise.Jun 11, 2021

Can colon cancer be cured with medicine?

Colorectal cancer can also be treated using drugs, which can be given by mouth or directly into the bloodstream. These are called systemic treatments because they can reach cancer cells throughout almost all the body.

How successful is treatment for colon cancer?

Cancer of the colon is a highly treatable and often curable disease when localized to the bowel. Surgery is the primary form of treatment and results in cure in approximately 50% of the patients. Recurrence following surgery is a major problem and is often the ultimate cause of death.Jan 21, 2022

What's the survival rate of colon cancer?

For colon cancer, the overall 5-year survival rate for people is 64%. If the cancer is diagnosed at a localized stage, the survival rate is 91%. If the cancer has spread to surrounding tissues or organs and/or the regional lymph nodes, the 5-year survival rate is 72%.

What stage of colon cancer requires chemo?

Most people with stage IV cancer will get chemo and/or targeted therapies to control the cancer. Some of the most commonly used regimens include: FOLFOX: leucovorin, 5-FU, and oxaliplatin (Eloxatin) FOLFIRI: leucovorin, 5-FU, and irinotecan (Camptosar)Jun 29, 2020

Can colon cancer be cured without surgery?

The study authors said that the type of patients who would most likely do well without immediate surgery are the up to 50 percent of stage I patients whose tumors typically disappear altogether following initial chemotherapy/radiation treatment.Jan 12, 2015

How fast does colon cancer spread?

How fast does colon cancer spread? Colorectal cancer tends to spread to the liver and lungs 2 years after initial cancer surgery. A 2018 study looked at Swedish people with colorectal cancer.

Why do people get colon cancer?

The exact cause of colorectal cancer is not known, but certain risk factors are strongly linked to the disease, including diet, tobacco smoking and heavy alcohol use. Also, people with certain hereditary cancer syndromes or a family history of colorectal cancer have a high risk of developing the disease.Mar 16, 2022

Can you live a long life after colon cancer?

Myth: Most of the time, when you are diagnosed with colon cancer, it is already spreading to other parts of your body. Fact: This is simply not true. The majority of patients diagnosed with colon cancer can be treated and will go on to live normal lives.Jun 17, 2015

Where is the first place colon cancer spreads?

While colon cancer can travel throughout the body, there are specific areas where it is more likely to spread. The most common include the liver and lungs, as well as the brain, distant lymph nodes and peritoneum (membrane that lines the abdominal cavity).

Can colon cancer be cured permanently?

If the colorectal cancer has spread only to the liver and if surgery is possible—either before or after chemotherapy—there is a chance of complete cure. Even when curing the cancer is not possible, surgery may add months or even years to a person's life.

Can colon cancer be treated with surgery?

If your cancer is very advanced or your overall health very poor, your surgeon may recommend an operation to relieve a blockage of your colon or other conditions in order to improve your symptoms. This surgery isn't done to cure cancer, but instead to relieve signs and symptoms, such as a blockage, bleeding or pain.

What is the procedure to remove cancer from the colon?

If the cancer has grown into or through your colon, your surgeon may recommend: Partial colectomy. During this procedure, the surgeon removes the part of your colon that contains the cancer, along with a margin of normal tissue on either side of the cancer.

Can you get colon cancer at the earliest stage?

Doctors recommend certain screening tests for healthy people with no signs or symptoms in order to look for signs of colon cancer or noncancerous colon polyps. Finding colon cancer at its earliest stage provides the greatest chance for a cure. Screening has been shown to reduce your risk of dying of colon cancer.

What is the procedure to check for colon cancer?

Colonoscopy. During a colonoscopy , the doctor inserts a colonoscope into your rectum to check for abnormalities in your entire colon. If your signs and symptoms indicate that you could have colon cancer, your doctor may recommend one or more tests and procedures, including:

What is the earliest stage of colon cancer?

At its earliest stage (stage 0), colon cancer is limited to the inner lining of your colon. As colon cancer progresses, it can grow through your colon and extend to nearby structures. The most advanced stage of colon cancer (stage IV) indicates cancer has spread to other areas of the body, such as the liver or lungs.

What tests are needed for colon cancer?

Staging helps determine what treatments are most appropriate for you. Staging tests may include imaging procedures such as abdominal, pelvic and chest CT scans.

How does chemotherapy help with colon cancer?

Chemotherapy uses drugs to destroy cancer cells. Chemotherapy for colon cancer is usually given after surgery if the cancer is larger or has spread to the lymph nodes. In this way, chemotherapy may kill any cancer cells that remain in the body and help reduce the risk of cancer recurrence.

