Treatment FAQ

when did induced coma become a treatment

by Adele Funk DDS Published 3 years ago Updated 2 years ago
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It was the frontline treatment for schizophrenia from the 1930s until the 1960s.

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What is medically induced coma used for?

Mar 30, 2022 · A medically induced coma uses medication to achieve a deep state of brain inactivity. It is a deep but reversible unconsciousness that doctors purposely induce to protect the brain from damage. A common name for medically induced coma is drug-induced coma, but this is often mistaken for comas caused by the inappropriate use of illegal drugs.

Can you come out of an induced coma after 72 hours?

Mar 01, 2008 · New treatment options arose following the insights derived from experimental coma and will be described below. Experimental coma Experiments to explain observed phenomena in coma started in the second half of the 19th century, although Magendie already experimented by compressing a child's spina-bifida sack (meningocele) leading to the rise of …

What is the history of experimental coma?

The current standard of care for treatment of PIH is an ice bath submersion and drug-induced coma with high doses of benzodiazepines (Musselman and Saely, 2013; Laskowski et al., 2016 ). These measures only manage the symptom of hyperthermia and do not stop the cellular mechanisms generating the heat.

Why is my critically ill loved one in an induced coma?

Generally speaking, an induced coma serves the purpose of having a critically ill Patient pain free and especially if your critically ill loved one has had major surgery, Pancreatitis, sustained a multi- trauma or is undergoing other invasive treatment such as ECMO or Intra-aortic balloon pump, an induced coma establishes comfort and generally ...

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Is a coma always medically induced?

An induced coma – also known as a medically induced coma (MIC), barbiturate-induced coma, or drug-induced coma – is a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of an anesthetic drug, often a barbiturate such as pentobarbital or thiopental....Induced comaSpecialtyneurology2 more rows

Why do they put you in a drug-induced coma?

A drug-induced coma puts a person into a deep state of unconsciousness, which allows the brain to rest and thus decreases its swelling. The decrease in swelling can result in less pressure being put on the brain, which lessens the risk of damaging effects.Nov 30, 2021

What is the survival rate of a medically induced coma?

Studies show a very high overall mortality, ranging between 76% and 89%. 5, 6, 7 Of the surviving patients, only very few recover to a good outcome. The majority of the survivors do so with permanent disorders of consciousness or severe disabilities (see Table 1).Dec 2, 2015

Can you breathe on your own in a medically induced coma?

They may be able to breathe on their own, although some people require a machine to help them breathe. Over time, the person may start to gradually regain consciousness and become more aware.

Are you in a coma when on a ventilator?

Dr. Singh: In order to intubate you and put you on a ventilator, we have to sedate you and put you in a coma. Sedation requires medications, which can affect your body in many ways.Oct 1, 2021

How serious is being put on a ventilator?

It also helps you breathe out carbon dioxide, a harmful waste gas your body needs to get rid of. Even while they help you breathe, ventilators sometimes lead to complications. These problems can result from the ventilator itself, or from things that are more likely to happen when you're on a ventilator.Aug 9, 2021

How long can you be in a coma before brain damage?

If this condition persists for more than four weeks they can be classified as being in a continuing vegetative state. If it continues for 12 months after traumatic brain injury or 6 months after non-traumatic brain injury, the person can be classed as being in a permanent vegetative state.

Can people in a coma hear you?

Can Your Loved One Hear You. During a coma, the individual is unconscious, meaning they are unable to respond to any sounds. However, the brain may still be able to pick up on sounds from loved ones. In fact, some studies suggest talking and touching a loved one while they are in a coma may help them recover.Aug 3, 2020

What is a medically induced coma?

A medically induced coma is one option doctors may use to protect the brain after serious trauma and help it heal. The ultimate effect on everyday life largely depends on the extent of brain damage from the trauma. It is possible to have lingering disability due to the underlying brain trauma.

How long does it take to get out of a coma?

In most cases, medically induced comas are only necessary for a short period of time. Doctors typically use the procedure for a couple of days or for as long as two weeks.

Why do people go into a coma?

The most common reasons for medically induced coma involve traumatic brain injuries. These brain injuries often result in significant swelling of the brain. The swelling puts pressure on the brain. This reduces blood flow and oxygen supply to the brain, which can damage brain tissue. Inducing a coma allows the brain to rest.

What are the complications of a coma?

Complications that can occur from medically induced coma include: 1 Blood clots 2 Infection, particularly pneumonia and other lung infections 3 Heart problems 4 Pressure sores and weakness from immobility 5 Vivid nightmares and hallucinations

Why is a coma not a common procedure?

Ultimately, this state helps decrease brain swelling and protects the brain from further damage. Stroke, status epilepticus, and drug overdose are other potential reasons for medically induced coma. A medically induced coma is not a common procedure. It is usually a last resort when other options for reducing brain swelling have failed.

What to expect after a coma?

What to Expect Afterwards. When doctors see improvements in a person’s condition, they will bring them out of the medically induced coma. The process is the reverse of inducing it. Doctors gradually withdraw the drugs while monitoring brain activity and other vital signs.

