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Learn More...How does Protonix treat esophageal reflux?
Protonix (pantoprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years…
How many milligrams of Protonix should I take for acid reflux?
A US multicenter, double-blind, placebo-controlled study of PROTONIX 10 mg, 20 mg, or 40 mg once daily was conducted in 603 patients with reflux symptoms and endoscopically diagnosed EE of grade 2 or above (Hetzel-Dent scale). In this study, approximately 25% of enrolled patients had severe EE of grade 3, and 10% had grade 4.
What are the guidelines for the treatment of Protonix?
Avoid administration of PPIs for longer than medically indicated. If signs or symptoms consistent with CLE or SLE are noted in patients receiving PROTONIX, discontinue the drug and refer the patient to the appropriate specialist for evaluation. Most patients improve with discontinuation of the PPI alone in 4 to 12 weeks.
How to take Protonix delayed release tablets?
PROTONIX Delayed-Release Tablets 1 You can take PROTONIX tablets with food or on an empty stomach. 2 Swallow PROTONIX tablets whole. 3 If you have trouble swallowing a PROTONIX 40 mg tablet, you can take two 20 mg tablets instead. 4 Do not split, chew, or crush PROTONIX tablets.
How long should you take Protonix for GERD?
If you buy pantoprazole from a pharmacy, you can usually take it for up to 2 weeks. After 2 weeks: if your symptoms have improved, you can take it for another 2 weeks. if your symptoms have not improved or they are worse, speak to a doctor before taking any more pantoprazole.
How long should you take Protonix?
PROTONIX is used in adults: for up to 8 weeks to heal acid-related damage to the lining of the esophagus (erosive esophagitis or EE) and to relieve symptoms caused by gastroesophageal reflux disease (GERD). If needed, your doctor may decide to prescribe another 8 weeks of PROTONIX.
How long can you take Protonix 40 mg?
Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.
How long does it take Protonix to heal esophagitis?
Patients initially received pantoprazole 40 mg daily for 8 weeks and 81% achieved documented healing of erosive esophagitis. All healed patients subsequently received maintenance therapy with pantoprazole 20 mg daily; 82% remained in remission at 6 months.
Can I take Protonix long term?
PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal.
Can you take pantoprazole for years?
A: Pantoprazole is generally safe for long-term use under a doctor's supervision. But there are potential concerns, such as an increased risk of fractures. The best approach is to use the lowest pantoprazole dosage for the shortest amount of time necessary.
What is considered long term use of pantoprazole?
Taking pantoprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk. If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
How do I wean off pantoprazole 40 mg?
Folks who have been taking PPIs for a period of six months might consider tapering down their dose instead of stopping cold turkey. However, you might be wondering how to properly taper down. Try to reduce your dose by 50% every week. Once you are on the lowest dose for one full week, you can try stopping your PPI.
Can I take PPI for years?
While the effectiveness part remains true, concerns have been raised regarding the safety of long term use of PPIs and the serious adverse effects it may cause. Increased risk for gastric cancer, which ranks third among cancer-related mortalities, has been suggested with long term use of PPIs [3].
How long does it take for stomach acid to return to normal?
An antacid or alginate can help until your acid levels return to normal. For most people acid levels return to normal within one to two weeks.
What is the most common side effect of Protonix?
The following are the most commonly reported Protonix side effects: Nausea or vomiting. Diarrhea or constipation. Stomach pain.
Can acid reflux be cured permanently?
Yes, most cases of acid reflux, sometimes referred to as gastroesophageal reflux disease, or GERD, can be cured.
How do I wean myself off pantoprazole?
Folks who have been taking PPIs for a period of six months might consider tapering down their dose instead of stopping cold turkey. However, you might be wondering how to properly taper down. Try to reduce your dose by 50% every week. Once you are on the lowest dose for one full week, you can try stopping your PPI.
What is the most common side effect of Protonix?
The following are the most commonly reported Protonix side effects: Nausea or vomiting. Diarrhea or constipation. Stomach pain.