What is the most common treatment for colon cancer?

Approximately 39 percent of colon cancer patients have localized disease, according to the American Society of Clinical Oncology. The most common treatment for early stage colon cancer is surgery. Some patients with early stage disease may also receive chemotherapy after surgery. For patients with localized colon cancer, ...

Can colon cancer be treated with chemotherapy?

If colon cancer has spread to nearby lymph nodes but not to other parts of the body, surgery may be used followed by chemotherapy. When the disease has spread to distant sites, chemotherapy may be used as the primary treatment, especially if surgery is unlikely to cure the cancer.

What kind of doctors treat colon cancer?

If you have colon cancer, your treatment team will include medical oncologists, surgeons and radiation oncologists. These specialists will work together to develop the best treatment plan for your condition.

What percentage of colon cancer patients have localized disease?

Some patients with early stage disease may also receive chemotherapy after surgery. For patients with localized colon cancer, the five-year survival rate is 90 percent.

What is the survival rate of colon cancer?

It may also spread to the lungs, brain, peritoneum (the lining of the abdominal cavity) and/or distant lymph nodes. For patients with this type of late stage disease, the five-year survival rate is 14 percent.

Where does colon cancer spread?

When colon cancer metastasizes (spreads), it usually appears in the liver. It may also spread to the lungs, brain, peritoneum (the lining of the abdominal cavity) and/or distant lymph nodes. For patients with this type of late stage disease, the five-year survival rate is 14 percent.

What is the treatment for gastrointestinal cancer?

Other treatment options for late stage gastrointestinal cancers may include cytoreductive (debulking) surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).

What is the most common treatment for colon cancer?

Surgery (removing the cancer in an operation) is the most common treatment for all stages of colon cancer. A doctor may remove the cancer using one of the following types of surgery:

What is done after colon cancer diagnosis?

After colon cancer has been diagnosed, tests are done to find out if cancer cells have spread within the colon or to other parts of the body.

What is colon cancer?

Key Points. Colon cancer is a disease in which malignant (cancer) cells form in the tissues of the colon. Health history affects the risk of developing colon cancer. Signs of colon cancer include blood in the stool or a change in bowel habits. Tests that examine the colon and rectum are used to diagnose colon cancer.

What are the risk factors for colon cancer?

Risk factors for colorectal cancer include the following: Having a family history of colon or rectal cancer in a first-degree relative (parent, sibling, or child). Having a personal history of cancer of the colon, rectum, or ovary.

How do you know if you have colon cancer?

Signs of colon cancer include blood in the stool or a change in bowel habits. These and other signs and symptoms may be caused by colon cancer or by other conditions. Check with your doctor if you have any of the following: A change in bowel habits. Blood (either bright red or very dark) in the stool.

What is the process used to find out if cancer has spread within the colon or to other parts of the body?

The process used to find out if cancer has spread within the colon or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment.

What is it called when cancer spreads to another part of the body?

When cancer spreads to another part of the body, it is called metastasis . Cancer cells break away from where they began (the primary tumor) and travel through the lymph system or blood.

What is the most common treatment for colon cancer?

Surgery. Surgery to remove tumors is the most common treatment for colon cancer, especially early stage cancer that is contained in the colon. About 95 percent of stage 1 and 65 to 80 percent of stage 2 colon cancers are curable by surgery. The main goals of colon cancer surgery are to remove the cancer completely and to reconstruct ...

Is radiation therapy recommended for colon cancer?

Unlike rectal cancer, radiation therapy is not used as a primary treatment for colon cancer. The colon is not a fixed structure inside the body — the bowel naturally moves around — making it more difficult to target accurately with radiation. Radiation therapy is not recommended for stage 1 and 2 colon cancers.

How does chemo work?

Sometimes chemotherapy is given prior to surgery to shrink a tumor and reduce the extent of surgery.

When is chemo given?

Sometimes chemotherapy is given prior to surgery to shrink a tumor and reduce the extent of surgery. This is called neo-adjuvant therapy. Chemotherapy is also given when the cancer has spread beyond the scope of surgery.

What is the best treatment for stage 4 colon cancer?

Chemotherapy may be recommended for stage 4 cancers even if a patient has not undergone surgery. Some of the most common intravenous chemotherapy used to treat stage 4 colon cancer are combinations of drugs called FOLFOX and FOLFIRI. Other medicines for patients with advanced colon cancers include drugs that target tumor blood vessel growth, ...

What is immunotherapy for cancer?