Can a coma be a last resort?

It is not always possible to reduce the risk of complications with medically induced coma. What’s more, it can be difficult to separate complications of medically induced coma from complications of the brain injury itself. Doctors use medically induced coma as a last resort, when the benefit outweighs the possible risks.

Where did the term "coma" come from?

The term ‘coma’, from the Greek koma, meaning deep sleep, had already been used in the Hippocratic corpus ( Epidemica) and later by Galen (second century AD). Subsequently, it was hardly used in the known literature up to the middle of the 17th century. The term is found again in Thomas Willis’ (1621–75) influential De anima brutorum (1672), where lethargy (pathological sleep, which he localized in the outer cortex), ‘coma’ (heavy sleeping), carus (deprivation of the senses) and apoplexy (into which carus could turn and which he localized in the white matter) are mentioned, the sequence indicating increasingly deeper forms of unresponsiveness. The term carus is also derived from Greek, where it can be found in the roots of several words meaning soporific or sleepy. It can still be found in the root of the term ‘carotid’. Thomas Sydenham (1624–89) mentioned the term ‘coma’ in several cases of fever (Sydenham, 1685).

When did comas become a topic of neurological textbooks?

Gradually, the subject ‘coma’ became the subject of special chapters in neurological textbooks starting in the 1940s. Biemond's Brain diseases (1946) was among the first books in which a chapter was dedicated to the clinical examination and differential diagnosis of ‘coma’. Biemond described the systematic examination of the ‘comatose’ patient. Except for the well-known phenomena on observation and examination described above, he mentioned the absence of nystagmus, emphasized the examination of brainstem reflexes, including the vestibulo-ocular reflexes and caloric stimulation tests (Biemond, 1946 ). DeJong's The neurological examination ( 1950) included a separate chapter describing the level of ‘coma’ (mentioning the nebulous term semi-coma as a ‘state of partial or relative loss of response to the environment in which the patient's consciousness may be impaired in varying degrees’). Details on cranial nerve examination emphasizing the value of eye signs in localization and a comprehensive section on differential diagnosis is present. Neurological findings in ‘comatose’ patients due to a variety of disorders were described with considerable detail, including changes during worsening of ‘coma’. How ‘coma’ could occur was briefly mentioned and specific localizations (thalamus and hypothalamus) were suggested, but he concluded that ‘there is no incontrovertible evidence, however, that one site is essential and consciousness is probably a function of the entire organism’.

What was the first book to describe the clinical examination of a coma?

Biemond's Brain diseases (1946) was among the first books in which a chapter was dedicated to the clinical examination and differential diagnosis of ‘coma’. Biemond described the systematic examination of the ‘comatose’ patient.

What is the disease of the brain caused by cold, humid phlegm?

With respect to lethargy, Boerhaave taught: ‘Lethargy … is a brain disease accompanied by loss of motion and sense, with an irrepressible need to sleep, caused by cold, humid phlegm that moistens the brain, finally leading to putrefaction, slow fever and lassitude’ (Boerhaave, 1730–5, p. 311; Koehler, 2007 ). Table 2.

When was the coma scale published?

In 1977, a landmark paper on aspects of coma following severe head injury was published, presenting a new scale for grading the level of consciousness after head trauma (Jennett and Teasdale, 1977 ). Critical evaluation of the validity of some of these clinical signs has only recently surfaced.

When were clinical cues recognized?

Up to the middle of the 19th century, disorders of sense, motion and breathing, and also changes in the patient's pulse, were recognized as clinical cues. The distinction between a structural and toxic (endogenous and exogenous) cause was recognized early.

Who said "coma" is a term for fever?

It can still be found in the root of the term ‘carotid’. Thomas Sydenham (1624–89) mentioned the term ‘coma’ in several cases of fever (Sydenham, 1685). Partly due to the methodology we applied, apoplexy and stroke are causes often encountered.

How long does a non-traumatic coma last?

In non-traumatic coma lasting for 6 hours or greater, only 15% of the patients make a meaningful recovery to be able to return to their pre-morbid state of health.45 The prognosis following anoxic coma has been described in a separate section.

Who was the British neurosurgeon who was a TBI patient?

In 1949, the British neurosurgeon Sir Hugh Cairns focused his Victor Horsley memorial lecture on disturbances of consciousness and reported on several patients with acute coma induced by TBI. 16 One patient, a young soldier, had sustained severe TBI with prolonged coma and remained hospitalized for more than 5 months.

What is the treatment for PIH?

The current standard of care for treatment of PIH is an ice bath submersion and drug-induced coma with high doses of benzodiazepines (Musselman and Saely, 2013; Laskowski et al., 2016 ). These measures only manage the symptom of hyperthermia and do not stop the cellular mechanisms generating the heat. Benzodiazepines require repeat dosing and take a significant amount of time to achieve adequate sedation ( Nobay et al., 2004 ).

What is it called when a patient cannot be aroused by a stimuli?

