Treatment FAQ

what is rai treatment

by Miss Jacky Stroman Published 2 years ago Updated 2 years ago
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Radioactive iodine
Radioactive iodine
There are 37 known isotopes of iodine (53I) from 108I to 144I; all undergo radioactive decay except 127I, which is stable. Iodine is thus a monoisotopic element. Its longest-lived radioactive isotope, 129I, has a half-life of 15.7 million years, which is far too short for it to exist as a primordial nuclide.
https://en.wikipedia.org › wiki › Isotopes_of_iodine
(RAI) is treatment for overactive thyroid
overactive thyroid
Hyperthyroidism, also called overactive thyroid, is a condition where your thyroid makes and releases high levels of thyroid hormone. This condition can make your metabolism speed up. Symptoms of hyperthyroidism include a rapid heartbeat, weight loss, increased appetite and anxiety.
https://my.clevelandclinic.org › health › 14129-hyperthyroidism
(hyperthyroidism) and certain types of thyroid cancer
. The term “radioactive” may sound frightening, but it is a safe, generally well-tolerated, and reliable treatment that targets thyroid cells so there is little exposure to the rest of your body's cells.
Sep 8, 2020

How long do you have to be in isolation after radioactive iodine?

You are also required to self isolate for 7 days after your radioiodine treatment in order to minimise the risk of contracting COVID-19 whilst there is still a large amount of radioactivity in your body. A small proportion of people with COVID-19 may become very unwell and require admission to hospital.

How quickly does RAI work?

Within 3 weeks, only traces of RAI remain in your body. However, it may take several months for the RAI to have its full effects on any remaining thyroid tissue, both cancerous and non-cancerous. This is because the radiation affects the cells gradually.Jan 18, 2017

How long does RAI treatment take?

One dose is usually enough to kill the remaining thyroid fragments and cancer cells. Radioactive iodine therapy can take anywhere from a few weeks to a few months to fully eliminate all papillary thyroid cancer cells.Aug 8, 2016

What are the side effects of radioactive iodine treatment?

Short-term side effects of RAI treatment may include: Neck tenderness and swelling. Nausea and vomiting. Swelling and tenderness of the salivary glands.Mar 14, 2019

What are the long term side effects of radioactive iodine?

Longer-term complications include recurrent sialoadenitis associated with xerostomia, mouth pain, dental caries, pulmonary fibrosis, nasolacrimal outflow obstruction, and second primary malignancies. This article summarizes the common complications of RAI and methods to prevent and manage these complications.

Can you go home after radioactive iodine treatment?

Remain in your home for the first four days. Do not hold young children or spend much time near a pregnant woman. Family members should stay about six feet or more from you. After the first two days, they may be closer for brief periods, such as a few minutes.Apr 30, 2009

How will I feel after RAI treatment?

A swollen or tender neck and feeling flushed Some people may have a feeling of tightness or swelling in their neck for a few days after treatment. This is more common if you still had a large part of your thyroid gland when you have radioactive iodine treatment. Some people also feel flushed.May 24, 2021

Does radioactive iodine shorten your life?

Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery. Quality of life is worse at 6-10 years after radioactive iodine therapy of Graves' disease compared with treatment with antithyroid drugs or surgery.

Is Rai a radiation?

Although the treatments with 131-I are generally safe, RAI produces radiation so patients must do their best to avoid radiation exposure to others, particularly to pregnant women and young children. The amount of radiation exposure markedly decreases as the distance from the patient increases.

How successful is radioactive iodine treatment?

Conclusion: Radioactive iodine treatment is an effective modality for definitive treatment of hyperthyroidism with long-term cure approaching 80%.

Which is better radioactive iodine or surgery?

Surgery for hyperthyroidism was associated with a lower risk of all-cause and cardiovascular death as compared to radioactive iodine therapy during long-term follow-up, particularly in men.

Can radioactive iodine cause other cancers?

Patients treated with radioactive iodine also have an increased risk of acute lymphocytic leukemia (ALL), stomach cancer, and salivary gland cancer.Jun 9, 2020

How to treat RAI?