Immunotherapy refers to medical treatments that harness or strengthen the body’s own immune defense system against cancer cells. Johns Hopkins researchers led the first clinical trials of one type of immunotherapy, known as immune checkpoint inhibitors, and are continuing their work through the Bloomberg~Kimmel Institute for Cancer Immunotherapy. ...

What is the treatment for cancer?

Immunotherapy refers to medical treatments that harness or strengthen the body’s own immune defense system against cancer cells. Johns Hopkins researchers led the first clinical trials of one type of immunotherapy , known as immune checkpoint inhibitors, and are continuing their work through the Bloomberg~Kimmel Institute for Cancer Immunotherapy .

How is colorectal cancer treated?

Colorectal cancer can also be treated using drugs, which can be given by mouth or directly into the bloodstream. These are called systemic treatments because they can reach cancer cells throughout almost all the body. Depending on the type of colorectal cancer, different types of drugs might be used, such as: Chemotherapy for Colorectal Cancer.

What kind of doctor treats colorectal cancer?

These doctors could include: A gastroenterologist: a doctor who treats disorders of the gastrointestinal (GI or digestive) tract. A surgical oncologist (oncologic surgeon): a doctor who uses surgery to treat cancer.

Can alternative treatments help with cancer?

Alternative treatments are used instead of a doctor’s medical treatment. Although some of these methods might be helpful in relieving symptoms or helping you feel better, many have not been proven to work. Some might even be harmful. Be sure to talk to your cancer care team about any method you are thinking about using.

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

What is the number to call for cancer treatment?

Call our National Cancer Information Center at 1-800-227-2345 and speak with one of our trained specialists. Palliative Care. Find Support Programs and Services in Your Area.

Is treatment information given here official policy of the American Cancer Society?

The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

What is a radiation oncologist?

A radiation oncologist: a doctor who treats cancer with radiation therapy. A medical oncologist: a doctor who treats cancer with medicines such as chemotherapy or targeted therapy. You might have many other specialists on your treatment team as well, including physician assistants (PAs), nurse practitioners (NPs), nurses, psychologists, ...

When do you need to get screened, and how often?

One of the deadliest cancers can be prevented or detected at a curable stage if you follow recommended screening guidelines.

Disclaimer

As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

What is the best treatment for colon cancer?

Immunotherapy. Perhaps the most recent innovation in colon cancer treatment involves immunotherapy, which uses your body’s immune system to fight cancer. For example, a colon cancer vaccine to boost immune system response to cancer is being developed. But most immunotherapies for colon cancer are still in clinical trials.

Is colon cancer a cancer?

Colorectal cancer is the third most commonly diagnosed cancer in the United States for men and women. But in recent years, new advancements in early detection and treatment of colorectal cancer (also called colon cancer) show a promising future for patients and their families. Experts provide an overview of what you can look forward to in ...

Is the death rate of colon cancer dropping?

The death rate of colorectal cancer has been dropping for decades, according to the American Cancer Society. In addition to new and improved colon cancer treatments, early detection is a big reason for this.

How long does colon cancer last?

In comparison, those with stage 1 cancer have a 5-year relative survival rate of about 90 percent. There are a number of tests available today that can help detect early signs of colon cancer or even a predisposition to developing it.

Why is colon cancer screening important?

Colon cancer screenings are important because they allow doctors to look inside your colon to see how things are doing. The American College of Physicians recommends fecal occult blood testing every 2 years, a colonoscopy every 10 years, or a sigmoidoscopy every 10 years plus FIT every 2 years if your CRC risk is greater than 3%. ...

What percentage of colon cancer is genetic?

About 5 to 10 percent of colon cancer cases are a result of a genetic mutation passed down from parents to children. DNA testing is available that can help doctors learn whether you have a higher risk for developing colon cancer.

Is robotic surgery used for cancer?

Today, robotic surgery is even being used for colorectal cancer surgery. It involves use of robotic arms to perform the surgery. This new technique is still being studied for its efficacy.

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Overview

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Colon cancer is a type of cancer that begins in the large intestine (colon). The colon is the final part of the digestive tract.Colon cancer typically affects older adults, though it can happen at any age. It usually begins as small, noncancerous (benign) clumps of cells called polyps that form on the inside of the colon. Over time som…
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  • Air Bubbles in Urine: Air bubbles in your urine (called pneumaturia) may occur if a tumor in the colon invades into the bladder.
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  • Cancer is an abnormal growth of cells that invade healthy tissue. Cancer cells can form tumors in the areas where they originate, and they can spread to other parts of the body and grow there, according to the ACS. Colorectal cancer usually begins as a polyp in the wall of the colon or the rectum. Depending on where the cancer starts, it may be called colon cancer or rectal cancer.
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Treatment