The neurological condition whereby a patient cannot be aroused by vigorous visual, auditory, or painful stimuli, which we call coma, seems to have been well known to the āšipu. The first two clinical stages of coma (stupor and moaning or avoidance movements) were attributed to a spirit known as alû, as in the following case in which spastic paralysis (“tense” limbs) might also be involved: “If something like a stupor continually afflicts him and his limbs are tense, his ears roar, and his mouth is ‘seized’ so that he cannot talk – hand of an evil alû ” ( Scurlock and Andersen, 2005, pp. 293, 339).

How long did it take for a soldier to recover from a TBI?

16 One patient, a young soldier, had sustained severe TBI with prolonged coma and remained hospitalized for more than 5 months. It took him several weeks to regain full consciousness, and after 5 months, he still complained of difficulty “in grasping the meaning of pictures.” When observing this gradual recovery of consciousness, Cairns noted: “We have no words to describe these states which lie between coma and full consciousness.” 16 This account can be read as an early illustration of the wide range of posttraumatic arousal disturbances. Although Cairns did not use such words as arousal, sleepiness, increased sleep need or fatigue, there is nevertheless no doubt that his patient had all these arousal disturbances at different times. After 5 months, the soldier still had some kind of mental fatigue, but whether he continued to suffer from posttraumatic sleep-wake disturbances is unknown.

What should be handled calmly in a neurologic catastrophe?

Any stress reaction in the family members that accompanies neurologic catastrophe should be handled calmly. When no improvement in the neurologic deficit is seen and the outlook for a meaningful recovery is remote, an honest effort to help parents realize the gravity of the situation should be made.

What is the GOS for traumatic brain injury?

The GOS is widely used to assess recovery after traumatic brain injury. It has five broad categories: 1 = good recovery, 2 = moderate disability, 3 = severe disability, 4 = persistent vegetative state and 5 = death. It is simple, easy to administer and has been reported to have good inter-rater agreement.

What is an induced coma?

Generally speaking, an induced coma serve s the purpose of having a critically ill Patient pain free and especially if your critically ill loved one has had major surgery , Pancreatitis, sustained a multi- trauma or is undergoing other invasive treatment such as ECMO or Intra-aortic balloon pump, an induced coma establishes comfort and generally pain is managed well and efficiently during the induced coma. Some of the drugs given in an induced coma are Morphine or Fentanyl and they are both very strong and potent pain killers (opiates) that usually take care of your loved one’s pain

Why do you need a coma?

An induced coma is generally required if your critically ill loved one. • Requires mechanical ventilation with a breathing tube, because otherwise your loved one couldn’t tolerate the breathing tube in their throat and an effective ventilation therapy would be nearly impossible to achieve.

What happens after a stroke?

After vital body functions have been regained, such as a controlled brain pressure in severe head or brain injuries or after a stroke, or after multi-trauma or after major surgery, your critically ill loved one is being brought out of the induced coma, by reducing the sedation (drugs) that your loved one is getting.

What are the drugs that are given in a coma?

Some of the drugs given in an induced coma are Morphine or Fentanyl and they are both very strong and potent pain killers (opiates) that usually take care of your loved one’s pain.

Do critically ill patients remember their stay in intensive care?

Generally, most critically ill Patients in Intensive Care don’t remember much, if anything, about their stay in Intensive Care. Having said that, many critically ill Patients report that after their stay in Intensive Care they don’t remember any details, but they do remember that Family members were talking to them, holding their hands and so forth. I therefore strongly encourage you to talk to your critically ill loved one and also to touch them, hold their hand, even if they appear to be totally unconscious!

Why do we need a medically induced coma?

Reasons for medically induced coma. Induced coma is intended to reduce the metabolic demand of the brain cells and is used to protect the brain during major neurosurgery. Medically induced coma is currently used in clinical settings as treatment for patients with high risk of brain injury either from physical trauma, ...

How long is a medical coma?

The medical coma is often required for several days. About 55% of the glucose and oxygen utilization by the brain is meant for its electrical activity and the rest for all other activities like metabolism. This is recognized by something such as an electroencephalogram (EEG), which measures electrical activity in the brain. ...

What is a drug-induced state of profound brain inactivation and unconsciousness used to treat?

Induced coma also known as a medically-induced coma or medical coma, is a drug-induced state of profound brain inactivation and unconsciousness used to treat refractory intracranial hypertension and to manage treatment-resistant epilepsy (refractory status epilepticus) 1). The state of coma is achieved by continually monitoring ...

What is the purpose of barbiturate in traumatic brain injury?

Following a traumatic brain injury, an anesthetic drug such as a barbiturate or propofol, is administered continuously to provide brain protection by decreasing the cerebral metabolism and blood flow , and thereby, intracranial hypertension 2).

Does pentobarbital affect gastric motility?

Pentobarbital also reduces gastric motility putting a patient at potential risk for transmural translocation of intestinal bacteria and sepsis from intestinal organisms 28). Altered gastric motility also makes absorption of orally-available antiepileptics less reliable and compromises nutritional status.

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