
Treating Colon Cancer with Cannabis – THC
Tetrahydrocannabinol
Tetrahydrocannabinol is one of at least 113 cannabinoids identified in cannabis. THC is the principal psychoactive constituent of cannabis. With chemical name-trans-Δ⁹-tetrahydrocannabinol, the term THC also refers to cannabinoid isomers.
Is CBD a therapeutic option for colon cancer treatment?
In vivo, TRAIL with CBD showed a significant decrease in tumor growth and an increased number of apoptotic cells. Altogether, these FOLFOX and TRAIL therapy studies suggest that CBD may be considered as a therapeutic option for CRC or, perhaps, as an adjunctive treatment to work synergistically with conventional chemotherapies.
Can CBD be used as an oncology drug?
The final step of developing CBD as an oncology drug is through extensive and well-designed clinical trials, which are urgently needed. Table 1 The effects of CBD on different cancers. Potential Cellular Targets Anti-Tumor Pathway Tumor Type ROS ER Stress Inflammation CB1 CB2 TRPV1 TRPV2 GPR55 PI3K/AKT/mTOR MAPK Autophagy Glioblastoma X X X Breast
What are the effects of cannabis on cancer cells?
Nowadays, there are many well-known cannabis cultivars, and each one has a unique composition of different compounds. Many studies have demonstrated the effects of single cannabinoids, such as THC and CBD, on inflammation and cancer cell growth (98).
Can CBD help treat gastric cancer?
In vivo, mice injected with MKN45, another gastric cancer cell line, showed slower tumor growth and smaller tumor size with CBD treatment (20 mg/kg) three times a week. Like the in vitro studies, CBD promoted apoptosis and decreased the expression of XIAP in the tumors.

Is marijuana good for the colon?
A new study in mice has suggested that tetrahydrocannabinol (THC), which is the psychoactive compound in cannabis, can help prevent colon cancer associated with ulcerative colitis. Inflammatory bowel disease (IBD) refers to a group of chronic conditions that affect the colon and small intestine.
Does smoking marijuana increase risk of colon cancer?
In the cohort studies, increased risks of lung or colorectal cancer due to marijuana smoking were not observed, but increased risks of prostate and cervical cancers among non-tobacco smokers, as well as adult-onset glioma among tobacco and non-tobacco smokers, were observed.
How is Stage 4 colon cancer treated?
Stage 4: At stage 4, the cancer has spread to other organs, such as the liver or lungs. Johns Hopkins doctors have, at times, used surgery to treat patients with stage 4 colon cancers. Radiation therapy or chemotherapy may also be necessary at this stage.
Can you take CBD oil with chemotherapy?
Anything you take while undergoing chemotherapy could have unwanted or dangerous interactions with your chemo regimen, so don't take CBD – or any other supplements or medications – without talking to your oncologist first.
How long does Nabilone stay in your system?
The effects of nabilone may last for 48 to 72 hours, and this length of time may not be the same every time you take the medication.
Can you live 10 years with stage 4 colon cancer?
A growing number of people with stage IV colon cancer live longer than 2 years. And for a small group of people with cancer that has only spread to your liver or lung, surgery might even cure it. Also remember that survival rates are based on studies that were done a few years ago.
Can you beat stage 4 colon cancer?
This is referred to as metastatic (stage IV) colorectal cancer. Cure is not possible for most patients with metastatic colorectal cancer, although some patients who have limited involvement of distant organs (particularly restricted to the liver and/or lung) can be cured with surgery.
How long do Stage 4 colon cancer patients live?
Treatment of stage IV colon cancer is mostly palliative and its median survival is reported to be approximately 9 months with best supportive care. With 5-FU/LV, median survival improved to 12 months, and with combination 5-FU/LV plus irinotecan or oxaliplatin it is reported to be between 14 and 19 months.
What happens if colon cancer spreads?
If the cancer has spread, more symptoms can present itself where the new cancer cells have grown. Colon cancer treatments will depend on the kind of cancer, its stage, the patients’ age and health status as well as other personal characteristics.
What are the causes of colon cancer?
The most common causes of cancer are age, genes, diets, lifestyle and habits. Other medical conditions have been associated with an increased risk for colon cancer: diabetes, radiation , and Crohn’s disease. During the early stage of colon cancer it’s rare to experience any symptoms.
Can colon cancer cause diarrhea?
During the early stage of colon cancer it’s rare to experience any symptoms. However when the disease progresses, the symptoms include constipation or diarrhea, rectal bleeding, blood in the stool, pain during defecation, unexplained weight loss, fatigue, iron deficiency, and irritable bowel syndrome.
Is CBD oil safe for cancer patients?
In the scientific journal Current Drug Safety, clinical review data was published concluding that CBD is “non-toxic” for healthy cells. Aside from helping to prevent the spread of cancer, patients with colon cancer and who are undergoing chemotherapy can also benefit from using cannabis.
Can colon cancer be malignant?
Sometimes, these polyps can become malignant colon cancers if they aren’t removed during colonoscopy, a procedure which examines the condition of the intestine’s inner linings.
Is CBD psychoactive?
