What is alosetron used to treat?
Which information is essential for the nurse to teach the patient about treatment with alosetron? Report severe constipation to the health care provider. Which category of antidiarrheals is contraindicated in patients with hypersensitivity and narrow …
Can alosetron help with IBS?
Oct 11, 2021 · Alosetron works by blocking the action of serotonin on the intestine. This reduces the cramping abdominal pain, abdominal discomfort, urgency (sudden need for a bowel movement), and diarrhea caused by IBS. Alosetron does not cure IBS and may not help every person who takes it. Alosetron is available through a restricted marketing program.
How should I take alosetron?
1. What side effects of alosetron will the nurse include in the patient teaching? Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing; swelling of your face, tongue, or thoat. Serious or fatal side effects on the stomach and intestines have occurred in some people taking alosetron. In rare cases, alosetron has caused severe constipation, or ...
What are the side effects of alosetron?
Feb 01, 2022 · Symptoms of overdose. Clumsiness, unsteadiness, trembling, or other problems with muscle control or coordination. convulsions (seizures) difficulty breathing. shakiness and unsteady walk. withdrawn or socially detached behavior. Some side effects may occur that usually do not need medical attention. These side effects may go away during ...
What is essential to teach the patient who is taking loperamide?
Take loperamide with a full glass of water. Diarrhea can cause your body to lose fluids and electrolytes. Drink plenty of liquids to keep from getting dehydrated. The loperamide chewable tablet must be chewed before swallowing.
What are the side effects of Alosetron?
Common side effects of Lotronex include:headache.stomach upset or discomfort.hemorrhoids.bloating.gas.nausea.constipation.burping with heartburn.More items...
What is Alosetron used for?
Alosetron is used to treat irritable bowel syndrome (IBS) in women who have diarrhea as their main symptom. This medicine is only used in severe cases of IBS that have not responded to other therapy. IBS is also known as irritable colon or spastic colon.
Which condition is a contraindication for loperamide treatment?
IMODIUM (loperamide hcl) is contraindicated in patients with abdominal pain in the absence of diarrhea.
Can alosetron cause constipation?
Alosetron has rarely caused serious, sometimes fatal side effects of the intestines. These effects include reduced. If you have constipation, new or worsening stomach/abdominal pain, or bloody diarrhea/stools, stop taking this medication and get medical help right away.
What type of drug is alosetron?
Alosetron is in a class of medications called 5-HT3 receptor antagonists. Alosetron works by slowing the movement of stool (bowel movements) through the intestines.
Who can take alosetron?
Lotronex (alosetron hydrochloride) is a selective serotonin 5-HT3 receptor antagonist approved for the treatment of women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have chronic IBS symptoms (generally lasting 6 months or longer), have had anatomic or biochemical abnormalities of the ...Jan 6, 2016
What are the side effects of furosemide?
This medication may cause dehydration and electrolyte imbalance. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps, weakness, unusual tiredness, confusion, severe dizziness, fainting, drowsiness, unusual dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat.
Why is alosetron only used in females?
Alosetron has not been studied in large numbers of men and is not approved or recommended for men because smaller studies showed that it had no benefit among men. Despite the caveats, alosetron represents an important step forward in the treatment of IBS.
When should you not take loperamide?
Check with your doctor before taking loperamide if you:have had an allergic reaction to loperamide or any other medicines in the past.have had diarrhoea for more than 48 hours.have HIV and your stomach becomes swollen.have liver problems.have blood in your poo and a high temperature – these can be signs of dysentery.More items...
How does loperamide affect the heart?
Higher than recommended doses of loperamide can cause serious cardiac events, including QT interval prolongation, Torsades de Pointes, other ventricular arrhythmias, cardiac arrest, syncope, and death. Consider loperamide as a possible cause of these unexplained cardiac events.Jun 7, 2016
Does loperamide cause dehydration?
Do not remove the tablet from the blister pack until just before taking. No water is needed to take this medication. Diarrhea can cause dehydration.
What is alosetron used for?
Alosetron is used to treat diarrhea, pain, cramps , and the feeling of an urgent need to have bowel movements caused by irritable bowel syndrome (IBS; a condition that causes stomach pain, bloating, constipation, and diarrhea) in women who have diarrhea as their main symptom and have not been helped by other treatments.
What are the side effects of alosetron?
Alosetron may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: 1 upset stomach 2 swelling in the stomach area 3 hemorrhoids
Does alosetron cause constipation?
Alosetron may cause serious gastrointestinal (GI; affecting the stomach or intestines) side effects including ischemic colitis (decreased blood flow to the bowels) and severe constipation that may need to be treated in a hospital and may rarely cause death. Tell your doctor if you are taking any of the following medications: antihistamines;
Can you take alosetron more often than prescribed?
Take alosetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Your doctor will probably start you on a low dose of alosetron.
Can you take Alosetron again?
Once you have stopped taking alosetron because of these symptoms, do not start taking it again unless your doctor tells you that you should. Only certain doctors who are registered with the company that makes alosetron and who are aware of the possible side effects can write prescriptions for this medication.
How does Alosetron work?
IBS is also known as irritable colon or spastic colon. IBS may be caused by a chemical called serotonin, which causes your intestinal system to be overactive. Alosetron works by blocking the action of serotonin on the intestine. This reduces the cramping abdominal pain, abdominal discomfort, urgency (sudden need for a bowel movement), and diarrhea caused by IBS. Alosetron does not cure IBS and may not help every person who takes it.
How important is it to check your progress with a doctor?
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
Is alosetron safe for children?
Appropriate studies have not been performed on the relationship of age to the effects of alosetron in the pediatric population. Safety and efficacy have not been established. Because of alosetron's risk of serious side effects, use in children is not recommended.
Does alosetron cause constipation?
Infrequent but serious gastrointestinal adverse reactions have been reported with alosetron hydrochloride, including ischemic colitis and serious complications of constipation, that resulted in hospitalization, blood transfusion, surgery, and death. Alosetron hydrochloride is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have not responded adequately to conventional therapy. Immediately discontinue alosetron hydrochloride in patients who develop constipation or symptoms of ischemic colitis. Do not resume in patients who develop ischemic colitis. If constipation resolves, resume alosetron hydrochloride only on the advice of treating prescriber .
Can you change the dose of alosetron?
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of alosetron. If your dose is different, do not change it unless your doctor tells you to do so.
Medical uses
Administration
- Alosetron comes as a tablet to take by mouth. It is usually taken twice a day with or without food. Take alosetron at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take alosetron exactly as directed. Do not take more or less o...
Treatment
- Your doctor will probably start you on a low dose of alosetron. Your doctor will want to talk to you after you have taken the low dose for 4 weeks. If your symptoms are not controlled but you are not experiencing serious side effects of alosetron, your doctor may increase your dose. If you take the increased dose for 4 weeks and your symptoms are still not controlled, alosetron is not likel…
Results
- Alosetron may control IBS but will not cure it. If alosetron helps you and you stop taking it, your IBS symptoms may return within 1 or 2 weeks.
Contraindications
- Alosetron should not be prescribed for other uses; ask your doctor or pharmacist for more information.
Risks
- Some side effects can be serious. If you experience any of the symptoms listed in the IMPORTANT WARNING section, call your doctor immediately. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or b…
Prevention
- Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toi…
Preparation
- It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.