  • While a nasogastric tube may be placed temporarily to reduce swelling and remove the fluid and gas buildup of a bowel obstruction, surgery to remove the obstructing tumor or a stent placement (to open up the blocked area) is often required.
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  • Primary treatment for all stages of colon cancer is surgery to remove the cancerous and surrounding tissues. In early stages, doctors may remove cancer using instruments inserted through the anus. If the cancer is larger, surgeons may cut through the abdominal wall and remove the cancer, a small amount of healthy tissue and some lymph nodes before sewing the …
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  • Surgery is the main treatment for colorectal cancer. You may also have chemotherapy or radiation. The extent of surgery and whether you need treatment after surgery depends on: 1. Whether the cancer is in the colon or rectum. 2. The stage of the disease. The cancer's stage depends on how far the cancer has spread. Following are the stages of colorectal cancer, along …
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Signs And Symptoms

  • Signs and symptoms of colon cancer include: 1. A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool 2. Rectal bleeding or blood in your stool 3. Persistent abdominal discomfort, such as cramps, gas or pain 4. A feeling that your bowel doesn't empty completely 5. Weakness or fatigue 6. Unexplained weight lossMa…
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  • As the third leading cause of cancer-related deaths in the United States, it's important to know the symptoms of colon cancer so you can do your best to catch it early, when it's most treatable. Some include cramping belly pain, dark or bright red blood in your stool, or a change in your stool frequency, like persistent diarrhea or constipation. Whole-body symptoms like unintentional wei…
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  • Colon cancer that has reached stage 3 will likely induce symptoms that you can detect. This includes pain in the lower abdomen area, cramps, difficult bowel movements, nausea and extreme fatigue. If you experience any of these symptoms, you should consult your doctor. Anyone over 50 should be screened for colon cancer, even in the absence of symptoms. Stages 0, 1 and 2 may n…
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  • The most common symptoms of colon cancer are rectal bleeding and lower abdominal cramping. Other telltale symptoms may include a change in stool consistency, constipation, diarrhea or weight loss. Blood tests that reveal new-onset anemia can often signal the presence of a colon tumor.
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Causes

  • Doctors aren't certain what causes most colon cancers.In general, colon cancer begins when healthy cells in the colon develop changes (mutations) in their DNA. A cell's DNA contains a set of instructions that tell a cell what to do.Healthy cells grow and divide in an orderly way to keep your body functioning normally. But when a cell's DNA is damaged and becomes cancerous, cells con…
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  • The colon is shaped like a lean-to, with the ascending colon traveling up the right side of your abdomen, the transverse colon traveling horizontally across your upper abdomen, and the descending colon traveling from just under your ribs on the left, down to the rectum and anus. Change in stool shape: Thin or narrow stools, often described as ribbon- or pencil-like, may also …
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  • Are the symptoms and causes of colon cancer in people in their 30s and 40s different than the symptoms and causes of colon cancer in older people? In many cases, the exact cause of colon cancer can't be identified. Age is the most significant factor that can increase a person's risk for developing the disease. About 90 percent of people diagnosed with colon cancer are older than …
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  • There is no single cause of colon cancer, but most begin as tiny, initially harmless growths called colorectal polyps that stick out of the lining of the large intestine. Not all colorectal polyps turn into cancer, but over time a type called adenomatous polyps may become cancerous, especially if they are bigger than one centimeter (about ½ inch) in size. Doctors often recommend colonosco…
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Diagnosis

  • While many people have heard that having blood in their stools may be a sign of colon cancer, just about any change in your bowel habits is worth evaluating. While you may be anxious about the possibility of having colon cancer, early diagnosis offers you the best opportunity for treatment success. In addition, there is a possibility that something else entirely is going onsomething les…
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  • Diagnosis begins with a physical exam and discussion of your symptoms with your doctor. If colon cancer is suspected, the doctor will follow up with diagnostic tests, including blood tests, a colonoscopy and a biopsy, during which a tissue sample taken during the colonoscopy is looked at under the microscope to determine the presence of cancer cells.
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  • 1. Diverticular disease. 2. Irritable bowel syndrome. 3. Inflammatory bowel disease - e.g. Crohn's disease, ulcerative colitis. 4. Local rectal pathology - eg, haemorrhoids. 5. Anal cancer. 6. Ischaemic colitis. 7. Pneumatosis coli.
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  • Colon cancer symptoms are similar in younger and older people. Because the large majority of colon cancers occur in people older than 50, however, the disease may go undetected in those who are younger until the cancer is more advanced. Timely screening for people at high risk for colon cancer, along with prompt assessment of any worrisome symptoms, is critical to early dia…
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Prognosis

