Treatment FAQ

what is active line of treatment

by Kory Quigley Published 3 years ago Updated 2 years ago

Active treatment means any therapeutic intervention with the aim of prolonging the Insured ’s life, including but not limited to radiotherapy, chemotherapy, targeted therapy, hormonal therapy, immunotherapy, proton therapy and surgery for a Covered Cancer, including any complications thereof (if applicable).

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What is active treatment?

Nov 18, 2021 · Similarly, IRDAI-mandated Corona Kavach will pay home-treatment claims, but only if there is a “continuous, active line of treatment with …

What is the difference between control and active treatment?

active treatment treatment directed immediately to the cure of the disease or injury. causal treatment treatment directed against the cause of a disease. conservative treatment treatment designed to avoid radical medical therapeutic measures or operative procedures.

What are the lines of treatment for cancer?

Active treatment means a remedial activity that is not natural attenuation or monitoring but is conducted in situ. Active treatment includes use of biological or chemical agents to aug- ment remediation of contamination.

What is line of therapy and why is it important?

Active treatments treat the underlying cause of the bone marrow failure. These drugs are typically approved by the U.S. Food and Drug Administration (FDA) to treat a specific disease. It is important to note that active treatments do not cure the disease. The only potential cure for a bone marrow failure disease is a bone marrow/stem cell transplant.

What is the importance of defining lines of treatment?

An example of the importance of defining lines of treatment is a 2019 study that compared different second-line treatments for lung cancer. Since there are a number of different options, and many studies look at the effectiveness of first line therapies, this can give important information to oncologists.

What is a line of treatment for cancer?

When oncologist talk about "lines of treatment" they are referring to different approaches to treating cancer at different times. This can be confusing, and example is likely the best way to describe how this works.

What is second line treatment?

Second-line treatment is treatment for a disease or condition after the initial treatment ( first-line treatment) has failed, stopped working, or has side effects that aren't tolerated. It's important to understand "lines of treatment" and how they differ from first line treatment and can play a role in clinical trials.

Why do we use second line therapy?

Second-line or further lines of therapy (third-line, fourth-line, seventh-line, etc.) may be used for a few different reasons: The first-line treatment worked but has since stopped working. The first-line treatment has side effects that are not tolerated.

Why are clinical trials considered a last ditch effort?

Today, many of the medications being evaluated in these trials have been designed to target specific molecular abnormalities in cancer cells. For this reason, they often have fewer side effects than traditional chemotherapy drugs, but are also more likely to be effective for a person participating in a clinical trial.

Why is understanding the line of treatment important?

Understanding line of treatment becomes very important when looking at clinical trials for cancer. Some clinical trials require that people have no previous treatments, whereas others are designed for people who have had inadequate results with a previous treatment.

Is first line treatment tolerated?

The first-line treatment has side effects that are not tolerated

Why are lines of therapy important?

Lines of therapy (LOT) and the number of prior lines of therapy influence the clinical benefit and even the magnitude of response to select regimens.1 They are an important parameter to be determined in retrospective database studies evaluating oncology patients on various chemotherapy/immunotherapy regimens. It is also important to establish LOT regimens for economic outcomes, as resource utilization and costs can then be linked to specific regimens of interest for payers, providers, and patients, helping them to make informed decisions. Since lines of therapy are not explicitly available in claims data, algorithms with rules for initiation, discontinuation, restarting and switching of therapies need to be implemented. This white paper attempts to establish guidelines for determining LOT regimens and durations for retrospective claims studies in oncology.

Is a restart of the same line a LOT?

Regimens that are interrupted can be considered restarts of the same LOT or incremented to the next LOT depending on the length of the interruption. Usually, if the interruption is less than the gap identified as a true discontinuation, then restart of the same line does not increment the LOT. However, if the interruption is longer than the time set for a true discontinuation, then the LOT is incremented. Likewise, if another agent or a combination of agents is given in between the restart of the previous LOT, then the LOT is incremented. In cancers such as multiple myeloma, where rechallenge in relapse setting is quite common, the period of the interruption determines if the LOT is incremented or not. Dose modifications are not considered as increments to the LOT.

What is active release technique?

Active release technique (ART) treats your body’s soft tissue by combining manipulation and movement. The technique’s been around for more than 30 years. ART entails identifying, isolating, and targeting the affected area to break up scar tissue. This promotes blood flow and faster healing of injuries. ART can be used to treat problems with your:

How does active release work?

ART works by breaking up adhesions, which are dense collections of scar tissue that form when muscles and connective tissues are injured. When the scar tissue binds between your muscles, it limits flexibility, causing pain and stiffness in muscles and joints. Sometimes adhesions can also entrap nerves.

How painful is active release?

What to expect from active release technique. ART involves very precise pressure and can be very painful. If you have a low tolerance for pain then you’ll likely find a treatment session to be uncomfortable. It can work in as little as one session for some, though some people may need more than one.

How many sessions does a syringe work?

It can work in as little as one session for some, though some people may need more than one.

What is the Graston technique?

This patented technique is very similar to ART. It also targets adhesions and improves blood flow but uses handheld instruments to provide tissue mobilization.

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