For RAI therapy to be most effective, you must have a high level of thyroid-stimulating hormone (TSH or thyrotropin) in the blood. This hormone is what makes thyroid tissue (and cancer cells) take up radioactive iodine. If your thyroid has been removed, there are a couple of ways to raise TSH levels before being treated with RAI: 1 One way is to stop taking thyroid hormone pills for several weeks. This causes very low thyroid hormone levels (hypothyroidism), which makes the pituitary gland to release more TSH. This intentional hypothyroidism is temporary, but it often causes symptoms like tiredness, depression, weight gain, constipation, muscle aches, and reduced concentration. 2 Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day.

How long should I take thyrotropin before RAI?

Another way is to get an injection (shot) of thyrotropin (Thyrogen), which can make withholding thyroid hormone for a long period of time unnecessary. This drug is given daily for 2 days, followed by RAI on the 3 rd day. Most doctors also recommend that you follow a low iodine diet for 1 or 2 weeks before treatment.

What is the radiation used for thyroid cancer?

The radiation dose used here is much stronger than the one used in radioiodine scans, which are described in Tests for Thyroid Cancer. This treatment can be used to ablate (destroy) any thyroid tissue not removed by surgery or to treat some types of thyroid cancer that have spread to lymph nodes and other parts of the body.

How long after radiation therapy can you go home?

Depending on the dose of radioiodine used and where you are being treated, you might need to be in the hospital for a few days after treatment, staying in a special isolation room to prevent others from being exposed to radiation. Some people may not need to be hospitalized. Once you are allowed to go home after treatment, you will be given instructions on how to protect others from radiation exposure and how long you need to take these precautions. These instructions may vary slightly by treatment center. Be sure you understand the instructions before you leave the hospital.

Can you use rai for thyroid cancer?

Discuss your risks and benefits of RAI therapy with your doctor. Radioactive iodine therapy cannot be used to treat anaplastic (undifferentiated) and medullary thyroid carcinomas because these types of cancer do not take up iodine.

Can radiation cause irregular periods?

Radioactive iodine may also affect a woman’ s ovaries, and some women may have irregular periods for up to a year after treatment.

Does radioactive iodine help with thyroid cancer?

Radioactive iodine therapy helps people live longer if they have papillary or follicular thyroid cancer (differentiated thyroid cancer) that has spread to the neck or other body parts, and it is now standard practice in such cases. But the benefits of RAI therapy are less clear for people with small cancers of the thyroid gland ...

What is the purpose of I-131?

THYROID CANCER – Large doses of I-131 are used to destroy thyroid cancer cells (see Thyroid Cancer brochure ). This is performed after the remaining thyroid cells ( including any cancer cells) are stimulated by raising TSH levels by either withdrawing the thyroid hormone pills or by treating with recombinant human TSH.

What is the I-123 isotope used for?

I-123 is the usual isotope used to take pictures and determine the activity of the intact thyroid gland ( Thyroid Scan and Radioactive Iodine Uptake, RAIU ), since it is harmless to thyroid cells. No special radiation precautions are necessary after a thyroid scan or RAIU using I-123. I-131 can also be used to take pictures of the thyroid gland, ...

Is rai safe for X-rays?

RAI is safe to use in individuals who have had allergic reactions to seafood or X-ray contrast agents, since the reaction is to the compound containing io dine, not the iodine itself. RAI is given by mouth in pill or liquid form.

Can RAI cause thyroid cancer?

Hypothyroidism is a common side effect of RAI for hyperthyroidism and always seen after RAI for thyroid cancer. This is usually easily treated with thyroid hormone replacement (see Hypothyroidism brochure ). Some studies suggest a slight increase in thyroid cancers may be seen after RAI treatment for hyperthyroidism.

What is RAI surgery?

RAI is a procedure in which radioactive iodine is given with the intent to destroy thyroid gland tissue. There are side effects associated with this procedure (discussed below). Around 50% of patients with thyroid cancer get both thyroidectomy and RAI (6). This leaves another 50% who only get thyroidectomy.

What is the most common use of RAI?

Perhaps one of the most common uses of RAI is as a therapy to treat hyperthyroidism. As we discussed, RAI results in complete and irreversible damage to the thyroid gland. Because of this, you should consider all available options and therapies available to you before you undergo this procedure.

What is the goal of RAI?

Remember that the goal of RAI is to completely destroy your thyroid gland . This destruction of thyroid gland tissue will permanently alter thyroid hormone status in your body. After the procedure, you will be reliant upon thyroid medication for the rest of your life.

What is the treatment for thyroid cancer?

