Treatment FAQ

what is remdesivir treatment for coronavirus

by Mireille Schulist Published 2 years ago Updated 2 years ago
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Remdesivir has demonstrated in vitro activity against SARS-CoV-2. In a rhesus macaque model of SARS-CoV-2 infection, remdesivir treatment was initiated soon after inoculation; the remdesivir-treated animals had lower virus levels in the lungs and less lung damage than the control animals.

How does Remdesivir injection work to treat COVID-19?

Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body.

What are the side effects of Remdesivir?

Remdesivir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:• nausea• constipation• pain, bleeding, bruising of the skin, soreness, or swelling near the place where the medication was injected

What is Remdesivir?

Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body.

Is Remdesivir approved to treat COVID-19?

Remdesivir is a nucleotide analogue prodrug that is approved to treat COVID-19 in certain patients.Mar 2, 2022

Are long term side effects possible with the COVID-19 vaccine?

Benefits of Vaccination Outweigh the Risks Serious side effects that could cause a long-term health problem are extremely unusual following any vaccination, including COVID-19 vaccination.

Is it possible to have lingering symptoms of COVID-19?

"Some symptoms of COVID-19 linger longer than others," says Dr. Septimus. "In particular, fatigue and loss of taste and smell can persist beyond the period of contagion."While uncomfortable and/or inconvenient, Dr. Septimus adds that these lingering symptoms aren't too worrisome for most people.Jan 5, 2022

What medication can I take to reduce the symptoms of COVID-19?

In general, taking acetaminophen (Tylenol), naproxen (Aleve) ibuprofen (Advil or Motrin) can help lower fevers, help manage muscle aches and body pains and make the course of the illness a little bit more tolerable.Dec 27, 2021

Is Remdesivir approved in Europe for treatment of COVID-19?

Since July 2020, remdesivir has been conditionally approved in Europe for the treatment of coronavirus disease (COVID-19) in adults and adolescents aged 12 years and older with pneumonia who require supplemental oxygen but no invasive ventilation.Jul 6, 2021

What does COVID-19 do to the lungs?

COVID-19 can cause lung complications such as pneumonia and, in the most severe cases, acute respiratory distress syndrome, or ARDS. Sepsis, another possible complication of COVID-19, can also cause lasting harm to the lungs and other organs.Feb 28, 2022

Which drug is approved by FDA to treat COVID-19?

Veklury (Remdesivir) is an antiviral drug approved for use in adults and pediatric patients [12 years of age and older and weighing at least 40 kilograms (about 88 pounds)] for the treatment of COVID-19 requiring hospitalization.Mar 31, 2022

What is the first drug that was approved by the FDA to treat COVID-19?

Remdesivir is the first drug approved by the FDA for treatment of hospitalized COVID patients over the age of 12.Jan 25, 2022

Is the antiviral medication Paxlovid authorized for COVID-19?

On Dec 22, 2021, the US Food and Drug Administration (FDA) issued an emergency use authorisation for Pfizer's COVID-19 antiviral, Paxlovid.Jan 13, 2022

Monitoring and Adverse Effects

  • Remdesivir can cause gastrointestinal symptoms (e.g., nausea), elevated transaminase levels, an increase in prothrombin time without a change in the international normalized ratio, and hypersensitivity reactions. Liver function tests and prothrombin time tests should be performed …
See more on covid19treatmentguidelines.nih.gov

Drug-Drug Interactions

  • Currently, no clinical drug-drug interaction studies of remdesivir have been conducted. In vitro, remdesivir is a minor substrate of cytochrome P450 (CYP) 3A4 and a substrate of the drug transporters organic anion transporting polypeptide (OATP) 1B1 and P-glycoprotein. It is also an inhibitor of CYP3A4, OATP1B1, OATP1B3, and multidrug and toxin extrusion protein 1 (MATE1).…
See more on covid19treatmentguidelines.nih.gov

Considerations in Pregnancy

  • Remdesivir should not be withheld from pregnant patients if it is otherwise indicated. Pregnant patients were excluded from the clinical trials that evaluated the safety and efficacy of remdesivir for the treatment of COVID-19, but preliminary reports of remdesivir use in pregnant patients from small studies and case reports are reassuring.13 Among 86 pregnant and postpartum hospitaliz…
See more on covid19treatmentguidelines.nih.gov

Considerations in Children

  • Remdesivir is available through an FDA EUA for the treatment of COVID-19 in hospitalized pediatric patients weighing 3.5 kg to <40 kg or aged <12 years and weighing ≥3.5 kg. There are insufficient data on the safety and efficacy of using remdesivir to treat COVID-19 in hospitalized pediatric patients aged <12 years or weighing <40 kg because these populations have not been …
See more on covid19treatmentguidelines.nih.gov

Clinical Trials

  • Several clinical trials that are evaluating the use of remdesivir for the treatment of COVID-19 are currently underway or in development. Please see ClinicalTrials.govfor the latest information.
See more on covid19treatmentguidelines.nih.gov

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