Can I take pantoprazole every other day?
taking one pill every other day, continue for 2 weeks and then stop. If you are on a higher dose, your doctor may start by prescribing a lower one. In this case, take the lower dose once daily for 2 weeks, then every other day for 2 weeks, then stop.
What are the side effects of Protonix 40 mg?
Common Protonix Side EffectsHeadache.Diarrhea.Nausea.Stomach pain.Vomiting.Gas.Dizziness.Joint pain.
When should you take pantoprazole?
Take pantoprazole tablets immediately before a meal, preferably in the morning. Pantoprazole tablets may be taken with food or on an empty stomach....
Can pantoprazole cause anxiety?
Pantoprazole may cause side effects, but it does not seem to cause anxiety. Some people in clinical trials reported headaches while taking pantopra...
How long does pantoprazole take to work?
Pantoprazole starts to work within 2 and a half (2.5) hours – this is the time it takes for it to block the secretion of acid in the stomach - and...
Pantoprazole vs. omeprazole: What's the difference between them?
Pantoprazole and omeprazole are both medicines from the class of medications called proton pump inhibitors (PPIs). The approved uses for pantoprazo...
Can you take pantoprazole 40 mg twice a day?
The usual dosage for pantoprazole 40mg is 40mg once a day if you are buying it without a prescription or a physician's evaluation of your symptoms....
How long can I take pantoprazole?
You should only take pantoprazole for up to 8 weeks if you are buying it without a prescription or a physician evaluation of your symptoms. This is...
Does pantoprazole cause bloating?
Bloating has been reported as a side effect of regular pantoprazole use. One study reported bloating in 43% of patients taking a similar proton pum...
How long does Protonix last?
For those adult patients who have not healed after 8 weeks of treatment , an additional 8-week course of PROTONIX may be considered. Safety of treatment beyond 8 weeks in pediatric patients has not been established.
What are the side effects of Protonix?
What are the possible side effects of Protonix? Protonix may cause serious side effects, including: severe stomach pain, diarrhea that is watery or has blood in it, sudden pain or difficulty moving your hip, wrist or back, bruising or swelling at the injection site, little or no urination, blood in the urine, swelling,
What is the best medicine for esophagitis?
Protonix is a prescription medicine used to treat the symptoms of esophagitis caused by stomach acid due to gastroesophageal reflux disease or GERD and Zollinger-Ellison syndrome or other conditions causing excess stomach acid. Protonix may be used alone or with other medications.
What is the color of Protonix?
PROTONIX (pantoprazole sodium) Delayed-Release Tablets are supplied as yellow, oval biconvex delayed-release tablets imprinted with PROTONIX (brown ink) on one side containing 40 mg pantoprazole and are available as follows:
How long does it take for pantoprazole to be detected in milk?
Pantoprazole was detectable in milk only 2 and 4 hours after the dose with milk levels of approximately 36 mcg/L and 24 mcg/L, respectively. A milk-to-plasma ratio of 0.022 was observed at 2 hours after drug administration. Pantoprazole was not detectable (<10 mcg/L) in milk at 6, 8 and 24 hours after the dose.
What is the metabolite of pantoprazole?
Pantoprazole is metabolized mainly by CYP2C19 and to minor extents by CYPs 3A4, 2D6, and 2C9. In in vivo drug-drug interaction studies with CYP2C19 substrates (diazepam [also a CYP3A4 substrate] and phenytoin [also a CYP3A4 inducer] and clopidogrel), nifedipine, midazolam, and clarithromycin (CYP3A4 substrates), metoprolol (a CYP2D6 substrate), diclofenac, naproxen and piroxicam (CYP2C9 substrates), and theophylline (a CYP1A2 substrate) in healthy subjects, the pharmacokinetics of pantoprazole were not significantly altered.
Can you take Protonix with other medications?
Protonix may be used alone or with other medications. Protonix belongs to a class of drugs called proton pump inhibitors (PPIs). It is not known if Protonix is safe and effective in children younger than 5 years of age.
How to relieve acid reflux?
For many people, simply changing your diet and lifestyle is enough to relieve symptoms. This may include: Removing foods from your diet that could trigger symptoms of heartburn and/or acid reflux. To name a few: Alcohol. Caffeine. Chocolate.