  • This lag time, which averages around five months, could result in a colon cancer spreading further and lowering the chance of a cure. While it's true that most people with these symptoms do not have colon cancer, it's never safe to assume that's the case.
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  • Around half of people diagnosed with colorectal cancer survive for at least five years after diagnosis: 1. 60% are amenable to radical surgery and 70% of these will be alive at seven years (or will have died from non-tumour-related causes). 2. Survival rates relative to age-matched groups without colorectal cancer, are now about 45% at five years after diagnosis. Beyond five years, rel…
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  • The outlook for people with colon cancer often depends on the stage at which their cancer is treated. The American Cancer Society reports that more than 90 percent of people whose cancer is found before it has spread will live at least five years, a time period commonly used to measure cancer survival rates. After colon cancer has spread, the five-year survival rate is between 44 per…
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  • The outlook for colorectal cancer depends on the stage of the disease. Nearly everyone with stage 0 cancer will survive 5 years or more. The outlook is less favorable for people with stage IV cancer.
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Prevention

  • Doctors recommend that people with an average risk of colon cancer consider colon cancer screening around age 50. But people with an increased risk, such as those with a family history of colon cancer, should consider screening sooner.Several screening options exist — each with its own benefits and drawbacks. Talk about your options with your doctor, and together you can de…
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  • Lower risk has been linked with: 1. Lifestyle: infrequent consumption of meat, matching calorie consumption to need, low dietary fat, active lifestyle, not smoking, frequent consumption of vegetables and possibly fruit, high-fibre diet. 2. Nutritional supplements and medication: vitamin supplements containing folic acid, selenium, calcium, regular use of non-steroidal anti-inflamma…
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  • The best defense against colorectal cancer is regular screening. Screening tests are designed to find polyps so they can be removed before they become cancerous. The American Cancer Society recommends that all adults begin screening at age 50. People at higher risk should begin screening earlier. You are at high risk if you: 1. Have been diagnosed with polyps before age 50. …
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  • Previous guidelines didn't address the appropriateness of colonoscopies for older adults. The new ACS guidelines recommend screenings through age 75. For people ages 76 to 85, decisions about screening should be made on an individual basis. Some considerations for screening older adults include the following: As with many other health problems, the risk of colorectal cancer increase…
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Risk Factors

  • Factors that may increase your risk of colon cancer include: 1. Older age. Colon cancer can be diagnosed at any age, but a majority of people with colon cancer are older than 50. The rates of colon cancer in people younger than 50 have been increasing, but doctors aren't sure why. 2. African-American race. African-Americans have a greater risk of colon cancer than do people of …
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  • Risk factors for colorectal cancer include: 1. Increasing age 2. Family history of colorectal cancer 3. Personal history of colorectal cancer 4. Personal history of polyps 5. Inflammatory bowel disease, including persistent ulcerative colitis and Crohn's disease 6. Sedentary lifestyle 7. Race and ethnicity (Alaska natives have the highest risk)
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Epidemiology

  • 1. Colorectal cancer is the fourth most common cancer in the UK after breast, prostate and lung cancer. 2. There were 41,804 new cases of bowel cancer registered in the UK in 2015. 3. Colorectal cancer is the second most common cause of cancer death in the UK. 4. The age-standardised incidence rates for newly diagnosed cancers in England were 670.8 per 100,000 m…
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  • Population studies show that colon cancers are occurring at increasing rates in people younger than 50. Cases in younger people now account for more than 10 percent of all colon cancers. Environmental factors, changes in diet and lifestyle, and the national trend toward obesity may be contributing to this rise. Also, younger-onset colon cancer appears to affect African-Americans …
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  • Despite the effectiveness of screening, colorectal cancer remains the second-leading cause of cancer deaths in the United States, and is expected to claim the lives of more than 50,000 people in the United States in 2018, according to the ACS. The lifetime risk of developing colorectal cancer is about 1 in 22 for men and around 1 in 24 for women.
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Stage 3

  • Colon cancer, also referred to as colorectal cancer, is the uncontrolled growth of cancer cells in the lining of the colon. The colon is part of the large intestine which also includes the rectum and the appendix. Stage 3 colon cancer as described by the American Cancer Society is broken down into three sub-stages. Stage 3a is when the cancer has grown into the submucosa of the lining a…
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  • Surgery is the main treatment for stage 3 colon cancer. Chemotherapy and radiation therapy may also be used.
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