The baseline treatment recommended for thyroid cancer is thyroidectomy or complete thyroid removal. This procedure allows for nearly the complete ...

What is radioactive iodine?

Radioactive iodine (often abbreviated RAI) is a therapy used to treat hyperthyroidism and thyroid cancer. In this procedure, you are intentionally given Iodide, I-131, which emits radiation. Your body then takes up this radioactive iodine into your thyroid gland where the radiation proceeds to destroy thyroid gland tissue.

How does RAI work?

RAI works because it takes advantage of certain aspects of normal physiology. You probably already know that iodine (not the radiated version) is required for optimal thyroid hormone production. Each thyroid hormone has a specific amount of iodide in it (2, 3 or 4 moieties depending on the type of thyroid hormone).

Is RAI a definitive treatment?

It's definitive because after the procedure your thyroid gland will no longer function optimally and your hyperthyroidism will have been treated .

Pediatric Thyroid Disease

Learning why your child’s thyroid may not function correctly is a great first step in helping them understand their treatment process. When the thyroid gland doesn’t work properly, it can lead to conditions such as hypothyroidism or hyperthyroidism.

RAI and the Thyroid Gland

The thyroid gland manages how the body regulates energy and is particularly important for children as they play, learn, and develop. If your child has been diagnosed with thyroid disease, their physician may recommend radioactive iodine therapy. The thyroid gland is the only tissue in the body that absorbs iodine.

Communicating with Your Child

It is normal for children and adults alike to be nervous about receiving radiation. Undergoing RAI treatment can add stress to a patient’s care process. Patients may fear the concept of being “radioactive” or having to isolate themselves from others.

What is Radioactive Iodine Treatment?

The cells in the thyroid gland absorb iodine and use it to create hormones. This means doctors can use radioactive iodine to observe and treat the thyroid gland. There are two types of radioactive iodine: I-123 and I-131 .

Before Receiving RAI

Prior to receiving either form of RAI, your child must complete the following steps:

After RAI: Side Effects, Isolation, and Medication

Your child may experience some acute and longer-lasting side effects from the I-131:

Why is radio iodine so effective?

One of the reasons that radio-iodine treatment is so effective is because the thyroid readily takes up iodine, which is used in thyroid hormone production. To ensure that the treatment is maximised you will be asked to avoid any foods and medicines ...

What is the purpose of radioactive iodine?

The aim of the treatment is to damage and kill the cells responsible for the hyperthyroidism. Radioactive iodine and some other radioisotopes used in Nuclear Medicine are produced during the production of nuclear energy. They are a by-product or, if you like, a useful waste product.

What is RAI used for?

RAI, which has been used widely in the United States for the treatment of hyperthyroidism since the 1940s, is one of three commonly used treatments for hyperthyroidism. The other two are anti-thyroid drugs, which have been rising in popularity, and surgical treatment, which is used least often.

What is the NIH?

NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit nih.gov .

Which organ absorbs radiation?

Most of the radiation is absorbed by the thyroid gland, but other organs like the breast and stomach are also exposed during treatment. The researchers observed positive dose–response relationships between the dose absorbed by an organ and mortality from cancer at that site.

How long does it take for a RAI to fade?

The good news is that this radioactivity does fade over a short period of time (usually 5 to 7 days) but the bad news is that you need to stay under certain precautions during this time.

How to avoid weight gain after RAI?

Your best bet to AVOID weight gain after RAI is to go into your procedure with a normal weight and to maintain a healthy lifestyle both before and after. Just realize that you will always be in a 'sensitive' category and you will be more likely to gain weight compared to people with their thyroid intact. #3.

Can you survive after RAI?

You can obviously survive after RAI (otherwise they wouldn't do the procedure) but I want to teach you how to thrive afterward. And to key to getting there is to understand what happens to your body after this procedure and how it influences your thyroid function.

Does RAI cause weight gain?

Many clinical studies have also confirmed that weight gain after RAI is a real risk. The good news is that not every single person who gets RAI will necessarily gain weight. But it does increase your risk of weight gain if you have the procedure by about 2 to 3 times.

Can you gain weight after radioactive iodine treatment?

You may gain weight. This is probably not what you want to hear, especially if this is a procedure that is necessary for your health, but it's still important to know about it. You may gain weight after you undergo radioactive iodine treatment.

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