What is a proton pump inhibitor?
What are proton pump inhibitors (PPIs)? PPIs are a type of drug used to ease the symptoms of acid-related conditions. Some of these conditions include serious acid reflux/heartburn, GERD, peptic ulcers (a sore in the lining of the stomach), and Zollinger-Ellison syndrome, a condition in which tumors in the pancreas cause ...
How long does it take for a PPI to work?
Depending on your diagnosis, your healthcare provider may give you a PPI for only a few weeks, or you may need longer treatment.
What does it mean when your stomach makes too much acid?
When your stomach makes too much acid, you may have symptoms like: These symptoms may mean you have acid reflux and heartburn, which can usually be relieved by antacids and no medical treatment. If symptoms become serious and happen more than once a week, it could mean you have gastroesophageal reflux disease (GERD).
Why does my stomach make acid?
What is acid reflux or GERD? The stomach makes acid to help you digest food and remove bacteria. This is a natural process. In some people, the stomach makes too much acid, which can cause discomfort. When your stomach makes too much acid, you may have symptoms like: Burning in your chest. Regurgitating (bringing up) acid into your throat and mouth.
Can a PPI cause a heart attack?
It is not clear why this may happen, but studies suggest that PPI use may increase this risk. Additionally, those who have had a heart attack and are on blood thinners like clopidogrel (Plavix), can have a repeat heart attack. This is because some PPIs can reduce the function of the blood thinner.
How to reduce acid in throat?
Not eating 2-3 hours before bedtime. Finding positions to sleep in that help reduce acid from reaching your throat. Elevating your head and upper body with pillows or a wedge-shaped support pillow can help. Quitting smoking. Losing weight, if needed.
How long can you use Protonix?
In pediatric patients (under the age of 18 years), there is no safety data on the use of Protonix for more than eight weeks. Erosive esophagitis is uncommon in children, so studying the safety of a proton pump inhibitor for longer periods of time in this age group is challenging.
How long does Protonix last?
Protonix should be stored at 20 to 25 C (68 to 77 F). It may be stored for a brief period to a lower temperature of 15 C (59 F) or a high of 30 C (86 F). In the case of GERD, Protonix is only prescribed for eight weeks or less to start, so refills, for this reason, are not common.
What is Protonix used for?
Protonix is used to treat certain conditions in the stomach and esophagus, such as acid reflux, gastroesophageal reflux disease (GERD), and erosive esophagitis . Protonix is approved for use in adults and children over the age of 5 years. It is most often given orally as a pill, but there is also an oral liquid suspension form ...
What is the drug called that sups the production of acid in the stomach?
Side Effects. Warnings and Interactions. Protonix (generic name pantoprazole) is a type of drug that’s called a proton pump inhibitor. This drug works by lowering the production of acid in the stomach. Protonix is used to treat certain conditions in the stomach and esophagus, such as acid reflux, gastroesophageal reflux disease (GERD), ...
How much glycerin is safe for GERD?
It comes in dosages of 20 milligrams (mg) and 40 mg. Dosages are defined for the treatment of GERD and overactive acid production in adults. However, for children, a safe dosage is only outlined for treating GERD, because a safe dosage for overactive acid production is not established.
Is Protonix a tablet?
However, the doctor that prescribes the drug will specify the dosage, while taking into account age, general health, and the condition for which Protonix is being prescribed. Protonix is a tablet that’s taken orally.
Does proton pump increase methotrexate?
Proton pump inhibitors such as Protonix may cause a serum increase of methotrexate. That means that for those who are taking higher doses of methotrexate, a proton pump inhibitor may increase the risk of methotrexate toxicity. 1 .
How does acid reflux medication work?
How Acid Reflux Medication Works. Nearly all anti acid medications aim to relieve heartburn by reducing the acidity of the reflux. There are a few exceptions, like Gaviscon, which reduces reflux itself. PPI drugs are the most successful group of medication for acid reflux. The reason for their success is simple.
Why is PPI used for acid reflux?