More studies need to be conducted although this has been a huge hurdle even if CBD isn’t psychoactive because federal law states that it’s still illegal. Once there is more information on cannabis as well as the other valuable cannabinoids and their impact on colon cancer, the plant can be used to save even more lives.
Does cannabis help with nausea?
Cannabis can help treat nausea and vomiting, while certain strains can also help induce appetite to help speed up the healing process for patients. There are many anecdotal cases online of individuals who have been able to successfully treat their colon cancers in different stages using cannabis.
What is CBD oil?
It comes in many forms: oils that are dropped under the tongue, roll-ons that are applied to the skin and even solutions for vaping. Some producers extract CBD oil and add it into foods to create edible products.
What are the ingredients in cbd?
Other sorts of substances have been found in CBD products, too, such as dextromethorphan, which is an ingredient in cough medicines. Heavy metals like lead and arsenic, pesticides and mold have also been found in CBD products.
What is the medical marijuana law in Texas?
In Texas, the Compassionate Use Act allows for the use of medical marijuana for certain conditions. Originally only for intractable epilepsy, the law was expanded this year to include cancer and certain neurodegenerative conditions, such as Parkinson’s and multiple sclerosis.
Does hemp oil contain THC?
But trace amounts of THC could still end up in CBD oil.
Is hemp a psychoactive substance?
The main difference is that hemp has far less THC than a typical marijuana plant. And unlike THC, CBD is not a psychoactive agent, so there’s less possibility that it will cause the same mental confusion, drowsiness or hallucinations that often come with THC.
Does hemp have THC?
This especially affects hemp plants, which should have less than 0.3% THC levels. Finally, there have been some reports of people getting infections after using CBD and cannabis products. This is especially concerning for immunocompromised patients, who are already susceptible to bacterial and fungal infections.
Is CBD oil regulated?
But as long as CBD oil is not marketed as a medicine or a dietary supplement, producers can get around that policy. So right now, CBD oil is very unregulated. That means it’s hard to know how much CBD or THC is really in any given product.
What Is Colon Cancer?
Also called the large intestine, the colon is the last part of the digestive tract. As with other parts of the body, cancer can form in the colon. Cancer is a disease that causes cells in the body to multiply uncontrollably. It’s natural for your cells to reproduce to replenish themselves, but cancerous cells are abnormal and divide too rapidly.
Symptoms of Colon Cancer
One of the dangers of colon cancer is that it doesn’t tend to cause noticeable symptoms until it has become more advanced. The size of the tumor or tumors in your intestine, as well as their location, can affect the symptoms you experience.
Colon Cancer Statistics
Here are some vital statistics that can help build a complete picture of the severity of colon cancer today.
Conventional Treatment Options and Their Side Effects
Doctors use three primary methods to treat colon cancer: surgery, chemotherapy, and radiation.
Medical Marijuana for Colon Cancer
While the vast majority of people with colon cancer choose to treat it through conventional methods, they may also look to alternative forms of treatment to help their bodies heal and to combat both the symptoms of their cancer and the side effects of conventional treatment methods, such as chemotherapy. That is where medical marijuana comes in.
Best Methods of Marijuana Treatment
There are many ways you can administer medical cannabis for colon cancer.
Side Effects of Medical Marijuana
Marijuana is not without potential side effects, so it’s essential to be aware of those. However, with proper use, marijuana has very few potentially harmful side effects to consider, especially compared to conventional cancer treatments.
Can CBD help with cancer?
Researchers Treat Colon Cancer In Mice With CBD-Rich Extracts. Of course, research has long suggested that medical cannabis could be beneficial for cancer patients. It is often used to counter the negative effects of chemotherapy and studies suggest that the plant could serve as an effective cancer treatment in its own right.
Does cannabis help with colon cancer?
Now, a team of researchers from Italy and the UK report that cannabis extracts high in cannabidiol (CBD) can help prevent the genesis and spread of colon cancer in mice. Their study was published in Phytomedicine December 27. According to their results, a “botanical drug substance” (BDS) with high levels of cannabidiol ...
Does CBD inhibit colon cancer?
The researchers determined that this action was mediated by activation of the cells’ CB1 and CB2 receptors. Also investigated in the study was the effect of pure cannabidiol (CBD) on colon cancer. According to the data collected, pure CBD inhibited tumor growth also. Interestingly, it did so through activation of the CB1 receptors only.
Is CBD a psychoactive cannabinoid?
Cannabidiol (CBD) seems to carry less of a stigma than tetrahydrocannabinol (THC), a psychoactive cannabinoid that is credited with the “high” associated with cannabis, and shows promise as a way to treat a variety of cancers. In turn, CBD has received a great deal of attention in recent years.
Is CBD a tetrahydrocannabinol?
Cannabidiol (CBD) certainly has its benefits, but it is not alone in that regard. Tetrahydrocannabinol (THC), cannabichromene (CBC), tetrahydrocannabivarin (THCV), and the remaining cannabinoids have each been linked to a variety of therapeutic benefits in their own right. Terpenes found in cannabis are believed to improve its effectiveness as well.