PPI drugs are the most successful group of medication for acid reflux. The reason for their success is simple. They massively reduce the stomach’s acidity. Less acid in the reflux means less irritation for the inflamed esophagus. The result is less heartburn, or even no pain at all.
What happens if you stop taking PPIs?
If you stop taking PPIs abruptly, your body will react with a rebound effect by increasing acid production, which temporarily worsens acid reflux symptoms. These rebound symptoms are the reason proton-pump inhibitors are hard to give up. They are addictive. You may have to endure worsened symptoms for a period to come off the drugs.
How long does B12 last?
Luckily, our body stocks a long-lasting B12 reserve. It can last for years, even when on PPIs, as long as your B12 reserves are good in the first place. Unfortunately, as more and more people take heartburn medication for years or decades, PPI-linked B12 deficiency is increasingly wide-spread these days.
What is the generic name for proton pump inhibitors?
PPIs can be recognized by their suffix “-prazole.”. To the right, you’ll find the most well-known brand names under which that drug is sold. Pantoprazole - Protonix. Esomeprazole - Nexium.
Does heartburn medication increase acid reflux?
[2] Ironically, taking heartburn medication can even increase acid reflux in the long run.
Why is stomach acid important?
Stomach acid is essential for the absorption of many nutrients. Without enough acidity, the stomach cannot break down the food and turn it into absorbable vitamins and minerals. Now that does not mean that you won’t absorb any nutrients if you are on proton-pump inhibitors.
What is aciphex used for?
What is Aciphex? Aciphex (rabeprazole sodium) is a proton pump inhibitor (PPI) to reduce stomach acid and is used for the treatment of gastroesophageal reflux disease (GERD), duodenal ulcers, and used in combination with antibiotics to treat Helicobacter pylori ( H. pylori) bacterial infections in the stomach.
Does RXList.com update drug information?
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Can you take Aciphex with antibiotics?
Your doctor may prescribe antibiotic medicines with Aciphex to help treat a stomach infection and heal stomach (duodenal) ulcers that are caused by bacteria called H. pylori. Make sure you read the patient information that comes with an antibiotic before you start taking it.
Can you take Protonix with apple juice?
Proto nix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal. Protonix Oral Suspension should not be taken in or with water or other liquids, or with other foods. Protonix Oral Suspension should not be chewed or crushed.
Can you take Aciphex with food?
Your doctor will tell you the time of day to take Aciphex, based on your medical condition. Aciphex can be taken with or without food. Your doctor will tell you whether to take this medicine with or without food based on your medical condition. Swallow each Aciphex tablet whole. Do not chew, crush, or split Aciphex tablets.
Uses
Before Taking
- Erosive Esophagitis
Erosive esophagitis is when the lining of the esophagus is inflamed and irritated. This is a problem that may occur as a complication of GERD. GERD is a condition that may cause signs and symptoms such as heartburn (a burning feeling in the chest), regurgitation, and nausea that ma… - Zollinger-Ellison Syndrome
Zollinger-Ellison syndrome is a rare condition that causes the growth of tumors in the pancreas or the duodenum (the first part of the small intestine). These tumors produce a hormone, which, in turn, causes the stomach to overproduce acid. The excess stomach acid can lead to the develop…
Dosage
- The manufacturer has a recommended dosage for adults and children. However, the healthcare provider that prescribes the drug will specify the dosage, while taking into account age, general health, and the condition for which Protonix is being prescribed. Protonix is a tablet that’s taken orally. It comes in dosages of 20 milligrams (mg) and 40 mg. Dosages are defined for the treat…
Side Effects
- Common
Some of the common side effects of Protonix in adults include:1 1. Diarrhea 2. Dizziness 3. Gas 4. Headache 5. Joint pain 6. Nausea 7. Stomach-area (abdominal) pain 8. Vomiting The common side effects of Protonix in children include:1 1. Diarrhea 2. Fever 3. Headache 4. Rash 5. Stom…
Warnings and Interactions
- Protonix is associated with certain types of severe adverse effects and events. People who are taking Protonix should let their healthcare provider know if they’ve experienced any of the signs and symptoms associated with these serious side effects.1